ABSTRACT
Decoction pieces are the crude materials of Chinese medicinal granule, herbal decoction, and Chinese patent medicine. Its quality directly affects the quality of the three major traditional Chinese medicine products. As the intermediate link of "traditional Chinese medicinal materials-Decoction pieces-Chinese patent medicine" industry chain, the quality is very important. However, the quality control of Chinese materia medica (CMM) products has been dominated by traditional Chinese medicinal materials in recent decades. Though the quality control of Chinese herbal pieces is paid gradually more attention in the industry, it still can not reflect its own characteristics. The lack of scientificity, effectiveness, and rationality seriously affects the healthy development of CMM industry. Academician Chang-xiao Liu first proposed the new concept of "quality marker of CMM" in 2016, which caused a strong reaction. This paper reviewed and analyzed the current situation of the quality standard of CMM industry in detail, combined the research approach of "quality marker of CMM" with the characteristics of decoction pieces, in order to form the new idea of "quality marker of decoction pieces". The purpose is to stimulate thinking and resonance of the experts in the field of Chinese herbal pieces, to promote the improvement of quality control methods of Chinese herbal pieces, and to ensure the rapid development of CMM products industry.
ABSTRACT
Objective: To identify the Chinese medicinal granule (CMG) by measuring IR fingerprints. Methods : 12 species drugs were extracted with butanone respectively and then the obtained extracts were measured by the FT-IR spectrometer. Results : By IR fingerprint of 12 kinds of CMG, we found that different batches of the same CMG had a stable and repeatable fingerprint. Conclusion : By using IR fingerprint, CMG can be identified. It provides a rapid monitoring for drug identification and quality control.
ABSTRACT
AIM: To identify the Chinese medicinal granule by measuring IR fingerprints. METHODS: 13 kinds of granules were extracted with butanone respectively and then the obtained extracts were measured with the FT IR spectrometer. RESULTS: By IR fingerprint of 13 kinds of granules drugs, different batches of the same crude drug had a stable and repeatable fingerprint. CONCLUSION: By using IR fingerprint, Chinese medicinal granule can be identified and provides a rapid method for drug identification and quality control.
