Subject(s)
Humans , Male , Female , Adrenal Cortex Hormones , Drug Hypersensitivity , Pharmaceutical Preparations , Polyethylene Glycols , Gelatin , PolysorbatesABSTRACT
Se exponen datos relacionados con la histología, fisiología y patología de los mastocitos, tanto normales como patológicos, y el papel de la alergia medicamentosa en la mastocitosis, así como las repercusiones psicopatológicas de la enfermedad y las bases neuroquímicas de dichos trastornos.
Data concerning the biological aspects of mastocytes, its pathology and the importance of childhood and adult mastocytosis are described. The role of drug allergy in mastocytosis is discussed. The psychopathological and neurochemical aspects of these conditions are exposed.
Subject(s)
Humans , Drug Hypersensitivity , Mastocytosis, Systemic/diagnosis , Mastocytosis, Systemic/psychology , Mastocytosis, Systemic/therapy , Desensitization, Immunologic , Mastocytosis, Systemic/physiopathology , Mutation/genetics , PsychotherapyABSTRACT
Se hace una breve descripción sobre la epidemiología y la clasificación de las reacciones adversas a medicamentos. Se conceptualiza la reacción por idiosincrasia y se expresan los criterios comunes entre la idiosincrasia y la reacción por hipersensibilidad. Se explica brevemente cómo un medicamento se convierte en alergeno y se enumeran los factores que influyen en el potencial alérgico de un medicamento. Se describen las manifestaciones alérgicas que corresponden a las reacciones inmunológicas de Gell y Coombs. Se exponen los pasos a seguir ante una probable alergia medicamentosa y se relatan algunos aspectos primordiales de la alergia a algunos medicamentos en particular(AU)
A brief description is made about the epidemiology and classification of adverse reactions to medications. The reaction is conceptualized by idiosyncrasy and common approaches are expressed between idiosyncrasy and a reaction by hypersensitivity. A brief explanation is given of how a medication becomes allergenic, and the factors that influence in the allergic potential of a medication are enumerated. The allergic manifestations that correspond to immunologic reactions of Gell and Coombs are described. The steps to follow before a probable drug-induced allergy are exposed, and some essential aspects of allergy to some medications in particular are related(AU)
