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1.
Ned Tijdschr Geneeskd ; 152(9): 473-7, 2008 Mar 01.
Article in Dutch | MEDLINE | ID: mdl-18389875

ABSTRACT

Anamnestic incidences of four patients have highlighted the potential risk ofexposure to rabies. The first patient was a 30-year-old woman who rescued a bat from the mouth of her dog; it bit her on the right wrist. In the Netherlands, bats may be infected with the Lyssa virus. The Preparedness and Response Unit (PRU) of the Centre for Infectious Disease Control (CIDC) advised human rabies immunoglobulin (HRIG) and a full vaccination programme. The second patient was a 37-year-old woman, who caught a 'sick' squirrel and was subsequently bitten on her left hand. The advice was not to use post exposure prophylaxis since rabies is not prevalent amongst squirrels in the Netherlands. The third patient, a 55-year-old man, was bitten on his right calf by a dog in Sri Lanka. He was treated with HRIG and given the full vaccination course. The fourth patient was a 14-month-old boy who was scratched on the face by a cat in Turkey. He immediately received the first vaccination and upon return to the Netherlands was treated with HRIG and the other vaccinations. All patients remained without symptoms. A structured approach for risk assessment of each potential rabies incident is possible. It requires balancing a number of criteria: the species of animal, the endemicity of rabies in a country, the observed health or vaccination status of an animal, whether the animal can be tested for rabies, if the exposure was provoked or unprovoked, the type of injury and its location on the body of the injured, and the time interval between administration of HRIG and vaccine. In the Netherlands all health care providers are expected to perform a proper risk assessment. They may seek advice from regional health departments (Municipal Health Services), who, in turn, can be assisted by the PRU. HRIG and vaccine are only provided by the National Vaccine Institute in Bilthoven.


Subject(s)
Environmental Exposure , Rabies Vaccines/administration & dosage , Rabies/epidemiology , Risk Assessment/methods , Adult , Animals , Female , Humans , Immunoglobulins/administration & dosage , Incidence , Infant , Male , Middle Aged , Netherlands/epidemiology , Rabies/transmission , Rabies/veterinary , Rabies virus/immunology , Travel , Treatment Outcome , Zoonoses
2.
Ned Tijdschr Geneeskd ; 148(43): 2136-40, 2004 Oct 23.
Article in Dutch | MEDLINE | ID: mdl-15553360

ABSTRACT

UNLABELLED: EPIDEMIOLOGICAL OBSERVATION: On a warm day, during a barbecue that was attended by over 100 guests, a large number became rapidly ill with signs of acute gastroenteritis within a few hours after eating the prepared food. The characteristic symptoms were nausea, vomiting, syncope and in some cases in a later stage, diarrhoea. Sixty patients were transferred to hospitals. INVESTIGATION: Investigation revealed that the cause of this outbreak of gastroenteritis was an enterotoxin-A-producing strain of Staphylococcus aureus in a noodle dish. Both the food residues and the faeces from patients contained genotypically identical strains of S. aureus. They all had the gene for the gastroenteritis-inducing enterotoxin A from S. aureus. CONCLUSION: This case shows that the timely involvement of the different health authorities responsible for intervening in explosions of food poisoning is crucial for the clarification and treatment of such large-scale outbreaks. In the investigation of this outbreak, the municipal health authority co-operated with regional laboratories and the Food and Consumer Product Safety Authority/Inspectorate for Health Protection and Veterinary Public Health.


Subject(s)
Enterotoxins/biosynthesis , Staphylococcal Food Poisoning/epidemiology , Staphylococcus aureus/isolation & purification , Acute Disease , Disease Outbreaks , Enterotoxins/genetics , Food Microbiology , Gastroenteritis/epidemiology , Humans , Netherlands/epidemiology , Staphylococcal Food Poisoning/etiology , Staphylococcus aureus/genetics , Staphylococcus aureus/metabolism
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