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1.
Appl Opt ; 55(17): 4713-9, 2016 Jun 10.
Article in English | MEDLINE | ID: mdl-27409030

ABSTRACT

We report on the recently completed 400 TW upgrade to the Scarlet laser at The Ohio State University. Scarlet is a Ti:sapphire-based ultrashort pulse system that delivers >10 J in 30 fs pulses to a 2 µm full width at half-maximum focal spot, resulting in intensities exceeding 5×1021 W/cm2. The laser fires at a repetition rate of once per minute and is equipped with a suite of on-demand and on-shot diagnostics detailed here, allowing for rapid collection of experimental statistics. As part of the upgrade, the entire laser system has been redesigned to facilitate consistent, characterized high intensity data collection at high repetition rates. The design and functionality of the laser and target chambers are described along with initial data from commissioning experimental shots.

2.
Rev Sci Instrum ; 82(3): 033506, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21456736

ABSTRACT

Thomson parabola spectrometers are used to characterize MeV ion beams produced in high intensity laser interactions. These spectrometers disperse multiple ion species according to their charge to mass ratio through the use of parallel electric and magnetic fields. Analytical solutions for ion deflection in electric and magnetic fields have been used to extract ion spectra with the assumption that fringing effects are negligible. Experimental space restrictions and dynamic range requirements necessitate designs that stress the analytical assumptions. Depending on design parameters, the error in the analytical assumption can be comparable to the energy resolution. Estimates are provided to approximate the error on the total ion deflection. A method for modeling ion trajectories including fringing effects is presented using software freely available or in common use. The magnetostatic fields are modeled in 3D, including material properties of nearby magnetic materials using RADIA. Electrostatic fields are modeled in 2D for a spectrometer implementing angled plates using the partial differential equation toolbox in MATLAB(®). Using these models to calculate the ion trajectory allows for analysis of a Thomson parabola spectrometer with an arbitrary field configuration.

3.
Phys Rev Lett ; 104(5): 055002, 2010 Feb 05.
Article in English | MEDLINE | ID: mdl-20366771

ABSTRACT

The viability of fast-ignition (FI) inertial confinement fusion hinges on the efficient transfer of laser energy to the compressed fuel via multi-MeV electrons. Preformed plasma due to the laser prepulse strongly influences ultraintense laser plasma interactions and hot electron generation in the hollow cone of an FI target. We induced a prepulse and consequent preplasma in copper cone targets and measured the energy deposition zone of the main pulse by imaging the emitted K_{alpha} radiation. Simulation of the radiation hydrodynamics of the preplasma and particle in cell modeling of the main pulse interaction agree well with the measured deposition zones and provide an insight into the energy deposition mechanism and electron distribution. It was demonstrated that a under these conditions a 100 mJ prepulse eliminates the forward going component of approximately 2-4 MeV electrons.

4.
Phys Rev E Stat Nonlin Soft Matter Phys ; 80(4 Pt 2): 045401, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19905383

ABSTRACT

The energy transport in cone-guided low- Z targets has been studied for laser intensities on target of 2.5x10(20) W cm(-2). Extreme ultraviolet (XUV) imaging and transverse optical shadowgraphy of the rear surfaces of slab and cone-slab targets show that the cone geometry strongly influences the observed transport patterns. The XUV intensity showed an average spot size of 65+/-10 microm for slab targets. The cone slabs showed a reduced spot size of 44+/-10 microm. The shadowgraphy for the aforementioned shots demonstrate the same behavior. The transverse size of the expansion pattern was 357+/-32 microm for the slabs and reduced to 210+/-30 microm. A transport model was constructed which showed that the change in transport pattern is due to suppression of refluxing electrons in the material surrounding the cone.


Subject(s)
Energy Transfer/radiation effects , Gases/chemistry , Gases/radiation effects , Hot Temperature , Lasers , Models, Chemical , Computer Simulation
5.
Rev Sci Instrum ; 80(8): 083501, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19725649

ABSTRACT

A dual-channel, curved-crystal spectrograph was designed to measure time-integrated x-ray spectra in the approximately 1.5 to 2 keV range (6.2-8.2 A wavelength) from small-mass, thin-foil targets irradiated by the VULCAN petawatt laser focused up to 4x10(20) W/cm(2). The spectrograph consists of two cylindrically curved potassium-acid-phthalate crystals bent in the meridional plane to increase the spectral range by a factor of approximately 10 compared to a flat crystal. The device acquires single-shot x-ray spectra with good signal-to-background ratios in the hard x-ray background environment of petawatt laser-plasma interactions. The peak spectral energies of the aluminum He(alpha) and Ly(alpha) resonance lines were approximately 1.8 and approximately 1.0 mJ/eV sr (approximately 0.4 and 0.25 J/A sr), respectively, for 220 J, 10 ps laser irradiation.

6.
Rev Sci Instrum ; 79(9): 093507, 2008 Sep.
Article in English | MEDLINE | ID: mdl-19044413

ABSTRACT

Measurements of plasma temperature at the rear surface of foil targets due to heating by hot electrons, which were produced in short pulse high intensity laser matter interactions using the 150 J, 0.5 ps Titan laser, are reported. Extreme ultraviolet (XUV) imaging at 256 and 68 eV energies is used to determine spatially resolved target rear surface temperature patterns by comparing absolute intensities to radiation hydrodynamic modeling. XUV mirrors at these two energies were absolutely calibrated at the Advanced Light Source at the Lawrence Berkeley Laboratory. Temperatures deduced from both imagers are validated against each other within the range of 75-225 eV.

7.
Rev Sci Instrum ; 79(10): 10E305, 2008 Oct.
Article in English | MEDLINE | ID: mdl-19044467

ABSTRACT

A Bremsstrahlung spectrometer using k-edge and differential filtering has been used with image plate dosimeters to measure the x-ray fluence from short-pulse laser/target interactions. An electron spectrometer in front of the Bremsstrahlung spectrometer deflects electrons from the x-ray line of sight and simultaneously measures the electron spectrum. The response functions were modeled with the Monte Carlo code INTEGRATED TIGER SERIES 3.0 and the dosimeters calibrated with radioactive sources. An electron distribution with a slope temperature of 1.3 MeV is inferred from the Bremsstrahlung spectra.

8.
Rev Sci Instrum ; 79(10): 10E312, 2008 Oct.
Article in English | MEDLINE | ID: mdl-19044474

ABSTRACT

Three independent methods (extreme ultraviolet spectroscopy, imaging at 68 and 256 eV) have been used to measure planar target rear surface plasma temperature due to heating by hot electrons. The hot electrons are produced by ultraintense laser-plasma interactions using the 150 J, 0.5 ps Titan laser. Soft x-ray spectroscopy in the 50-400 eV region and imaging at the 68 and 256 eV photon energies give a planar deuterated carbon target rear surface pre-expansion temperature in the 125-150 eV range, with the rear plasma plume averaging a temperature approximately 74 eV.

9.
Rev Sci Instrum ; 79(10): 10F302, 2008 Oct.
Article in English | MEDLINE | ID: mdl-19044615

ABSTRACT

The ignition concept for electron fast ignition inertial confinement fusion requires sufficient energy be transferred from an approximately 20 ps laser pulse to the compressed fuel via approximately MeV electrons. We have assembled a suite of diagnostics to characterize such transfer, simultaneously fielding absolutely calibrated extreme ultraviolet multilayer imagers at 68 and 256 eV; spherically bent crystal imagers at 4.5 and 8 keV; multi-keV crystal spectrometers; MeV x-ray bremmstrahlung, electron and proton spectrometers (along the same line of sight), and a picosecond optical probe interferometer. These diagnostics allow careful measurement of energy transport and deposition during and following the laser-plasma interactions at extremely high intensities in both planar and conical targets. Together with accurate on-shot laser focal spot and prepulse characterization, these measurements are yielding new insights into energy coupling and are providing critical data for validating numerical particle-in-cell (PIC) and hybrid PIC simulation codes in an area crucial for fast ignition and other applications. Novel aspects of these diagnostics and how they are combined to extract quantitative data on ultrahigh intensity laser-plasma interactions are discussed.

10.
Phys Rev Lett ; 100(16): 165002, 2008 Apr 25.
Article in English | MEDLINE | ID: mdl-18518211

ABSTRACT

The heating of solid targets irradiated by 5 x 10(20) W cm(-2), 0.8 ps, 1.05 microm wavelength laser light is studied by x-ray spectroscopy of the K-shell emission from thin layers of Ni, Mo, and V. A surface layer is heated to approximately 5 keV with an axial temperature gradient of 0.6 microm scale length. Images of Ni Ly(alpha) show the hot region has 100 G bar light pressure compresses the preformed plasma and drives a shock into the solid, heating a thin layer.

11.
Rev Sci Instrum ; 79(5): 053501, 2008 May.
Article in English | MEDLINE | ID: mdl-18513063

ABSTRACT

A calibration of three types of GafChromic radiochromic film (HS, MD-55, and HD-810) was carried out on the Crocker Nuclear Laboratory's 76 in. cyclotron at UC Davis over doses ranging from 0.001 to 15 kGy. The film was digitized with a scanning microdensitometer with which it was scanned twice with two different filters to increase the film's effective dynamic range. We demonstrate how this calibrated film can be used to measure the spectrum and total energy of a laser generated proton beam. This technique was applied to an experiment on the 10 J, 100 fs Callisto laser at Lawrence Livermore National Laboratory. The resulting proton spectrum was compared to that obtained by simultaneous measurement of Ti nuclear activation; the two methods give the same proton beam slope temperature and agree in number of protons to within 27%.


Subject(s)
Cyclotrons , Lasers , Protons , X-Ray Film , Calibration
12.
Phys Rev Lett ; 100(1): 015003, 2008 Jan 11.
Article in English | MEDLINE | ID: mdl-18232779

ABSTRACT

Metal foil targets were irradiated with 1 mum wavelength (lambda) laser pulses of 5 ps duration and focused intensities (I) of up to 4x10;{19} W cm;{-2}, giving values of both Ilambda;{2} and pulse duration comparable to those required for fast ignition inertial fusion. The divergence of the electrons accelerated into the target was determined from spatially resolved measurements of x-ray K_{alpha} emission and from transverse probing of the plasma formed on the back of the foils. Comparison of the divergence with other published data shows that it increases with Ilambda;{2} and is independent of pulse duration. Two-dimensional particle-in-cell simulations reproduce these results, indicating that it is a fundamental property of the laser-plasma interaction.

13.
Rev Sci Instrum ; 78(9): 095101, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17902968

ABSTRACT

A novel wide angle spectrometer has been implemented with a highly oriented pyrolytic graphite crystal coupled to an image plate. This spectrometer has allowed us to look at the energy resolved spectrum of scattered x rays from a dense plasma over a wide range of angles (approximately 30 degrees ) in a single shot. Using this spectrometer we were able to observe the temporal evolution of the angular scatter cross section from a laser shocked foil. A spectrometer of this type may also be useful in investigations of x-ray line transfer from laser-plasmas experiments.

14.
J Inherit Metab Dis ; 21(1): 49-59, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9501269

ABSTRACT

Gaucher disease is a lysosomal storage disease characterized by storage of glucocerebroside due to lysosomal glucocerebrosidase deficiency. Increased urinary excretion of sialyloligosaccharides and mannosylglycoasparagines has been described for two patients with the infantile form of the disease, probably as a consequence of obstruction of lysosomal functioning due to the glycolipid accumulation in lysosomes. By thin-layer chromatography, we found increased urinary oligosaccharide excretion in a series of adult non-neuronopathic patients. Oligosaccharide patterns were comparable between patients and also with the pattern observed in infantile Gaucher disease. Composition was analysed by methanolysis and gas chromatography. Mannose and N-acetylglucosamine are the main carbohydrates in all oligosaccharide bands. A statistically significant correlation was found between oligosaccharide excretion and the severity of the disease expressed as severity score index. Patients treated with enzyme replacement therapy showed a reduction up to 65% of the original oligosaccharide excretion after 1 year of treatment, comparable with the reduction in spleen volume.


Subject(s)
Gaucher Disease/metabolism , Oligosaccharides/metabolism , Adult , Carbohydrates/analysis , Chromatography, Thin Layer , Gaucher Disease/drug therapy , Gaucher Disease/physiopathology , Glucosylceramidase/therapeutic use , Humans , Severity of Illness Index
15.
Opt Lett ; 21(16): 1286-8, 1996 Aug 15.
Article in English | MEDLINE | ID: mdl-19876327

ABSTRACT

We have developed a novel method of time-of-f light (TOF) photoelectron spectroscopy that permits observation of multiphoton ionizations with extremely high precision, especially for low-probability events. By scanning the laser-produced ionization region across a pinhole we can select specific laser peak intensities. The volumes occupied by low intensities rise rapidly compared with traditional straight TOF spectroscopy, resulting in high signal gains. This technique presents a new way of observing fundamental laser-matter interactions.

16.
Opt Lett ; 17(15): 1067-9, 1992 Aug 01.
Article in English | MEDLINE | ID: mdl-19794721

ABSTRACT

We have developed a combined Ti:Al(2)O(3)/Cr:LiSrAlF(6) laser system capable of producing terawatt pulses with a duration of 120 fs at a 1-Hz repetition rate. Chirped-pulse amplification in Ti:sapphire produces compressed 45-mJ pulses. Further amplification in flash-lamp-pumped Cr:LiSrAlF(6) produces 150-mJ compressed pulses with no significant effect on beam quality or pulse shape.

17.
Clin Chim Acta ; 143(3): 193-201, 1984 Nov 30.
Article in English | MEDLINE | ID: mdl-6499218

ABSTRACT

Total CK activity is often increased in cerebrospinal fluid samples in neurological diseases (35%). These increased levels are frequently caused by CK M-chain activity and appear to have no diagnostic relevance. Furthermore, an obvious concentration gradient for total CK activity was often observed in two subsequent tubes from the same lumbar puncture. In this study, CK non-M activity is measured, being the sum of all CK activity not caused by the M-chain. A bioluminescence technique using anti-M-inhibiting antibodies was used for this purpose. In two subsequent tubes from the same lumbar puncture a difference of 8% in CK non-M activity was found. A similar gradient could be observed for total protein. Retrospectively, the correlation between CK non-M levels and the amount of brain tissue damage was studied in 81 neurological patients and in 19 healthy subjects. There was an obvious relation between the extent of brain tissue damage and the CSF CK non-M levels. The clinical results in this study are promising and justify a prospective study of the diagnostic relevance of this parameter in CSF in various patient groups.


Subject(s)
Brain Diseases/enzymology , Creatine Kinase/cerebrospinal fluid , Brain Diseases/etiology , Brain Diseases/pathology , Humans , Isoenzymes , Reference Values , Retrospective Studies
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