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Transient thyrotoxicosis during nivolumab treatment.
van Kooten, M J; van den Berg, G; Glaudemans, A W J M; Hiltermann, T J N; Groen, H J M; Rutgers, A; Links, T P.
Neth J Med ; 75(5): 204-207, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28653941

ABSTRACT

Two patients presented with transient thyrotoxicosis within 2-4 weeks after starting treatment with nivolumab. This thyrotoxicosis turned into hypothyroidism within 6-8 weeks. Temporary treatment with a beta blocker may be sufficient.


Subject(s)
Antibodies, Monoclonal/adverse effects , Antineoplastic Agents/adverse effects , Hypothyroidism/chemically induced , Lung Neoplasms/drug therapy , Thyrotoxicosis/chemically induced , Aged , Carcinoma, Non-Small-Cell Lung/drug therapy , Carcinoma, Squamous Cell/drug therapy , Female , Humans , Middle Aged , Nivolumab
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