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1.
Arch Dermatol Res ; 312(10): 715-724, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32166376

ABSTRACT

Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Dermatologic Surgical Procedures , Hidradenitis Suppurativa/therapy , Obesity/epidemiology , Smoking/epidemiology , Acne Vulgaris/epidemiology , Administration, Cutaneous , Administration, Oral , Adolescent , Body Mass Index , Child , Clindamycin/administration & dosage , Comorbidity , Cross-Sectional Studies , Drug Therapy, Combination/methods , Female , Hidradenitis Suppurativa/epidemiology , Hirsutism/epidemiology , Humans , Male , Pilonidal Sinus/epidemiology , Resorcinols/administration & dosage , Rifampin/administration & dosage , Risk Factors , Severity of Illness Index , Tetracycline/administration & dosage , Treatment Outcome , Young Adult
2.
Int J Surg Pathol ; 28(5): 514-516, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32054364

ABSTRACT

Cutaneous lymphomas are encountered infrequently in general surgical pathology practice, and the broad array of pathological entities poses a diagnostic challenge. Integration of clinical information, results of additional laboratory investigations, and an extensive immunohistochemical panel are essential in arriving at the correct diagnosis. We present a case of blastic plasmacytoid dendritic cell neoplasm that occurred in an unusual clinical setting. This case highlights the need for a broad differential diagnosis and an extensive immunohistochemical workup when approaching a cutaneous lymphoma.


Subject(s)
Dendritic Cells/pathology , Lymphoma/diagnosis , Lymphoma/pathology , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , Diagnosis, Differential , Female , Humans , Young Adult
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