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Tijdschr Diergeneeskd ; 119(21): 634-6, 1994 Nov 01.
Article in Dutch | MEDLINE | ID: mdl-7974451

ABSTRACT

Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 micrograms/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 micrograms/kg used by milk-testing stations and the European limit (MRL) of 100 micrograms/kg. Milk from cows treated with lugol did not cause inhibition in the plate test.


Subject(s)
Cattle Diseases/drug therapy , Cattle/metabolism , Endometritis/veterinary , Iodine Compounds/pharmacokinetics , Oxytetracycline/pharmacokinetics , Puerperal Disorders/veterinary , Administration, Topical , Animals , Endometritis/drug therapy , Female , Iodine Compounds/administration & dosage , Oxytetracycline/administration & dosage , Puerperal Disorders/drug therapy , Uterus
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