ABSTRACT
BACKGROUND: Peptic ulcer (PU) is an abnormal phenomenon in which there is rupture of the mucosa of the digestive tract, which not only affects patients' normal life but also causes an economic burden due to its high medical costs. AIM: To investigate the efficacy of pantoprazole (PPZ) plus perforation repair in patients with PU and its effect on the stress response. METHODS: The study subjects were 108 PU patients admitted between July 2018 and July 2022, including 58 patients receiving PPZ plus perforation repair [research group (RG)] and 50 patients given simple perforation repair [control group (CG)]. The efficacy, somatostatin (SS) concentration, stress reaction [malondialdehyde (MDA), lipid peroxide (LPO)], inflammatory indices [tumor necrosis factor (TNF)-α, C-reactive protein (CRP), interleukin (IL)-1ß], recurrence, and complications (perforation, hemorrhage, and pyloric obstruction) were compared. RESULTS: The overall response rate was higher in the RG than in the CG. Patients in the RG had markedly elevated SS after treatment, which was higher than that of the CG, while MDA, LPO, TNF-, CRP, and IL-1ß were significantly reduced to lower levels than those in the CG. Lower recurrence and complication rates were identified in the RG group. CONCLUSION: Therefore, PPZ plus perforation repair is conducive to enhancing treatment outcomes in PU patients, reducing oxidative stress injury and excessive inflammatory reactions, and contributing to low recurrence and complication rates.
ABSTRACT
O objetivo deste artigo é verificar a percepção do tempo para os executivos brasileiros e a sua relação com o estresse. Os dados da pesquisa, que conjugou estratégia quantitativa e qualitativa, demonstram que o estresse está diretamente relacionado com o uso do tempo. Há diferença estatisticamente significativa quanto ao grau de satisfação no trabalho entre as pessoas que trabalham de 8 a 9 horas e as que trabalham 12 horas ou mais. Nesse último caso, a freqüência de sintomas de estresse é maior. O tempo dos altos executivos é abordado como algo autônomo, abstrato, independente, tal qual a concepção de tempo associada à concepção mecanicista da natureza. Não por acaso, o estresse já foi caracterizado como uma doença do tempo. (AU)
The aim of this article is to verify the perception of Brazilian executives about the relation between time and stress. The research that conjugated quantitative and qualitative data shows that stress is directly related with time schedule. There is significant statistical difference as to the satisfaction level at work among people that work from 8 to 9 hours daily and those who work 12 hours or more. In this last case the stress symptoms are larger. Top executives approach time as something autonomous, abstract, independent, associating time to the mechanical conception of nature. Not by chance,stress was already characterized as a disease of time. (AU)
Subject(s)
Humans , Burnout, Professional/psychology , Behavioral Medicine , Qualitative Research , Time PerceptionABSTRACT
O objetivo deste artigo é verificar a percepção do tempo para os executivosbrasileiros e a sua relação com o estresse. Os dados da pesquisa, queconjugou estratégia quantitativa e qualitativa, demonstram que o estresseestá diretamente relacionado com o uso do tempo. Há diferença estatisticamente significativa quanto ao grau de satisfação no trabalho entre as pessoas que trabalham de 8 a 9 horas e as que trabalham 12 horas ou mais. Nesse último caso, a freqüência de sintomas de estresse é maior. O tempo dos altos executivos é abordado como algo autônomo, abstrato, independente, tal qual a concepção de tempo associada à concepção mecanicista da natureza. Não por acaso, o estresse já foi caracterizado como uma doença do tempo...
The aim of this article is to verify the perception of Brazilian executivesabout the relation between time and stress. The research that conjugatedquantitative and qualitative data shows that stress is directly related with time schedule. There is significant statistical difference as to the satisfaction level at work among people that work from 8 to 9 hours daily and those who work 12 hours or more. In this last case the stress symptoms are larger. Top executives approach time as something autonomous, abstract, independent, associating time to the mechanical conception of nature. Not by chance,stress was already characterized as a disease of time...
