Subject(s)
Fatty Acids/analysis , Keloid/pathology , Lipids/analysis , Cell Hypoxia , Chromatography, Thin Layer , Fibroblasts/metabolism , Fibroblasts/pathology , Humans , Keloid/metabolism , Linoleic Acid/analysis , Membrane Lipids/analysis , Microcirculation , Phospholipids/analysis , Wound HealingSubject(s)
Carcinoma, Basal Cell/chemistry , Carcinoma, Basal Cell/pathology , Carcinoma, Squamous Cell/chemistry , Carcinoma, Squamous Cell/pathology , Linoleic Acid/analysis , Skin Neoplasms/chemistry , Skin Neoplasms/pathology , Adult , Carcinoma in Situ/chemistry , Carcinoma in Situ/pathology , Cell Cycle , Cell Division , Humans , Mitosis , Neoplasm Invasiveness , Predictive Value of Tests , Sensitivity and SpecificityABSTRACT
The total fatty acid compositions of neoplastic tissues in 5 different meningioma types (meningotheliomatous, transitional, vascular, fibroblastic, atypical), analysed by gas-liquid chromatography, are presented in correlation with their histopathology. The benign meningioma types (first 3) had higher relative percentages of linoleic acid, compared to the apparently malignant meningioma types (fibroblastic, atypical). From these results it is suggested that a high relative percentage of linoleic acid is characteristic of benign neoplastic growth, while a low relative percentage may correlate with increased malignancy.
Subject(s)
Linoleic Acids/analysis , Meningeal Neoplasms/pathology , Meningioma/pathology , Biomarkers/analysis , Humans , Linoleic Acid , Meningeal Neoplasms/chemistry , Meningeal Neoplasms/classification , Meningioma/chemistry , Meningioma/classification , Prospective StudiesABSTRACT
The cellular long-chain fatty acids present in 33 strains, representing 15 species of Cryptococcus, and 4 species of Tremella, were determined by gas chromatography. According to the relative amounts of fatty acid methyl esters, the Cryptococcus species studied were divided into four main groups. Possible relationships between species representing the two genera are presented in a new model, where cellular long-chain fatty acid compositions and other phenotypic characteristics are included.
