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1.
Ned Tijdschr Tandheelkd ; 117(4): 215-8, 2010 Apr.
Article in Dutch | MEDLINE | ID: mdl-20446550

ABSTRACT

A 21-year-old woman was referred by the dental practitioner to an oral surgeon concerning a hard elastic swelling of the left cheek in combination with local paresthesia. Histopathologic and radiographic examination revealed an osteosarcoma in the left segment of the maxilla. Subsequently, the patient was referred to a medical centre for head and neck oncology. The treatment consisted of 3 courses neoadjuvant chemotherapy, followed by radical surgical resection of the tumor, and 3 courses adjuvant chemotherapy. One year after treatment, there was no sign of local tumor recurrence or metastases. An osteosarcoma is a malignant tumor of bone forming cells. About 10% of osteosarcomas are appearing in the head and neck region, primarily in the mandible and the maxilla. The treatment of choice is adequate surgical removal. Treatment with (neo)adjuvant chemotherapy seems to have additional benefit, but this needs further research.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols , Maxillary Neoplasms/diagnosis , Osteosarcoma/diagnosis , Chemotherapy, Adjuvant , Combined Modality Therapy , Female , Humans , Maxillary Neoplasms/drug therapy , Maxillary Neoplasms/surgery , Osteosarcoma/drug therapy , Osteosarcoma/surgery , Treatment Outcome , Young Adult
2.
Int J Oral Maxillofac Surg ; 37(7): 630-3, 2008 Jul.
Article in English | MEDLINE | ID: mdl-18538542

ABSTRACT

Oral lichen planus is a relatively common disease of the oral mucosa. The buccal mucosa and lateral border of the tongue are mostly involved, although the condition can occur anywhere in the oral cavity. The erosive type in particular can cause spontaneous pain during eating. In the period from 1975 to 2003, a group of 21 patients with 39 lesions of oral lichen planus which caused pain, even after conservative therapy, were treated with CO2 laser evaporation. During a follow-up period of 1-18 years (mean 8 years) 21 patients were pain free (85%) and 6 patients (15%) experienced painful recurrence after treatment. After retreatment with CO2 laser evaporation there were no complaints of pain. Among the many treatments available, high-potency topical corticosteroids remain the most consistent and effective. In patients whose condition is unresponsive to topical corticosteroids, CO2 laser evaporation can cause long-term remission of symptoms, and may even be the treatment of first choice in patients suffering from painful oral lichen planus.


Subject(s)
Laser Therapy , Lasers, Gas/therapeutic use , Lichen Planus, Oral/surgery , Adult , Female , Fluocinonide/therapeutic use , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Male , Middle Aged , Mouth Mucosa/surgery , Pain/surgery , Recurrence , Retreatment , Retrospective Studies , Tongue Diseases/surgery , Triamcinolone/therapeutic use
3.
Oral Oncol ; 41(1): 31-7, 2005 Jan.
Article in English | MEDLINE | ID: mdl-15598583

ABSTRACT

Oral leukoplakia is an important premalignant lesion of the oral mucosa. We treat this lesion prophylactically with CO2 laser evaporation. In the period from 1976 to 2001, a group of 200 patients with 282 oral leukoplakias were treated by CO2 laser evaporation. In a follow up period of 1-219 months (mean 52), 251 treated leukoplakias (89.0%) did not show a recurrence. Twenty eight (9.9%) local recurrences were observed in 5 to 168 months after treatment. Three (1.1%) squamous cell carcinoma, occurred in the treated area respectively 7, 17 and 19 month after CO2 laser evaporation. This large study with a long follow up shows that laser treatment is a good prophylactic treatment for oral leukoplakia.


Subject(s)
Laser Therapy/methods , Leukoplakia, Oral/surgery , Adult , Age Distribution , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/prevention & control , Cell Transformation, Neoplastic , Female , Follow-Up Studies , Humans , Laser Therapy/instrumentation , Leukoplakia, Oral/pathology , Male , Middle Aged , Mouth Neoplasms/prevention & control , Recurrence , Sex Distribution , Wound Healing
4.
Ned Tijdschr Tandheelkd ; 97(10): 433-4, 1990 Oct.
Article in Dutch | MEDLINE | ID: mdl-2130266

ABSTRACT

This article presents the results of an enquiry by telephone of the attainableness and availability of dentists during weekend duty. In 89.5% of the cases a patient can be treated by a dentist he phoned or his substitute within a reasonable period of time. In 10.5% a patient does not obtain a satisfactory solution after telephoning a dentist once.


Subject(s)
Appointments and Schedules , Continuity of Patient Care , Dentists , Emergencies , Holidays , Night Care
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