Gonadotropin-releasing hormone agonist contributes to the successful implementation of in vitro fertilization in a patient with cervical endometriosis: a case report.

This is a case report of a nulliparous young woman who suffered from prolonged menstruation and infertility for 1 year. Magnetic resonance imaging and a transvaginal ultrasound examination revealed cervical endometriosis. Treatment with a gonadotropin-releasing hormone agonist stopped the abnormal bleeding and enabled investigators to conduct a hysterosalpingogram, which suggested bilateral hydrosalpinx. Subsequently, the patient underwent in vitro fertilization and had a live birth after frozen-thawed embryo transfer with gonadotropin-releasing hormone agonist pretreatment.

A Rare Case of the Cervical Endometriosis and Overview of the Literature.

Cervical endometriosis is an uncommon form of endometriosis that is frequently diagnosed incidentally during histopathological evaluation of a hysterectomy or cervical biopsy specimens. Although some cases may be asymptomatic, the symptoms in some patients range from life-threatening hemorrhage to severe chronic pelvic pain. In asymptomatic patients, no further intervention might be required apart from observation and follow-up; however, patients with significant symptoms will require surgery. Primary cervical endometriosis is defined as presence of endometrial tissue on the anterior lip of the cervix, limited to the cervix surface and not extending below the squamous epithelium. Secondary cervical endometriosis is more common than the primary type and describes the disease extensions from the pelvis, or usually the rectovaginal septum. Superficial endometriosis is usually diagnosed by fine-needle aspiration, colposcopy, and cervical biopsy after a routine cervical smear, as endometrial cells detected during a PAP smear may be mistakenly removed as atypical glandular cells. Deep endometriosis may cause pelvic pain, vaginal bleeding, and spotting. In this case report, we present a rare case of cervical endometriosis, characterized by pelvic pain and menstrual irregularity, with endometrioma and adenomyosis, confirmed by histopathological evaluation of the specimen. A summary of the cervical endometriosis cases overview has been made to describe the changing clinical landscape of this rare condition.

Coexistence of cervical endometriosis with premalignant and malignant gynecological pathologies: report on a series of 27 cases.

Although cervical endometriosis represents a rare condition, there is evidence that implicates a complex interaction with other gynecological pathologies. This study aims to highlight this entity and further to explore the impact of oncological pathology of female genital tract on patients with cervical endometriosis. We retrospectively investigated the medical and pathological reports of 27 cases with cervical endometriosis, which were diagnosed by tissue biopsy. The results of the study show a relationship between CIN (cervical intraepithelial neoplasia) cases 19/27 (70percent) and cervical endometriosis. CIN I was more frequently found compared to patients with CIN II and CIN III. Furthermore, a high prevalence of HPV (human papilloma virus) was confirmed. Out of 27 patients, 2 cases with cervical (7.4percent), 2 with endometrial (7.4percent) and 3 with ovarian cancer (11.1percent) were detected. We confirmed the coexistence of more than one malignant gynecological pathology with cervical endometriosis in four cases (14.8percent). To conclude, cervical endometriosis is a rare disease co-existing considerably with premalignant and malignant gynecological conditions according to our data. Although the pathophysiology and genetics of cervical dysplasia is well delineated, further research is needed to establish the association between cervical endometriosis and gynecological premalignant and malignant pathology.

[CO2 laser ablation of cervical endometrioid lesions - treatment efficacy evaluation]. / Ablacja zmian endometrialnych szyjki macicy laserem CO2 ­ ocena skutecznosci leczenia.

Endometriosis affects 10-15% of the female population of childbearing potential. Endometrioid lesions of the cervical surface are a rare manifestation of the disease. There are various complaints related to this particular form of endometriosis, making the diagnosis challenging. Treatment also raises problems, as widely available and used therapeutic methods often prove to be ineffective. AIM: The aim of the study was to evaluate the efficacy of CO2 laser beam ablation in a group of patients with cervical endometriosis lesions. MATERIALS AND METHODS: This paper presents a summary of cervical endometriosis treatment efficacy in a group of 15 patients who have undergone CO2 laser ablation between May 2016 and April 2019. The majority of patients have already been treated for cervical endometriosis, using cryotherapy, electrocoagulation, curettage and loop electrosurgical excision procedure (LEEP). All patients, following preliminary colposcopy verification and exclusion of malignancies, have undergone CO2 laser ablation of endometrioid cervical lesions. A visual evaluation of the cervix was performed before treatment, directly after the procedure, as well as 4-6 weeks after the procedure, and subsequently every 6-8 months. RESULTS: This paper presents a summary of cervical endometriosis treatment efficacy in a group of 15 patients who have undergone CO2 laser ablation between May 2016 and April 2019. The majority of patients have already been treated for cervical endometriosis, using cryotherapy, electrocoagulation, curettage and loop electrosurgical excision procedure (LEEP). All patients, following preliminary colposcopy verification and exclusion of malignancies, have undergone CO2 laser ablation of endometrioid cervical lesions. A visual evaluation of the cervix was performed before treatment, directly after the procedure, as well as 4-6 weeks after the procedure, and subsequently every 6-8 months. CONCLUSIONS: Cervical endometriosis is a rare manifestation of the diseases, with variable symptoms. It can become a diagnostic challenge, as endometrioid lesions may be confused with cervical malignancies, as well as a therapeutic one, as many of the methods employed prove unsuccessful. Laser ablation of endometrioid cervical lesions seen to be a minimally invasive, safe and effective treatment method that can be offered in an outpatient setting.

A Case of Cervical Endometriosis with Cystic Change / 대한산부인과학회잡지

Cervical endonetriosis with cystic change is extremely rare lesion. We experienced onecase of cervical endometriosis in 33 year old woman, who had no symptoms, so we reprot thecase and brief review of literatures.