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1.
Rev Esp Anestesiol Reanim (Engl Ed) ; 71(3): 141-150, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38452925

ABSTRACT

BACKGROUND AND OBJECTIVES: The harmful effects of excess fluids frequently manifest in the lungs. Thoracic fluid content (TFC) is a variable provided by the STARLINGTM bioreactance monitor, which represents the total volume of fluid in the chest. The objective is to analyse the association between the variation in TFC values (TFCd0%) at 24 h postoperatively, postoperative fluid balance, and postoperative pulmonary complications. MATERIAL AND METHODS: Prospective and analytical observational study. Patients scheduled for major abdominal surgery at a tertiary teaching hospital were included. They were monitored during the intervention and the first 24 postoperative hours with the monitor. STARLINGTM, measuring TFC and its variation in different stages of the perioperative period. Serial lung ultrasounds were performed and postoperative pulmonary complications were recorded. Logistic regression was performed to predict the occurrence of atelectasis and pulmonary congestion. The Pearson correlation coefficient was calculated to verify the association between TFC and fluid balance. RESULTS: 50 patients were analyzed. TFCd0% measured on the morning of the first postoperative day increased by a median of 27.1% [IQR: 20.3-37.5] and was correlated at r = 0.44 with the postoperative balance of 677 ml [IQR: 125.5-1,412]. Increased TFC was related to a higher risk of atelectasis (OR = 1.24) and pulmonary congestion (OR = 1.3). CONCLUSIONS: TFCd0% measured 24 h after surgery presents a moderate correlation with postoperative fluid balance. Its increase is a risk factor for the appearance of postoperative pulmonary complications.


Subject(s)
Abdomen , Postoperative Complications , Water-Electrolyte Balance , Humans , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Male , Prospective Studies , Female , Middle Aged , Aged , Abdomen/surgery , Lung Diseases/etiology , Body Fluids
2.
Rev. esp. anestesiol. reanim ; 71(3): 141-150, Mar. 2024. ilus, tab, graf
Article in Spanish | IBECS | ID: ibc-230927

ABSTRACT

Antecedentes y objetivos: Los efectos nocivos del exceso de líquidos se manifiestan frecuentemente en los pulmones. El contenido de fluido torácico (thoracic fluid content [TFC]) es una variable que proporciona el monitor por biorreactancia STARLING™, que representa el volumen total de líquido en el tórax. El objetivo es analizar la asociación entre la variación de los valores del TFC (TFCd0%) a las 24horas postoperatorias, el balance hídrico postoperatorio y las complicaciones pulmonares postoperatorias. Material y métodos: Estudio observacional prospectivo y analítico. Se incluyeron pacientes programados para cirugía abdominal mayor en un hospital universitario de tercer nivel. Fueron monitorizados durante la intervención y las 24 primeras horas postoperatorias con el monitor STARLING™, midiendo el TFC y su variación en distintas etapas del perioperatorio. Se realizaron ecografías pulmonares seriadas y se recogieron las complicaciones pulmonares postoperatorias. Se realizó una regresión logística para predecir la aparición de atelectasias y congestión pulmonar. Se calculó el coeficiente de correlación de Pearson para comprobar la asociación entre TFC y balance hídrico. Resultados: Se analizaron 50 pacientes. El TFCd0% medido en la mañana del primer día postoperatorio aumentó una mediana del 27,1% [IQR: 20,3-37,5] y se correlacionó con una r=0,44 con el balance postoperatorio de 677ml [IQR: 125,5-1.412]. El aumento del TFC se relacionó con un mayor riesgo de sufrir atelectasias (OR=1,24) y congestión pulmonar (OR=1,3). Conclusiones: El TFCd0% medido a las 24horas de la cirugía presenta una correlación moderada con el balance hídrico postoperatorio. Su incremento es un factor de riesgo para la aparición de complicaciones pulmonares postoperatorias.(AU)


Background and objectives: The harmful effects of excess fluids frequently manifest in the lungs. Thoracic fluid content (TFC) is a variable provided by the STARLINGTM bioreactance monitor, which represents the total volume of fluid in the chest. The objective is to analyze the association between the variation in TFC values (TFCd0%) at 24 hours postoperatively, postoperative fluid balance, and postoperative pulmonary complications. Material and methods: Prospective and analytical observational study. Patients scheduled for major abdominal surgery at a tertiary teaching hospital were included. They were monitored during the intervention and the first 24 postoperative hours with the monitor. STARLINGTM, measuring TFC and its variation in different stages of the perioperative period. Serial lung ultrasounds were performed and postoperative pulmonary complications were recorded. Logistic regression was performed to predict the occurrence of atelectasis and pulmonary congestion. The Pearson correlation coefficient was calculated to verify the association between TFC and water balance. Results: 50 patients were analyzed. TFCd0% measured on the morning of the first postoperative day increased by a median of 27.1% [IQR: 20.3-37.5] and was correlated at r=0.44 with the postoperative balance of 677 ml [IQR: 125.5-1,412]. Increased TFC was related to a higher risk of atelectasis (OR=1.24) and pulmonary congestion (OR=1.3). Conclusions: TFCd0% measured 24 hours after surgery presents a moderate correlation with postoperative fluid balance. Its increase is a risk factor for the appearance of postoperative pulmonary complications.(AU)


Subject(s)
Humans , Male , Female , Postoperative Complications , Abdomen/surgery , Pulmonary Edema , Pulmonary Atelectasis , Prospective Studies , Anesthesiology
3.
Med. crít. (Col. Mex. Med. Crít.) ; 30(5): 290-300, nov.-dic. 2016. tab
Article in Spanish | LILACS | ID: biblio-1040398

ABSTRACT

Resumen: El periodo de reanimación después del trasplante hepático ortotópico (THO) es un desafío debido a las alteraciones fisiológicas relacionadas con la enfermedad hepática terminal (EHT). Material y métodos: Este es un estudio retrospectivo que evalúa las primeras 48 horas de manejo en la unidad de cuidados intensivos (UCI) de un hospital de la Ciudad de México. Los pacientes se clasificaron en 4 grupos según la dosis de norepinefrina (NADR) utilizada y el balance neto de líquidos (BalT): Grupo 1 norepinefrina menos de 0.1 μg/1 kg/min/BalT 3,805 ml, grupo 2 norepinefrina mayor de 0.1 μg/kg/min/BalT menos de 3,805 ml, grupo 3 norepinefrina menos de 0.1 μg/kg/min/BalT mayor de 3,805 ml, grupo 4 norepinefrina mayor de 0.1 μg/kg/min/BalT mayor de 3,805 ml. Se evaluó el desarrollo de complicaciones Post-THO. Las variables principales de valoración fueron; complicaciones médicas generales, reoperación quirúrgica y duración de estancia en el hospital (DEH), duración de la ventilación mecánica, lesión renal aguda, función anormal del injerto y cultivos positivos. Resultados: 36.6% de los pacientes pertenecían al grupo 1, 18.8% al grupo 2, 17.8% al grupo 3 y 26.7% al grupo 4. La duración de la estancia fue de 3.39 días, tiempo medio de ventilación mecánica de 16.5 horas. El 67% desarrolló complicaciones médicas, el 15.8% de reoperación quirúrgica, el 62% de lesión renal aguda, el 50.5% de función anormal del injerto y el 45.5% de cultivos perioperatorios positivos. La duración de la estancia fue de 3.39 días, tiempo medio de ventilación mecánica de 16.5 horas. De estos criterios de valoración primarios, sólo la duración de la estancia y la duración de la ventilación mecánica fueron diferentes entre los grupos. Conclusiones: La duración de la estancia y la necesidad de ventilación mecánica, fueron diferentes entre los grupos. El desarrollo de otros criterios de valoración primarios fue independiente del modelo de resucitación.


Abstract: The resuscitation period after orthotopic liver transplantation (OLT) is challenging due to the physiological alterations related to end stage liver disease (ESLD). Material and methods: This is a retrospective study assessing the first 48 hours management at the intensive care unit (ICU) of at hospital in México City. Patients were categorized into 4 groups according to norepinephrine (NADR) dose used and net fluid balance (BalT): group 1 norepinephrine < 0.1 μg/1 kg/min/BalT 3,805 mL, group 2 norepinephrine > 0.1 μg/kg/min/BalT < 3,805 mL, group 3 norepinephrine < 0.1 μg/kg/min/BalT > 3,805 mL, group 4 norepinephrine > 0.1 μg/kg/min/BalT > 3,805 mL. The relationship with the development of Po-OLT complications was assessed. Primary endpoints were general medical complications, surgical reoperation, and length of stay (LOS), length of mechanical ventilation, acute kidney injury, abnormal graft function and positive cultures. Results: 36.6% of the patients belonged to group 1, 18.8% to group 2, 17.8% to group 3, and 26.7% to group 4. The length of stay was 3.39 days, mean time of mechanical ventilation of 16.5 hours. 67% developed medical complications, 15.8% surgical reoperation, 62% acute kidney injury, 50.5% abnormal graft function and 45.5% positive perioperative cultures. Of these primary endpoints, only length of stay and length of mechanical ventilation were different among groups. Conclusions: Length of stay and mechanical ventilation need was different among groups. Development of other primary endpoints was independent of the resuscitation model.


Resumo: O período de reanimação no pós-operatório de transplante hepático ortotópico (THO) é um desafio devido a alterações fisiológicas relacionados com a doença hepática terminal (DHT). Material e métodos: Realizou-se um estudo retrospectivo que avaliou as primeiras 48 horas do THO na unidade de terapia intensiva (UTI) de um hospital na Cidade do México. Os pacientes foram classificados em 4 grupos de acordo com a dose de norepinefrina (NADR) utilizada e o balaço hidrico (BalT): grupo 1 norepinefrina menor de 0.1 μg/1 kg/min/BalT menor de 3.805 ml, grupo 2 norepinefrina maior de 0.1 μg/kg/min/BalT menor de 3.805 ml, grupo 3 norepinefrina menor de 0.1 μg/kg/min/BalT maior de 3.805 ml, grupo 4 norepinefrina maior de 0.1 μg/kg /min/BalT maior de 3.805 ml. Analizou-se a relação que existe com o desenvolvimento de complicações Post-THO. As principais variáveis da avaliação foram: complicações médicas, reintervenção cirúrgica e tempo de permanência hospitalária, duração da ventilação mecânica, lesão renal aguda, função anormal do enxerto e cultivos positivos. Resultados: 36.6% dos pacientes pertenciam ao grupo 1, 18.8% ao grupo 2, 17.8% para o grupo 3 e 26.7% ao grupo 4. O tempo de permanência hospitalar foi 3.39 dias, ventilação mecânica de 16.5 horas tempo médio. 67% desenvolveram complicações médicas, 15.8% reintervenção cirúrgica, 62% de lesão renal aguda, 50.5% função anormal do enxerto e 45.5% de cultivos pré-operatórios positivos. Destes parâmetros, o TEUTI e TVM apresentaram diferenças entre os modelos de reanimação. Conclusão: O TEUTI e TVM variaram de acordo ao modelo de reanimação. Os outros resultados primários foram independentes ao modelo de reanimação.

4.
Arch. argent. pediatr ; 114(4): 313-318, ago. 2016. ilus, tab
Article in English, Spanish | LILACS, BINACIS | ID: biblio-838239

ABSTRACT

Introducción. Se han descrito asociaciones entre balance de fluido acumulado y mayor estadía en asistencia respiratoria mecánica en adultos. El objetivo fue evaluar si el balance de las primeras 48 horas de iniciada la asistencia respiratoria mecánica se asociaba a su prolongación en niños internados en Terapia Intensiva Pediátrica (UCIP). Métodos. Cohorte retrospectiva de pacientes de la UCIP del Hospital Italiano de Buenos Aires, entre el 1/1/2010 y el 30/6/2012. El balance se calculó en porcentaje del peso corporal; ventilación mecánica prolongada se definió como > 7 días y se registraron confundidores. Se realizó un análisis univariado y multivariado. Resultados. 249 pacientes permanecieron ventilados más de 48 horas; se incluyeron 163. El balance de las primeras 48 horas en ventilación mecánica fue 5,7%±5,86; 82 pacientes (50,3%) permanecieron más de 7 días con respirador. La edad < 4 años (OR 3,21; IC 95% 1,38-7,48; p 0,007), enfermedad respiratoria (OR 4,94; IC 95% 1,51-16,10; p 0,008), shock séptico (OR 4,66; IC 95% 1,10-19,65; p 0,036), puntaje de disfunción orgánica (PELOD) > 10 (OR 2,44; IC 95% 1,23-4,85; p 0,011) y balance positivo > 13% (OR 4,02; IC 95% 1,08-15,02; p 0,038) se asociaron a ventilación mecánica prolongada. El modelo multivariado mostró para PELOD > 10 un OR 2,58; IC 95%: 1,17-5,58; p 0,018, y para balance positivo > 13% un OR 3,7; IC 95%: 0,91-14,94; p 0,066. Conclusiones. En relación a ventilación mecánica prolongada, el modelo multivariado mostró una asociación independiente con disfunción de órganos (PELOD > 10) y una tendencia hacia la asociación con balance positivo > 13%.


Introduction. Associations between cumulative fluid balance and a prolonged duration of assisted mechanical ventilation have been described in adults. The aim of this study was to evaluate whether fluid balance in the first 48 hours of assisted mechanical ventilation initiation was associated with a prolonged duration of this process among children in the Pediatric Intensive Care Unit (PICU). Methods. Retrospective cohort of patients in the PICU of Hospital Italiano de Buenos Aires, between 1/1/2010 and 6/30/2012. Balance was calculated in percentage of body weight; prolonged mechanical ventilation was defined as >7 days, and confounders were registered. Univariate and multivariate analyses were performed. Results. Two hundred and forty-nine patients were mechanically ventilated for over 48 hours; 163 were included in the study. Balance during the first 48 hours of mechanical ventilation was 5.7% ± 5.86; 82 patients (50.3%) were on mechanical ventilation for more than 7 days. Age < 4 years old (OR 3.21, 95% CI 1.38-7.48, p 0.007), respiratory disease (OR 4.94, 95% CI 1.51-16.10, p 0.008), septic shock (OR 4.66, 95% CI 1.10-19.65, p 0.036), Pediatric Logistic Organ Dysfunction (PELOD) > 10 (OR 2.44, 95% CI 1.234.85, p 0.011), and positive balance > 13% (OR 4.02, 95% CI 1.08-15.02, p 0.038) were associated with prolonged mechanical ventilation. The multivariate model resulted in an OR 2.58, 95% CI: 1.17-5.58, p= 0.018 for PELOD > 10, and an OR 3.7, 95% CI: 0.91-14.94, p= 0.066 for positive balance > 13%. Conclusions. Regarding prolonged mechanical ventilation, the multivariate model showed an independent association with organ dysfunction (PELOD > 10) and a trend towards an association with positive balance > 13%.


Subject(s)
Humans , Child, Preschool , Child , Respiration, Artificial , Water-Electrolyte Balance , Intensive Care Units, Pediatric , Patient Admission , Time Factors , Retrospective Studies
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