ABSTRACT
Floppy eyelid syndrome is rarely diagnosed nowadays. Most patients remain without the correct diagnosis for a long time, which means they do not receive adequate treatment. This syndrome is known to be accompanied by many concomitant clinical manifestations complicating the diagnostic search. It should be included in the diagnostic search algorithm in patients with chronic conjunctivitis, abnormal eyelid position, point keratopathy. This review presents the modern understanding of characteristic clinical features, associated conditions, as well as information about the pathogenesis of this syndrome.
Subject(s)
Conjunctivitis , Corneal Diseases , Eyelid Diseases , Conjunctivitis/diagnosis , Conjunctivitis/etiology , Eyelid Diseases/diagnosis , Eyelid Diseases/etiology , Eyelids , Humans , SyndromeSubject(s)
Bacillus thuringiensis/isolation & purification , Conjunctivitis, Bacterial/diagnosis , Eye Infections, Bacterial/diagnosis , Gram-Positive Bacterial Infections/diagnosis , Administration, Ophthalmic , Anti-Bacterial Agents/therapeutic use , Conjunctivitis, Bacterial/drug therapy , Conjunctivitis, Bacterial/microbiology , Dexamethasone/therapeutic use , Drug Therapy, Combination , Eye Infections, Bacterial/drug therapy , Eye Infections, Bacterial/microbiology , Glucocorticoids/therapeutic use , Gram-Positive Bacterial Infections/drug therapy , Gram-Positive Bacterial Infections/microbiology , Humans , Male , Middle Aged , Moxifloxacin/therapeutic use , Ophthalmic Solutions , Recurrence , Tobramycin/therapeutic useABSTRACT
Molluscum contagiosum (MC) is a viral infection of the skin and mucosal tissues characterized by skin-colored or transparent round nodules with a dimple or pit in the center. The infection is caused by a DNA poxvirus called the MC virus. Although MC generally occurs in children, it has also been reported in immunocompromised and atopic patients. The virus is transmitted by skin contact or sexual intercourse. The lesions disappear spontaneously within several months in most cases. However, excision, cryotherapy, cauterization, topical chemical and antiviral agents, and/or oral cimetidine are used in refractory cases or to accelerate the healing process. Herein, we discussed the clinical findings and our treatment of two patients with unilateral chronic conjunctivitis associated with eyelid MC lesions in light of the literature.
ABSTRACT
Objective To observe clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis.Methods 96 patients with chronic conjunctivitis from ophthalmology department from January 2015 to October 2016 were grouped two groups by draw method,each with 48 cases.The control group was treated with ofloxacin eye drops,and observation group was treated with Zhenzhumingmu eye drops combing with ofloxacin eye drops.Related indicators are analyzed in two groups.Results ①Effective rate of observation group was 87.50%,higher than control group with 66.67%(P<0.05).②Dry eye, eye itching, eye fatigue and foreign body sensation score of observation group were (1.01±0.24),(0.93±0.22),(0.85±0.18),(0.81±0.25)points,lower than control group(1.46±0.30),(1.39±0.25),(1.16±0.21),(1.22±0.29)(all P<0.05).③Eye discomfort proportion of observation group was 12.50%, higher than control group 8.33%,but the difference was not statistically significant.Conclusion Zhenzhumingmu eye drops has exact curative effect in treatment of chronic conjunctivitis,can improve the symptoms and has high security.
ABSTRACT
CLINICAL CASE: The case is presented of a 43 year-old male patient with chronic follicular conjunctivitis, negative bacterial serology, and refractory to local treatment. The incisional biopsy performed showed to be consistent with reactive lymphoid hyperplasia. A year later, a new incisional biopsy showed follicular lymphoma, with no systemic involvement, and he was treated with local radiotherapy. DISCUSSION: When a chronic follicular conjunctivitis is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis that can range from chronic inflammation, reactive lymphoid hyperplasia to lymphoma. Follicular lymphoma is rare among conjunctival lymphomas, and the staging is indispensable for the correct therapeutic approach.
Subject(s)
Conjunctival Neoplasms/diagnosis , Conjunctivitis/diagnosis , Lymphoma, Follicular/diagnosis , Adult , Conjunctiva , Diagnosis, Differential , Humans , MaleABSTRACT
Conjunctivitis is the most common cause of red eye in primary care. The 3 most common types of conjunctivitis are viral, allergic, and bacterial, and they can present in either acute or chronic forms; the age of the patient, time of year and physical examination findings are paramount to distinguish the different types of conjunctivitis. Distinguishing between acute viral and bacterial conjunctivitis remains difficult. Patients with prolonged symptoms, poor response to initial management, or evidence of severe disease should be referred to ophthalmology for consultation.
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Conjunctivitis/physiopathology , Primary Health Care , Acute Disease , Administration, Oral , Administration, Topical , Age Factors , Anti-Allergic Agents/therapeutic use , Anti-Bacterial Agents/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Antiviral Agents/therapeutic use , Chronic Disease , Conjunctivitis/diagnosis , Conjunctivitis/drug therapy , Conjunctivitis/microbiology , Conjunctivitis, Allergic/drug therapy , Diagnosis, Differential , Humans , Physical Examination , Referral and Consultation , SeasonsABSTRACT
O Tracoma é uma doença milenarmente conhecida e que persiste como causa de cegueira entre nós. As autoras chamam a atenção para os fatores relacionados com a transmissão, apresentam dados históricos e de distribuição da doença no Brasil e no mundo, comentam sobre o agente, os sinais e os sintomas desta conjuntivite crônica. Ainda reforçam a necessidade de capacitar os profissionais para o diagnóstico, o que possibilitará a detecção e tratamento. O reflexo destas atitudes será a contribuição para a eliminação desta importante causa de cegueira do nosso meio.
Trachoma is a disease known thousand years ago and still as a potential blindness disease all over the world. The authors call attention to the factors related with the transmission, present historical data and distribution of the disease in Brazil and in the world, comment on the agent, the signs and symptoms of this chronic conjunctivitis. Still, reinforce the need to enable professionals for the diagnosis, detection and treatment.The reflection of these attitudes will be the contribution to the elimination of this important disease as a blindness cause among us.
Subject(s)
Humans , Trachoma/complications , Trachoma/history , Trachoma/epidemiology , Blindness/etiology , Poverty , Socioeconomic Factors , Brazil/epidemiology , Chlamydia trachomatis , Sanitation , Trachoma/diagnosis , Trachoma/drug therapy , Blindness/prevention & control , Blindness/epidemiology , Hygiene , Health Education , Azithromycin/therapeutic use , Anti-Bacterial Agents/administration & dosageABSTRACT
PURPOSE: We report six cases of histologically diagnosed conjunctival MALT (mucosa-associated lymphoid tissue)oma. Presenting symptoms were eyelid swelling, foreign body sensation, lid mass, injection and itching sensation. PATIENTS AND METHODS: Six patients with conjunctival MALToma were followed. Clinical progress and biopsy result were reviewed periodically. RESULTS: The conjunctival MALToma seemed to be localized and slowly progressive. Although the conjunctival MALToma is known to be well responsive to radiotherapy, two of three patients who received radiotherapy revealed to have remnant lymphoma cells histologically in conjunctival biopsy. In addition, chemotherapy did not have curative effect in any of the patients. CONCLUSIONS: Therefore, we are doubtful for the necessity of active treatment in MALTomas of the conjunctiva.
Subject(s)
Humans , Biopsy , Conjunctiva , Drug Therapy , Eyelids , Foreign Bodies , Lymphoma , Pruritus , Radiotherapy , SensationABSTRACT
Ocular cicatricial pemphigoid isa chronic, progressive disease characterized by cicatricial shrinkage of the conjunctiva, entropion, trichiasis, xerosis, and finally reduced vision from corneal opacification. It is a relatively rare, autoimmune disease. In the early stages, it can be easily overlooked as simple chronic conjunctivitis, so it can be untreated. We report a case of ocular cicatricial pemphigoid that resulted in significant morbidity. We were able to control the progression of cicatrization with aggressive immunosuppressive therapy.
Subject(s)
Autoimmune Diseases , Cicatrix , Conjunctiva , Conjunctivitis , Entropion , Pemphigoid, Benign Mucous Membrane , Pemphigoid, Bullous , Trichiasis , Vision, LowABSTRACT
We experienced chronic relapsing central corneal ulcer and chronic conjunctivitis with mucoid discharge. Both patients were transfered to our hospital because of no improvement with long term treatment of broad spectrum antibiotics topically and systemically Specimens from corneal scraping and conjunctival mucoid discharge were examined with calcofluor white staining method. We could find a narrow rim of light green colored cystic wall and orange red colored cytoplasm in dark field fluorescent microscopy in both cases, and those were diagnosed as Acnthamoebic cyst by pathologist. We couldn't find any report about ocular Aanthamoeba infections in Korea. To our knowledge, this is the first case report about ocular Acanthamoebic infections in Korea.
