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1.
Article in English | MEDLINE | ID: mdl-39229717

ABSTRACT

At present, the power conversion efficiency (PCE) of perovskite solar cells (PSCs) has reached 26.1%. Polycrystalline perovskite films prepared by sequential deposition are often accompanied by excess PbI2. Although excess PbI2 can reduce the internal defects of the perovskites and promote charge transfer, excess PbI2 is unevenly distributed in the perovskites and easily decomposed into the composite center of charge. Therefore, the growth and distribution of PbI2 crystals can be regulated by introducing 4-fluoroaniline (4-FLA) as an additive into the precursor of PbI2. We observe that the presence of an amino group in 4-FLA leads to a reduction in the strength of van der Waals forces between PbI2 layer structures, thereby facilitating the uniform dispersion of excess PbI2 within the perovskites. Additionally, 4-FLA is restricted from being embedded in the PbI2 layer due to the steric hindrance of 4-FLA and the hydrogen bond interaction between nitrogen atoms and PbI2. Therefore, it leads to better dispersion of PbI2, resulting in better passivation and device efficiency. Based on the hydrophobicity of the benzene ring, the modified perovskite film shows excellent hydrophobicity. Ultimately, we achieved 21.63% PCE and 1.16V VOC. This provides an effective strategy for regulating excess PbI2 to achieve efficient and stable PSCs.

2.
Heliyon ; 10(16): e35957, 2024 Aug 30.
Article in English | MEDLINE | ID: mdl-39220904

ABSTRACT

Defect detection is critical to industrial quality control in leather production engineering. The various sizes and locations of defects in leather, as well as significant differences within the same class and indistinctive variations between different classes of defects, contribute to the complexity of the problem. To address this challenge, we propose a Multi-Layer Residual Convolutional Attention (MLRCA) approach. MLRCA enhances its ability to capture both intra-class and inter-class differences by enhancing the semantic feature representation in the backbone network. To improve multiscale fusion effects, we also incorporate the MLRCA module into the feature pyramid network (FPN) and propose a new multi-layer residual convolution attention feature pyramid network (ML-FPN). This approach enables more accurate identification of leather defects at a more detailed level by selectively capturing contextual information from different domains. We then implement the Side-Aware Boundary Localization (SABL) detection head, which accurately locates defects and helps the network distinguish between similar defect categories for more precise positioning. To validate the effectiveness of our approach, we conducted ablation experiments on the created leather dataset. Comparative experiments demonstrate the excellent capability of our model to detect minor defects. The model achieved 83.4, 89.7, and 85.6 for the AP, AP50, and AP75 evaluation metrics. In addition, the model achieves 71.3, 89.9, and 88.9 for APS, APM, and APL. Our approach has been confirmed feasible through experimentation and provides new insights for automated leather defect detection methods.

4.
Cureus ; 16(8): e65940, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39221317

ABSTRACT

Myelomeningocele (MMC) is an in-utero closure defect of the posterior portion of the neural tube, and it is the most common neural tube defect (NTD) compatible with life. It is usually associated with other congenital malformations, such as hydrocephalus and Chiari type 2 syndrome. Therefore, the long-term outcome depends on early repair, and the surgery is urgently scheduled. Newborns with MMC are a special population that requires meticulous preoperative preparation to maintain hemodynamic stability during the procedure and a favorable outcome. In this case report, we describe the challenges of unruptured myelomeningocele closure surgery in a newborn with 12 hours of life. This special case emphasizes the importance of a multidisciplinary approach between anesthesiologists, neurosurgeons, and plastic surgeons to provide the best care to this subset of patients.

5.
Cureus ; 16(8): e68304, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39221329

ABSTRACT

Managing large nasal defects following Mohs surgery presents complex reconstructive challenges due to the nose's prominent and visible nature. These cases require a careful balance of preserving structural integrity, optimizing cosmetic outcomes, and maintaining vascular health. In situations where primary closure is impractical due to defect size and location, innovative techniques like the double rhomboid transposition flap offer versatile solutions, addressing both aesthetic concerns and functional requirements. The double rhomboid flap allows surgeons to achieve continuity of surrounding tissue, ensuring aesthetically pleasing texture, color, and thickness while minimizing complications like skin tension and potential airway issues. This case highlights the reconstructive challenges faced in managing large nasal defects following Mohs micrographic surgery for basal cell carcinoma. An 84-year-old male presented with a significant nasal defect following Mohs surgery that involved the dorsum, sidewall, tip, and ala, complicating primary closure due to skin tension and cosmetic concerns. Utilizing a double rhomboid transposition flap technique allowed for effective aesthetic and structural reconstruction, addressing skin tension and preserving nasal symmetry. This case emphasizes the importance of tailored reconstructive strategies to achieve optimal cosmetic and functional outcomes in complex nasal Mohs defects.

6.
Pediatr Surg Int ; 40(1): 246, 2024 Aug 30.
Article in English | MEDLINE | ID: mdl-39222260

ABSTRACT

BACKGROUND: The authors sought better outcomes for uncomplicated gastroschisis through development of clinical practice guidelines. METHODS: The authors and the American Pediatric Surgical Association Outcomes and Evidenced-based Practice Committee used an iterative process and chose two questions to develop clinical practice guidelines regarding (1) standardized nutrition protocols and (2) postnatal management strategies. An English language search of PubMed, MEDLINE, OVID, SCOPUS, and the Cochrane Library Database identified literature published between January 1, 1970, and December 31, 2019, with snowballing to 2022. The Appraisal of Guideline, Research and Evaluation reporting checklist was followed. RESULTS: Thirty-three studies were included with a Level of Evidence that ranged from 2 to 5 and recommendation Grades B-D. Nine evaluated standardized nutrition protocols and 24 examined postnatal management strategies. The adherence to gastroschisis-specific nutrition protocols promotes intestinal feeding and reduces TPN administration. The implementation of a standardized postnatal clinical management protocol is often significantly associated with shorter hospital stays, less mechanical ventilation use, and fewer infections. CONCLUSIONS: There is a lack of comparative studies to guide practice changes that improve uncomplicated gastroschisis outcomes. The implementation of gastroschisis-specific feeding and clinical care protocols is recommended. Feeding protocols often significantly reduce TPN administration, although the length of hospital stay may not consistently decrease.


Subject(s)
Gastroschisis , Gastroschisis/surgery , Humans , United States , Infant, Newborn , Practice Guidelines as Topic , Societies, Medical , Pediatrics/standards , Pediatrics/methods
7.
World Neurosurg ; 2024 Aug 31.
Article in English | MEDLINE | ID: mdl-39222840

ABSTRACT

OBJECTIVE: Supportive radiologic signs may be needed to diagnose spondylolysis via lumbar magnetic resonance imaging (MRI). In spondylolysis (SL), the slight displacement of the corpus forward and lamina posteriorly can cause the interposition of posterior epidural fat (EFI), which is normally segmental. This study aimed to determine the diagnostic value of EFI, an indirect sign of SL, on lumbar mid-sagittal T1-weighted MRI. METHODS: The lumbar MRI of 115 randomly selected patients with SL and degenerative disc disease (DDD) was randomized and assessed for the presence or absence of EFI by two masked observers. These observers were not permitted to examine the pars region. Inter-observer agreement was tested using Cohen's kappa coefficient. RESULTS: EFI was positive in 98 (85%) of 115 patients with SL, 14 (12%) in the DDD group, and 6 (5%) with an upper vertebral level adjacent to the SL. The difference was statistically significant (P < 0.01). In patients with SL, the EFI positivity rate was highest at L5 (94%) and lowest at L3 (33%). EFI positivity was observed in 13% of the patients with DDD. The specificity, sensitivity, positive predictive value, negative predictive value, and accuracy of EFI in diagnosing SL were mean 79%, 89%, 96%, 86%, and 96%, respectively. The highest diagnostic value of EFI was at the L5 level, where intra- and inter-observer reliability were nearly perfect. CONCLUSION: Epidural fat interposition is an indirect radiological finding with high reliability in diagnosing spondylolysis with mid-sagittal T1-weighted images in lumbar MRI.

8.
J Orthop Res ; 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39219262

ABSTRACT

Benign, locally aggressive tumors of the distal femur are typically treated with intralesional curettage and polymethylmethacrylate (PMMA) cementation. However, it is not known whether plate fixation should be added to biomechanically augment these PMMA-filled defects. The purpose of this study was to evaluate the performance of two competing techniques for reconstruction of a distal femoral defect. For this biomechanical study, we used 12 composite femurs with properties comparable to bone. In nine femurs, identical contained medial distal femoral defects were created using a robotic arm. Group A contained three intact femurs, Group B three femurs with an unfilled defect, Group C three femurs reconstructed with PMMA alone, and Group D three femurs reconstructed with PMMA plus a medial locking plate. Locations of greatest stress concentration were determined by PhotoStress analysis, then three strain gauges were applied to each specimen at these high-stress locations. Specimens were loaded within a physiologic range followed by loading to failure. Outcome measures included construct stiffness, strain along the distal femur, and load at failure. Results showed that stiffness and strain were not significantly different between reconstructive techniques; however, both techniques reduced tensile strain along the popliteal surface by approximately 40% compared to non-reconstructed specimens. All specimens failed at the femoral neck before failing at the distal femur. These findings suggest that plate augmentation of PMMA-filled distal femoral defects like the one in this study offers insignificant biomechanical benefit within physiologic loads and therefore may be unnecessary.

9.
Small ; : e2406179, 2024 Sep 02.
Article in English | MEDLINE | ID: mdl-39221682

ABSTRACT

For BixSb2- xTe3 (BST) in thermoelectric field, the element ratio is easily influenced by the chemical environment, deviating from the stoichiometric ratio and giving rise to various intrinsic defects. In P-type polycrystalline BST, SbTe and BiTe are the primary forms of defects. Defect engineering is a crucial strategy for optimizing the electrical transport performance of Bi2Te3-based materials, but achieving synchronous improvement of thermal performance is challenging. In this study, mesoporous SiO2 is utilized to successfully mitigate the adverse impacts of vacancy defects, resulting in an enhancement of the electrical transport performance and a pronounced reduction in thermal conductivity. Crystal and the microstructure of the continuous modulation contribute to the effective phonon-electronic decoupling. Ultimately, the peak zT of Bi0.4Sb1.6Te3/0.8 wt% SiO2 (with a pore size of 4 nm) nanocomposites reaches as high as 1.5 at 348 K, and a thermoelectric conversion efficiency of 6.6% is achieved at ΔT = 222.7 K. These results present exciting possibilities for the realization of defect regulation in porous materials and hold reference significance for other material systems.

10.
Angew Chem Int Ed Engl ; : e202413108, 2024 Sep 11.
Article in English | MEDLINE | ID: mdl-39262088

ABSTRACT

Antimony selenosulfide (Sb2(S,Se)3) has obtained widespread concern for photovoltaic applications as a light absorber due to superior photoelectric features. Accordingly, various deposition technologies have been developed in recent years, especially hydrothermal deposition method, which has achieved a great success. However, device performances are limited with severe carrier recombination, relating to the quality of absorber and interfaces. Herein, bulk and interface defects are simultaneously suppressed by regulating heterogeneous nucleation kinetics with barium dibromide (BaBr2) introduction. In details, the Br adsorbs and dopes on the polar planes of cadmium sulfide (CdS) buffer layer, promoting the exposure of nonpolar planes of CdS, which facilitates the favorable growth of [hk1]-Sb2(S,Se)3 films possessing superior crystallinity and small interface defects. Additionally, the Se/S ratio is increased due to the replacement of S/Se by Br, causing a downshift of the Fermi levels with a benign band alignment and a shallow-level defect. Moreover, Ba2+ is located at grain boundaries by coordination with S and Se ions, passivating grain boundary defects. Consequently, the efficiency is increased from 7.70% to 10.12%. This work opens an avenue towards regulating the heterogeneous nucleation kinetics of Sb2(S,Se)3 film deposited via hydrothermal deposition approach to optimize its crystalline orientation and defect features.

11.
Article in English | MEDLINE | ID: mdl-39262208

ABSTRACT

Perovskite multiple quantum wells (MQWs) have shown great potential in the field of light-emitting diodes (LEDs). However, the random formation of QWs with varying well widths (n numbers) often leads to suboptimal interface defects and charge transport issues. Here, we reveal that the crystallization sequence of bromide-based perovskite MQWs is large-n QWs preceding small-n QWs. With this insight, we prevent the crystallization of subsequent small-n QWs by reducing the crystallization rate, ultimately resulting in the crystallization of only n = 5 QWs. This reduction in the crystallization rate is achieved through the chemical interaction of dual additives with perovskite constituents. Additionally, the chemical interaction effectively passivates the uncoordinated lead ions defects. Consequently, pure-phase perovskite QWs with a high photoluminescence quantum efficiency of 75% are achieved. The resulting green LEDs achieve a peak external quantum efficiency of 17.1% and a maximum luminance of 29,480 cd m-2, which is attractive for full-color display applications of perovskites.

12.
J Stomatol Oral Maxillofac Surg ; : 102066, 2024 Sep 06.
Article in English | MEDLINE | ID: mdl-39245287

ABSTRACT

OBJECTIVE: To investigate the effect of different forms of autolyzed antigen-extracted allogeneic(AAA) bone combined with vascular endothelial growth factor (VEGF) on bone reconstruction. METHOD: The AAA bone was made into a block and a granule shape, and mixed with VEGF to prepare VEGF bone. Establishment of rat calvarium defect animal model, it is divided into 5 groups. With block bone, granular bone, block VEGF bone, granular VEGF bone was implanted in the bone defect for repair as the experimental group. The defect area was evaluated by histological and CBCT analysis 4 weeks postoperatively. RESULTS: Postoperative 4 weeks imaging results showed that there was no high-density shadow in the bone defect area of the blank group and the volume of high-density shadow in the bone defect area of the experimental group was different. Histological results showed that no osteoblasts were found in the blank group, and new bone was formed in the experimental group. The effect of bone formation in the granular bone was better than that in the block bone, and the amount of new bone formation in the VEGF bone group was higher than that of the single bone group. CONCLUSION: Granular bone has a better osteogenesis effect than block bone. The effect of allogeneic bone combined with VEGF in promoting new bone formation in the area of the bone defect is better than that of allogeneic bone alone. These results provide a theoretical and practical basis for its further clinical application.

13.
J Orthop Case Rep ; 14(9): 65-69, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39253644

ABSTRACT

Introduction: The induced membrane technique was initially described by Masquelet in 1986 as a treatment for tibia non-union. It then became an established method in the management of bone defects.A critical bone defect is defined by a gap larger than 25 mm, and so, has a higher probability of non-union. Many techniques have been described to resolve this problem such as segmental bone transport, free vascular fibula graft, non-vascular fibula graft, autogenous graft, or megaprothesis. Case Report: We present the case of a 37-year-old woman who presented a multi-fragmentary open fracture of the tibia and fibula bilaterally (Gustilo-Anderson III) after a high-velocity car accident. Conclusion: The aim of this article is to demonstrate that the use of a hybrid procedure combining the Masquelet technique with the Ilizarov external fixator and reamer-irrigator-aspirator can be an effective way to treat bone defect in an open tibial fracture classified as a Gustilo-Anderson III.

14.
Data Brief ; 56: 110836, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39263230

ABSTRACT

Humans primarily understand the world around them through visual perception and touch. As a result, visual and tactile information play crucial roles in the interaction between humans and their environment. In order to establish a correlation between what is seen and what is felt on the same object, particularly on flexible objects (such as textile, leather, skin etc.) which humans often access by touch to cooperatively determine their quality, the need for a new dataset that includes both visual and tactile information arises. This has motivated us to create a dataset that combines visual images and corresponding tactile data to explore the potential of cross-modal data fusion. We have chosen leather as our object of focus due to its widespread usage in everyday life. The dataset we propose consists of visual images depicting leather in various colours and displaying defects, alongside corresponding tactile data collected from the same region of the leather. Notably, the tactile data comprises components along the X, Y, and Z axes. To effectively demonstrate the relationship between visual and tactile data on the same object region, the tactile data is aligned with the visual data and visualized through interpolation. Considering the potential applications in computer vision, we have manually labelled the defect regions in each visual-tactile sample. Ultimately, the dataset comprises a total of 687 records. Each sample includes visual images, image representations of the tactile data (referred to as tactile images for simplicity), and segmentation images highlighting the defect regions, all with the same resolution.

15.
Cardiovasc Diagn Ther ; 14(4): 630-641, 2024 Aug 31.
Article in English | MEDLINE | ID: mdl-39263475

ABSTRACT

Background: Ventricular septal defect (VSD) is one of the most common congenital heart diseases. This study aims to evaluate the clinical value and benefit of transesophageal echocardiography (TEE) in transthoracic minimally invasive closure of VSDs using a completely biodegradable occluders, summarize the main points of surgical procedures, and analyze the follow-up results of short-term and medium-term treatment. Methods: We conducted a retrospective analysis of 24 pediatric cases of VSD, successfully treated with TEE-guided minimally invasive closure using fully biodegradable occluders between June 2019 and June 2022. The preoperative TEE meticulously examined the defect's location, size, and surrounding anatomical relationships, aiding in the selection of appropriate occluders and guiding the entire closure process. All patients were followed up for 1 year. Results: In our cohort, 13 cases were perimembranous inlet VSDs, and 11 involved VSDs with membranous aneurysm formation. The effective shunt size of VSD measured by TEE preoperatively ranged from 2.8 to 4.9 mm, with the defect located 2-6 mm from the aortic valve. Occluders used were 6-8 mm in diameter. All 24 procedures were successful. TEE confirmed that the occluders were tightly fitted at the edges of the VSDs. Twenty-three cases had no residual shunt post-surgery, while one case exhibited a small left-to-right shunt (<1.5 mm) at the occluder's edge. Follow-up was conducted on postoperative day 3, and in months 1, 3, 6, and 12, showing that the occluder's position remained normal in all patients. Except for one child who had a 1.2 mm left-to-right shunt at the edge of the occluder, no residual shunts were observed in the others. The occluder started to degrade from month 6, and the sizes of the left and right occluder discs were significantly smaller compared to those on postoperative day 3 (P=0.003). Conclusions: TEE-guided minimally invasive VSD occlusion using fully biodegradable occluders has the advantages of minimal trauma, high safety, and few complications, with satisfactory recent efficacy, and good prospects for clinical safety applications.

16.
Article in English | MEDLINE | ID: mdl-39263738

ABSTRACT

Alkali metal anodes paired with solid ion conductors offer promising avenues for enhancing battery energy density and safety. To facilitate rapid ion transport crucial for fast charging and discharging of batteries, it is essential to understand the behavior of point defects in these conductors. In this study, we investigate the heterogeneity of defect distribution in two prototypical solid ion conductors, Li3OCl and Li2PO2N (LiPON), by quantifying the defect formation energy (DFE) as a function of distance from the surface and interface through first-principles simulations. To simulate defects at the electrode-electrolyte interface, we perform calculations of Li+ vacancy in Li3OCl near its interface with lithium metal. Our results reveal a significant difference between the bulk and surface/interface DFE which could lead to defect aggregation/depletion near the surface/interface. Interestingly, while Li3OCl has a lower surface DFE than the bulk in most cases, LiPON follows the opposite trend with a higher surface DFE compared to the bulk. Due to this difference between bulk and surface DFE, the defect density can be up to 14 orders of magnitude higher at surfaces compared to the bulk. Further, we reveal that the DFE transition from surface/interface to bulk is precisely characterized by an exponentially decaying function. By incorporating this exponential trend, we develop a revised model for the average behavior of defects in solid ion conductors that offers a more accurate description of the influence of grain sizes. Surface effects dominate for grain sizes ≲1 µm, highlighting the importance of surface defect engineering and the DFE function for accurately capturing ion transport in devices. We further explore the kinetics of defect redistribution by calculating the migration barriers for defect movement between bulk and surfaces. We find a highly asymmetric energy landscape for the lithium vacancies, exhibiting lower migration barriers for movement toward the surface compared to the bulk, while interstitial defects exhibit comparable kinetics between surface and bulk regions. These insights highlight the importance of considering both thermodynamic and kinetic factors in designing solid ion conductors for improved ion transport at surfaces and interfaces.

17.
ACS Appl Mater Interfaces ; 16(36): 47902-47911, 2024 Sep 11.
Article in English | MEDLINE | ID: mdl-39223724

ABSTRACT

The application of shear horizontal (SH) guided wave transducers in high-temperature structural health monitoring (SHM) is a topic of significant interest across various industrial engineering sectors. In this study, we utilized the novelty piezoelectric crystal of near stoichiometric lithium niobate (NSLN), which exhibited a robust piezoelectric response (d15 = 77.6 pC/N@room temperature). Next, the pure thickness shear vibration mode d15' through size optimization was designed. It was demonstrated that the NSLN-based ultrasonic guided wave transducers utilizing the optimum d15' mode were proficient in transmitting and receiving pure fundamental SH wave (SH0 wave) along two orthogonal main directions (0° and 90°) over a wide frequency range (100-350 kHz), exhibiting strong response to the SH0 wave. Under the driving voltage of 100 V, the signal voltages of the NSLN-based transducer were found to be on the order of 200.3 and 11.8 mV at room temperature and high temperature of 650 °C, respectively. Moreover, the NSLN-based SH0 transducer showcased its better defect localization ability, and the signal-to-noise ratio (SNR) sensitivity of NSLN-based transducer was evaluated to be 16.1 dB at high temperature of 650 °C. To sum up, the ultrasonic wave transducer based on NSLN crystal demonstrated higher potential applications for in situ SHM under elevated temperatures.

18.
J Orthop Surg Res ; 19(1): 535, 2024 Sep 02.
Article in English | MEDLINE | ID: mdl-39223621

ABSTRACT

Degenerative disc disease is the leading cause of lower back and leg pain, considerably impacting daily life and incurring substantial medical expenses for those affected. The development of annulus fibrosus tissue engineering offers hope for treating this condition. However, the current annulus fibrosus tissue engineering scaffolds fail to accurately mimic the natural biological environment of the annulus fibrosus, resulting in limited secretion of extracellular matrix produced by the seeded cells and poor biomechanical properties of the constructed biomimetic annulus fibrosus tissue. This inability to match the biomechanical performance of the natural annulus fibrosus hinders the successful treatment of annulus fibrosus defects. In this study, we fabricated decellularized annulus fibrosus matrix (DAFM)/chitosan hydrogel-1 (DAFM: Chitosan 6:2) and DAFM/chitosan hydrogel-2 (DAFM: Chitosan 4:4) by varying the ratio of DAFM to chitosan. Rat annulus fibrosus (AF)-derived stem cells were cultured on these hydrogel scaffolds, and the cell morphology, AF-related gene expression, and Interleukin-6 (IL-6) levels were investigated. Additionally, magnetic resonance imaging, Hematoxylin and eosin staining, and Safranine and Fast Green staining were performed to evaluate the repair effect of the DAFM/chitosan hydrogels in vivo. The gene expression results showed that the expression of Collagen type I (Col-I), Collagen type I (Col-II), and aggrecan by annulus fibrosus stem cells (AFSCs) cultured on the DAFM/chitosan-1 hydrogel was higher compared with the DAFM/chitosan-2 hydrogel. Conversely, the expression of metalloproteinase-9 (MMP-9) and IL-6 was lower on the DAFM/chitosan-1 hydrogel compared with the DAFM/chitosan-2 hydrogel. In vivo, both the DAFM/chitosan-1 and DAFM/chitosan-2 hydrogels could partially repair large defects of the annulus fibrosus in rat tail vertebrae. In conclusion, the DAFM/chitosan-1 hydrogel could be regarded as a candidate scaffold material for the repair of annulus fibrosus defects, offering the potential for improved treatment outcomes.


Subject(s)
Annulus Fibrosus , Chitosan , Hydrogels , Rats, Sprague-Dawley , Animals , Rats , Tissue Scaffolds , Tissue Engineering/methods , Intervertebral Disc Degeneration/therapy , Male , Decellularized Extracellular Matrix , Cells, Cultured
19.
Article in English | MEDLINE | ID: mdl-39233533

ABSTRACT

OBJECTIVES: In gastroschisis, the intestines are exposed to amniotic fluid during pregnancy. The defect in the abdominal wall may also compress the mesentery and impair the intestinal blood supply. There is a varying degree of intestinal damage at birth. Complex gastroschisis is defined as gastroschisis with severe complications such as intestinal atresia, volvulus, necrosis and perforation. The aim of this study was to investigate long-term gastrointestinal morbidity and compare simple and complex cases. METHODS: A nation-wide retrospective cohort study with data from national registers was conducted. All children born with gastroschisis in Sweden from 1 January 1997 to 31 December 2016 were included in the study. Exposure was complex gastroschisis and the primary outcomes were intestinal failure and bowel obstruction. RESULTS: The study included 315 cases with gastroschisis, 260 classifieds as simple gastroschisis and 55 as complex. The median time to follow was 8 years. A significantly higher risk of developing intestinal failure (hazard ratio: 11.7) was found in complex cases. Nine percent of the complex cases underwent autologous gastrointestinal reconstructive surgery for intestinal failure, none of the simple cases did. The complex cases had a higher risk for bowel obstruction (hazard ratio: 4.3) with a higher proportion requiring surgery (18.2% vs. 6.9%) compared to simple cases. CONCLUSIONS: This nationwide study showed that the risk for intestinal failure and bowel obstruction is significantly higher for children with complex gastroschisis compared to simple gastroschisis. Most of the events occurred during the first 2 years of life.

20.
World J Pediatr Congenit Heart Surg ; : 21501351241269953, 2024 Sep 05.
Article in English | MEDLINE | ID: mdl-39234694

ABSTRACT

Patients with pulmonary atresia (PA) and a ventricular septal defect (VSD), similar to those with tetralogy of Fallot and PA without major aortopulmonary collateral arteries, lack antegrade pulmonary blood flow, and thus require a neonatal intervention for stabilization or augmentation of pulmonary blood flow. The role of ductal stenting in the management of these patients, and the current literature supporting it, will be reviewed.

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