Exploring the potential of omics technologies in medicinal plant research: a review in Colombia / Explorando el potencial de las tecnologías ómicas en la investigación de plantas medicinales: una revisión en Colombia

This review presents advances in the implementation of high - throughput se quencing and its application to the knowledge of medicinal plants. We conducted a bibliographic search of papers published in PubMed, Science Direct, Google Scholar, Scopus, and Web of Science databases and analyzed the obtained data using VOSviewer (versi on 1.6.19). Given that medicinal plants are a source of specialized metabolites with immense therapeutic values and important pharmacological properties, plant researchers around the world have turned their attention toward them and have begun to examine t hem widely. Recent advances in sequencing technologies have reduced cost and time demands and accelerated medicinal plant research. Such research leverages full genome sequencing, as well as RNA (ribonucleic acid) sequencing and the analysis of the transcr iptome, to identify molecular markers of species and functional genes that control key biological traits, as well as to understand the biosynthetic pathways of bioactive metabolites and regulatory mechanisms of environmental responses. As such, the omics ( e.g., transcriptomics, metabolomics, proteomics, and genomics, among others) have been widely applied within the study of medicinal plants, although their usage in Colombia is still few and, in some areas, scarce. (185)

El extracto de cloroformo (CE) y las fracciones obtenidas de las raíces de Aldama arenaria se evaluaron para determinar su actividad antiproliferativa in vitro contra 10 líneas ce lulares tumorales humanas [leucemia (K - 562), mama (MCF - 7), ovario que expresa un fenotipo resistente a múltiples fármacos (NCI/ADR - RES), melanoma (UACC - 62), pulmón (NCI - H460), próstata (PC - 3), colon (HT29), ovario (OVCAR - 3), glioma (U251) y riñón (786 - 0)]. CE presentó actividad antiproliferativa débil a moderada (log GI 50 medio 1.07), mientras que las fracciones 3 y 4, enriquecidas con diterpenos de tipo pimarane [ent - pimara - 8 (14), ácido 15 - dien - 19 - oico y ent - 8(14),15 - pimaradien - 3 ß - ol], presentaron activid ad moderada a potente para la mayoría de las líneas celulares, con un log GI 50 medio de 0.62 y 0.59, respectivamente. Los resultados mostraron una acción antiproliferativa in vitro prometedora de las muestras obtenidas de A. arenaria , con los mejores resul tados para NCI/ADR - RES, HT29 y OVCAR - 3, y valores de TGI que van desde 5.95 a 28.71 µg.mL - 1, demostrando que los compuestos de esta clase pueden ser prototipos potenciales para el descubrimiento de nuevos agentes terapéuticos

Chemical composition, antioxidant and antimicrobial activities of essential oil from the aerial parts of Chuquiraga arcuataHarling grown in the highlands of Ecuador / Composición química, actividades antioxidantes y antimicrobianas del aceite esencial de las partes aéreas de Chuquiraga arcuataHarling cultivado en las tierras altas del Ecuador

Thechemical composition, antioxidant and antimicrobial activities of the essential oil from aerial parts (leaves and flowers) of Chuquiraga arcuataHarling grown in the Ecuadorian Andes were studied. One hundred and twenty-six compounds were identified in the essential oil. Monoterpene hydrocarbons (45.8%) and oxygenated monoterpenes (44.1%) had the major percentages. The most abundant compounds were camphor (21.6%), myrcene (19.5%), and 1,8-cineole (13.4%). Antioxidant activity was examined using DPPH, ABTS,and FRAP assays. The essential oil had a moderate scavenging effect and reduction of ferric ion capacity through FRAP assay. Antimicrobial activity of the essential oil was observed against four pathogenic bacteria and a fungus. The essential oil exhibited activity against all microorganism strains under test, particularly against Candida albicansand Staphylococcus aureuswith MICs of 2.43-12.10 µg/mL.

Se estudió la composición química, actividades antioxidantes y antimicrobianas del aceite esencial procedente de las partes aérea (hojas y flores) de Chuquiraga arcuataHarling cultivadas en los Andes ecuatorianos. Se identificaron 126 compuestos en el aceite esencial. Los hidrocarburos monoterpénicos (45,8%) y los monoterpenos oxigenados (44,1%) tuvieron el mayor porcentaje. Los compuestos más abundantes fueron alcanfor (21,6%), mirceno (19,5%) y 1,8-cineol (13,4%). La actividadantioxidante se examinó mediante ensayos DPPH, ABTS y FRAP. El aceite esencial tuvo un efecto eliminador moderado y una reducción de la capacidad de iones férricos mediante el ensayo FRAP. Se observó actividad antimicrobiana del aceite esencial contra cuatro bacterias y un hongo patógenos. El aceite esencial mostró actividad contra todas las cepas de microorganismos bajo prueba, particularmente contra Candida albicansy Staphylococcus aureuscon CMI de 2,43-12,10 µg/mL.

Exactitud del Xiaomi Mi Band 4 para contabilizar pasos en adultos con enfermedades respiratorias crónicas. Estudio de concordancia / Accuracy of the Xiaomi Mi Band 4 for Steps Counting in Adults with Chronic Respiratory Diseases. Agreement Study

Introducción: El Xiaomi Mi Band 4 (XMB4) demostró ser exacto para medir pasos en sujetos sanos, pero no ha sido estudiado en pacientes con enfermedades respiratorias crónicas (ERC). Objetivos: Evaluar la exactitud del XMB4 para cuantificar pasos caminados en pacientes con ERC. Secundariamente, evaluar su viabilidad y usabilidad.Material y métodos: Estudio de concordancia contrastando los datos del XMB4 con la video-filmación (prueba de referencia). Fueron incluidos mayores de 18 años con diversas ERC y excluidos aquellos con deterioro cognitivo, limitaciones osteoarticulares y/o cardiovasculares que impedían la marcha. Realizamos un muestreo por conveniencia de pacientes que participaban de un programa de rehabilitación pulmonar.Las variables estudiadas incluyeron número de pasos, distancia y tiempo caminado, velocidad de la marcha, viabilidad y usabilidad. Cada participante realizó cinco caminatas (5, 10 y 30 metros, y 5 minutos a ritmo lento y rápido). Para testear la equivalencia estadística, necesitamos incluir 33 pacientes y utilizamos el método de intervalo de confianza con una zona de equivalencia de ±15%. Resultados: Fueron incluidos 33 pacientes, 64% mujeres, con una mediana (P25-75) de edad de 64,9 (55,8 a 70,2) años. Los pasos registrados por el XMB4 fueron equivalentes a los de la video-filmación en las diferentes caminatas, excepto en la de 5 metros. Los pasos fueron subestimados con un error de medición menor al 15%. Conclusiones: El XMB4 tiene una exactitud aceptable para medir pasos en pacientes con ERC excepto en caminatas muy cortas, es viable y fácil de usar

Introduction: Xiaomi Mi Band 4 (XMB4) has been shown to be accurate to measure steps in healthy subjects, but has not been studied in patients with chronic respiratory diseases (CRD).Objectives: To evaluate the accuracy of the XMB4 to quantify steps walked in patients with CRD. Secondarily, evaluate its feasibility and usability.Materials and methods: Agreement study compared the XMB4 data with the video (reference test). Adults aged 18 years or older with various CRD were included and those with cognitive impairment, osteoarticular and/or cardiovascular limitations that prevented walking were excluded. We conducted a convenience sampling of patients participating in a pulmonary rehabilitation program. Outcome measures studied included number of steps, distance and time walked, walking speed, feasibility and usability. Each participant performed five walks (5, 10 and 30 meters, and 5 minutes at a slow and fast pace).To test statistical equivalence we need to include 33 patients and use the confidence interval method with an equivalence zone of ±15%.Results: 33 patients were included, 64% women, with a median (P25-75) age of 64.9 (55.8 to 70.2) years. The steps recorded by the XMB4 were equivalent to those of the video in the different walks, except for the 5-meter walk. The steps were underestimated with a measurement error of less than 15%.Conclusions: XMB4 has acceptable accuracy for measuring steps in patients with CRD except for very short walks, it is feasible and easy to us.

Measurement assessment of Minimal Disease Activity in psoriasis in Spain: a national cross-sectional study. / Valoración de la medida de Actividad Mínima de Enfermedad en Psoriasis en España: estudio transversal nacional.

INTRODUCTION: in 2017, the Spanish Academy of Dermatology and Venereology Psoriasis Working Group (PWG) designed the Minimal Disease Activity (MDA) criteria to determine the level of disease activity. We hereby present the results of an observational, cross-sectional, multicenter study of the nationwide application of these criteria. MATERIAL AND METHODS: we conducted a non-randomized sampling, stratified to achieve autonomic and provincial representation of consecutive patients with psoriasis (Ps) vulgaris without active arthritis. A total of 830 patients were included: 493 men (59.5%), with a mean age of 51.4 years (SD, 14.2), from all autonomous regions of Spain (except for Ceuta and Melilla) and 44 (88%) out of the 50 provinces. A questionnaire was obtained with demographic data, DLQI, subjective assessment-on a scale from 0 to 10-of itching, erythema, desquamation, visibility, and the patients' PASI and BSA. RESULTS: more than 50% failed to meet the MDA criteria (491; 59.2%), with significant differences being reported by region, sex, and age. Additionally, significant differences were reported based on the therapy used (p < 0.001). The use of biological therapies was associated with higher MDA compliance compared to other therapies (59.4% vs 23.3%). No differences were reported among various biological therapies. CONCLUSIONS: the overall rate of MDA compliance is low, with differences being based on geographic location, sex, age, and drug used, yet none of these factors separately justify them.

[Prevalence of physical inactivity and risk of sarcopenia in primary care. Cross-sectional study]. / Prevalencia de inactividad física y riesgo de sarcopenia en atención primaria. Estudio transversal.

OBJECTIVES: Assess the prevalence of physical inactivity and risk of sarcopenia in primary care patients and their companions. DESIGN: Cross-sectional study. We carried out an anonymous survey of primary care users (patients and companions) in primary care consultations and stands coinciding with a community health activity for World Physical Activity Day. SITE: Five primary care centers (CAPs) of the South Metropolitan health region: in Cornellà de Llobregat (CAP Jaume Soler), in l'Hospitalet de Llobregat (CAP Florida Nord, CAP Florida Sud and CAP Bellvitge) and in Viladecans (CAP Maria Bernades) between 27 March to April 6, 2023 (coinciding with World Physical Activity Day). PARTICIPANTS: Primary care population consists of patients and their companions over 18 years of age. INTERVENTIONS: The health workers administered questionnaires to users and companions. MAIN MEASUREMENTS: We evaluated physical inactivity with the BPAAT questionnaire, risk of sarcopenia with SARC-F screening test, sex and age range. We performed an univariate descriptive analysis to report prevalence. RESULTS: Nine hundred ninety-eight participants were surveyed. Physical inactivity was present in 38.9% of the participants. Among those over 50 years (665 participants), 15.4% were at risk of sarcopenia (9.58% men, 19.2% women). CONCLUSIONS: The prevalence of physical inactivity and risk of sarcopenia (in individuals over 50 years old) in the studied population is high. Women have greater physical inactivity and a greater risk of sarcopenia than men.

Profiling the patient with inflammatory bowel disease in the relationship between physical activity and partner/social network status: A post hoc patient-tailored analysis of the "BE-FIT-IBD" study.

INTRODUCTION: Normal quality of life is an ultimate target in the therapeutic approach to inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC) in the context of which regular physical activity (PA) is often a chimeric parameter that is not standardized in terms of quality/quantity. The study aimed to profile a sample of IBD patients about the relationship between PA-partner status and social network support. PATIENTS AND METHODS: A post hoc analysis of the "BE-FIT-IBD" study was set up by stratifying the data of PA with that of partner status and the support that the patient's social network (i.e., relatives, friends) provided in inciting the patient to practice regular PA. RESULTS: In the 219 patients included, there was a greater tendency for patients with stable partners to view the risk of reactivation/worsening of IBD as a barrier to conducting regular PA (p<0.0001). Single patients considered PA more as a protective factor (p=0.045). Patients without a PA-supporting social network retained IBD-related treatment as a PA barrier (p=0.016) and PA as a risk for IBD complications (p=0.01), with less confidence that PA could improve the course of IBD (p<0.001). Rectal syndrome was an IBD-related barrier more represented in patients with PA-deterring social network (p<0.0001). CONCLUSIONS: These factors are potential targets for recovering the IBD patient's adherence to regular PA.

Levels of sCD163 in women rheumatoid arthritis: Relationship with cardiovascular risk markers.

AIM: The soluble scavenger receptor differentiation antigen 163 (sCD163), a monocyte/macrophage activation marker, is related to cardiovascular mortality in the general population. This study aimed to evaluate their relationship between serum levels of sCD163 with cardiovascular risk indicators in rheumatoid arthritis (RA). METHODS: A cross-sectional study was performed on 80 women diagnosed with RA. The cardiovascular risks were determined using the lipid profile, metabolic syndrome, and QRISK3 calculator. For the assessment of RA activity, we evaluated the DAS28 with erythrocyte sedimentation rate (DAS28-ESR). The serum levels of sCD163 were determined by the ELISA method. Logistic regression models and receiver operating characteristics (ROC) curve were used to assess the association and predictive value of sCD163 with cardiovascular risk in RA patients. RESULTS: Levels of sCD163 were significantly higher in RA patients with high sensitivity protein C-reactive to HDL-c ratio (CHR)≥0.121 (p=0.003), total cholesterol/HDL-c ratio>7% (p=0.004), LDL-c/HDL-c ratio>3% (p=0.035), atherogenic index of plasma>0.21 (p=0.004), cardiometabolic index (CMI)≥1.70 (p=0.005), and high DAS28-ESR (p=0.004). In multivariate analysis, levels of sCD163≥1107.3ng/mL were associated with CHR≥0.121 (OR=3.43, p=0.020), CMI≥1.70 (OR=4.25, p=0.005), total cholesterol/HDL-c ratio>7% (OR=6.63, p=0.044), as well as with DAS28-ESR>3.2 (OR=8.10, p=0.008). Moreover, levels of sCD163 predicted CHR≥0.121 (AUC=0.701), cholesterol total/HDL ratio>7% (AUC=0.764), and DAS28-ESR>3.2 (AUC=0.720). CONCLUSION: Serum levels of sCD163 could be considered a surrogate of cardiovascular risk and clinical activity in RA.

[Self-sense and experiences of physical activity in breast cancer survivors: Qualitative evidence synthesis]. / Significados y experiencias de actividad física en mujeres sobrevivientes de cáncer de mama: síntesis cualitativa.

Breast cancer has a high incidence rate and a negative impact on women's lives. The practice of physical activity (PA) has shown strong evidence in controlling the side effects associated with the disease and its treatment. However, having an active lifestyle is influenced by socio-health inequities. The objective was to analyze the categories related to the meanings and perceived experiences with PA in breast cancer survivors (BCS). Protocol https://osf.io/7fwbs/. Articles describing the meanings of PA in BCS published after 2010 were included. Fourteen articles were analyzed using line-by-line coding. The emerging categories were: 1)PA as a strategy to re-signify and empower the body. 2)Cancer means a change in PA trajectories. 3)PA is a tool for a healthy and functional body in everyday life.

[What needs do experts and future Physical Activity and Sport professionals perceive to promote healthy aging? Professionals and students' views]. / ¿Qué necesidades perciben los expertos y los futuros profesionales de la Actividad Física y del Deporte para promover un envejecimiento saludable? Visión de profesionales y estudiantes.

INTRODUCTION: Physical activity acts as an adjuvant in the treatment of numerous diseases and in the promotion of healthy aging. Increasing longevity entails an increase in the demand for professionals who prescribe physical activity, specifically physiotherapists and physical-activity educators. OBJECTIVES: The main objective of this study was to explore the perceptions of a group of third- and fourth-year Physiotherapy students (n=9) and Sport Sciences students (n=5), and experts who work with older adults (n=3) about their knowledge of the older adult population and healthy aging. The secondary objectives were to: (a) explore what knowledge future professionals need about physical activity programming and about physical activity programs aimed at maintaining and improving health among older adults; (b) explore what would be the best methodology to acquire such knowledge; and (c) explore whether a relationship is perceived between knowledge about the older adult population and motivation to work with this population group. METHODS: Two discussion groups with students and three interviews with experts were conducted. Discussion groups and interviews were transcribed verbatim and analyzed through a reflexive thematic analysis, following the steps described by Braun and Clarke (2021). RESULTS: Three themes were identified from the discussion groups: (1) conception and ideas about older adults, (2) skills and knowledge perceived as important, and (3) proposals for motivational intervention addressed to the older population. Four themes were identified from the interviews with experts: (1) characteristics of the future professional, (2) physical activity programs for older people: the recipe for success, (3) the role of enjoyment as key to success, and (4) barriers/obstacles along the path. CONCLUSION: Students of both degrees and experts believe that more practical training opportunities are needed, to enable students to interact with the older population and get to know their needs, motivations, and barriers, to increase physical activity levels in this population group.

Promoción de actividades físicas para adultos mayores: Una estrategia educativa para estudiantes de Gerontología

En la actualidad, existe una tendencia progresiva al envejecimiento de la población. El propósito de esta investigación consistió exponer una estrategia educativa para los estudiantes del 5.º nivel de Gerontología que contribuya a la promoción de la actividad física en el adulto mayor. La investigación se enmarcó en una metodología mixta y un diseño descriptivo de corte transversal. Se emplearon métodos científicos que en el orden teórico se encuentran análisis-síntesis, inductivo-deductivo y el sistémico estructural, y como métodos empíricos la revisión documental, la observación, la encuesta y entrevistas, las cuales fueron aplicadas a una muestra de 38 sujetos y revelan la importancia de la actividad física como estrategia que permite alcanzar un envejecimiento activo y con calidad de vida en la tercera edad. Según estos resultados, la aplicación de una estrategia educativa estructurada en tres etapas y dos fases contribuye a la autogestión del aprendizaje de los estudiantes, donde el contexto profesional se convierte en un auténtico espacio de formación.

Atualmente, há uma tendência progressiva de envelhecimento da população. O objetivo desta pesquisa foi apresentar uma estratégia educacional para estudantes do 5º nível de Gerontologia que contribua para a promoção da atividade física em idosos. A pesquisa foi enquadrada em uma metodologia mista e um desenho descritivo transversal. Foram utilizados os métodos científicos teórico, indutivo-dedutivo e sistêmico-estrutural, e os métodos empíricos foram revisão documental, observação, inquérito e entrevistas, que foram aplicados a uma amostra de 38 sujeitos e revelam a importância da atividade física como estratégia para alcançar o envelhecimento ativo e a qualidade de vida dos idosos. De acordo com esses resultados, a aplicação de uma estratégia educacional estruturada em três etapas e duas fases contribui para o autogerenciamento da aprendizagem dos alunos, em que o contexto profissional se torna um autêntico espaço de treinamento.

Currently, there is a progressive trend towards population aging. The purpose of this research was to present an educational strategy for students of the 5th level of Gerontology that contributes to the promotion of physical activity in older adults. The research was framed in a mixed methodology and a cross-sectional descriptive design. Scientific methods were used that in the theoretical order include analysis-synthesis, inductive-deductive and structural systemic and as empirical methods documentary review, observation, survey and interviews, applied to a sample of 38 subjects. The study revealed the importance of physical activity as a strategy that allows achieving active aging with quality of life. According to these results, the application of an educational strategy, structured in three stages and two phases, contributes to the self-management of student learning, where the professional context becomes an authentic training space.

A perspectiva do adolescente sobre atividade física e saúde mental durante a pandemia da covid-19 / Teenager perspective on physical activity and health mental during the COVID-19 pandemic / La perspectiva del adolescente sobre la actividad física y la salud mental durante la pandemia del COVID-19

Em 11 de março de 2020, a Organização Mundial de Saúde declarou que a epidemia da covid-19 evoluiu para uma pandemia. As medidas de isolamento tomadas diante do cenário pandêmico provocaram impactos diretos na vida e na saúde física e mental da população. O objetivo deste estudo foi investigar a perspectiva do adolescente em relação à prática de atividade física e à saúde mental durante a pandemia da covid-19. Trata-se de um estudo descritivo de abordagem qualitativa, seguindo um roteiro semiestruturado, com 11 adolescentes de 11 a 19 anos de idade em acompanhamento com a equipe Residência Multiprofissional em Saúde do Adolescente. Para a análise dos dados, foi utilizada a análise de conteúdo de Bardin. A partir da análise das falas dos participantes, foram construídas três categorias analíticas. Os achados do estudo identificaram que os adolescentes que praticavam atividade física antes da pandemia pararam as práticas em algum momento após o início das medidas para contenção da disseminação do vírus. Em relação à saúde mental, foi possível identificar nos relatos os sentimentos de tristeza, medo e insegurança que a pandemia gerou nesses indivíduos. O impacto da pandemia na prática de atividade física e na saúde mental dos adolescentes, segundo a sua perspectiva e os resultados deste estudo, foi negativo.

On March 11, 2020, the World Health Organization recognized that the COVID-19 outbreak had evolved into a pandemic. Isolation measures taken during the pandemic have directly impacted the lives and physical and mental health of both adolescents and the general population. Hence, this study investigates the adolescent perspective regarding physical activity and mental health during the COVID-19 pandemic. A descriptive qualitative study was conducted following a semi-structured interview guide with eleven adolescents aged 11 to 19 years attended by the REMSA team. Data underwent Bardin's content analysis, resulting in three analytical categories. Results showed that adolescents who exercised before the pandemic stopped the practice at some point after the measures to contain the virus spread were implemented. Regarding mental health, the participants mentioned feelings of sadness, fear and insecurity brought by the pandemic. In their perspective, the COVID-19 pandemic negatively impacted physical activity and mental health. These findings impact public health decision-making where strategies to overcome this negative impact on adolescent health must be created for a better quality of life among this population.

El 11 de marzo de 2020, la Organización Mundial de la Salud (OMS) declaró que el brote del covid-19 se ha convertido en una pandemia. Las medidas de aislamiento han tenido un impacto directo en la vida y la salud física y mental de la población en general. El objetivo de este estudio fue conocer la perspectiva del adolescente sobre la práctica de actividad física y salud mental durante la pandemia del covid-19. Se trata de un estudio descriptivo, de enfoque cualitativo, que aplicó una guía semiestructurada a adolescentes de entre 11 y 19 años en seguimiento con el equipo Residencia Multiprofesional en Salud del Adolescente. Para el análisis de datos se utilizó el análisis de contenido de Bardin. A partir del análisis de contenido de los discursos de los participantes, se construyeron tres categorías analíticas. Los hallazgos de este estudio identificaron que los adolescentes que practicaban actividad física antes de la pandemia detuvieron las prácticas en algún momento posterior al inicio de las medidas de contención del virus. En cuanto a la salud mental, los participantes reportaron sentimientos de tristeza, miedo e inseguridad provocados por la pandemia. El impacto de la pandemia del covid-19 en la práctica de actividad física y la salud mental de los adolescentes según su perspectiva y los resultados de este estudio fue negativo.

PROMOTION OF PHYSICAL ACTIVITY AND HEALTHY EATING IN PUBLIC HEALTH: DEVELOPMENT OF VAMOS VERSION 3.0, PRINTED AND ONLINE / ALCANCE Y EFICACIA DEL PROGRAMA "VIDA ACTIVA MEJORANDO LA SALUD" (VAMOS 3.0), IMPLEMENTADO EN ATENCIÓN PRIMARIA DE SALUD EN SANTA CATARINA, BRASIL / ALCANCE E EFICÁCIA DO PROGRAMA "VIDA ATIVA MELHORANDO A SAÚDE" (VAMOS 3.0), IMPLEMENTADO NA ATENÇÃO PRIMÁRIA À SAÚDE EM SANTA CATARINA, BRASIL

Introduction: We developed the intervention Programa Vida Ativa Melhorando a Saúde (VAMOS 3.0). This behavior change program aims to motivate people towards an active and healthy lifestyle. Objective: describe the development process of VAMOS 3.0 in print and online formats. Methods: A methodological study of content analysis, structure, implementation, and evaluation were carried out to develop a new version of VAMOS 3.0. Results: The new version had changes in content (short, direct, and affirmative sentences, images, color palette), structure (increased number of sections, time of application), and implementation (duration, form of participation, monitoring). In addition to the printed format, an online program was created containing the same characteristics to expand the reach. Final considerations: VAMOS 3.0 is suitable for public health in Brazil and has promising strategies for application in basic health units, as well as in other types of institutions such as schools, government offices, gyms, public or private companies.

Introducción: Desarrollamos la intervención Programa Vida Ativa Melhorando a Saúde (VAMOS 3.0). Este programa de cambio de comportamiento tiene como objetivo motivar a las personas hacia un estilo de vida activo y saludable. Objetivo: describir el proceso de desarrollo de VAMOS 3.0 en formato impreso y en línea. Métodos: Se realizó un estudio metodológico de análisis de contenido, estructura, implementación y evaluación para desarrollar una nueva versión de VAMOS 3.0. Resultados: La nueva versión tuvo cambios en contenido (oraciones cortas, directas y afirmativas, imágenes, paleta de colores), estructura (mayor número de secciones, tiempo de aplicación) e implementación (duración, forma de participación, seguimiento). Además del formato impreso, se creó un programa online con las mismas características para ampliar el alcance. Consideraciones finales: VAMOS 3.0 es adecuado para la salud pública en Brasil y tiene estrategias prometedoras para su aplicación en unidades básicas de salud, así como en otro tipo de instituciones como escuelas, oficinas gubernamentales, gimnasios, empresaspúblicas o privadas.

Introdução: Desenvolvemos a intervenção Programa Vida Ativa Melhorando a Saúde (VAMOS 3.0). Este programa de mudança de comportamento visa motivar as pessoas para um estilo de vida ativo e saudável. Objetivo: Descrever o processo de desenvolvimento do VAMOS 3.0 nos formatos impresso e online. Métodos: Foi realizado um estudo metodológico de análise de conteúdo, estrutura, implementação e avaliação para desenvolver uma nova versão do VAMOS 3.0. Resultados: A nova alteração teve no conteúdo (frases curtas, diretas e afirmativas, imagens, paleta de cores), estrutura (aumento do número de versões, tempo de aplicação) e implementação (duração, forma de participação, acompanhamento). Além do formato impresso, foi criado um programa online contendo as mesmas características para ampliar o alcance. Considerações finais: O VAMOS 3.0 é adequado para a saúde pública no Brasil e possui estratégias promissoras para aplicação em unidades básicas de saúde, bem como em outros tipos de instituições como escolas, repartições públicas, academias, empresas públicas ou privadas.

[Determination of the missrreporting of energy intake by Goldberg and Black in the FACSA cohort. Pilot study.] / Determinación de la infradeclaración de la ingesta de energía por el método de Goldberg y Black en la cohorte FACSA. Estudio piloto.

Introduction: Introduction: the Goldberg and Black method estimates dietary underreporting in epidemiological food consumption studies. This method compares the self-reported energy intake of the subjects with the estimate of their total energy expenditure. Objective: to evaluate underreporting and overreporting at individual and group levels in Health Sciences students. Material and methods: the study was cross-sectional and prospective; the participants recorded their food consumption through two dietary records, one on the weekend and the other on the weekdays. They previously answered to sign an informed consent letter, after which the physical activity questionnaire (IPAQ) they were also weighed and measured, and then the basal metabolic rate (BMR) was estimated, It calculated later the declared intake (EI)/BMR ratio, and finally, the cut-off points to determine under-declarers, over declarators and plausible declarators. Results: we found 14.81 % underreporting at the individual level and 44.44 % at the group level. The subjects with a higher BMI and those who performed strenuous physical activity were the ones who underreported the most. The subjects underreported performed moderate and severe physical activity at the group level. Conclusions: it is crucial to carry out this methodology to verify the results of dietary evaluation since underreporting affects the estimation of nutrient intake and can alter the associations between diet and diseases in epidemiological studies.

Introducción: Introducción: el método de Goldberg y Black se utiliza para estimar la infradeclaración dietética en los estudios epidemiológicos de consumo de alimentos. Este método se basa en la comparación de la ingesta de energía autodeclarada por los sujetos con la estimación de su gasto energético total. Objetivo: evaluar la infradeclaración y sobredeclaración a nivel individual y grupal en estudiantes de Ciencias de la salud. Material y métodos: el estudio fue transversal y prospectivo; los participantes registraron el consumo de alimentos por medio de dos registros dietéticos, uno de fin de semana y otro de entre semana. Previamente se les solicitó la firma de una carta de consentimiento informado y después se les aplicó el cuestionario de actividad física (IPAQ). También se les peso y midió, luego se estimó la tasa metabólica basal (BMR), posteriormente se calculó la relación de la ingesta declarada (EI)/BMR y, por último, se eligieron los puntos de corte para determinar quiénes eran infradeclaradores, sobredeclaradores y declaradores plausibles. Resultados: se encontró un 14,81 % de infradeclaración a nivel individual y un 44,44 % a nivel grupal. Los sujetos con mayor IMC y los que realizaban actividad física intensa son los que mayor infradeclaración reportan y, a nivel grupal, los sujetos que realizan actividad física moderada e intensa también fueron infradeclaradores. Conclusiones: es crucial llevar a cabo esta metodología para verificar los resultados de la evaluación dietética ya que la infradeclaración afecta a la estimación de la ingesta de nutrientes y puede alterar las asociaciones entre dieta y enfermedades en los estudios epidemiológicos.

Recomendaciones médicas desde atención primaria sobre ejercicio físico en el posparto / Medical recommendations from primary care on physical exercise in the postpartum

Existe evidencia que demuestra los beneficios de la práctica de actividad física (AF)/ejercicio para la madre después del parto. Sin embargo, este periodo posparto (PP) es, a menudo, una oportunidad perdida en el curso de la vida de las mujeres, para comenzar o reanudar la práctica de ejercicio físico, y obtener los grandes beneficios que esto les puede reportar. El objetivo de este artículo fue analizar los beneficios del ejercicio durante el PP; la prescripción de AF; las recomendaciones sobre el momento de reanudar su práctica; las barreras y facilitadores; el ejercicio físico realizado durante la lactancia materna; así como su papel en las enfermedades y molestias más frecuentes en este periodo, teniendo siempre presente que la labor del médico de atención primaria resulta fundamental para motivar y alentar a las mujeres para que lo practiquen después del parto. (AU)

There is evidence that demonstrates the benefits of practicing physical activity/exercise for the mother after childbirth. However, this postpartum period (PP) is often a missed opportunity in a lifetime for women to start or resume physical exercise and get the great benefits that it can bring them. The objective of this article was to analyze the benefits of physical exercise during PP; the prescription of physical exercise; recommendations on when to resume your practice; barriers and facilitators; physical exercise during breastfeeding; as well as its role in the most frequent illnesses and discomforts in this period, always keeping in mind that the work of the primary care doctor is essential to motivate and encourage women to perform physical exercise in the PP. (AU)

Lifestyles of 2- to 11-year-old children during the CoViD-19 pandemic / Estilos de vida de niños de 2 a 11 años durante la pandemia de COVID-19

Introduction: risk factors associated with obesity such as poor dietary quality, low physical activity (PA), screen time (ST), and poor sleep duration (SD) were affected during confinement resulting from the SARS-CoV-2 pandemic. Objective: the aim of our study was to evaluate the association between PA, ST and SD with the consumption of non-recommended food groups (N-RFG) in children during the COVID-19 pandemic, using data from ENSARS-CoV-2 Girls and Boys. Methods: data were gathered through a self-administered electronic survey carried out in four regions of Mexico during September and October 2020. Dietary patterns were established using k-means cluster analysis. Linear regression models were used to study the effect of food consumption patterns and PA on hours of ST per week. Results: in all, 2,405 children aged 2 to 11 were studied. Three food group consumption patterns were identified. Group 1 or “high consumption of added sugars group” and Group 2 or “high consumption of N-RFG group” children reported more hours of ST than those in Group 3 or “low consumption of N-RFG group” (p < 0.001 and p < 0.001, respectively). Group 2 reported more hours per week of ST but also more days of PA vs Group 3. Conclusion: confronted by the pandemic, it is essential to redouble efforts to reverse the harmful effects of lifestyles during the COVID-19 pandemic to improve the health of Mexican children in the years to come.(AU)

Introducción: los factores de riesgo asociados a la obesidad, como la pobre calidad de la dieta, la baja actividad física (AF), el tiempo frente a pantallas (TP) y la corta duración del sueño (DS), se vieron afectados durante el confinamiento resultado de la pandemia por SARS-CoV-2. Objetivo: el objetivo del estudio fue evaluar la asociación entre AF, TP y DS y el consumo de grupos de alimentos no recomendados (GANR) en niños durante la pandemia por COVID-19, utilizando datos de la ENSARS-CoV-2 Niñas y Niños.Métodos: la información fue recolectada por medio de una encuesta electrónica autoadministrada durante septiembre y octubre de 2020 en las 4 regiones de México. Para establecer patrones de consumo de alimentos se utilizó un análisis de conglomerados por el método de las medias k. Se utilizaron modelos de regresión lineal para estudiar los efectos de los patrones de consumo de alimentos sobre AF y TP. Resultados: la muestra fue de 2,405 niños de 2 a 11 años de edad. Se identifi caron 3 grupos de patrones de consumo de alimentos. El grupo 1 o de “alto consumo de azúcares añadidos” y el grupo 2 o de “alto consumo de GANR” reportaron un mayor número de horas a la semana frente a una pantalla en comparación con el grupo 3 o de “bajo consumo de GANR” (p < 0,001 y p < 0,001, respectivamente). El grupo 2 reportó menos horas a la semana de TP pero también más días de AF con respecto al grupo 3.Conclusión: se ha vuelto esencial duplicar los esfuerzos para revertir los efectos nocivos en los estilos de vida que se establecieron durante la pandemia para mejorar la salud de los niños mexicanos en los años subsecuentes.(AU)

Physical activity as a mediator of the association of body mass index change with anxiety/depression symptoms in Brazilian adults during COVID-19 / La actividad física como mediadora de la asociación de la alteración del índice de masa corporal con síntomas de ansiedad/depresión en adultos brasileños durante la COVID-19

Background: the COVID-19 pandemic has impacted people’s behaviors and mental health around the world. Aim: to verify the mediating role of physical activity (PA) level in the relationship between body mass index (BMI) and anxiety and depression symptoms in adults during the COVID-19 pandemic. Methods: this is a cross-sectional study with Brazilian adults aged ≥ 18 years (N = 2000, 59.6 % women) selected by the nonprobabilistic snowball method through digital means of communication (WhatsApp®, Telegram®, Facebook®, Twitter®, e-mails). Linear regression models were fitted for PA level mediation analyses in the relationship between BMI and anxiety/depression symptoms. Results: significant differences were found between the active/not overweight group and the other three groups (active/overweight, insufficiently active/not overweight and insufficiently active/overweight [p < 0.001]) for anxiety/depression after adjusting for age, sex, chronic diseases, alcohol consumption, and smoking. When testing the mediating role of daily PA in the association between BMI and anxiety/depression symptoms, BMI was negatively associated with daily PA in the first regression equation (p < 0.001); in the second, BMI was positively related to anxiety/depression symptoms (p < 0.001); and in the third, daily PA showed an inverse relationship with anxiety/depression symptoms (p < 0.001), and although BMI remained negatively associated with anxiety/depression symptoms, these associations maintained their statistical significance. Conclusions: the results suggest that the effect of BMI on anxiety and depression was partially mediated by daily PA.(AU)

Introducción: la pandemia de covid-19 ha afectado el comportamiento y la salud mental de las personas en todo el mundo. Objetivo: verificar la mediación del nivel de actividad física (af) en la relación entre el índice de masa corporal (imc) y los síntomas de ansiedad y depresión en adultos durante la pandemia covid-19. Métodos: estudio transversal, con adultos brasileños con edad ≥ 18 años (n = 2.000, 59,6 % mujeres), seleccionados por el método no probabilístico de bola de nieve, a través de medios de comunicación digitales (whatsapp®, telegram®, facebook®, twitter®, correos electrónicos).se ajustaron modelos de regresión lineal para los análisis de la mediación del nivel de actividad física en la relación entre el imc y los síntomas de ansiedad/depresión. Resultados: se encontraron diferencias significativas entre el grupo activo/sin exceso de peso y los otros tres grupos (activo/con exceso de peso, insuficientemente activo/sin exceso de peso e insuficientemente activo/con exceso de peso [p < 0,001]) para ansiedad/depresión después de ajustar por edad, sexo, enfermedades, consumo de alcohol y tabaquismo. al probar el papel mediador de la af diaria en la asociación entre el imc y los síntomas de ansiedad/depresión, en la primera ecuación de regresión, el imc se asoció negativamente con la af diaria (p < 0,001); en la segunda, el imc se relacionó positivamente con los síntomas de ansiedad/depresión (p < 0,001); y en la tercera, la af diaria mostró una relación inversa con los síntomas de ansiedad/depresión (p < 0,001), y aunque el imc mantuvo una asociación negativa con dichos síntomas, estas asociaciones conservaron su significación estadística. Conclusiones: los resultados sugieren que el efecto del imc sobre la ansiedad y la depresión estuvo parcialmente mediado por la actividad física diaria.

Health habits during lockdown for CoViD-19 in Spain and its effect on weight / Hábitos de salud en España durante el confinamiento por COVID-19 y sus efectos sobre el peso

Background and objectives: a deterioration of health habits has been found in various studies caused by stressful situations such as mandatory and maintained confinement over time. This study aims to analyze the health habits of the Spanish adult population during confinement due to the COVID-19 pandemic, and the possible impact on their body weight. Method: two thousand eight hundred and thirty-four volunteer subjects participated in the study (69.3 % women). They completed an on-line questionnaire that evaluated their health habits, as well as various sociodemographic variables. Results: the results show a statistically significant link between the subjects’ body mass index (BMI) and the change in their weight during lockdown (2: 79.303; p: < 0.001). Besides, a statisti-cally significant relationship between the different health habits under analysis was also found, being moderate with respect to the link between eating habits and physical activity (Cramer’s V: .226). A statistically significant relationship was also found between the participants’ weight and the different health habits during lockdown. The effect size of the associations was moderate in relation to the participants’ eating habits (Cramer’s V: .409) and physical activity (Cramer’s V: .292). Conclusions: it is suggested the development of prevention programs for long lockdown periods associated with high levels of stress so as to promote a healthy diet, as well as exercise using new technologies and a proper rest, especially in overweight or obese subjects.(AU)

Antecedentes y objetivos: varios estudios han constatado cómo los hábitos relacionados con la salud pueden verse afectados ante situaciones estresantes, como un confi namiento forzoso y mantenido en el tiempo. El presente estudio tiene como objetivo examinar el impacto que el confinamiento debido a la pandemia por COVID-19 tuvo sobre los hábitos de salud de la población española adulta, así como sobre su peso corporal. Método: en el estudio participaron 2.834 voluntarios (69,3 % mujeres), los cuales cumplimentaron un cuestionario on-line que evaluó sus hábitos de salud, así como diversas variables sociodemográficas. Resultados: los resultados muestran una relación estadísticamente significativa entre el índice de masa corporal (IMC) de los sujetos y el cambio en su peso corporal durante el confinamiento (χ2 : 79,303; p: < 0,001). Una alta proporción de sujetos con sobrepeso (47 %) y obesidad (50,6 %) informaron de un aumento en su peso que podría deberse a un incremento en la ingesta de ali-mentos como resultado de la ansiedad experimentada, cambios en los horarios de las comidas, una disminución del tiempo dedicado al ejercicio físico y un empeoramiento de la cantidad y la calidad del sueño. Asimismo, se encontró una relación estadísticamente significativa entre los diferentes hábitos de salud objeto de estudio, siendo esta moderada entre los hábitos alimentarios y la actividad física (V de Cramer: 0,226). También se encontró una relación estadísticamente significativa entre el peso de los participantes y sus diferentes hábitos de salud durante el confinamiento, siendo esta moderada en relación con los hábitos de alimentación de los participantes (V de Cramer: 0,409) y su actividad física (V de Cramer: 0,292). Conclusiones: se sugiere elaborar planes de prevención para confinamientos prolongados asociados a altos niveles de estrés, dirigidos especialmente a personas con sobrepeso y obesidad, los cuales promuevan una alimentación saludable junto...(AU)

Composición corporal, hábitos alimentarios y actividad físicaen estudiantes universitarios. Lima-Perú / Body composition, eating habits and physical activity in university students. Lima-Perú

Introducción: En el contexto actual epidemiológico y nutricional urge el conocimiento acerca de los hábitos alimentarios, estilos de vida y condición nutricional de jóvenes universitarios.Objetivo: Identificar composición corporal, hábitos alimentarios y actividad física en universitarios.Materiales y Métodos: Estudio observacional - transversal (n=118). Las variables fueron: Edad, Sexo, Peso, Talla, IMC, Masa grasa corporal, Masa muscular esquelética, Grasa visceral, Circunferencia de cintura, hábitos alimentarios y de actividad física. Se usó balanza digital OMRON de impedancia bioeléctrica. El consumo de alimentos fuente de grasa, fruta, vegetales y fibra se obtuvo con el Cuestionario de tamizaje de Block. Se usó el International Physical Activity Questionnaire IPAQ corta, que evalúa la actividad física.Resultados: La masa muscular esquelética es mayor en varones (38%) que en mujeres (25%). Caso contrario se observó en el contenido de grasa corporal, en mujeres 37% y 24% en varones. Se encontró diferencia en el porcentaje de grasa corporal, mujeres (37%) y varones (24%). Todas estas diferencias son estadísticamente significativas (p-valor < 0.05). En hábitos alimentarios se evidenció que el 19% presentó dieta alta y muy alta en grasa y en cuanto al consumo de frutas, vegetales y fibra, se evidenció que menos del 1% presentó consumo normal. Respecto a actividad física, el 46% indicó realizar actividad física alta, 52% moderada y el 2.5% actividad baja. No se encontró diferencias estadísticamente significativas en cuanto a las variables de estudio según rangos de edad (< 19 años vs >=19 años).Conclusiones: La composición corporal permitió cuantificar las reservas corporales del organismo de los estudiantes, el porcentaje de estos componentes corporales fue variable y depende del sexo. Un bajo porcentaje de estudiantes presentaron adecuados consumos de frutas, vegetales y fibra, los hombres tienen un mayor nivel de actividad física.(AU)

Introduction: In the current epidemiological and nutri-tional context, knowledge about the eating habits, lifestyles,and nutritional conditions of young university students is ur-gently needed.Objective: To identify body composition, eating habits,and physical activity in university students. Materials and Methods: Observational-cross-sectionalstudy. The population consisted of university students between16 and 25 years of age (n = 118). The variables studied were:age, sex, weight, height, BMI, body fat mass, skeletal musclemass, visceral fat, waist circumference, dietary habits, andphysical activity. Body composition was measured by anthro-pometry and bioelectrical impedance. Food consumption wasobtained with the Block Screening Questionnaire. The shortInternational Physical Activity Questionnaire (IPAQ) was usedto assess physical activity. Chi-Square and T-Student tests wereused as hypothesis contrasts. To determine associations be-tween variables, a p-value <0.05 was considered statisticallysignificant.Results: Skeletal muscle mass was higher in males (38%)than in females (25%), while body fat was higher in females(37%) than in males (24%). These differences were statisti-cally significant. Regarding dietary habits, 19% had a diet highand very high in fat, and less than 1% had normal consump-tion of fruits, vegetables, and fiber. Regarding physical activity,46% indicated high physical activity, 52% moderate, and2.5% low activity. It was observed that men had more highphysical activity than women; however, women had moremoderate and low physical activity than men (p = 0.0299). Nostatistically significant differences were found for the studyvariables according to age ranges.Conclusions: Body composition was variable and sex-de-pendent. A minimum percentage of university students hadadequate intakes of fruits, vegetables, and fiber. Men had ahigher level of physical activity than women.(AU)

Time dedicated to physical activity among medical residents: are there differences based on gender or specialty type?

INTRODUCTION: Physical activity (PA) is associated with positive health outcomes such as prevention of chronic diseases, psychological well-being and improved work performance. Medical residents are subjected to sleep deprivation, extended work schedule and high burnout prevalence. These conditions may lead to the neglect of personal health and the restriction of time dedicated to PA. The objective of the present study was to analyze the time dedicated to PA of medical residents, comparing women vs men residents and surgical vs clinical residents. METHODS: It is a cross-sectional study performed in a Spanish third-level university hospital. All medical residents from our institution were invited to voluntarily participate in the study answering a web-based questionnaire on June 2022. Data regarding demographics, residency and PA practice was recorded. RESULTS: The response rate was 20.73% (114/550). The 32.5% of the residents considered themselves to be physically inactive and mean time dedicated to PA in a regular week was 3.62 ±â€¯2.22 h. Men residents dedicated more time to PA than women residents (4.23 ±â€¯2.42 h vs 3.14 ±â€¯1.95 h, p = 0.012) and surgical residents dedicated more time than clinical residents (4.33 ±â€¯2.36 h vs 3.23 ±â€¯2.05 h, p = 0.01). CONCLUSIONS: One third of the medical residents consider themself physically inactive. Women and clinical residents practice PA less time than men and surgical residents. Efforts should be made to encourage PA among residents, especially in women and non-surgeons.