County land use carbon emission and scenario prediction in Mianyang Science and Technology City New District, Sichuan Province, China.

The role of carbon emissions resulting from land use change in the compilation of national greenhouse gas emission inventories is of paramount significance. This study is centered on the Mianyang Science and Technology City New Area located in Sichuan Province, China. We used the CLUE-S model and Sentinel-2A remote sensing data from 2017 to simulate and validate land use changes in 2022. Based on this validation, we established three simulation scenarios: a baseline scenario, an agricultural development scenario, and a construction development scenario. Using remote sensing data from 2022, we projected the land use for 2030. We also used CO2 concentration data collected in 2022 and 2023, processed the data using ArcGIS and Python, and conducted a quantitative analysis of carbon emissions under each scenario. Ultimately, the accuracy of both measured and predicted CO2 values for 2023 was juxtaposed and authenticated, thus concluding the investigative cycle of this study. Key findings include: (1) The accuracy of the CLUE-S model in the study area was assessed using overall accuracy, quantity disagreement and allocation disagreement indexes. In 2022, the overall accuracy is 98.19%, the quantity disagreement is 1.7%, and the allocation disagreement is 2.2%. (2) Distinct land resource utilization characteristics in scenarios, highlighting potential impacts on economic development and pollution. (3) Increased carbon emissions across scenarios, with construction development showing the highest rise (4.170%) and agricultural development the lowest (0.766%). (4) The predictive accuracy of the validation group's CO2 concentration values can reach 99.5%. This study proposes precise CO2 prediction at the county level, thus laying the groundwork for future research endeavors. Such findings are indispensable for informing carbon policy formulation and promoting low-carbon development strategies.

Bacterial Vaginosis (BV) and Vaginal Microbiome Disorders in Women Suffering from Polycystic Ovary Syndrome (PCOS).

Introduction: Polycystic ovary syndrome (PCOS) is a multifactorial, heterogeneous endocrine and metabolic disorder in women. Due to its association with the menstrual cycle and fertility disorders, the importance of this problem is emphasized especially in patients of reproductive age. Based on a number of analyses, the effect of PCOS on altering the diversity of the microbiome (e.g., intestinal or vaginal) is suggested. Vaginal dysbiosis can result in BV (bacterial vaginosis). The purpose of this study was to assess the prevalence of BV in patients with PCOS, as well as to determine the most reliable diagnostic factors. Material and Methods: Retrospective analysis of microbiological findings (2018-2022) of PCOS patients (n = 594) of reproductive age. The present analysis focused on the results of patients with PCOS (n = 380) and vaginal discharge with pH ≥ 4.4 and suspected BV. Biological material was a vaginal swab/vaginal secretion. The most commonly used routine methods for assessing BV were the Amsel analysis and the Nugent scoring system. Results: Patients with PCOS and vaginal fluid pH ≥ 4.4 and suspected BV (n = 380) accounted for 64% of all PCOS patients (n = 594). The relationship between pH and detection of "clue cells" showed significant dependency and increased with leukocytes. The pH measurement also showed dependency on high G. vaginalis counts. In addition, the elimination of lactic acid bacteria (LAB) in vaginal secretions was associated with an increase in the number of leukocytes with increasing pH values. A marked increase in G. vaginalis was found in more than half (56.8%) of PCOS women (n = 380) with suspected BV. No dependency was observed between the absence of LAB and the diagnosis of BV on a positive G. vaginalis culture. Of the n = 380 patients with PCOS, 191 (50%) had a Nugent score ≥ 7 positive for BV. No dependency was observed between the number of patients with Candida sp. in vaginal secretions and pH, BV (with clue cells), or elevated leukocyte levels. The LRM was adjusted and the statistical model represented by the following formula was obtained: log(p/(1 - p)) = -1.18 + 1.24 × Group4.6 + 1.08 × Group4.8 + 1.66 × Group5.4. Conclusions: Based on the present analysis, BV appears to be more common in patients with PCOS than in the non-PCOS population. Chronic inflammation in PCOS patients and abnormalities in the vaginal microbiome may predispose to the development of BV. In women with PCOS, BV may be one of the unrecognized causes of infertility or complications of pregnancy. Despite the potential link between PCOS and the development of BV, the extent to which this syndrome contributes to vaginal dysbiosis and reproductive complications requires further study.

Relative Effectiveness of Morphological Analysis Training and Context Clue Training on Multidimensional Vocabulary Knowledge.

The study explored the relative effectiveness of morphological analysis training and context clue training on multidimensional EFL vocabulary knowledge. A total of 90 college English learners were equally and randomly assigned to three groups: a morphological analysis group, a context clue group, and a control group. Vocabulary development was measured in four dimensions: inferencing, grammar, meaning, and collocation. The ANOVA results indicated that both experimental groups outperformed the control group in multiple aspects of word knowledge. In addition, in the word inferencing and meaning tests, the morphological group demonstrated significantly better performance; while the context clue group showed superior word grammar and collocation knowledge. Relevant implications are discussed based on the findings.

The Pink Doughnut Sign-A Clinical Clue to Recognize Basal Cell Carcinoma Presenting as Chronic Leg Ulcer.

Chronic lower leg ulcers (LLUs) are a very common and associated with a high subjective and economic burden. They can be caused by a variety of factors. We have observed a common clinical feature in patients suffering from LLUs, which ultimately proved to be basal cell carcinomas (BCCs). We have nicknamed this sign "the pink doughnut sign." The pink doughnut sign can aid in the early recognition of such BCCs, which is crucial to prevent unnecessary suffering, treatment costs, and poor local outcomes.

Spatio-temporal evolution and trend prediction of urban ecosystem service value based on CLUE-S and GM (1,1) compound model.

Ecosystem service value (ESV) is a significant indicator related to regional ecological well-being. Evaluating ESV premised on continuous time series land benefit data can provide an accurate reference for regional ecological civilization construction and sustainable development. Taking Shijiazhuang, the capital city of Hebei Province as an example, the study analyzed land use changes based on the land use data of the continuous time series from 2000 to 2020 and introduced a socio-economic adjustment factor and biomass factor adjustment factor to construct a dynamic assessment model of ecosystem service value. The spatiotemporal changes of the ecosystem service value in Shijiazhuang City were evaluated, and the dynamic prediction of the ecosystem service value was made using the CLUE-S model and the GM (1,1) model. (1) The changes in the overall ESV and spatial pattern in Shijiazhuang are strongly linked to the change in land use, and the contribution of cultivated land, woodland, and grassland to ecosystem service value exceeds 90%. (2) Between 2000 and 2020, the value of ecosystem services illustrated a dynamic change and gradually declined, with the total amount falling from 28.003 to 19.513 billion yuan. Among individual ecosystem services, the value of regulation services suffered the most serious loss. (3) CLUE-S and GM (1,1) perform well in the prediction of ESV. The prediction outcomes illustrate that the ecosystem service value of Shijiazhuang will continue to decline by 2025, and the ecosystem value will drop to 16.771 billion yuan. This research may offer a reference for the dynamic assessment of ESV of the continuous sequence and help to promote regional ecological protection and sustainable development.

Optimal allocation for land in an arid inland basin in northwest China: framework and application based on CLUE-S and MCR models.

Reasonable planning of the limited land resources can promote the coordinated development of social economic and ecological protection. It is very important to optimize the rational distribution of land resources in the arid inland river basin because of the scarce land. In this paper, the GIS technologies of spatial analysis, conversion of land use, and its effects at small regional extent (CLUE-S) and minimum cumulative resistance (MCR) model were used to optimize the land allocation. The ecological security pattern (ESP) was constructed through using MCR model, which included ecological source and resistance surface. The dynamics of land use and spatial optimizing allocation of Shiyang River Basin in 2025 and 2030 was simulated under three different optimization scenarios including farmland protection scenario (FPS), free development scenario (FDS), and ecological security pattern scenario (ESPS). It was found that under ESPS, farmland was reduced, but woodland, grassland, and water body were increased significantly. Under FPS, land for construction was controlled effectively, a large part of homestead was converted into farmland, and the potential of unused land was developed vigorously. Furthermore, the current FDS and macro policy guidance should be comprehensively considered. The ESPS was more suitable for the scientific development of Shiyang River Basin on a long view. The combination of CLUE-S and MCR can effectively improve the optimization methods under ecological process and ecological resistance of landscape elements.

Could METS-VF provide a clue as to the formation of kidney stones?

Objective: The lifetime occurrence rate of kidney stones is 14%, making it one of the most prevalent urological conditions. Other contributing elements, such as obesity, diabetes, diet, and heredity, are also taken into account. Our research sought to explore the potential link between high visceral fat scores (METS-VF) and the occurrence of kidney stones, as a means of understanding how to prevent them. Methods: This research utilized data from the National Health and Nutrition Examination Survey (NHANES), mirroring the demographics of the United States. We carried out an in-depth analysis of the connection between METS-VF and kidney stones, based on data from 29,246 participants in the National Health and Nutrition Examination Survey spanning 2007 to 2018, involving logistic regression, segmentation, and dose-response curve analysis. Results: Our study of 29,246 potential participants found that METS-VF was positively associated with the prevalence and progression of kidney stones. After subgroup analysis by gender, race, blood pressure, and blood glucose, our results showed that the ORs for METS-VF and kidney stones were (1.49, 1.44) in males and females, respectively; while in Mexicans, whites, blacks, and In other populations, the OR values were (1.33, 1.43, 1.54, 1.86); in hypertensive and normal populations, the OR values were (1.23, 1.48); in diabetic patients and normoglycemic patients were (1.36,1.43). This proves that it works for all groups of people. Summary: Our studies demonstrate a strong connection between METS-FV and the emergence of kidney stones. It would be beneficial to investigate METS-VF as a marker for kidney stone development and progression in light of these findings.

Future land-use change predictions using Dyna-Clue to support mosquito-borne disease risk assessment.

Mosquitoes are known vectors for viral diseases in Canada, and their distribution is driven by climate and land use. Despite that, future land-use changes have not yet been used as a driver in mosquito distribution models in North America. In this paper, we developed land-use change projections designed to address mosquito-borne disease (MBD) prediction in a 38 761 km2 area of Eastern Ontario. The landscape in the study area is marked by urbanization and intensive agriculture and hosts a diverse mosquito community. The Dyna-CLUE model was used to project land-use for three time horizons (2030, 2050, and 2070) based on historical trends (from 2014 to 2020) for water, forest, agriculture, and urban land uses. Five scenarios were generated to reflect urbanization, agricultural expansion, and natural areas. An ensemble of thirty simulations per scenario was run to account for land-use conversion uncertainty. The simulation closest to the average map generated was selected to represent the scenario. A concordance matrix generated using map pair analysis showed a good agreement between the simulated 2020 maps and 2020 observed map. By 2050, the most significant changes are predicted to occur mainly in the southeastern region's rural and forested areas. By 2070, high deforestation is expected in the central west. These results will be integrated into risk models predicting mosquito distribution to study the possibility of humans' increased exposure risk to MBDs.

Integrated modeling of global change impacts on land and water resources.

There is a common scientific understanding that global change impact analysis, mitigation, and adaptation require interdisciplinary work. Integrated modeling could help to address the challenges associated with the impacts of global change. Particularly, integrated modeling that takes feedback effects into account will allow for the derivation of climate resilient land use and land management. Here, we call for more of such integrated modeling work focusing on the interdisciplinary subject of water resources and land management. As a proof-of-concept, we tightly couple a hydrologic (SWAT) and a land use model (CLUE-s) and illustrate the benefits of this coupled land and water modeling framework (LaWaCoMo) with a scenario on cropland abandonment induced by water stress. As compared to standalone model runs of SWAT and CLUE-s for the past, LaWaCoMo performs slightly better regarding measured river discharge (PBIAS: +0.8% and +1.5% compared at two gauges) and land use change (figure of merit: +6.4% and +2.3% compared to land use maps at two points in time). We show that LaWaCoMo is suitable for global change impact analysis as it is sensitive to climate and land use inputs as well as to management decisions. Our results shed light on the importance of feedback effects between land use and hydrology to assess impacts of global change on land and water resources accurately and consistently. To facilitate that the developed methodology can serve as a blueprint for integrated modeling of global change impacts, we used two freely available models that belong to the most widely used models in their respective disciplines.

Identification of new candidate drugs for primary Sjögren's syndrome using a drug repurposing transcriptomic approach.

OBJECTIVES: To date, no immunomodulatory drug has demonstrated its efficacy in primary SS (pSS). We sought to analyse potential commonalities between pSS transcriptomic signatures and signatures of various drugs or specific knock-in or knock-down genes. METHODS: Gene expression from peripheral blood samples of patients with pSS was compared with that of healthy controls in two cohorts and three public databases. In each of the five datasets, we analysed the 150 most up- and downregulated genes between pSS patients and controls with regard to the differentially expressed genes resulting from the biological action on nine cell lines of 2837 drugs, 2160 knock-in and 3799 knock-down genes in the Connectivity Map database. RESULTS: We analysed 1008 peripheral blood transcriptomes from five independent studies (868 patients with pSS and 140 healthy controls). Eleven drugs could represent potential candidate drugs, with histone deacetylases and PI3K inhibitors among the most significantly associated. Twelve knock-in genes were associated with a pSS-like profile and 23 knock-down genes were associated with a pSS-revert profile. Most of those genes (28/35, 80%) were interferon-regulated. CONCLUSION: This first drug repositioning transcriptomic approach in SS confirms the interest of targeting interferons and identifies histone deacetylases and PI3K inhibitors as potential therapeutic targets.

Evaluation and prediction of land use change impacts on ecosystem service values in Nanjing City from 1995 to 2030.

Land use changes have a considerable impact on ecosystem services (ESs). In recent years, land use changes caused by urban expansion in Nanjing City have been obvious and are expected to further change in the future. Therefore, it is urgent to quantitatively assess ecosystem service value (ESV) changes caused by previous land use changes and future potential changes in Nanjing. In this study, land use data products based on remote sensing images, Dyna-CLUE model, and the ESV equivalent coefficient method were applied to assess the impact of land use changes on ESVs in Nanjing City over the past 23 years (1995-2018), and to forecast the changes of ESV in 2030. The results indicated that the total ESVs of Nanjing City displayed a trend of first increasing and then declining in 1995-2018. From the land use classification, the water area had the largest ESV in Nanjing, followed by arable land. Additionally, the regulating service value was the highest among the four primary ESs in Nanjing from 1995 to 2030, with the highest value of 13.73 billion yuan in 2015. Among the three forecast scenarios, the ecological protection scenario had the highest total ESV and was followed by the urban expansion and business as usual scenarios. These findings may assist for the scientific decision-making of sustainable land use and ecosystem management in Nanjing City.

Development and application of cue-based feeding process in premature infants / 中国实用护理杂志

Objective:To establish a prompt based feeding process for premature infants and explore its application effects.Methods:This study was a quasi-experimental research method. Firstly, the best evidence of prompt feeding for premature infants was systematically searched and summarized, and the expert consultation method and clinical practice were used to finally formulate a prompt feeding process for premature infants. The process was applied to clinical practice. A total of 82 hospitalized premature infants in the neonatal intensive care unit of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology from October 2021 to March 2022 were selected as the control group, and routine feeding management was implemented. A total of 86 hospitalized premature infants from April to September 2022 were selected as the observation group. Feeding management for premature infants based on the prompt feeding process was followed, and the feeding efficiency, transition time of full oral feeding, and days of gastric tube retention, hospital stay and the incidence of feeding related complications in the two groups were compared.Results:The effective recovery rates of the two rounds of expert correspondence questionnaires were 100%, and the authoritative coefficients of expert opinions were 0.863 and 0.875, respectively. The Kendall harmony coefficients of expert opinions were 0.156 and 0.202, respectively, and the significance tests were all P<0.05. The total oral feeding rate of the observation group was 59.84%(5 256/8 784), the mixed feeding rate was 12.26%(1 077/8 784), and the tube feeding rate was 27.90%(2 451/8 784). Compared with the control group′s 52.20%(4 698/9 000), 14.68%(1 321/9 000), and 33.12%(2 981/9 000), the difference was statistically significant ( χ2 = 105.21, P<0.05). The transition time of full oral feeding, number of days of gastric tube retention, and hospitalization time in the observation group were (5.14 ± 1.67), (6.13 ± 1.62), and (12.77 ± 1.37) days, respectively. Compared with the control group′s (6.22 ± 1.59), (7.17 ± 1.55), and (13.72 ± 1.72) days, the differences were statistically significant ( t = 4.206, 4.26, 3.97, all P<0.05). The incidence of milk choking, hypoxia, and vomiting in the observation group were 9.30%(8/86), 6.98%(6/86), and 11.63%(10/86), respectively, which were lower than the 23.17%(19/82), 19.51%(16/82), and 34.15%(28/82) of the control group. The difference between the two groups was statistically significant ( χ2 = 5.99, 5.80, 12.16, all P<0.05). Conclusion:The application of prompt feeding process in premature infants can shorten the transition time of full oral feeding, promote the feeding process, reduce the complications caused by poor feeding, and ensure the feeding safety of premature infants.

Corrigendum: Could METS-VF provide a clue as to the formation of kidney stones?

[This corrects the article DOI: 10.3389/fendo.2023.1166922.].

The impacts of LULC and climate change scenarios on the hydrology and sediment yield of Rib watershed, Ethiopia.

Watershed-scale hydrology and soil erosion are the main environmental components that are greatly affected by environmental perturbations such as climate and land use and land cover (LULC) changes. The purpose of this study is to assess the impacts of scenario-based LULC change and climate change on hydrology and sediment at the watershed scale in Rib watershed, Ethiopia, using the empirical land-use change model, dynamic conversion of land use and its effects (Dyna-CLUE), and soil and water assessment tool (SWAT). Regional climate model (RCM) with Special Report on Emission Scenarios (SRES) and Representative Concentration Pathway (RCP) outputs were bias-corrected and future climate from 2025 to 2099 was analyzed to assess climate changes. Analysis of the LULC change indicated that there has been a high increase in cultivated land at the expense of mixed forest and shrublands and a low and gradual increase in plantation and urban lands in the historical periods (1984-2016) and in the predictions (2016-2049). In general, the predicted climate change indicated that there will be a decrease in precipitation in all of the SRES and RCP scenarios except in the Bega (dry) season and an increase in temperature in all of the scenarios. The impact analysis indicated that there might be an increase in runoff, evapotranspiration (ET), sediment yield, and a decrease in lateral flow, groundwater flow, and water yield. The changing climate and LULC result in an increase in soil erosion and changes in surface and groundwater flow, which might have an impact on reducing crop yield, the main source of livelihood in the area. Therefore, short- and long-term watershed-scale resource management activities have to be designed and implemented to minimize erosion and increase groundwater recharge.

Flood disaster mitigation modeling through participation community based on the land conversion and disaster resilience.

The objective of this research is to determine the relationship between non-structural flood disaster mitigation models to reduce the impact of floods. The analysis is carried out on the basis of community participation, land conversion, and community resilience. The 1398 household was conducted at 2019 is used as the sample of this research. This research is focused on the mitigation modeling by adopting three models (CLEAR model, CLUE-S model, DROP model) as variables, 15 indicators and 65 sub-indicators. Three hypotheses were formulated to effectively carry out the research. Structural equation model is used to investigate the close relationship between the three models. The relation between CLEAR and CLUE-S models have a positive correlation is about 14.806, CLEAR and DROP models have a close relation is about 4598, and CLUE-S and DROP models have a close positive relation is about 4.004. The results of these three models are very valuable to the central and local governments for formulating the policies programs in designing sustainable non-structural flood mitigation and subsequent policies with references to the three models above which are effective to reduce the flood events.

The Effects of the Ecological Conservation Redline in China: A Case Study in Anji County.

The Ecological Conservation Redline (ECR) of China plays an important role in avoiding ecological space occupancy and maintaining regional ecological security. Anji County in Zhejiang Province is one of the first regions to implement the ECR in China. This paper takes Anji County as an example to analyze the effects of ECR. To do this, we first set up two scenarios with the CLUE-S model: a normal land-use development scenario (NLDS) and an ECR implementation scenario (ECRS); then we compare the land use of 2010 and 2015 under NLDS and ECRS. Land use, ecosystem services value (ESV), landscape metrics, and ecological product outputs were compared between the entire county and the ECR areas. The results revealed the following: (1) From 2000 to 2015, the ecological land in Anji County decreased by 4.03%, while it decreased by 1.17% in the ECR areas. (2) In the ECR areas, there was less arable land and construction land of the ECRS than in the NLDS, which indicates the ECR impeded the expansion of construction land and arable land in the ECR areas. (3) The ECR areas account for 39% of Anji County but contribute more than 80% to the ESV of the whole county. During 2000-2015, the ESV of the entire county decreased while the ESV of the ECR areas increased. (4) From 2000 to 2015, whereas landscape fragmentation of the entire county increased, that of ECR areas decreased. (5) Since the ECR's implementation, Anji County has vigorously developed the bamboo industry, ecological agriculture, the tourism industry, and achieved rapid economic development via industrial restructuring and transformation. On the whole, the ECR has neither adversely affected land development nor economic development but instead has promoted the optimization of the land's spatial development pattern.

Clue Cells and Pseudo Clue Cells in Different Morphotypes of Bacterial Vaginosis.

Introduction: Clue cells (epithelial cells heavily covered with adherent bacteria) are an accepted clue to the diagnosis of bacterial vaginosis. However, the exact morphologic criteria of clue cells and bacterial adherence were never elaborated. Materials and Methods: We investigated adhesive and cohesive patterns of main microbiota groups in vaginal discharge using fluorescence in situ hybridization (FISH). Samples from 500 women diagnosed with bacterial vaginosis and positive for clue cells with classic microscopy were collected from 42 gynecologic practices in Berlin and reexamined in our FISH laboratory for the spatial distribution of Bifidobacteriaceae, Gardnerella, Fannyhessea vaginae (Atopobium); low G+C (guanine+cytosine) bacteria, lactobacilli, Lactobacillus iners; Lactobacillus crispatus, Gamma-Proteobacteria; and Enterobacteriaceae, Prevotella-Bacteroides, Veillonella, and Coriobacterium groups. Results: Bacterial taxa present in vaginal smears were not accidentally assembled according to their relative abundance but were built in group-specific distribution patterns, which can be well described by two features: cohesiveness to each other and adherence to epithelial cells. Accordingly, four patterns can be distinguished: dispersed (non-adherent bacteria), dispersed adherent bacteria, cohesive (non-adherent) bacteria, and cohesive adherent bacteria. Direct cohesive adherence to the epithelial cells representing true clue cells was unique for Gardnerella species and observed only in 56% of the investigated samples. In the remaining vaginal samples, the epithelial cells were mechanically entrapped in bacterial masses, and the composition was unrelated to the epithelial cell surface, building non-adherent pseudo clue cells. The proportion of women with true clue cells in their samples from different gynecologic practices varied from 19% to 80%. Discussion: Taxon indifferent imaging is inadequate for the exact analysis of the microbial layer adjacent to the vaginal epithelial cells. Morphologically seen bacterial vaginosis is a mix of at least two different conditions: biofilm vaginosis and bacterial excess vaginosis.

Evaluation of daily disposable senofilcon A contact lenses in a symptomatic population.

PURPOSE: To evaluate the comfort performance of ACUVUE OASYS® 1-Day with HydraLuxe™ Technology among symptomatic contact lens wearers by using Contact Lens User Experience (CLUE) comfort scores and Contact Lens Dry Eye Questionnaire 8 (CLDEQ-8) discomfort and dryness scores. METHODS: Three clinical trials evaluated comfort and dryness when refitting symptomatic contact lens wearers to ACUVUE OASYS® 1-Day with HydraLuxe™ lenses. This analysis combined the CLUE comfort and CLDEQ-8 scores obtained at baseline and 2-week follow-up and compared average scores between visits. Subjects were grouped by habitual lens modality (daily disposable or daily wear reusable) and habitual lens material (silicone hydrogel or hydrogel). The analysis included data from 107 subjects. RESULTS: Significant increases in mean CLUE comfort scores between baseline and 2-week follow-up occurred in all subject groups across habitual lens modality and material, indicating an improvement in overall comfort. CLUE comfort score improved clinically (≥5-point increase) among 75.7% of subjects (81/107). Similarly, significant decrease in mean CLDEQ-8 scores between baseline and 2-week follow-up occurred in all subject groups, indicating a decrease in the prevalence of dryness and discomfort symptoms. CLDEQ-8 score improved clinically (≥3-point reduction) among 82.2% of subjects (88/107). A majority of subjects (57.0%) became asymptomatic (CLDEQ-8 score ≤ 11 points) after 2 weeks of bilateral wear. CONCLUSION: Refitting symptomatic contact lens patients to ACUVUE OASYS® 1-Day with HydraLuxe™ can improve overall comfort and reduce symptoms of dryness and discomfort, irrespective of the previous lens modality or habitual lens material.