ABSTRACT
Objective: To study the curative effect of ofloxacin ear drops combined with Bairui Granules on acute suppurative otitis media in children. Methods: A total of 186 pediatric patients with acute suppurative otitis media treated in Qinhuangdao City Chinese Medicine Hospital were divided into the treatment group and control group according to the random number table method. In the treatment group, 94 patient were treated with 0.3% ofloxacin ear drops combined with Bairui Granules. In the control group, children in the 92 cases only received ofloxacin ear drops (2-3 times a day, 6-10 drops each time; After ear dropping, taking 10 min ear bath). Each group was treated 7-10 d. The curative effect and adverse reactions were observed. Results: The total effective rate of the treatment group was 94.68% and the control group was 82.61%, there was a significant difference between the two groups. (P < 0.05). The improvement in symptom and physical scores of the treatment group was significantly better than that of the control group (P < 0.05). There was no significant difference in the incidence of adverse reactions between two groups. Conclusion: The ofloxacin ear drops can efficiently improve clinical symptoms of the patients with acute suppurative otitis media, and Bairui Granules have antipyretic and antiphlogistic effect. The combination of the two drugs had significant curative effect on acute suppurative otitis media in children with low adverse reactions incidence, so we conclude that it is worthy to be promoted.
ABSTRACT
Objective To observe the curative effect of tonsil-pecking method combined with Bairui Granules for the treatment of chronic tonsillitis. Methods A total of 116 patients with chronic tonsillitis treated in Qinhuangdao City Chinese Medicine Hospital from January 2017 to June 2018 were randomly divided into the treatment group and the control group according to the random number table method. Sixty-six cases in the treatment group were treated with tonsil-pecking method combined with Bairui Granules, tonsil-pecking method once 3 d, Bairui Granules one bag (5 g) three times daily. Fifty cases in the control group were only received tonsil-pecking method. One course was 7 d, both groups were treated for two courses. Result The total effective rate of the treatment group was 93.9%, which of the control group was 92.0%, there was no significant difference in the efficacy between the two groups (P > 0.05). But the significant effective rates of the treatment group was 80.3%, which of the control group was 68.0%, there was a significant difference between the two groups (P < 0.05). And the improvement in symptom and physical signs of the treatment group was significantly better than the cntrol group (P < 0.05). Conclusion Tonsil-pecking method can disperse swelling and stasis. Bairui Granules have antipyretic and antiphlogistic effect, combination administration had higher cure rate in the treatment of chronic tonsillitis, symptoms and signs were improved significantly.
ABSTRACT
Objective To observe the curative effect of Bairui Granules combined with amoxicillin and clavulanate potassium tablets in treating acute tonsillitis. Methods A total of 200 patients with acute tonsillitis treated in Dongfang Hospital from February to November in 2017 were randomly divided into the treatment group and the control group according to the random number table method. A total of 100 cases in the control group was treated with amoxicillin and clavulanate potassium tablets, 100 cases in the treatment group received Bairui Granules combined with amoxicillin and clavulanate potassium tablets, each group was treated for 5 d as one course. The clinical symptoms and signs improving time of two groups were observed and the therapeutic effects of the two groups were compared and analyzed. Result In the treatment group, the time of heat withdrawal and sore throat disappeared was significantly less than that of the control group (P < 0.01); After one course of treatment, the total effective rate of the treatment group was significantly higher than that of the control group (P < 0.05). In the two groups, there was no adverse reaction during the treatment. Conclusion Bairui Granules combined with amoxicillin and clavulanate potassium tablets had the advantages of short course and higher effect in the treatment of acute tonsillitis.
ABSTRACT
To observe the efficacy of Bairui granules combined with ribavirin aerosol in the treatment of children with seasonal influenza. Methods:Totally 60 cases of children with seasonal influenza were randomly divided into the observation group and the control group with 30 ones in each. The children in the control group were given ribavirin aerosol, and the children in the observa-tion group were given ribavirin aerosol combined with Bairui granules. The disappearance time of symptoms and curative effect of the two groups were observed after the treatment. Results:The total effective rate of the observation group was 96. 67%,that of the control group was 86. 67%,and the difference was not statistically significant (P>0. 05). The time of fever relieving, the disappearance time of headache, whole body pain and red and swollen thoroat and cough in the observation group were all significantly shorter than those in the control group (P<0. 05 or P<0. 01). Conclusion: Bairui granules combined with ribavirin aerosol is an effective method in the treatment of children with seasonal influenza.
