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1.
J Fam Psychol ; 2024 Jun 06.
Article in English | MEDLINE | ID: mdl-38842872

ABSTRACT

The purpose of this study was to assess the factor structure and the measurement invariance of the Coparenting Relationship Scale (CRS) across 10 countries based on the seven-factor coparenting model (i.e., Coparenting Agreement, Coparenting Closeness, Exposure to Conflict, Coparenting Support, Endorsement of Partner's Parenting; Division of Labor) proposed by Feinberg (2003). The results of research on coparenting from numerous countries have documented its foundational importance for parent mental health, family relationship quality, child development, and psychopathology. Yet, a cross-country perspective is still lacking. Such a perspective can provide insight into which dimensions of coparenting are universally recognized and which are especially prone to variation. A unique multinational data set, comprised of 15 individual studies collected across 10 countries (Belgium, Brazil, China, Israel, Italy, Japan, Portugal, Switzerland, Turkey, USA) in nine languages was established (N = 9,292; 51.1% mothers). Measurement invariance analyses were conducted. A six-factor structure (original seven factors minus Division of Labor) of the measure was consistent across the different contexts and measurement invariance was achieved at the configural level. There was no support for metric or scalar invariance. These findings provide a basis for the CRS to be used across countries and should inspire future quantitative and qualitative research in cross-country coparenting research to understand what aspects are universal and what aspects of coparenting are linked to specific material, relational, or ideational conditions that underlie high-quality coparenting. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

2.
Dev Psychobiol ; 66(5): e22496, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38689124

ABSTRACT

The current study explored longitudinally whether oxytocin receptor gene methylation (OXTRm) changes moderated the association between parental sensitivity changes and children's attachment changes over three waves. Six hundred six Flemish children (10-12 years, 42.8%-44.8% boys) completed attachment measures and provided salivary OXTRm data on seven CpG sites. Their parents reported their sensitive parenting. Results suggest that OXTRm changes hardly link to attachment (in)security changes after the age of 10. Some support was found for interaction effects between parental sensitivity changes and OXTRm changes on attachment changes over time. Effects suggest that for children with increased OXTRm in the promotor region and decreased methylation in the inhibitor region over time, increased parental sensitivity was associated with increased secure attachment and decreased insecure attachment over time.


Subject(s)
DNA Methylation , Object Attachment , Receptors, Oxytocin , Humans , Receptors, Oxytocin/genetics , Male , Female , Longitudinal Studies , Child , Parenting , Parent-Child Relations , Child Development/physiology
3.
Fam Syst Health ; 2024 Apr 25.
Article in English | MEDLINE | ID: mdl-38661643

ABSTRACT

BACKGROUND: The aim of this study was to investigate the link between parenting and parents' perspectives on health-related decision making for adolescents. During adolescence, there is a gradual increase in responsibility and autonomy, which influences parenting behavior and child development. Understanding how parenting is associated with parents' views on medical decision making is crucial in the context of the parent-child-physician triad. This study was the first to explore parenting and parents' views on adolescent health care decision making. We compare Belgian and Dutch parents-two countries selected for their different legal frameworks on medical adolescent decision making. METHOD: An online questionnaire surveyed 984 Belgian and 992 Dutch parents (ages 35-55) with at least one child. Analytical methods included t tests, structural equation modeling, and latent profile analysis. RESULTS: Parents considered adolescents to be competent decision makers at 16.7 years old. Dutch parents granted autonomy at younger ages than Belgian parents. Parents with high behavioral expectations granted autonomy to adolescents at higher ages, while those high in autonomy support and punishment granted autonomy at lower ages. When classifying parents into profiles, we distinguished four types: highly permissive, moderately permissive, moderately restrictive, and highly restrictive groups. The majority of the sample was classified into moderately and highly restrictive profiles. CONCLUSION: The study highlighted the importance of providing parents with education and support on adolescent development and autonomy. Parenting practices that encourage autonomy and support open communication between parents and adolescents may contribute to a more trusting and supportive parent-child context for adolescent medical decision making. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

4.
Acta Psychol (Amst) ; 244: 104197, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38428227

ABSTRACT

The current study aimed to examine the psychometric properties of the newly developed Mobile Phone Parenting Practices Questionnaire (MPPPQ) in a sample of Chinese migrant parents experiencing long-term parent-child separation. A total of 547 rural-to-urban migrant parents with 3-to-6-year-old children left in rural hometowns were recruited online and completed electronic questionnaires. Exploratory (N1 = 288) and confirmatory (N2 = 259) factor analyses were successively used to identify the factor structure. The results indicated that the MPPPQ consists of six dimensions, responsivity, autonomy granting, proactive control, directive control, psychological control, and harsh punitive control, with a good model fit. The dimensions showed good internal consistency and composite reliability. By examining associations with constructs of the Parenting Styles and Dimensions Questionnaire, convergent validity was well established. The criterion validity of the MPPPQ was confirmed by its associations with parental stress, indicated by the Parental Stress Scale. This initial examination of the MPPPQ conveys that it holds good psychometric properties and may contribute to theoretical, methodological, and practical applications regarding parenting in the context of family separation and media use.


Subject(s)
Parenting , Humans , Child , Child, Preschool , Parenting/psychology , Psychometrics , Reproducibility of Results , Surveys and Questionnaires , China
5.
J Youth Adolesc ; 52(10): 1995-2011, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37470939

ABSTRACT

A broad range of factors have been associated with the development of adolescent loneliness. In the family context, a lack of parental support and high levels of parental psychological control have systematically been linked to loneliness. On the biological level, DNA methylation (which is an epigenetic process that suppresses gene expression) is believed to play a role in the development of loneliness. Specifically, high levels of DNA methylation in genes that play an important role in the functioning of the human stress response system are believed to elevate the risk of loneliness. Moreover, DNA methylation levels in these stress-related genes can be influenced by stressful environmental factors, suggesting a potential mediating role of DNA methylation in the association between parenting behaviors and loneliness. The current 3-year longitudinal study is the first study to examine the potential bidirectional longitudinal associations between loneliness, DNA methylation in stress-related genes, and both perceived parental support and psychological control. Furthermore, we explored the potential mediating role of DNA methylation in stress-related genes in the associations between perceived parenting and loneliness. The sample comprised 622 early adolescents (55% girls, Mage T1 = 10.77 years, SDage T1 = 0.48) who were followed from Grade 5 to 7. Parental support, psychological control, and loneliness were assessed annually by adolescent self-report questionnaires and DNA methylation was determined from saliva samples. Cross-Lagged Panel Models (CLPM) revealed that higher levels of loneliness predicted lower perceived parental support and higher perceived psychological control over time, as well as higher DNA methylation in some stress-related genes, that is, the glucocorticoid receptor gene (NR3C1) and the brain-derived neurotrophic factor (BDNF). In addition, higher NR3C1 methylation was predictive of lower perceived parental support and higher psychological control over time. No evidence was found for a mediating role of DNA methylation. Overall, our longitudinal findings challenge the current focus on DNA methylation and parenting behaviors as risk factors for adolescent loneliness. Instead, they suggest that the less considered direction of effects, which implies that loneliness predicts DNA methylation and aspects of parenting such as support and psychological control, should receive greater attention in future research.


Subject(s)
DNA Methylation , Loneliness , Female , Humans , Adolescent , Child , Infant , Male , Loneliness/psychology , Longitudinal Studies , Parenting/psychology , Parents
6.
Child Dev ; 94(4): 941-955, 2023.
Article in English | MEDLINE | ID: mdl-36806174

ABSTRACT

The current study examined whether secure base script knowledge can buffer against higher concurrent externalizing problems and against relative increases in externalizing problems associated with cumulative family stress. We conducted a one-year longitudinal study with two waves between 2017 and 2019 in which 272 Dutch-speaking Western European children from Flanders (47.8% boys, M age = 10.20 , SD age = 0.60 ) participated. Secure base script knowledge was associated with lower concurrent externalizing problems (f2  = 0.03). High levels of secure base script knowledge also buffered against relative increases in externalizing problems associated with cumulative family risk (f2  = 0.02). These findings suggest that secure base script knowledge can mitigate the negative effects of a stressful family environment on externalizing problems.


Subject(s)
Anxiety , Object Attachment , Male , Child , Humans , Female , Longitudinal Studies , Protective Factors , Ethnicity
7.
Psychoneuroendocrinology ; 150: 106045, 2023 04.
Article in English | MEDLINE | ID: mdl-36796155

ABSTRACT

BACKGROUND: Daily Hassles (DH) or daily stress - is a mild type of stressor with unique contributions to psychological distress. Yet, most prior studies that investigate the effects of stressful life experiences focus on childhood trauma or on early life stress and little is known about the effects of DH on epigenetic changes in stress system related genes and on the physiological response to social stressors. METHODS: In the present study, conducted among 101 early adolescents (mean age = 11.61; SD = 0.64), we investigated whether Autonomic Nervous System (ANS) (namely heart rate and heart rate variability) and Hypothalamic-Pituitary-Adrenal (HPA) axis functioning (measured as cortisol stress reactivity and recovery) are associated with DNA methylation (DNAm) in the glucocorticoid receptor gene (NR3C1), the level of DH and their interaction. To assess the stress system functioning the TSST protocol was used. RESULTS: Our findings show that higher NR3C1 DNAm in interaction with higher levels of daily hassles, is associated with blunted HPA axis reactivity to psychosocial stress. In addition, higher levels of DH are associated with extended HPA axis stress recovery. In addition, participants with higher NR3C1 DNAm had lower ANS adaptability to stress, specifically lower parasympathetic withdrawal; for heart rate variability this effect was strongest for participants with higher level of DH. CONCLUSIONS: The observation that interaction effects between NR3C1 DNAm levels and daily stress on the functioning of the stress-systems, are already detectable in young adolescents, highlights the importance of early interventions, not only in the case of trauma, but also daily stress. This might help to prevent stress-induced mental and physical disorders later in life.


Subject(s)
DNA Methylation , Hypothalamo-Hypophyseal System , Humans , Adolescent , Child , Hypothalamo-Hypophyseal System/metabolism , Pituitary-Adrenal System/metabolism , Stress, Psychological , Autonomic Nervous System , Hydrocortisone , Receptors, Glucocorticoid/metabolism
8.
Crisis ; 44(2): 100-107, 2023 Mar.
Article in English | MEDLINE | ID: mdl-34915734

ABSTRACT

Background: A growing body of empirical research shows that suicidal behaviors are prevalent in childhood. Yet, few studies have examined risk factors related to suicidal ideation (SI) among children aged 12 and younger. Aims: The current study addresses this gap. Method: A questionnaire was filled out by 1,350 Flemish primary caregivers (94.7% mothers) of 9-year-old children (50.4% boys, Mage = 9.45). Their responses were analyzed using logistic regression and independent samples t tests. Results: The presence of passive SI was reported in 10.5% of the children. A psychiatric, developmental, or behavioral condition (or multiple conditions), a learning disorder, impulsivity, aggression, and experiencing multiple stressful family life events were discovered as potential risk factors of passive SI in childhood. Limitations: The cross-sectional nature of this study meant that causality could not be inferred. In addition, it was based on reports of primary caregivers, rather than on reports from the children themselves. Conclusion: These new empirical findings can be used for the development of prevention programs and be taken into account in risk assessments of SI in clinical practice. Confirmation of our findings in a longitudinal child-reported study is needed.


Subject(s)
Mental Disorders , Suicidal Ideation , Male , Humans , Child , Female , Cross-Sectional Studies , Risk Factors , Family Relations/psychology
9.
Int J Psychophysiol ; 176: 36-53, 2022 06.
Article in English | MEDLINE | ID: mdl-35301026

ABSTRACT

Young adolescents are hypothesized to differ in their environmental sensitivity, at both phenotypic (i.e., Sensory Processing Sensitivity [SPS]) and physiological (i.e., biological stress response) level. This is the first study that investigated whether individual differences in environmental sensitivity at physiological level could be predicted by individual differences at phenotypic level, as measured with the HSC scale. A total of 101 adolescents (Mage = 11.61, SDage = 0.64) participated in a standardized social stress task (i.e., Trier Social Stress Task-Modified version for children and adolescents (TSST-M)). From baseline to the end of recovery, eight cortisol samples were collected, as well as a continuous measure of Autonomic Nervous System activity. Adolescents reported on SPS and on perceived stress before, during, and after TSST-M. As a follow-up analysis, the quality of the environment, the possible overlap with Neuroticism, and several covariates were considered. Multilevel models were used to investigate within- and between-person differences in stress reactivity across different systems. Results indicate significant individual differences in heart rate, heart rate variability, skin conductance, cortisol, and perceived stress in response to the TSST-M. Only for perceived stress significant differences in SPS were observed, with more sensitive individuals perceiving more negative and less positive affect. For environmental quality and the interaction between SPS and Neuroticism results showed higher recovery rates of heart rate in high quality environments and stronger cortisol responses for adolescents scoring high on both SPS and Neuroticism. Potential explanations for these findings and implications for current theorizing on environmental sensitivity are discussed.


Subject(s)
Hydrocortisone , Individuality , Adolescent , Autonomic Nervous System , Child , Heart Rate/physiology , Humans , Hypothalamo-Hypophyseal System , Infant , Pituitary-Adrenal System/chemistry , Saliva/chemistry , Stress, Psychological
10.
J Appl Res Intellect Disabil ; 35(2): 531-536, 2022 Mar.
Article in English | MEDLINE | ID: mdl-34845791

ABSTRACT

BACKGROUND: It is generally acknowledged that parent social support is an important target for intervention. To explore the specific needs of parents of young children with a significant cognitive and motor developmental delay (SDD), we aim to chart the sources and perceived sufficiency of the social support they receive. METHOD: Within the context of a broader project, 42 parents of a young child with SDD filled out a questionnaire on contextual factors, including information on social support. RESULTS: The majority of parents reported to receive (more than) sufficient support. Insufficiency is primarily reported with regard to practical support. Apart from the partner, grandparents of the child were the most common source of support. CONCLUSIONS: This study confirms the importance of professional support and work-life balance within this specific target group. Specific attention for practical support needs seems warranted considering the high basic care needs of these children.


Subject(s)
Intellectual Disability , Motor Skills Disorders , Child , Child, Preschool , Cognition , Humans , Parents/psychology , Social Support
11.
Assessment ; 29(4): 607-629, 2022 06.
Article in English | MEDLINE | ID: mdl-33426925

ABSTRACT

Children differ in their sensitivity to positive and negative environmental influences, which can be measured with the Highly Sensitive Child (HSC) scale. The present study introduces the HSC-21, an adaptation of the original 12 item scale with new items and factor structure that are meant to be more informative than the original ones. The psychometric properties of the HSC-21 were investigated in 1,088 children across Belgium and the Netherlands, including child and mother reports. Results showed evidence for (a) bifactor model with a general sensitivity factor and two specific factors (i.e., Ease of Excitation-Low Sensory Threshold and Aesthetic Sensitivity); (b) (partial) measurement invariance across gender, developmental stage, country, and informants; (c) moderate child-mother agreement; (d) good reliability; (e) normally distributed item scores; and (f) meaningful associations with personality and temperament across both samples. No evidence was found for HSC-21 as a moderator in the relationship between parenting and problem behaviors.


Subject(s)
Problem Behavior , Adolescent , Female , Humans , Psychometrics/methods , Reproducibility of Results , Surveys and Questionnaires , Temperament
12.
Res Child Adolesc Psychopathol ; 49(10): 1387-1401, 2021 10.
Article in English | MEDLINE | ID: mdl-34021460

ABSTRACT

The etiology of borderline personality pathology has consistently been framed as an interactional process between child vulnerability (i.e. emotional sensitivity and reactivity; Linehan, 1993) and invalidating parenting strategies, which evolves into increased emotion dysregulation and disinhibited behavior of the child and in turn activates more parental invalidation. Despite the strong theoretical base in support of these high-risk parent-child transactions, invalidating parenting behaviors have mostly been explored as a cause of child dysregulation and disinhibition, rather than as a result of child-driven effects. Also, most transactional research in this regard focused at differences between families, thereby not addressing potential changes within families across time. The current study therefore examines bidirectional between- and within-family effects of childhood borderline-related traits and maternal invalidation in the sensitive developmental phase of pre-adolescence (n = 574; 54.4% girls) along three assessment points. Cross-Lagged Panel Models and Random-Intercept Cross-Lagged Panel Models indicated detrimental parenting effects of invalidation on subsequent development in borderline-related traits of the child both between and within families, and additional child-driven effects for subsequent invalidating parenting strategies within families. Beyond these transactions between borderline-related traits and parenting, the current study also indicates significant differences in the direction of effects when exploring transactions between more common dimensions of child internalizing/externalizing symptomatology and parental invalidation, suggesting a more substantial parenting etiology in the developmental process of borderline traits throughout pre-adolescence. Future longitudinal research may explore to what extent the transactional nature of borderline personality traits during important developmental stages indeed holds unique aspects compared to more common manifestations of symptomatology at young age.


Subject(s)
Borderline Personality Disorder , Parenting , Adolescent , Female , Humans , Male , Parent-Child Relations , Parents , Prospective Studies
13.
Front Psychol ; 12: 579810, 2021.
Article in English | MEDLINE | ID: mdl-33986705

ABSTRACT

Children's readiness for school is often threatened by the occurrence of both externalizing and internalizing problems. Previous research has shown that Positive Behavioral Interventions and Supports (PBIS) is particularly effective for fostering children's behavioral skills and reducing externalizing problems. However, whether PBIS can enhance children's emotional skills and reduce internalizing problems is less clear. Therefore, TIME-IN was developed, which extends PBIS by also including emotional support systems. It was tested whether TIME-IN was effective for (a) improving emotion regulation and (b) reducing depressive symptoms. Furthermore, it was tentatively explored whether TIME-IN is accompanied by more than natural fluctuations in both children's externalizing and internalizing problems. The effectiveness of TIME-IN was evaluated in a non-randomized study, in which an intervention group was compared with a matched control group. Both research questions were addressed in a sample consisting of 81 children between 8 and 12 years of age with special educational needs. Questionnaires for teachers (i.e., TRF), children (i.e., FEEL-KJ and CDI), and their parents (i.e., CBCL) were administered at the beginning (T0) and the end of the school year (T1) using multi-informant assessment. Only indicative evidence was found for the hypothesis that TIME-IN improved children's emotion regulation. Practical implications, strengths, and limitations were discussed. Clinical Trial Registration: This work was retrospectively registered at International Standard Registered Clinical/soCial sTudy Number (ISRCTN) registry ISRCTN54456609 (Weymeis, 2017). Registered 28 March 2017.

14.
Personal Disord ; 12(6): 503-513, 2021 11.
Article in English | MEDLINE | ID: mdl-33856835

ABSTRACT

Children with a constellation of dark traits may be particularly challenging to parents because these traits are associated with an increased chance for parents to lose a supportive attitude in dealing with the child's difficultness and to turn instead toward punishing strategies. The present study looks with more detail into the construct of parental punishment and examines differences and similarities in the effects of physical (harsh) versus nonphysical (corrective) discipline on the developmental course of childhood five-factor model-based dark traits across a 10-year time span. Data were drawn from an ongoing (masked for review) longitudinal study, including five assessment points across 10 years (Ntime 1 = 720, 54.4% girls, age range Time 1 = 8-14.78 years, M = 10.73, SD = 1.39). Latent growth modeling suggested significant differences between both kinds of parental discipline in terms of contrasting effects on subsequent growth in dark traits and also showed a number of age-and gender-specific effects of parental discipline on the developmental course of dark traits. These findings underscore the relevance of a more differentiated perspective on effects of parental punishment in understanding childhood maladaptive trait outcomes and may offer fruitful guidelines for the development of intervention programs targeting children that are difficult to manage. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Parents , Punishment , Adolescent , Child , Female , Humans , Infant , Longitudinal Studies , Male , Phenotype
15.
Brain Sci ; 11(2)2021 Feb 04.
Article in English | MEDLINE | ID: mdl-33557123

ABSTRACT

Theory and research both point at epigenetic processes affecting both parenting behavior and child functioning. However, little is known about the convergence of mother and child's epigenetic patterns in families. Therefore, the current study investigated epigenetic covariance in mother-child dyads' methylation levels regarding four stress-regulation related genes (5HTT, NR3C1, FKBP5, and BDNF). Covariance was tested in a general population sample, consisting of early adolescents (Mage = 11.63, SDage = 2.3) and mothers (N = 160 dyads). Results showed that mother and offspring 5HTT and NR3C1 methylation patterns correlated. Furthermore, when averaged across genes, methylation levels strongly correlated. These findings partially supported that child and parent methylation levels covary. It might be important to consider this covariance to understand maladaptive parent-child relationships.

16.
Article in English | MEDLINE | ID: mdl-33499304

ABSTRACT

In two independent studies, we aimed to examine the extent to which teacher and peer nominations of loneliness are associated with children's and adolescents' self-reported loneliness, respectively. Additionally, we examined whether loneliness nominations from teachers and peers were informative above and beyond peer status and social behaviors associated with loneliness. In Study 1 (N = 1594, Mage = 9.43 years), teacher nominations of loneliness showed a small to moderate correlation with children's self-reported loneliness as assessed using the Loneliness and Social Dissatisfaction Questionnaire (LSDQ). The results of a hierarchical regression analysis showed that teacher nominations of loneliness predicted children's self-reported loneliness above and beyond teacher nominations of peer status and social behaviors. In Study 2 (N = 350, Mage = 13.81 years), peer nominations of loneliness showed a small to moderate correlation with adolescents' self-reported loneliness as assessed using the peer-related loneliness subscale of the Loneliness and Aloneness Scale for Children and Adolescents (LACA). The results of a hierarchical regression analysis showed that peer nominations of loneliness predicted adolescents' self-reported loneliness above and beyond peer nominations of peer status and social behaviors. We conclude that loneliness nominations are valuable, but caution is needed when they are used exclusively to identify lonely children and adolescents.


Subject(s)
Loneliness , Peer Group , Adolescent , Child , Humans , Interpersonal Relations , Schools , Self Report
17.
J Adolesc ; 85: 21-31, 2020 12.
Article in English | MEDLINE | ID: mdl-33035916

ABSTRACT

INTRODUCTION: Empathy consists of a cognitive and an affective component, of which it is thought that there are gender differences. Previous studies also suggest that maternal and paternal support play a more prominent role in the development of an adolescent's affective and cognitive empathy, respectively. Besides the environmental factor, that is parenting, adolescent personality, and more specifically, agreeableness, is closely linked to both empathy and support, but this interplay was not extensively investigated longitudinally. The present study investigated the transactional associations among parental support, adolescent agreeableness, and adolescent empathy. More specifically, we examined (a) whether maternal/paternal support is differentially associated with cognitive/affective empathy, while taking into account adolescent agreeableness and (b) whether adolescent agreeableness still predicts empathy, while taking into account parental support. METHODS: Data from 993 Belgian adolescents (MageT1 = 13.96 years; [12.6-18.4]) and their parents across four time points were used in a random intercept cross-lagged panel model. RESULTS: At the between-person level, maternal support was associated with affective, but not cognitive empathy, whereas agreeableness was associated with maternal and paternal support as well as with both types of empathy. At the within-person level, affective empathy predicted cognitive empathy one wave later. CONCLUSIONS: At a population level, agreeableness and support are both important in adolescent empathy development with limited evidence for the differential roles of mothers and fathers. Within participants, affective empathy, and not parental support or agreeableness, predicted cognitive empathy.


Subject(s)
Adolescent Development , Empathy , Parent-Child Relations , Adolescent , Female , Humans , Male , Parenting/psychology , Sex Factors , Surveys and Questionnaires
18.
Eur Psychiatry ; 63(1): e64, 2020 06 08.
Article in English | MEDLINE | ID: mdl-32507125

ABSTRACT

BACKGROUND: Social anxiety symptoms (SAS) are among the most common mental health problems during adolescence, and it has been shown that parenting influences the adolescent's level of social anxiety. In addition, it is now widely assumed that most mental health problems, including social anxiety, originate from a complex interplay between genes and environment. However, to date, gene-environment (G × E) interactions studies in the field of social anxiety remain limited. In this study, we have examined how 274 genes involved in different neurotransmission pathways interact with five aspects of perceived parenting as environmental exposure (i.e., support, proactive control, psychological control, punitive control, and harsh punitive control) to affect SAS during adolescence. METHODS: We have applied an analytical technique that allows studying genetic information at the gene level, by aggregating data from multiple single-nucleotide-polymorphisms within the same gene and by taking into account the linkage disequilibrium structure of the gene. All participants were part of the STRATEGIES cohort of 948 Flemish adolescents (mean age = 13.7), a population-based study on the development of problem behaviors in adolescence. Relevant genes were preselected based on prior findings and neurotransmitter-related functional protein networks. RESULTS: The results suggest that genes involved in glutamate (SLC1A1), glutathione neurotransmission (GSTZ1), and oxidative stress (CALCRL), in association with harsh punitive parenting, may contribute to social anxiety in adolescence. Isolated polymorphisms in these genes have been related to anxiety and related disorders in earlier work.Conclusions: Taken together, these findings provide new insights into possible biological pathways and environmental risk factors involved in the etiology of social anxiety symptoms' development. CONCLUSIONS: Taken together, these findings provide new insights into possible biological pathways and environmental risk factors involved in the etiology of social anxiety symptoms' development.


Subject(s)
Anxiety/genetics , Anxiety/psychology , Gene-Environment Interaction , Parenting/psychology , Phobia, Social/genetics , Phobia, Social/psychology , Adolescent , Belgium , Child , Female , Humans , Male , Polymorphism, Single Nucleotide , Problem Behavior
19.
Res Dev Disabil ; 103: 103672, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32502925

ABSTRACT

Knowledge on the long-term interactive interplay between children with a significant cognitive and motor developmental delay and their parents is very scarce. We aimed to characterize the (in)variability and potential mutual influence of parent's interactional style and child interactive engagement throughout early childhood. Every six months over the course of two years, thirty-five parent-child dyads (children aged 6-59 months) living in Flanders (Belgium) or the Netherlands were video-taped during a 15-minute unstructured play situation. Video-taped observations were scored using the Child and Maternal Behavior Rating Scales. No consistent group-level trend was found. Within singular interactions, parent's responsive behavior and child interactive engagement (attention and initiation) seem to be strongly related. Initial child initiation seems to positively predict parents' achievement orientation and directive behavior two years later. Parental responsiveness might be an effective interactional strategy to increase child engagement and higher levels of engagement in children possibly can facilitate parental responsiveness within a concrete interaction. The more initiative children show, the more parents might have hope for developmental benefits resulting from a directive/achievement oriented approach. Further research is warranted applying more differentiated and dynamically evaluated outcome measures and a longer follow-up time frame, with specific attention to inter-individual differences.


Subject(s)
Cognition , Parents , Belgium , Child , Child Behavior , Child, Preschool , Female , Humans , Longitudinal Studies , Netherlands , Parent-Child Relations
20.
J Res Adolesc ; 30 Suppl 2: 333-348, 2020 02.
Article in English | MEDLINE | ID: mdl-30697859

ABSTRACT

Not much is known regarding underlying biological pathways to adolescents' loneliness. Insight in underlying molecular mechanisms could inform intervention efforts aimed at reducing loneliness. Using latent growth curve modeling, baseline levels and development of loneliness were studied in two longitudinal adolescent samples. Genes (OXTR, OXT, AVPR1A, AVPR1B) were examined using SNP-based, gene-based, and polygenic risk score (PRS) approaches. In both samples, SNP- and gene-based tests showed involvement of the OXTR gene in development of loneliness, though, significance levels did not survive correction for multiple testing. The PRS approach provided no evidence for relations with loneliness. We recommend alternative phenotyping methods, including environmental factors, to consider epigenetic studies, and to examine possible endophenotypes in relation to adolescents' loneliness.


Subject(s)
Anxiety/genetics , Depression/genetics , Loneliness , Adolescent , Anxiety/diagnosis , Depression/diagnosis , Female , Genome-Wide Association Study , Humans , Male , Polymorphism, Single Nucleotide , Receptors, Oxytocin , Receptors, Vasopressin , Surveys and Questionnaires
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