Go-Game Image Recognition Based on Improved Pix2pix.

Go is a game that can be won or lost based on the number of intersections surrounded by black or white pieces. The traditional method is a manual counting method, which is time-consuming and error-prone. In addition, the generalization of the current Go-image-recognition methods is poor, and accuracy needs to be further improved. To solve these problems, a Go-game image recognition based on an improved pix2pix was proposed. Firstly, a channel-coordinate mixed-attention (CCMA) mechanism was designed by combining channel attention and coordinate attention effectively; therefore, the model could learn the target feature information. Secondly, in order to obtain the long-distance contextual information, a deep dilated-convolution (DDC) module was proposed, which densely linked the dilated convolution with different dilated rates. The experimental results showed that compared with other existing Go-image-recognition methods, such as DenseNet, VGG-16, and Yolo v5, the proposed method could effectively improve the generalization ability and accuracy of a Go-image-recognition model, and the average accuracy rate was over 99.99%.

Three Cases of Caseous Calcification of Mitral Annulus (CCMA) / 日本心臓血管外科学会雑誌

Caseous calcification of mitral annulus (CCMA) is rare variant of mitral annular calcification (MAC). There is no clear consensus on the optimal management for CCMA. However, patients with CCMA have high risk of embolic strokes. We performed drainage and debridement in 3-cases of CCMA. All patients had a history of chronic kidney disease (CKD), and two of the three patients were undergoing hemodialysis. If a calcified mass at the mitral valve annulus is observed, especially in hemodialysis patients, CCMA should be recognized.

Caseous calcification of posterior mitral annulus: a forgotten benign condition mimicking atrial mass.

Caseous calcification of posterior mitral annulus is considered a variant of mitral annular calcification and accounts for less than 1% cases of mitral valve calcification (MAC). Usually benign and asymptomatic and has typical features on imaging studies but may contribute to unnecessary investigations and interventions in some patients, transthoracic echocardiography (TTE) is most useful tool in the diagnosis of this condition, whether it is associated with increased risk of atherosclerosis is unknown. We are presenting a case of caseous calcification of posterior mitral annulus that is discovered during elective coronary angiography in a patient with extensive history of coronary heart disease who had abnormal stress test.

Caseous calcification of the mitral annulus: a rare entity confirmed by cardiovascular magnetic resonance imaging.

Caseous calcification of the mitral annulus (CCMA) is a rare variant of mitral annulus calcification which presents as a semilunar echodense mass with smooth borders and central areas of echolucency. It is an under-recognized benign entity and can be misdiagnosed for a number of pathologies including tumors, abscesses and thrombi. We present a representative CCMA case and highlight its typical appearance on magnetic resonance imaging.

Electricity Generation by Shewanella decolorationis S12 without Cytochrome c.

Bacterial extracellular electron transfer (EET) plays a key role in various natural and engineering processes. Outer membrane c-type cytochromes (OMCs) are considered to be essential in bacterial EET. However, most bacteria do not have OMCs but have redox proteins other than OMCs in their extracellular polymeric substances of biofilms. We hypothesized that these extracellular non-cytochrome c proteins (ENCP) could contribute to EET, especially with the facilitation of electron mediators. This study compared the electrode respiring capacity of wild type Shewanella decolorationis S12 and an OMC-deficient mutant. Although the OMC-deficient mutant was incapable in direct electricity generation in normal cultivation, it regained electricity generation capacity (26% of the wide type) with the aid of extracellular electron mediator (riboflavin). Further bioelectrochemistry and X-ray photoelectron spectroscopy analysis suggested that the ENCP, such as proteins with Fe-S cluster, may participate in the falvin-mediated EET. The results highlighted an important and direct role of the ENCP, generated by either electricigens or other microbes, in natural microbial EET process with the facilitation of electron mediators.

Tailoring strain construction strategies for muconic acid production in S. cerevisiae and E. coli.

There is currently a strong interest to derive the biological precursor cis,cis-muconic acid from shikimate pathway-branches to develop a biological replacement for adipic acid. Pioneered by the Frost laboratory this concept has regained interest: Recent approaches (Boles, Alper, Yan) however suffer from low product titres. Here an in silico comparison of all strain construction strategies was conducted to highlight stoichiometric optimizations. Using elementary mode analysis new knock-out strategies were determined in Saccharomyces cerevisiae and Escherichia coli. The strain construction strategies are unique to each pathway-branch and organism, allowing significantly different maximum and minimum yields. The maximum theoretical product carbon yields on glucose ranged from 86% (dehydroshikimate-branch) to 69% (anthranilate-branch). In most cases a coupling of product formation to growth was possible. Especially in S. cerevisiae chorismate-routes a minimum yield constraint of 46.9% could be reached. The knock-out targets are non-obvious, and not-transferable, highlighting the importance of tailored strain construction strategies.