ABSTRACT
We examined three cases where Kampo medicine had effects on palindromic rheumatism. All the patients are men with arthralgia accompanied by redness, fever, and swelling. All cases are RF negative. Cases 2 and 3 are brothers. Case 1: A 58-year-old patient with recurrent arthralgia on shoulders, hands, and legs for 30 years. Eppi-ka-jutsu-to was administrated for arthralgia. When discomfort of the hypochondrium (Kyokyokuman) was noted, the administration of Sho-Saiko-to reduced the symptom.<br>Case 2: A 40-year-old patient with recurrent arthralgia on shoulders, hands and legs for nine years. Eppi-ka-jutsu-to was administrated for arthralgia. When discomfort of the hypochondrium (Kyokyokuman) and contraction of the abdominal muscles (Fukuhikokyu) was noted, the administration of Eppi-ka-jutsu-to-go-Shigyaku-san-ryo was replaced, which reduced the symptoms.<br>Case 3: A 46-year-old patient with recurrent arthralgia on knees and fingers, and pain in hip joints. Eppi-ka-jutsu-to was administrated for arthralgia. When discomfort of the hypochondrium (Kyokyokuman) and contraction of the abdominal muscles (Fukuhikokyu) were noted, the administration of Shigyaku-san reduced the symptoms.<br>All cases were typical palindromic rheumatism, and Eppi-ka-jutsu-to was effective to a certain degree. Kampo diagnosis of Saiko (Saiko-sho) was made and additional Saiko-drugs (Saiko-zai) reduced the frequency, the degree, and the length of the period of symptoms.
ABSTRACT
Two cases of patients with acute burns, who were treated with Kampo formulas, are herein presented.<br>Case 1: A 53-year-old woman injured her left foot with boiled oil. She had been treated with an anti-inflammatory agent and dressing for four days before Kampo treatment. But the swelling of the foot became worse. Severe swelling, redness, heat and lots of exudate were apparent. She complained of thirst, which was probably due to loss of Shin'eki. Thus, Eppi-ka-jutsu-to was prescribed. Her symptoms improved within two days. Case 2: A 64-year-old-woman had facial burns from boiling water. She was in severe pain. Shiun-ko was applied topically, and Oren-gedoku-to with Kikyo-sekko was prescribed. The pain subsided promptly. On the next day, swelling, redness and heat were recognized. Eppi-ka-jutsu-to was effective. The local symptoms disappeared within a few days. Kampo treatment may be useful for relief of acute burn symptoms.
ABSTRACT
The hematological effects of Sokeikakketsu-to, Yokuinin-to, Keisi-ka-jutsubsu-to, Eppi-ka-jutsu-to, and Sairei-to observed on the AA rats were investigated. The time course of blood count and albumin, sialic acid and acid-soluble glycoprotein in the serum whs. were measured. Sokeikakketsu-to had the strongest anti-inflammatory effect on the improvement of Inflammatory Index Substances, platelets, and the Arthritis Score for changes in synovitis. Yokuinin-to was also effective. When these Kampo medicines were administered in the early stages of AA, Sokeikakketsu-to improved the AA signficantly. The results may suggest that Sokeikakketsu-to works for the control of autoimmunity. On the other hand, Keisi-ka-jutsubu-to aggravated the AA when it was administered in the early stages of the AA.
ABSTRACT
The effects of Sokei-kakketsu-to, Yokuinin-to, Keisi-ka-zyutsubu-to, Eppi-ka-jutsu-to, and Saireito extracts on Adjuvant-induced arthritis (AA) in rats were investigated. After administering AA, we measured the volume of rat hindpaw as the inflammation index, and observed the changes of synovitis histologically. Each extract showed different effects on AA rats. Yokuinin-to and Sokei-kakketsu-to had remarkable effects on inflammation and changed the histological observations of synovitis. Eppi-ka-jutsu-to also had effects on the uninjected hindpaw, but Keisi-ka-jutsubu-to and Sairei-to had no effect on hindpaw inflammation, nor did they change synovitis histologically.
ABSTRACT
In order to study the effects of Eppi-ka-jutsu-to on osteoarthritis of the knee, the author administered it to thirty subjects (nine males; twenty-one females) with osteoarthritis for eight weeks. Synovial fluid was obtained from all subjects before and after formula administration. All subjects had chronic swelling, tenderness and slight heat in the knee joints before therapy. Viewed from the change in score evaluation for knee osteoarthritis set by the Japanese orthopedic association, there was a significant improvement in pain on walking and joint effusion. In synovial fluid analysis, both the white blood cell count (especially the polymorphonuclear leukocyte count) and catalase activity were decreased significantly. This finding suggests that the sedation of inflammatory synovitis with Eppi-ka-jutsu-to might relieve the symptoms of knee osteoarthritis.
