1.
J Reticuloendothel Soc
; 21(4): 237-44, 1977 Apr.
Article
in English
| MEDLINE
| ID: mdl-195052
Subject(s)
Blood Platelets/drug effects , Cyclophosphamide/pharmacology , Neutrophils/drug effects , Blood Glucose/metabolism , Blood Platelets/metabolism , Blood Proteins/biosynthesis , Cells, Cultured , Cyclic AMP/blood , Glycogen/blood , Humans , Neutrophils/metabolism , Nitroblue Tetrazolium/blood , Oxidation-Reduction , Phagocytosis , RNA/blood
2.
Scand J Haematol
; 15(4): 261-71, 1975 Nov.
Article
in English
| MEDLINE
| ID: mdl-1198065
ABSTRACT
A patient with clinical and haematological findings compatible with congenital dyserythropoietic anaemia (CDA) most porbably type II is described. In contradistinction to previous observations, electron microscope examination of the erythroid cells in the bone marrow showed the concomitant appearance of nuclei at different maturation stages in a single cell. In addition, a marked tendency toward multinuclearity of the megakaryocytes was found. The mature erythroblasts showed an increased uptake of 3H-thymidine less than is normally found in these cells. Thes findings suggest an impairment in RNA and DNA synthesis.
Subject(s)
Anemia/congenital , Cell Nucleus/ultrastructure , Erythroblasts/ultrastructure , Erythrocytes/ultrastructure , Erythropoiesis , Adult , Anemia/blood , Anemia/pathology , Basophils/ultrastructure , Biopsy, Needle , Bone Marrow/ultrastructure , Bone Marrow Cells , Cytoplasm/ultrastructure , Erythroblasts/metabolism , Humans , Male , Megakaryocytes/ultrastructure , Microscopy, Electron , Thymidine/blood , Uridine/blood
3.
Scand J Haematol
; 12(2): 104-11, 1974.
Article
in English
| MEDLINE
| ID: mdl-4275399