Changes of AC activity and content of cAMP in hypothalamus of rats with fever and hypothermia / 中国病理生理杂志

AIM: To observe the changes of AC activity and content of cAMP at different time point in hypothalamus of rats with fever and hypothermia. METHODS: Radioisotope method was used to measure the enzymatic activity of AC and the content of cAMP. RESULTS:(1)The fresh yeast caused fever after making model 4 h( P

THE CHANGES OF CYCLIC NUCLEOTIDES IN PLASMA, PANCREAS AND LUNGS DURING EARLY PHASE OF ACUTE HEMORRHAGIC PANCREATITIS IN DOGS / 第二军医大学学报

Cyclic nucleotides in plasma, lung and pancreas were determined by radio-competitive protein binding assay before and after acute experimental pancreatitis in dogs. Plasma cAMP was increased three-fold 30 minutes after pancreatitis and remained at high level for 5 hours. cAMP was increased in the lungs and decreased in the pancreas,as compared with the controls.There were no significant changes for cGMP. The mechanisms of the above changes were discussed.