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Muscle Nerve ; 52(3): 380-5, 2015 Sep.
Article in English | MEDLINE | ID: mdl-25522919

ABSTRACT

INTRODUCTION: We conducted a randomized, double-blind, placebo-controlled trial to evaluate the effect of ultrasound-guided corticosteroid injection in patients with ulnar neuropathy at the elbow (UNE). METHODS: Fifty-five patients were randomized between an ultrasound-guided injection of 1 ml containing 40 mg methylprednisolone acetate and 10 mg lidocaine hydrochloride or a placebo injection. The primary outcome was the subjective change of symptoms after 3 months. The secondary outcomes were change in electrodiagnostic studies and ultrasonography findings. RESULTS: A success rate of 30% was found in the corticosteroid injection group versus 28% in the placebo injection group. Only the nerve cross-sectional area changed significantly in the intervention group, from a mean of 11.9 mm(2) to 10.9 mm(2) . CONCLUSIONS: We could not demonstrate a positive effect of ultrasound-guided corticosteroid injection in UNE compared with placebo. Favorable outcomes may be attributed to the natural course of UNE or the effect of patient education.


Subject(s)
Anti-Inflammatory Agents/therapeutic use , Cubital Tunnel Syndrome/drug therapy , Methylprednisolone/analogs & derivatives , Adrenal Cortex Hormones/therapeutic use , Adult , Aged , Aged, 80 and over , Anesthetics, Local/therapeutic use , Cubital Tunnel Syndrome/diagnostic imaging , Double-Blind Method , Elbow , Female , Humans , Injections , Lidocaine , Male , Methylprednisolone/therapeutic use , Methylprednisolone Acetate , Middle Aged , Treatment Outcome , Ulnar Neuropathies/diagnostic imaging , Ulnar Neuropathies/drug therapy , Ultrasonography, Interventional , Young Adult
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