Does enterprise digital transformation contribute to green innovation? Micro-level evidence from China.

The synergy of digitalization and greening has emerged as a prominent means to achieve the goal of "carbon peaking and carbon neutrality". Given its significant contribution to carbon emissions, the impact of digital transformation on green innovation in manufacturing enterprises remains a longstanding research hotspot. Therefore, based on the data from China A-share listed manufacturing companies spanning from 2007 to 2022, this paper empirically analyzes the influence and mechanism of digital transformation on green innovation. Our findings reveal that digital transformation can significantly promote green innovation in manufacturing enterprises, with a particularly pronounced effect on substantive green innovation. These conclusions withstand rigorous robustness tests. Mechanism analysis shows that digital transformation can facilitate green innovation by improving internal control quality and fostering industry-university-research cooperation. Moreover, our moderation analysis reveals that both equity incentives and compensation incentives strengthen the positive relationship between digital transformation and green innovation in manufacturing enterprises. Heterogeneity analysis proves that digital transformation exerts a more pronounced impact on green innovation of state-owned manufacturing enterprises, non-heavily polluted manufacturing enterprises, and enterprises located in regions with strong intellectual property protection. Furthermore, the transformation of digital underlying technologies is more conducive to fostering green innovation compared to practical application transformation. Subsequent investigation into the economic and social effects of green innovation indicates that it effectively reduces pollution emissions from manufacturing enterprises without compromising their development. Additionally, the emission reduction and income-generating effect resulting from digital transformation primarily manifest through substantive green innovation. This research expands upon the theory regarding the impact of digital transformation on green innovation in micro-manufacturing enterprises, providing empirical support for facilitating low-carbon transformations among manufacturing enterprises under the goal of "carbon peaking and carbon neutrality".

Delineation of target volume by radiation therapists during online adaptive radiation therapy: What authorization?

The evolution of radiation therapy techniques goes hand in hand with the evolution of the profession of radiation therapist. In the particular context of online adaptive radiotherapy based on cone beam computed tomography images, delegation of certain tasks from the physician to the radiation therapist is possible within the framework of a cooperation protocol. This delegation requires prior theoretical and practical training. It enriches the practice of radiation therapists by allowing them to acquire new skills and greater autonomy. It foreshadows access for radiation therapists to advanced practice.

Shifts in Residential Mobility Predict Shifts in Culture.

Does residential mobility change cultures, or is it merely a downstream indicator for other forces? Using large-scale surveys of citizens of 18 industrialized nations, we find that increased rates of residential mobility predict living in a more dynamic society at least 10 years in the future: one in which residents are more satisfied with their lives, have greater optimism, endorse more individualistic concepts, are more open to new ideas, have a greater sense of freedom of action, feel able to make friends more easily, express a more cosmopolitan identity, believe that their society rewards merit, and hold their community to a higher standard for treatment of minorities. These findings are echoed in the experience of Americans who have themselves recently moved, where we find that having successfully moved predicts a future sense of personal thriving, optimism, and a belief that merit is rewarded.

Evolutionary game analysis of multi-agent cooperation strategy analysis in agricultural water conservancy PPP project under digitization background.

This study constructed a system dynamics (SD) evolutionary game model, from which we analyzed the conditions that need to be met by multi-agents to achieve cooperation in agricultural water conservancy (AWC) Public-Private Partnership (PPP) projects. Simultaneously, this study used numerical simulation to depict the impact of initial participation willingness, reward, punishment, income, and other parameters of local governments, project enterprises, and farmers on the evolution strategy. The results firstly showed that the basic conditions for tripartite cooperation are to strengthen the rewards and punishments for project enterprises and improve the participation benefits of farmers. Secondly, it showed that increasing the rewards for farmers and improving the project dividend benefits can effectively motivate farmers to participate. Thirdly, it showed that enhancing the incentive subsidies and reputation benefits for project enterprise's participation, as well as strengthening the supervision of local government, boosts the motivation of project enterprises significantly. However, it is vital to ensure that the reward amounts are not too high to allow local government to play its guiding role efficiently. Lastly, the results indicated that digital technology can help reduce the participation cost of local government, project enterprises and farmers, and improve the external reputation benefits of each participant, thus forming a win-win situation for all three participants. Analyzing the cooperation strategies of the three parties in AWC PPP projects provides theoretical support and a decision-making basis for the efficient operation of AWC PPP projects under the digital background, and also provides practical policy recommendations for the high-quality development of AWC.

Increasing benefits in one-time public goods does not promote cooperation.

The long tradition of research on cooperation includes a well-established finding that individuals respond to the degree of conflict between self- and collective interests (that is, the relative benefits from cooperation) in providing public goods. Existing empirical evidence builds upon settings where participants make multiple decisions or strategically consider alternative scenarios. Here, we consider a decision setting where participants face a one-time (single-decision) setting. One-time cooperative encounters often occur in volunteering or donating to immediate needs for crisis relief. For these distinct and highly relevant settings, we report a lack of responsiveness to increases in cooperation benefits, thereby highlighting limits to our understanding of the determinants of one-time cooperation encounters. Across two studies, n = 2,232 individuals participate in treatments where we vary across participants the relative benefit from contributing to a public good (that is, the marginal per capita return, the MPCR). We examine decisions from alternative participant pools (UK general population vs. students), implementations varying the physical distance between participants (online vs. in the laboratory), and more complex decision settings considering group-to-group interactions including not only providers but also donors to public goods. Throughout, neither average contribution levels, nor the distribution of contributions are significantly affected by the increases in cooperation benefits. The mechanism behind these results can be explained by the close correlation between expectations of other's cooperation and own cooperation, and the fact that these expectations do not increase with higher benefits from cooperation.

Intraspecific cooperation allows the survival of Staphylococcus aureus staff: a novel strategy for disease relapse.

BACKGROUND: The contribution of interspecies interactions between coinfecting pathogens to chronic refractory infection by affecting pathogenicity is well established. However, little is known about the impact of intraspecific interactions on infection relapse, despite the cross-talk of different strains within one species is more common in clinical infection. We reported a case of chronic refractory pulmonary infection relapse, caused by two methicillin-sensitive S. aureus (MSSA) strains (SA01 and SA02) and revealed a novel strategy for relapse via intraspecific cooperation. METHODS: The hemolytic ability, growth curve, biofilm formation, virulence genes and response of G. mellonella larvae to S. aureus infection were analysed to confirm this hypothesis. RESULTS: SA02 hemolytic activity was inhibited by SA01, along with the expression of hemolysin genes and the virulence factor Hla. Additionally, SA01 significantly enhanced the biofilm formation of SA02. AIP-RNAIII may be a possible pathway for this interaction. Compared with mono-infection, a worse outcome (decreased larval survival and increased microbial burden) of the two MSSA strains coinfected with G. mellonella confirmed that intraspecific interactions indeed enhanced bacterial survival in vivo. CONCLUSION: The intraspecific interaction of S. aureus could lead to chronic refractory infection via pathogenicity changes.

Punishment is slower than cooperation or defection in online network games.

Punishment serves as a balancing force that dissuades people from acting selfishly, which complements cooperation as an essential characteristic for the prosperity of human societies. Past studies using economic games with two options (cooperation and defection) reported that cooperation decisions are generally faster than defection decisions and that time pressure possibly induces human players to be more intuitive and thus cooperative. However, it is unclear where punishment decisions sit on this time spectrum. Therefore, we recruited human players and implemented two series of online network games with cooperation, defection, and punishment options. First, we find that punishment decisions are slower than cooperation or defection decisions across both game series. Second, we find that imposing experimental time pressure on in-game decisions neither reduces nor increases the frequency of punishment decisions, suggesting that time pressure may not directly interact with the mechanisms that drive players to choose to punish.

Auditing road safety achievement using MEREC-ARAS-QBKM model: an empirical study for APEC member economies.

Progress monitoring and action recalibrations are advocated as promising methods for improving road safety, which significantly relates to economic stability and social development. To achieve this, an auditing framework that can evaluate road safety and aid in policymaking is urgently required. To this end, this study developed a systemic decision model that integrates the method based on the removal effects of criteria (MEREC), additive ratio assessment (ARAS), and quantile-based k-means clustering (QBKM), termed MEREC-ARAS-QBKM, with the aim of auditing road safety achievements and providing corresponding policy suggestions with substantial reliability. In particular, the performance of the traditional k-means clustering model was improved by implanting quantiles to determine the initial clustering, which overcomes the uncertainty of k-means clustering owing to the variety of initial cluster centers. Multiple comparisons of empirical results based on a case study of the Asia-Pacific Economic Cooperation (APEC) member economies verified the robustness of the proposed model, demonstrating its applicability, practicability, and reliability in handling real-world multi-criteria decision-making problems in the field of road safety. The empirical findings show that road safety developments among the APEC countries are of class differentiation, suggesting an urgent regional benchmarking. Overall, the proposed methodology empowers decision-makers and policymakers in APEC to swiftly formulate effective action plans, countermeasures, and investment schemes, ultimately contributing to the enhancement of road safety performance and socio-economic benefit across APEC members.

Cooperation objective evaluation in aviation: validation and comparison of two novel approaches in simulated environment.

Introduction: In operational environments, human interaction and cooperation between individuals are critical to efficiency and safety. These states are influenced by individuals' cognitive and emotional states. Human factor research aims to objectively quantify these states to prevent human error and maintain constant performances, particularly in high-risk settings such as aviation, where human error and performance account for a significant portion of accidents. Methods: Thus, this study aimed to evaluate and validate two novel methods for assessing the degree of cooperation among professional pilots engaged in real-flight simulation tasks. In addition, the study aimed to assess the ability of the proposed metrics to differentiate between the expertise levels of operating crews based on their levels of cooperation. Eight crews were involved in the experiments, consisting of four crews of Unexperienced pilots and four crews of Experienced pilots. An expert trainer, simulating air traffic management communication on one side and acting as a subject matter expert on the other, provided external evaluations of the pilots' mental states during the simulation. The two novel approaches introduced in this study were formulated based on circular correlation and mutual information techniques. Results and discussion: The findings demonstrated the possibility of quantifying cooperation levels among pilots during realistic flight simulations. In addition, cooperation time is found to be significantly higher (p < 0.05) among Experienced pilots compared to Unexperienced ones. Furthermore, these preliminary results exhibited significant correlations (p < 0.05) with subjective and behavioral measures collected every 30 s during the task, confirming their reliability.

A simple model and rules for the evolution of microbial mutualistic symbiosis with positive fitness feedbacks.

The evolution of microbe-microbe mutualistic symbiosis is considered to be promoted by repeated exchanges of fitness benefits, which can generate positive fitness feedbacks ('partner fidelity feedback') between species. However, previous evolutionary models for mutualism have not captured feedback dynamics or coupling of fitness between species. Here, a simple population model is developed to understand the evolution of mutualistic symbiosis in which two microbial species (host and symbiont) continuously grow and exchange fitness benefits to generate feedback dynamics but do not strictly control each other. The assumption that individual microbes provide constant amounts of resources, which are equally divided among interacting partner individual, enables us to reveal a simple rule for the evolution of costly mutualism with positive fitness feedbacks: the product of the benefit-to-cost ratios for each species exceeds one. When this condition holds, high cooperative investment levels are favored in both species regardless of the amount invested by each partner. The model is then extended to examine how symbiont mutation, immigration, or switching affects the spread of selfish or cooperative symbionts, which decrease and increase their investment levels, respectively. In particular, when a host associates with numerous symbionts without enforcement, neither mutation nor immigration but rather random switching would allow the spread of cooperative symbionts. Examples using symbiont switching for evolution would include large ciliates hosting numerous intracellular endosymbionts. The simple model and rules would provide a basis for understanding the evolution of microbe-microbe mutualistic symbiosis with positive fitness feedbacks and without enforcement mechanisms.

Non-kin interactions between Bacillus subtilis soil isolates limit the spread of swarming deficient cheats.

Cooperative behaviors in human, animal, and even microbial societies are vulnerable to exploitation. Kin discrimination has been hypothesized to help stabilize cooperation. However, the mechanisms that sustain cooperative behavior remain poorly understood. Here, we investigate the role of kin discrimination in limiting the spread of cheats in adjoining populations during surfactant dependent cooperative swarming over surfaces using the bacterium Bacillus subtilis as a model organism. We show that mixing surfactant secreting cooperators and cheats that do not produce surfactants at 1:1 initial ratio quickly leads to cooperation collapse. However, when such common swarms encounter non-kin B. subtilis swarms, the proportion of the surfactant non-producers decreases, suggesting that kinship dependent interactions may limit cheats' advantage in an adjoining population. To further validate this finding, we subjected wild-type cooperators to multiple transient encounters with kin and non-kin swarms over 20 cycles of experimental evolution. The evolved populations exposed to non-kin swarms less frequently contained defective swarming phenotypes compared to those encountering kin swarms. Altogether, our results support the prediction that the spread of cheats in an adjoining bacterial population is impeded by kin discrimination interactions which might have a role in stabilizing cooperative behavior in evolving populations.

Pharmaceutical Inspection Co-operation Scheme: An Overview.

To address the challenges posed by the globalization of regulatory agencies, it is essential to harmonize regulatory requirements, assess Good Manufacturing Practice (GMP) compliance, license production facilities, manage product recalls, and improve information exchange. The Pharmaceutical Inspection Co-operation Scheme (PIC/S) provides a robust framework for tackling these global issues. Through the PIC/S GMP Forum, PIC/S facilitates informal interactions among non-member authorities, professionals, and various organizations with the Committee, fostering networking and collaboration. Furthermore, PIC/S has developed a comprehensive guide on GMP requirements for inspectorates and organizations, ensuring consistent standards across borders. The scheme collaborates with other organizations to enhance and complement collective efforts. With 56 countries involved in PIC/S, whether as members or through the Accession and Pre-Accession Process, the exchange of inspection reports among authorities verifies compliance with PIC/S standards, leading to fewer and more targeted inspections and reducing redundancy. This study's purpose is to establish uniform GMP standards by providing extensive training for inspectors and promoting collaboration and networking among regional and international bodies, regulatory authorities, and other relevant organizations. This approach seeks to build trust in inspections, optimize resource use, and foster a more efficient regulatory environment. Through these efforts, PIC/S continues to play a pivotal role in advancing global pharmaceutical regulatory practices.

The European Universities initiative: between status hierarchies and inclusion.

Using a dataset of higher education institutional alliances within the framework of the European University initiative (EUi), we test empirically whether the policy-defined goal of a relative balance between excellence and inclusiveness within the scheme has been achieved. Specifically, we provide a descriptive and analytical account of the diversity of the higher education institutions (HEIs) participating in the EUi, the composition of-as well as the mechanisms behind-the formation of individual alliances. We observe that alliance formation activated the deep sociological mechanisms of hierarchisation, with the alliances largely reproducing the existing hierarchy of European HEIs. Specifically, we argue that the global-level stratification hierarchy cast by rankings influences the participation of individual institutions and-although to a more limited extent-the formation/structure of the alliances. Further, we demonstrate that the EUi has strengthened existing ties since most alliances thus far have built on existing forms of collaboration. However, we also show empirically that some of the distinctive policy design measures, namely the requirement for broad geographical coverage and generically framed rules for participation, as well as opening the initiative to new alliances and encouraging enlargement of the existing ones, have generated opportunities for involvement of the lower-status institutions. This broadened the scope of the EUi beyond the core of top-ranked research universities located in the knowledge production centres of Europe. We suggest that these observations may have important implications for how the intended extension of the EUi may be implemented in the future. Supplementary Information: The online version contains supplementary material available at 10.1007/s10734-023-01167-w.

[Protocol for osteoporosis screening in CPTS]. / Protocole de dépistage de l'ostéoporose en CPTS.

Osteoporosis is a chronic disease that affects bone density and quality, making the skeleton more fragile and susceptible to fracture in the event of minor trauma, or even spontaneously in the most severe cases. It seriously affects patients' quality of life and generates considerable costs for healthcare systems. Given this situation, early detection and management of this disease is crucial. With this in mind, the Communauté Professionnelle Territoriale de Santé (CPTS) in southern Toulouse has developed a care pathway based on a cooperation protocol designed to facilitate screening for the disease.

Oxytocin and shared intentionality are positively associated with cooperation in children.

While humans cooperate with unrelated individuals to an extent that far outstrips any other species, we also display extreme variation in decisions about whether to cooperate or not. A diversity of cognitive, affective, social, and physiological mechanisms interact to shape these decisions. For example, group membership, shared intentionality talk (i.e. talk about shared goals), and natural initial oxytocin levels are linked to cooperation in adults in an optimal foraging paradigm that is loosely modelled on the iterated prisoner's dilemma. In this 'egg hunt', shared intentionality talk was key to achieving cooperation, and it drove cooperation more between participants who shared the same group membership (and who also had higher initial oxytocin levels). Such complex interactions raise the question of the age at which humans develop the necessary mechanisms to cooperate effectively in the egg hunt game. Here, we tested children in secondary school aged between 10 and 14 years. We found that, as for adults, shared intentionality talk was crucial for successful cooperation. Furthermore, initial oxytocin levels correlated with cooperation through shared intentionality talk. In contrast, group membership did not affect behaviour. Finally, pre- and post-experiment oxytocin levels showed various interactions with group membership and sex. Thus, children's performance was relatively similar to adults while showing some differences with respect to underlying mechanisms. Our study is a rare contribution to further our understanding of the role of oxytocin in early adolescent social behaviour.

Aus Klinik und Praxis / From Clinic and Practice. Autismus in der systemischen Gruppenpsychotherapie: "Gemeinsam Stark" ein Versorgungsmodell für Kinder- und Jugendliche aus der Praxis / Autism in Systemic Group Psychotherapy: "Strong Together" a Care Model for Children and Adolescents from Practice.

Autism in Systemic Group Psychotherapy: "Strong Together" a Care Model for Children and Adolescents from Practice Awareness of people with autism in our society is constantly increasing. Nevertheless, ambiguities and caution in dealing with autistic clients are still tangible. Due to the growing demand, there is a shortage of care for clients on the autism spectrum. This applies in particular to group therapy services in German-speaking countries. However, the international AWMF guidelines state that group therapy is the therapy method of choice for children and adolescents with autistic perception. In order to counteract this gap in care, this article presents a systemic group therapy for autistic people. It explains the extent to which the systemic approach in combination with a multimodal approach is a beneficial approach. It also highlights the importance of expanding the range of care services, interdisciplinary cooperation, and exchange. The compatibility of practice and research in systemic psychotherapy will be explained, teamwork in private practice will be emphasized, therapeutic experiences will be shared and an outlook on ongoing evaluation research will be presented.

Salmonella in the food chain within the Gulf Cooperation Council countries.

Infections caused by bacteria originating from tainted food sources are a widespread concern due to their large economic impact and detrimental effects on public health. We aimed to explore literature focusing on the presence of Salmonella in the food supply chains of Gulf Cooperation Council (GCC) countries and to provide an overview of available information concerning health-related issues and the status of salmonellosis in humans in GCC countries. The reviewed evidence underscored a gap in our comprehensive understanding of the prevalence of Salmonella in the food supply of GCC countries. Molecular characterization efforts to pinpoint the sources of Salmonella in these nations were limited. Surveys targeting Salmonella in the food supply of GCC countries have been infrequent. While qualitative data indicated the presence or absence of Salmonella, there was a noticeable lack of quantitative data detailing the actual quantities of these bacteria in chicken meat supplies across GCC countries. Although reports regarding Salmonella in animal-derived foods were common, the literature highlighted in this review emphasized the persistent challenge that Salmonella pose to food safety and public health in GCC countries. Addressing this issue requires concerted efforts to enhance surveillance, improve control measures, and promote greater awareness among stakeholders in the food supply chain.

Variables associated with the relationship between obesity and mental health among university students in the Gulf Cooperation Council countries: a systematic review.

Background: Various factors, including dietary habits, lifestyle choices, socio-economic status, cultural attitudes, academic stress, and access to mental health support services, influence the relationship between obesity and mental health among university students in Gulf Cooperation Council (GCC) countries. Understanding these complex interactions is crucial for developing effective interventions to promote both physical and mental well-being among students in the region. Therefore, this systematic review aims at understanding the variables associated with the relationship between obesity and mental health among university students in the (GCC) countries. Methods: This systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) [CRD42024517806]. We conducted a systematic literature search using electronic databases including PubMed, PsycINFO, Scopus, CINAHL, Web of Science, and Google Scholar to identify relevant studies published up to 28-February-2024. A narrative synthesis approach was employed to summarize the findings of included studies. Data were synthesized according to predefined themes related to variables associated with the relationship between obesity and mental health among university students in GCC countries. Results: The prevalence of overweight and obesity among university students in GCC countries is alarmingly high, with a mean rate of 29.4%. Depression, anxiety, and body image dissatisfaction are significantly associated with obesity in this population. Poor sleep patterns are both a predictor and a consequence of obesity-related mental health issues. Socio-cultural factors play a crucial role in shaping students' perceptions of body image and mental health. Conclusion: These findings highlight the importance of comprehensive approaches to address the intertwined nature of obesity and mental health in this population, necessitating targeted interventions and further research efforts.

Give some, keep some, put some: The language of sharing in children.

Sensitivity to linguistic cues, in theory, can change the interpretation of social and game theoretical behavior. We tested this in a pair of experiments with children aged 4 and 5 years. Children were asked to give some, keep some, or put some stickers for themselves or for another player (a puppet) after collaborative activities. We found that the direction of the verb did influence how selfish the younger children were. We also had children tidy up the toys after each activity to determine their interpretation of some. Children could derive the pragmatic scalar implicature linked to some (i.e., interpreting it as meaning not all), and they did so particularly when it affected them personally. These findings have important implications for the stability of other-regarding preferences and the importance of instructions in games.