Comportamiento de kit de detección de Chlamydia trachomatis en pacientes infectados y sometidos a terapia antimicrobiana / Behavior of the kit of Chlamydia trachomatis on infected patients undergoing antibiotic therapy

Se realiza un estudio en el laboratorio de microbiología del Hospital General Docente Agostinho Neto, en el período enero - marzo del presente año, con el objetivo de evaluar el comportamiento de la prueba rápida CHLAMY-CHECK-1 en pacientes infectadas y sometidas a terapia antimicrobiana. El universo de estudio está formado por 20 mujeres que resultaron positivas a la prueba de determinación rápida. Los resultados fueron que las pacientes con tratamiento adecuado que se realizaron el segundo kit inmediato a la culminación del tratamiento resultaron positivas, las pacientes con tratamiento adecuado y segundo kit realizado después del mes resultaron negativas. Se concluye que el ensayo inmunocromatográfico realizado no diferencia si el antígeno está metabólicamente activo o inactivo, por lo que aquellas pacientes que hayan recibido correctamente el tratamiento antimicrobiano deben esperar un plazo no menor a un mes para realizar un nuevo diagnóstico. La doxiciclina mostró patrones adecuados de sensibilidad(AU)

A study was performed in the microbiology laboratory at the General Teaching Hospital Dr Agostinho Neto, from January to March this year, in order to evaluate the behavior of the rapid test CHLAMY-CHECK-1 on infected patients and subjected to antimicrobial therapy. The study group consists of 20 women who were positive for rapid determination test. As a result, the patients with adequate treatment in which were applied the second immediate treatment kit were positive, patients with appropriate treatment and second kit made after the month were negative. As a conclusion that the immunochromatographic trial no determine if the antigen is metabolically active or inactive, so that those patients who have successfully received antimicrobial therapy should expect no less than one month to make a new diagnosis. Doxycycline showed good sensitivity patterns

Prevalencia de Chlamydia trachomatis y Neisseria gonorrhoeae en adolescentes chilenas / Rates of Chlamydia trachomatis and Neisseria gonorrhoeae in Chilean adolescents

Background: Chlamydia trachomatis and Neisseria gonorrhoeae are common sexually transmitted diseases among young women and little has been doing to study them in Chilean adolescents. Aim: Determine the rates of C trachomatis and N gonorrhoeae in Chilean young women. Material and methods: Urine samples were obtained from 203 sexually active females under 25 year-old, who attended hospitals from either high or low-income areas in Chile's capital, Santiago. C trachomatis and Ngonorrhoeae were detected by nucleic acid amplification testing. Results: Seven percent of samples were positive for C trachomatis. AU samples were negative for N gonorrhoeae. Among pregnant women, 19 percent of samples were positive for C trachomatis, while non-pregnant women were positive on 5.5 percent (p =0.04). Systematic use of barrier contraception was referring by 12 percent of women. AU of the latter was free of C trachomatis. No association was observing between age, number of sexual partners, age of first sexual intercourse, and presence of uro-gynecological symptoms, socioeconomic status and the rate of C trachomatis. Conclusions: Seven percent of this group of Chilean young women was infected with C trachomatis. The figure rises to 19 percent if pregnant. Surveillance and screening programs should been implemented to prevent sequels on this vulnerable population.