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C R Acad Hebd Seances Acad Sci D ; 287(13): 1259-62, 1978 Nov 13.
Article in French | MEDLINE | ID: mdl-105824

ABSTRACT

(-)Ephedrine, (+) Ephedrine, (-) psi ephedrine and (+) psi ephedrine inhibit both the neuronal and extraneuronal uptakes of noradrenaline in isolated Rabbit heart. (-) ephedrine is the most active isomer for the inhibition of both neuronal and extraneuronal uptakes. The relative inhibition potential of the three other isomers is not the same when applied to one or other uptake.


Subject(s)
Ephedrine/pharmacology , Myocardium/metabolism , Norepinephrine/metabolism , Animals , In Vitro Techniques , Neural Inhibition/drug effects , Rabbits , Structure-Activity Relationship
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