Impulsivity Traits in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Background: In Parkinson's disease (PD), impulsivity as a personality trait may be linked to the risk of developing impulse control disorders (ICDs) during dopaminergic therapy. However, studies evaluating differences in trait impulsivity between patients with PD and healthy controls or between patients with PD with and without ICDs reported partly inconsistent findings. Objectives: We conducted a systematic review and meta-analysis (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) of studies comparing Barratt Impulsiveness Scale (BIS-11) scores between patients with PD and healthy controls and between patients with PD with and without ICDs. Methods: Eligible studies were identified through a systematic search in 3 databases. Mean differences with 95% confidence intervals (CIs) for BIS-11 total and subscale scores were separately calculated for studies comparing patients with PD and healthy controls and patients with PD with and without ICDs. Meta-regressions were performed to explore sources of heterogeneity (percentage of men, age, disease duration, and levodopa equivalent daily dose). Results: A total of 40 studies were included in the quantitative analyses. BIS-11 total scores were significantly higher in patients with PD compared with healthy controls (mean difference 2.43; 95% CI, 1.03, 3.83), and in patients with PD with active ICDs compared with patients without ICDs (6.62; 95% CI, 5.01, 8.23). No significant moderators emerged by meta-regression analyses. Conclusions: The present meta-analysis supports that impulsivity, as a personality trait, may characterize patients with PD, even in the absence of ICDs. Moreover, these data corroborate findings of clinical studies reporting higher levels of trait impulsivity in PD patients with ICDs compared with patients without ICDs.

Swimming Activity Alleviates the Symptoms of Attention: Deficit Hyperactivity Disorder (ADHD) a Case Report.

Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder characterized by inattention, hyperactivity, and impulsivity. Sport and physical activity have been shown to play a major role in the development of cognition, memory, selective attention, and motor reaction time, especially among adolescents with ADHD. In this context, the objective of this study was to investigate the effects of a swimming exercise program on the symptoms of ADHD in an adult with a diagnosis since childhood. The training intervention was performed for eight weeks, and the results demonstrated that the swimming-learning program significantly alleviated the symptoms of inattention and hyperactivity, as measured by the psychometric indices used in the study. Further studies are needed to establish and understand the association between physical activities and improved mental performance in adults with ADHD.

Psychometric properties of the Arabic version of Barratt Impulsiveness Scale 11: The development of short form.

Impulsivity is an important mental health-related variable that has been associated with various human behaviors. The Barratt Impulsiveness Scale is the most frequently used measure to examine impulsivity. However, its psychometric and factor structure was not examined in Arabic speaking population. The goal of the current study was to examine the psychometric properties and factor structure of the Barratt Impulsiveness Scale in Arabic speaking population. The current study used a cross-sectional design. Two independent samples were recruited: college students (N = 250) and persons with heart failure (N = 165). Exploratory factor analysis, then a series of confirmatory factor analyses were used to assess one- and three-factor models of the Barratt Impulsiveness Scale (30 items; i.e., BIS-11) and Barratt Impulsiveness Scale (15 items; i.e., BIS-15). Because our analysis did not support the factor structure of the previous versions of the Barratt Impulsiveness Scale, we used confirmatory factor analysis to evaluate the model structure of the single-factor measure. To assess the measurement invariance, the newly developed measure was examined across different genders and populations. Due to poor psychometrics of BIS-11 and BIS-15, a short form (BIS-SF) was developed; and validity, reliability, and measurement invariance were supported. The current analysis showed that BIS-11 and BIS-15 have poor psychometrics. Thus, there was a need to improve the measure by reducing the number of items and re-evaluating the psychometrics of the new measure. The BIS-SF is a reliable, valid tool to assess impulsivity in our samples. Other studies need to support the current study findings in populations with other chronic illnesses.

Impulsivity and Attention in Obsessive Compulsive and Tic Disorders: Mismatch in Self-Report and Behavioural Data.

Impulsivity is a multidimensional, cross-diagnostic behavioural construct that has been described in various psychiatric disorders including obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). Different interpretations of results in the past have raised the question of heightened impulsivity as an explanatory model for self-described impulsive behaviour, especially in OCD. Our study included 16 patients with OCD, 14 patients with TS, and 28 healthy control subjects (HC). Self-assessed impulsivity was examined by the Barratt Impulsiveness Scale-11 (BIS-11), and the behavioural test used was the immediate and delayed memory task (IMT/DMT). Significantly heightened self-assessed impulsivity of the patient collective compared to HC could be observed in in only one dimension: lack of attention (χ2 (2) = 24.910, p < 0.001). Post-hoc tests were performed using Bonferroni adjusted alpha levels of 0.0167 per test (0.05/3) and revealed significantly higher scores in patients with OCD (M = 19.57, SD = 2.82), z = 4.292, p < 0.001 as with TS (M = 19.38, SD = 3.62), z = 3.832, p < 0.001 compared to HC (M = 13.78, SD = 3.18). In patients with OCD, correlations between the dimension of obsessive thoughts with a lack of attention in the form of first-order factor cognitive instability could be shown (n = 14, p = 0.024, rs = 0.599) while in patients with TS, tic symptomatology correlated significantly with second-order factor attentional impulsivity (n = 12, p = 0.027, rs = 0.635). In behavioural testing, no significant group differences could be observed either in impulsive behaviour (IMT: χ2 (2) = 4.709, p = 0.824; DMT: χ2 (2) = 0.126, p = 0.939) or in sustained attention (IMT: χ2 (2) = 0.388, p = 0.095; DMT: χ2 (2) = 0.663, p = 0.718). Heightened impulsivity as an explanatory model for the observed lack of attention, especially in patients with OCD, should be questioned and interpretation biases considered in the future. The necessity of a multidimensional approach to the research of impulsivity is underscored by our results.

Impulsividad en el trastorno por déficit de atención e hiperactividad en niños después de una intervención de 8 semanas con dieta mediterránea y/o ácidos grasos omega-3: ensayo clínico aleatorizado / Impulsiveness in children with attention-deficit/hyperactivity disorder after an 8-week intervention with the Mediterranean diet and/or omega-3 fatty acids: A randomised clinical trial

Introducción: La Escala de Impulsividad de Barratt (BIS) es un instrumento de autoinforme diseñado para evaluar la construcción de personalidad y comportamiento de la impulsividad. La impulsividad se ha asociado con varios trastornos psiquiátricos, como el trastorno por déficit de atención e hiperactividad (TDAH). Este estudio evalúa el progreso de la conducta de impulsividad en niños con TDAH después de una intervención dietética de 8 semanas con dieta mediterránea y/o suplemento de ácidos grasos omega-3, mediante el uso de la BIS-11 adaptada para niños (BIS-11c). Métodos: Este estudio transversal incluyó a 60 niños españoles con TDAH de la provincia de Madrid, España. Los participantes se dividieron en 4 grupos, un grupo de control (G1) y 3 grupos de intervención (dieta mediterránea [G2], suplemento de omega-3 [G3] y dieta mediterránea + suplemento de omega-3 [G4]). Se diseñó una dieta mediterránea personalizada para los grupos 2 y 4. Se administró BIS-11c para determinar los niveles de impulsividad y se usó el KIDMED para evaluar la adherencia a la dieta mediterránea. Resultados: El grupo suplemento mostró una caída bastante significativa (p = 0,049) en la puntuación total de Barratt después del seguimiento. La puntuación cognitiva total disminuyó ligeramente en los grupos de dieta y suplemento. Solo el grupo control tuvo una disminución notable con respecto a la puntuación total de la impulsividad motora. Las puntuaciones totales de «falta de planificación» fueron menores en todos los grupos tras la intervención. Las asociaciones entre las puntuaciones iniciales y finales del BIS-11c y los tratamientos presentaron una correlación positiva (r > 0,9). [...](AU)

Introduction: The Barratt Impulsiveness Scale (BIS) is a self-administered instrument designed to assess the personality/behavioural construct of impulsiveness. Impulsiveness has been associated with several psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). This study assesses the progression of impulsive behaviour in children with ADHD after an 8-week dietary intervention with the Mediterranean diet and/or omega-3 fatty acid supplementation, by using a version of the 11-item BIS adapted for children (BIS-11c). Methods: This cross-sectional study includes 60 children with ADHD from the region of Madrid, Spain. Participants were divided into 4 groups, with one control group (G1) and 3 intervention groups (Mediterranean diet [G2]; omega-3 supplementation [G3]; and Mediterranean diet plus omega-3 supplementation [G4]). A personalised Mediterranean diet was designed for members of groups 2 and 4. The BIS-11c was administered to determine the level of impulsiveness, and the KIDMED test was used to assess adherence to the Mediterranean diet. Results: The supplementation group showed a fairly significant decrease in the total BIS-11c (P = .049). Total cognitive score slightly decreased in the diet and supplementation groups. Only the control group showed a considerable decrease in the total motor score. Total nonplanning scores were lower in all groups after the intervention. Baseline and final BIS-11c scores were positively correlated with treatments (r > 0.9). Conclusion: An intake of 550 mg EPA fatty acid and 225 mg DHA fatty acid per day for 8 weeks is associated with less marked impulsive behaviour in children with ADHD. A Mediterranean diet may improve BIS scores, although our results are not conclusive in this population. (AU)

Test of Reliability and Validity of Impulsiveness Scale Among Married Chinese.

Introduction: The Brief Barratt Impulsiveness Scale (BBIS) can be used in large scale rapid assessments and improves data quality while reducing subject response burden. It has been verified to have good reliability and cross-cultural consistency in multiple countries. However, there are no tests of impulsivity for the Chinese married population. Aim: To investigate the applicability of the BBIS among the Chinese married population. Methods: The BBIS was administered to 664 married middle-aged adults (sample 1) for item analysis and exploratory factor analysis (EFA), and to 758 married middle-aged adults (sample 2) for confirmatory factor analysis (CFA). At the same time, the trait anger scale (TAS), the quality marriage index (QMI) and the emotion reactivity scale (ERS) are selected as the calibration standards to test the correlation validity of the calibration standards. Results: BBIS includes 8 items, which are composed of two dimensions of poor self-control and behavioral impulsivity; the two dimensions explained 68.10% of the total variance. CFA demonstrated that the fit index of the two-factor structure of the scale was good (χ2/df=2.315, RMSEA=0.042, RFI=0.971, CFI=0.989, NFI=0.982, IFI=0.990). The internal consistency reliability of each dimension and total scores were 0.824, 0.826 and 0.787, respectively. Total BBIS scores were significantly positively correlated with trait anger and emotional reactivity, and showed a significant negative correlation with marital quality. The Chinese version of BBIS had measurement equivalence between men and women. Conclusion: The BBIS has good reliability and validity in the Chinese married population, and the measurement results can be compared across groups between different genders, which can be used as a suitable tool for impulse related research.

Validation of a short Italian version of the Barratt Impulsiveness Scale (BIS-15) in non-clinical subjects: psychometric properties and normative data.

INTRODUCTION: The Barratt Impulsiveness Scale (BIS) is a questionnaire employed to measure impulsivity, which is associated with risky behaviors and mental disorders. We aimed to assess the psychometric properties of the BIS in the Italian general population and provide normative data for clinical use. MATERIALS AND METHODS: A cross-sectional survey methodology was employed to collect data. Then, 534 participants of different ages and educational levels completed the BIS, PHQ-9, GAD-7, and S-UPPS-P. We designed an ad hoc data-driven outcome checklist to identify which items deserved to be retained. Furthermore, internal consistency, convergent and divergent validity, and factorial structure were evaluated. A regression-based procedure was used to explore the influence of demographic variables on the BIS score and to provide adjusting factors and a sensitive cutoff. RESULTS: Item analysis suggested removing 15 items. Consequently, we tested the psychometric properties of a shorter version of the BIS (BIS-15). IRT test information functions indicated an almost identical measurement precision of the BIS-15 as compared to the original BIS. The BIS-15 demonstrated reliable internal consistency and good convergent and divergent validity. The PCA revealed a four-factor solution: "pure impulsivity," "planning and thinking," "lack of attention and concentration," and "impulsive buying." A significant effect of sex and years of education was found. Norms for the adjustment of raw scores were provided (cutoff = 37.39). CONCLUSIONS: The BIS-15 showed almost identical psychometric properties as compared with the original scale, reducing the administration time. Our norms may allow identifying individuals with impulsivity of clinical interest.

Psychometric Properties of the Turkish Version of the Barratt Impulsiveness Scale-Brief in Adolescents.

Introduction: Barratt Impulsiveness Scale-Brief (BIS-Brief) is a self-report scale that can be used to measure impulsivity in adolescents. In this study, it was aimed to determine the psychometric properties of the Turkish version of the BIS-Brief in clinical and non-clinical adolescent samples. Methods: The study included two groups of 116 psychiatric outpatients and 175 middle and high school students. For the re-test study, a small subgroup of the patient group (n=21) was re-applied BIS-Brief three weeks later. Socio-demographic data of the participants were collected. Aggression subscale of Childhood Behavior Checklist (CBCL), hyperactivity/impulsivity and anger control problems subscales of Conners-Wells' Adolescents Self-Report Scale-Long (CASS-L), and hyperactivity subscale of Conner's Parent Rating Scale-Short Form (CPRS-S) were administered. Results: The mean ages of the patient and control groups were 15.22±1.58 years and 15.16±1.86 years, respectively. There were 77 (66.4%) males in the patient group and 107 (61.1%) males in the control group. Cronbach's alphas for internal consistency were 0.78 (patient group) and 0.70 (control group). Three weeks test-retest reliability was 0.64 (patient group). We found a two-dimensional structure for the Turkish BIS-Brief. The BIS-Brief scores had a significant correlation with the scores of CBCL's aggression subscale (r=0.48; p<0.01), CASS-L's hyperactivity/impulsivity (r=0.45; p<0.01) and anger control problems subscales (r=0.45; p<0.01) and CPRS-S' hyperactivity subscale (r=0.21; p<0.01). Conclusion: Our findings suggest that the Turkish version of the BIS-Brief is a reliable and valid measure for clinical and non-clinical adolescent samples. In addition, the results show that the BIS-Brief has a two-dimensional model in contrast to the unidimensional structure of the original scale.

Role of White Matter Microstructure in Impulsive Behavior.

OBJECTIVE: Increased impulsivity is a hallmark trait of some neuropsychiatric illnesses, including addiction, traumatic brain injury, and externalizing disorders. The authors hypothesized that altered cerebral white matter microstructure may also underwrite normal individual variability in impulsive behaviors and tested this among healthy individuals. METHODS: Impulsivity and diffusion tensor imaging (DTI) data were collected from 74 healthy adults (32 women; mean age=36.6 years [SD=13.6]). Impulsivity was evaluated using the Barratt Impulsiveness Scale-11, which provides a total score and scores for three subdomains: attentional, motor, and nonplanning impulsiveness. DTI was processed using the Enhancing Neuro Imaging Genetics Through Meta Analysis-DTI analysis pipeline to measure whole-brain and regional white matter fractional anisotropy (FA) values in 24 tracts. RESULTS: Whole-brain total average FA was inversely correlated with motor impulsiveness (r=-0.32, p=0.007) and positively correlated with nonplanning impulsiveness (r=0.29, p=0.02); these correlations were significant after correction for multiple comparisons. Additional significant correlations were observed for motor impulsiveness and regional FA values for the corticospinal tract (r=-0.29, p=0.01) and for nonplanning impulsiveness and regional FA values for the superior fronto-occipital fasciculus (r=0.32, p=0.008). CONCLUSIONS: These results provide initial evidence that the motor and nonplanning subdomains of impulsive behavior are linked to specific white matter microstructural connectivity, supporting the notion that impulsivity is in part a network-based construct involving white matter microstructural integrity among otherwise healthy populations.

Impulsiveness in children with attention-deficit/hyperactivity disorder after an 8-week intervention with the Mediterranean diet and/or omega-3 fatty acids: a randomised clinical trial.

INTRODUCTION: The Barratt Impulsiveness Scale (BIS) is a self-administered instrument designed to assess the personality/behavioural construct of impulsiveness. Impulsiveness has been associated with several psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). This study assesses the progression of impulsive behaviour in children with ADHD after an 8-week dietary intervention with the Mediterranean diet and/or omega-3 fatty acid supplementation, by using a version of the 11-item BIS adapted for children (BIS-11c). METHODS: This cross-sectional study includes 60 children with ADHD from the region of Madrid, Spain. Participants were divided into 4 groups, with one control group and 3 intervention groups (Mediterranean diet; omega-3 supplementation; and Mediterranean diet plus omega-3 supplementation). A personalised Mediterranean diet was designed for members of groups 2 and 4. The BIS-11c was administered to determine the level of impulsiveness, and the KIDMED test was used to assess adherence to the Mediterranean diet. RESULTS: The supplementation group showed a fairly significant decrease in the total BIS-11c (P = .049). Total cognitive score slightly decreased in the diet and supplementation groups. Only the control group showed a considerable decrease in the total motor score. Total nonplanning scores were lower in all groups after the intervention. Baseline and final BIS-11c scores were positively correlated with treatments (r > 0.9). CONCLUSION: An intake of 550 mg EPA fatty acid and 225 mg DHA fatty acid per day for 8 weeks is associated with less marked impulsive behaviour in children with ADHD. A Mediterranean diet may improve BIS scores, although our results are not conclusive in this population.

Impulsivity, inhibition, and internet addiction in medical students of North of Iran.

Background: Internet addiction, a serious psychological disorder, has rapidly increased among students and caused substantial interpersonal impairments. On the other hand, some evidence has indicated that impulsivity is associated with addictive behaviors. Objectives: There are a few studies concerning the relationship between internet addiction and impulsivity in Iranian students. Therefore, this study aimed to evaluate the relationship between impulsivity and internet addiction in the medical students of Golestan University of Medical Sciences, Golestan, Iran, within 2020-2021. Methods: In a cross-sectional study, 260 medical students at Golestan University of Medical Sciences in 2021 completed demographic, Barratt Impulsiveness Scale, and Young questionnaires and participated in a Go/No-Go computer test. Based on Young test scores, the students were divided into three groups of normal users, at-risk users, and users requiring treatment and compared regarding impulsivity and inhibition ability. Data was analyzed using SPSS v 23. Results: The mean age of the participants was 24.16 years. The results showed a significant correlation between impulsivity and internet addiction (p = 0.001), which was established in all contextual indicators. A significant correlation was also shown between impulsivity and internet addiction (r = 0.602 and p = 0.001), both in male and female student. However, restraint index was correlated with internet addiction only in females (r = 0.187 and p = 0.033). Conclusion: Based on these findings, impulsivity increases alongside the rising of the internet addiction severity and does not influence by gender.

Comorbid impulsivity after one year of epilepsy surgery.

BACKGROUND: Psychiatric comorbidities in patients with drug-resistant epilepsy (DRE) are frequently observed before and after epilepsy surgery. Impulsivity, defined as behaviors that are poorly conceived, are also frequent among patients with epilepsy. The aim of this study was to determine the presence of comorbid impulsivity in patients with DRE after one year of epilepsy surgery. METHODS: Patients who underwent epilepsy surgery for DRE and completed the postsurgical assessment protocol one year after surgery were included. All patients underwent a presurgical protocol comprising of neurological, psychiatric, neuropsychological, video-EEG and MRI assessments. The psychiatric evaluation was performed before and one year after surgery using SCID-I, SCID-II, GAF scale of DSM IV, and Beck Depression Inventory II. One year after surgery, Barratt Impulsiveness Scale 11, and Engel classification of seizures, were administered. RESULTS: A total of 38 patients were included in this study, 21 women (55.3%) and 17 men (44.7%), mean age 36 years (SD = 9.4). Higher impulsivity was associated with a worse epilepsy seizure outcome (p < 0.05), one year after surgery. According to the multiple linear regression analysis, a worse epilepsy seizure outcome was associated with higher levels of nonplanning impulsivity (p < 0.05) (p < 0.05, ß -0.5, r2 0.25). The GAF score was negatively associated with motor score (p < 0.05, ß -0.584, r2 0.42) and with the total BIS-11 score (p < 0.05, ß -0.557, r2 0.39). CONCLUSIONS: Impulsivity has been associated with a worse post-surgical seizure outcome. Larger studies about impulsivity might confirm these preliminary findings.

Self-rated impulsivity in healthy individuals, substance use disorder and ADHD: psychometric properties of the Swedish Barratt impulsiveness scale.

BACKGROUND: Impulsivity is associated with several psychiatric disorders, including substance use disorders (SUD) and attention deficit hyperactivity disorder (ADHD). A widely used questionnaire to assess impulsivity is the Barratt Impulsiveness Scale (BIS), and the aim of the current study was to evaluate the psychometric properties of the Swedish version of the BIS (swe-BIS). METHODS: The original BIS was translated to Swedish and back-translated by an authorized translator. The swe-BIS was administered to healthy controls (n = 113), patients with alcohol use disorder (n = 97), amphetamine use disorder (n = 37) and attention deficit hyperactive disorder (ADHD; n = 26). A subset of subjects (n = 62) completed the swe-BIS twice within 1 week. Psychometric evaluation of the swe-BIS included assessment of different indices of reliability (internal consistency, test-retest and agreement) and validity (response processess, divergent and convergent). Confirmatory factor analyses (CFA) were performed to assess several indices of model fit in five different models based on previously suggested subscales. RESULTS: Cronbach's alpha for all swe-BIS items in the full sample was 0.89, ranging from 0.78-0.87 within the different subgroups. The Pearson test-retest correlation for total score was 0.78 (p < 0.001), with greater test-retest correlations within compared to across different subscales. The Bland-Altman plot indicated high level of agreement between test and retest. The healthy individuals had lower swe-BIS score compared to the patients (t(267.3) = - 8.6; p < 0.001), and the swe-BIS total score was also significantly different between each of the four participant groups (p < 0.01 for all group comparisons). Furthermore, swe-BIS had greater correlations with impulsivity related scales compared to non-impulsivity related scales. The CFA analyses indicated that while no suggested model showed an optimal fit, the best model fit indices was found for the 3-factor model. CONCLUSIONS: The swe-BIS was found to have good to excellent psychometric properties with respect to the assessed indices of reliability and validity, supporting use of the scale in clinical research in both healthy individuals and patients with SUD and ADHD.

Measuring Impulsivity in Greek Adults: Psychometric Properties of the Barratt Impulsiveness Scale (BIS-11) and Impulsive Behavior Scale (Short Version of UPPS-P).

INTRODUCTION: The aim of the present study was to validate the Barratt Impulsiveness Scale (BIS-11th version) scale as well as the short version of the Impulsive Behavior Scale (UPPS-P) in a population of Greek young adults. Secondly, we aimed at validating the BIS-11 in older adults. METHODS: 167 (Group 1) university students completed the Greek version of the BIS-11 (BIS-11-G) and the UPPS (UPPS-P-G) scales. Additionally, BIS-11-G was also administered to 167 (Group 2) cognitively intact older adults, to identify whether it could be used to measure impulsivity in an older adult population. RESULTS: Both scales had satisfactory internal reliability and test-retest reliability, as well as convergent validity in the young adult population. In regard to the factor structure, a principal component analysis (PCA) extracted two factors for the BIS-11-G in the young adult population and three factors in older adults, as well as three factors for the short UPPS-P-G in young adults. CONCLUSIONS: The BIS-11-G and the UPPS-P-G scales can be used to measure different aspects of impulsivity in the Greek population of different ages in research and clinical practice.

Impulsivity traits in eyelid myoclonia with absences.

PURPOSE: Eyelid myoclonia with absences (EMA) shares some clinical characteristics with juvenile myoclonic epilepsy (JME), in which impulsivity traits have been described. Aim of the study was to evaluate whether EMA patients could present a peculiar behavioural profile. METHODS: Patients with EMA, JME and healthy controls (HCs) were enrolled. Subjects with intellectual quotient <80 were excluded from the study. All the enrolled subjects underwent the Italian version of the Barratt Impulsiveness Scale (BIS-11) and the three dimensions of impulsivity (motor, attentional-cognitive and nonplanning impulsivity) were considered. RESULTS: Seventeen patients with EMA (12 females [70.6%], age 30.8±10 years), 29 patients with JME (17 females [58.6%], age 29.1±9.7 years) and 31 HCs (15 females [48.4%], age 27.6±5.8 years) were enrolled. Both EMA and JME patients presented a borderline significantly higher BIS total score than HCs (p=0.064). EMA patients presented a significantly higher BIS nonplanning subscore than JME patients and HCs (p=0.001). CONCLUSION: The study showed the presence of peculiar behavioral characteristics in EMA patients, slightly different from patients with JME.

Impulsivity Scale-12 and its utilization in alcohol use disorder.

INTRODUCTION: One of the core symptoms of alcohol use disorder (AUD) is impulsivity. The recently published study on the Impulsivity Scale 12 (IS-12) offers a promising tool to use in clinics working with clients with AUD due to its simplicity. IS-12 includes subscales related tocognitive impulsivity and behavioral impulsivity, which are related to different aspects of AUD symptomatology. The aim of the study was to adapt IS-12 to polish and test its utility in a sample of patients diagnosed with AUD. METHODS: Using a Confirmatory Factor Analysis, we compared the two-factor model of the Polish adaptation of the BIS-11 and the IS-12 on a sample of 615 patients diagnosed with AUD. Additionally, we explored the association between the IS-12's cognitive impulsivity and behavioral impulsivity subscales and depressive symptoms, AUD severity, and suicidal ideation using Structural Equation Modeling on a subsample of 450 patients with AUD. RESULTS: The IS-12 demonstrated a better model fit and good reliability compared to the BIS-11. Moreover, cognitive impulsivity predicted suicidal ideation, but not AUD severity, while behavioral impulsivity predicted AUD severity, but not suicidal ideation. Both subscales of IS-12 predicted depressive symptoms. CONCLUSION: Consistent with prior work, findings indicate that the second-order factor model of the BIS-11 had reliability issues and evidenced poor model fit. In contrast, the IS-12 demonstrated a satisfactory model fit and was predictive of clinical symptomatology. Thus, utilizing an easy tool, such as IS-12, might be beneficial for researchers and clinicians working with patients with AUD.

Association of Prefrontal Cortex Thinning with High Impulsivity in Healthy Adults.

OBJECTIVE: Studies have been conducted to identify brain structural alterations related to high impulsivity in psychiatric populations. However, research on healthy subjects is relatively less extensive. Therefore, we aimed to investigate the correlation between the cortical thickness of whole brain regions and the impulsivity level in a healthy population. METHODS: We included 100 healthy participants aged 19-65 years. Their T1-weighted magnetic resonance images and the 23-item Barratt Impulsiveness Scale (BIS) score were obtained. The patients were divided into high and low impulsivity groups according to the 75th percentile score of the BIS in the sample. The thickness of each cortical region was calculated using the FreeSurfer, and the difference in cortical thickness of the whole brain between the high and low impulsivity groups was analyzed using one-way analysis of covariance including age, sex, education level, and total intracranial cavity volume as covariates. RESULTS: The high impulsivity group showed significant cortical thinning in the left pars opercularis. The cortical thickness of the left pars opercularis significantly correlated negatively with the total, attention, and motor scores of the BIS scale. CONCLUSION: Our findings suggest that prefrontal cortex thinning may play an important role in the development of high impulsivity in healthy adults.

Deter the emotions: Alexithymia, impulsivity and their relationship to binge drinking.

INTRODUCTION: The relevance of both emotion processing and impulsivity to alcohol use and misuse is increasingly recognised, yet there is a scarcity of studies addressing their reciprocal interaction. The present study aimed to examine the role that difficulties in emotion processing and trait impulsivity play in explaining binge drinking pattern of alcohol use in student population. We looked at binge drinking, as it is a risk factor to later alcohol abuse and is a common alcohol drinking habit among students. Alexithymia (from Greek as "deter/repel emotions"), a difficulty in identifying and describing feelings in self and others is increasingly recognised as a feature of alcohol misuse. METHODS: One-hundred and seventy-four student alcohol drinkers were assessed for their drinking habits (Alcohol Use Questionnaire), as well as for alexithymia (Toronto Alexithymia Scale) and impulsivity trait (Barratt Impulsiveness Scale); facial emotional expression judgements were also tested. RESULTS: A direct relationships between, both, alexithymia and impulsivity, and binge drinking was found. When combined, trait impulsivity partially mediated the relationship between alexithymia and binge drinking. Facial emotional expression judgements also showed a relationship with binge drinking. CONCLUSIONS: These findings highlight the importance of both emotion processing and impulsivity in understanding binge drinking and indicate potential routes for prevention and intervention techniques, especially towards those who may be at risk of later alcohol abuse.

Suicide behavior is associated with childhood emotion dysregulation but not trait impulsivity in first episode psychosis.

Historically, research on suicide behavior has not included those experiencing first episode psychosis (FEP), hindering prevention efforts for this population. Emotion dysregulation and impulsivity represent two mechanisms that contribute to suicide, but these have not been examined in FEP. We hypothesize that the combination of trait impulsivity and childhood emotion dysregulation are associated with suicide behavior (SB) and ideation (SI) in those experiencing FEP. Participants were recruited from an Early Psychosis Program (N=80, ages 12-32, 65% male). Clinician ratings of symptoms and history of SI and SB were obtained at baseline. Participants also completed self-report measures of childhood emotion dysregulation and trait impulsivity. Regression analyses examined whether childhood emotion dysregulation and trait impulsivity individually or in combination were associated with SI and SB, and the severity of SI and SB. Childhood emotion dysregulation was significantly associated with a history of SB and its severity, but not SI. Attention impulsivity was associated with the severity of SI. However, other impulsivity types, and interactions were not associated with a history of SI or SB. This suggests childhood emotion dysregulation is a potential target for prevention of SB in FEP, while trait impulsivity may be less important in this effort.

Trait impulsivity correlates with active myoclonic seizures in genetic generalized epilepsy.

BACKGROUND: Juvenile myoclonic epilepsy (JME) is a common subtype of genetic generalized epilepsy (GGE) arising in adolescence and is often associated with executive function (EF) deficits. Some EF components like response inhibition have been extensively evaluated in JME, but few studies have focused upon trait impulsivity or compared between GGE subtypes. The aim of the present study was to compare the association of trait impulsivity in JME with other GGE subtypes. METHODS: Patients with GGE aged between 14 and 40 years (n = 137) were divided into those with JME (n = 92) and those with other GGEs (n = 45: 8 childhood absence epilepsy (CAE), 22 juvenile absence epilepsy (JAE), and 15 epilepsy with generalized tonic-clonic seizures only (EGTCS)). The study participants were recruited through medical records of the general population of Buskerud County and the neighboring municipalities, covering 477,000 people or 9.1% of Norway's total population. All participants underwent a clinical interview including the Barratt Impulsiveness Scale (BIS), an established measure of trait impulsivity. We controlled for other potential predictors of BIS score using analysis of covariance (ANCOVA). RESULTS: There were no differences between JME and other types of GGE for BIS scores, but the presence of myoclonic seizures within the last year, irrespective of GGE subtype, was independently associated with significantly increased behavioral impulsivity. CONCLUSIONS: This study demonstrates that trait impulsivity in GGE is most strongly related to the recent occurrence of myoclonic seizures rather than GGE subtype.