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Korean Journal of Medicine ; : 545-549, 2016.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-77224

ABSTRACT

Amyloidosis is characterized by the extracellular deposition of amyloid in various tissues and organs, particularly the kidney and heart. The estimated incidence of systemic amyloidosis is at least 8 per million population per year. However, few cases of systemic amyloidosis in renal allografts have been reported. A stable renal transplant recipient was admitted with proteinuria and dyspnea on exertion. The M-peak was found on serum and urine protein electrophoresis, and lambda (λ) dominance was confirmed by serum and urine free-light-chain test. The patient was diagnosed with systemic amyloidosis of a renal allograft, by allograft biopsy, at 22 years after renal transplantation. We report a case of AL amyloidosis in a stable renal allograft and review the medical literature.


Subject(s)
Humans , Allografts , Amyloid , Amyloidosis , Biopsy , Dyspnea , Electrophoresis , Heart , Immunoglobulin Light Chains , Incidence , Kidney , Kidney Transplantation , Proteinuria , Transplant Recipients
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