ABSTRACT
The ancient traditional Chinese drink Bian-Que Triple-Bean Soup made by fermentation (FTBS) of Lactococcus lactis subsp. lactis YM313 and Lacticaseibacillus casei YQ336 is a potential functional drink. The effect of fermentation on the flavor and biological activity of FTBS was evaluated by analyzing its chemical composition. Five volatile flavors were detected in modified FTBS. Fermentation decreased the proportion of nonanal (beany flavor substances) but significantly increased the total flavone contents, phenol contents and many bioactive small molecule substances in FTBS. The changes of these substances led to the significant improvement of FTBS sensory evaluation, antioxidant activity and prebiotic potential. This research provides a theoretical basis for the application of Lactic acid bacteria (LAB) in the fermentation of edible plant-based foods and transformation from traditional food to industrial production.
ABSTRACT
Bian Que rose from a common human being to animmortal worshipped by the people since Han dynasty. In the Song Dynasty, Emperor Renzong of Song bestowed on Bian Que ShenYing Hou(Marquis), then ShenYing Gong(Duke), and built a temple for Bian Que. The Imperial Medical Service of Song enacted a law in which he was the god of the medical profession and a primary worship, with Qi Bo accompanied.After the downfall of the Northern Song dynasty, in the same way, Emperor Gaozong of Song also built the temple for Bian Que in Lin'an, the capital of Southern Song. And in the north, the physicians in Jin dynasty still worshiped Bian Que.But when it came to Yuan dynasty, The Three Sovereigns (Fu Xi, Shennong, Yellow Emperor) were regarded the Fathers of physicians, with ten famous physicians as subordinate worship, Bian Que was not among the them.At first, Ming dynasty followed Yuan, until the Jiajing reign, Bian Que became a subordinate worship, belonged to the new added 18 famous physicians. The Qing dynasty basically followed the Ming.In conclusion, Bian Que was considered as one of inheritors of medicine, and downgraded from primary worship to subordinate worship during the Ming and Qing dynasties.
ABSTRACT
Among the medical texts excavated in 2012-2013 from the Han Dynasty tomb at Tianhui township in Sichuan province, we found a collection on the treatment of 60 ailments. Under each ailment, we found one or more formulas, for a total of 106 formulas. The authors of this paper compiled and analyzed these texts based on the original bamboo slips and named this collection with the title Methods for Blending Decoctions to Treat 60 Ailments because the content was focused on blending and making medicinal formulas, and also due to the historical connections with the texts the Record of the Court Scribe, "Biography of Bian Que and Cang Gong". For these reasons, this title was determined, where "blending decoctions" mean "blending and harmonizing medicines optimally in preparation for decocting". The Tianhui texts preserve ancient forms of medicinal formulas, including some once believed to be lost, such as î"grain decoctions"î, "fermented alcohol decoctions", and "fiery decoctions". Based on the historical evidence, we can now ascertain that this text is the "Blending Formulas and Making Decoctions" mentioned in the Record of the Court Scribe written by Cang Gong. Moreover, the medical texts, Canon Formulas in Decoction Form (from the book of Han Dynasty) and the Imperial Pharmacy Formulas to Benefit the People in Song Dynasty are both of this genre of medical literature. The Tianhui text is therefore a representative of this genre of literature in the Western and eastern Han, acting as a key link between early medical formula books and later formula books.
Subject(s)
Drug Compounding/methods , Drugs, Chinese Herbal , Medicine, Chinese Traditional , Records , China , Ethanol , Manuscripts as TopicABSTRACT
Among the medical texts excavated in 2012-2013 from the Han Dynasty tomb at Tianhui township in Sichuan province, we found a collection on the treatment of 60 ailments. Under each ailment, we found one or more formulas, for a total of 106 formulas. The authors of this paper compiled and analyzed these texts based on the original bamboo slips and named this collection with the title Methods for Blending Decoctions to Treat 60 Ailments because the content was focused on blending and making medicinal formulas, and also due to the historical connections with the texts the Record of the Court Scribe, "Biography of Bian Que and Cang Gong". For these reasons, this title was determined, where "blending decoctions" mean "blending and harmonizing medicines optimally in preparation for decocting". The Tianhui texts preserve ancient forms of medicinal formulas, including some once believed to be lost, such as "grain decoctions", "fermented alcohol decoctions", and "fiery decoctions". Based on the historical evidence, we can now ascertain that this text is the "Blending Formulas and Making Decoctions" mentioned in the Record of the Court Scribe written by Cang Gong. Moreover, the medical texts, Canon Formulas in Decoction Form (from the book of Han Dynasty) and the Imperial Pharmacy Formulas to Benefit the People in Song Dynasty are both of this genre of medical literature. The Tianhui text is therefore a representative of this genre of literature in the Western and eastern Han, acting as a key link between early medical formula books and later formula books.
Subject(s)
China , Drug Compounding , Methods , Drugs, Chinese Herbal , Ethanol , Manuscripts as Topic , Medicine, Chinese Traditional , RecordsABSTRACT
Objective:To explore the clinical effect of "Bian Que flying rescue" system for patients with chest pain in pre-hospital care.Methods:160 patients with acute chest pain were randomly divided into observation groups (80 cases) and control group (80 cases). The patients of observation group received the treatment of "Bian Que flying rescue" system and the patients of control group received the routine pre-hospital emergency measures. A series of indicators including the diagnosis time of pre-hospital, the time span between attack and beginning treatment, clinical curative effect, occurrence of complication and hospital stay time were compared and recorded.Results:The diagnosis time of pre-hospital, diagnosis time of intra-hospital and the time between attack and beginning treatment of observation group were significantly shortened, and the differences of these indicators between two groups were significant (t=14.095,t=9.997,t=4.230,P<0.05), respectively. The numbers of the attack of various complication of observation group were significantly reduced, and the differences of cardiac failure, cardiogenic shock, malignant arrhythmia and myocardial infarction between the two groups were statistically significant (x2=10.230,x2=9.141, x2=5.223,x2=5.096,P<0.05).And the prognosis of observation group was significantly enhanced, and the number of die in one week was significantly reduced, and the differences of these indicators between the two groups were significantly(x2=12.172,P<0.05). Besides, the time of hospital stay and the total cost of hospital stay of observation group were, respectively, significantly shortened and decreased, and the left ventricular ejection fraction (LVEF) of observation group was significantly increased. And the differences of all of these indicators between the two groups were statistically significant(t=4.022,t=4.495,t=9.047,P<0.05).Conclusion: "Bian Que fling rescue" system which was applied in the first aid outside of hospital for patients with chest pain can significantly improve the success rate of rescue, and reduce case fatality rate and the occurrences of complications including congestive heart failure and cardiogenic shock, and shorten the time of therapy, and increase economic efficiency of hospital. It has a certain clinical application value.
ABSTRACT
Objective:To explore the clinical effect of "Bian Que flying rescue" system for patients with chest pain in pre-hospital care.Methods:160 patients with acute chest pain were randomly divided into observation groups (80 cases) and control group (80 cases). The patients of observation group received the treatment of "Bian Que flying rescue" system and the patients of control group received the routine pre-hospital emergency measures. A series of indicators including the diagnosis time of pre-hospital, the time span between attack and beginning treatment, clinical curative effect, occurrence of complication and hospital stay time were compared and recorded.Results:The diagnosis time of pre-hospital, diagnosis time of intra-hospital and the time between attack and beginning treatment of observation group were significantly shortened, and the differences of these indicators between two groups were significant (t=14.095,t=9.997,t=4.230,P<0.05), respectively. The numbers of the attack of various complication of observation group were significantly reduced, and the differences of cardiac failure, cardiogenic shock, malignant arrhythmia and myocardial infarction between the two groups were statistically significant (x2=10.230,x2=9.141, x2=5.223,x2=5.096,P<0.05).And the prognosis of observation group was significantly enhanced, and the number of die in one week was significantly reduced, and the differences of these indicators between the two groups were significantly(x2=12.172,P<0.05). Besides, the time of hospital stay and the total cost of hospital stay of observation group were, respectively, significantly shortened and decreased, and the left ventricular ejection fraction (LVEF) of observation group was significantly increased. And the differences of all of these indicators between the two groups were statistically significant(t=4.022,t=4.495,t=9.047,P<0.05).Conclusion: "Bian Que fling rescue" system which was applied in the first aid outside of hospital for patients with chest pain can significantly improve the success rate of rescue, and reduce case fatality rate and the occurrences of complications including congestive heart failure and cardiogenic shock, and shorten the time of therapy, and increase economic efficiency of hospital. It has a certain clinical application value.
ABSTRACT
Bian-que was,according to legend,the earliest known Chinese physician(ca.500 B.C.),and was regarded as the founder of TCM Theory in China.He possessed outstanding diagnostic techniques,and high-minded medical morality as well.Thorough excavation and exploration of his medical ethics thought is not only helpful to enrich and carry forward TCM culture,but also of great practical ethical values in constructing TCM morality system.
ABSTRACT
The authors advocate that Bian Que lived iil the end of Spring - Autumn Period. Although personal writing first appeared in the Warring States; there were medical officials in all the States, the achievements of whom were examined by their the authority based on their own original records. Moreover. Chang Sangjun. Bian Que's tutor, "left all his secret books on recipes to Bian Que". Hence, the likelihood of appearance of medical monographs in Bian Que's age is very high. His discussions on morbid pulse and normal pulse were also inherited and developed.
