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1.
Afr J Prim Health Care Fam Med ; 7(1): 892, 2015 Dec 17.
Article in English | MEDLINE | ID: mdl-26842523

ABSTRACT

BACKGROUND: Interventions by community care workers within the context of community-based integrated management of childhood illness (CIMCI) may have a positive effect on child health if the health workers have adequate knowledge about key family practices. SETTING: The study was conducted in rural areas of the West Coast district in the Western Cape, South Africa. OBJECTIVES: The objective of this study was to determine the knowledge of community care workers about five of the 16 key family practices of CIMCI. METHODS: A descriptive survey collected a self-administered questionnaire from 257 community care workers out of a possible total of 270 (95.2% response rate). Descriptive and inferential statistical analysis was applied. RESULTS: Only 25 of the respondents (10%) obtained a score higher than 70% on the knowledge-based items of the questionnaire. Less than 25% of respondents answered questions in these key areas correctly (pneumonia [17%], tuberculosis [13%], HIV/AIDS [9%] immunisation [3%] and recommendations for a child with fever [21%]). Statistically significant correlations were found between the total score a respondent achieved and the highest level of education obtained (p < 0.01), the level of in-service training (p < 0.01), attendance of a CIMCI five-day training course (p < 0.01), and completing a subsequent refresher course (p < 0.01). CONCLUSION: The knowledge of CCWs was inadequate to provide safe, quality CIMCI. CIMCI refresher courses should be offered annually to improve CCWs' knowledge and the quality of care that they render. Regular update courses could contribute to building competence.


Subject(s)
Community Health Workers/psychology , Family Practice , Health Knowledge, Attitudes, Practice , Rural Population , Adult , Child Health , Female , Humans , Male , Surveys and Questionnaires
2.
Viruses ; 6(8): 2991-3018, 2014 Aug 07.
Article in English | MEDLINE | ID: mdl-25105276

ABSTRACT

The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly. Recent studies have confirmed that N is a multifunctional protein. The aim of this review is to highlight the properties and functions of the N protein, with specific reference to (i) the topology; (ii) the intracellular localization and (iii) the functions of the protein.


Subject(s)
Coronavirus/physiology , Nucleocapsid Proteins/metabolism , Virus Replication , Coronavirus Nucleocapsid Proteins , Protein Transport
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