ABSTRACT
BACKGROUND: Solitary fibrous tumors of the pleura (SFTPs) are relatively rare tumors that originate from mesenchymal cells of submesothelial tissue of the pleura. Most patients with SFTPs are asymptomatic; however, pleuritic chest pain, cough, and dyspnea can develop. If hypoglycemia is associated with a solitary fibrous tumor, it is referred to as the Doege-Potter syndrome. CASE PRESENTATION: A 70-year-old man had visited our hospital with a chief complaint of dyspnea, and he was diagnosed as having a solitary fibrous tumor. A few years later, he developed hypoglycemia, and he underwent excision of the mass. CONCLUSION: Occasionally, SFTPs induce several paraneoplastic events, such as hypertrophic osteoarthropathy. We described here a patient with an SFTP with Doege-Potter syndrome who was successfully treated with complete resection. Although lesions can be histologically benign, they can clinically present with malignant features.
Subject(s)
Congenital Abnormalities/pathology , Kidney Diseases/congenital , Kidney/abnormalities , Pleura/pathology , Pleural Neoplasms/diagnosis , Solitary Fibrous Tumor, Pleural/diagnosis , Aged , Biopsy , Congenital Abnormalities/surgery , Diagnosis, Differential , Humans , Kidney/pathology , Kidney/surgery , Kidney Diseases/pathology , Kidney Diseases/surgery , Male , Pleura/surgery , Thoracotomy/methods , Tomography, X-Ray ComputedABSTRACT
Solitary fibrous tumor is an uncommon submesothelial mesenchymal neoplasm that primarily arises from the pleura. Most solitary fibrous tumors have a benign course, and the single most important predictor of the clinical outcome is the ability to excise the entire lesion. We experienced a case of CSF leakage through a subarachnoid-pleural fistula after resection of a malignant solitary fibrous tumor and the involved rib. We detected CSF leakage via performing CT myelography and we treated this case with hemilaminectomy and dura repair.
Subject(s)
Fistula , Myelography , Pleura , Ribs , Solitary Fibrous TumorsABSTRACT
Calcifying fibrous pseudotumors (CFP) are rare soft tissue tumors that have unique histopathologic features characterized by a dense hyalinized collagenous tissue interspersed with benign spindle cells, lymphoplasmacytic infiltrate, and psammomatous or dystrophic calcifications. We report here on a case of calcifying fibrous pseudotumors in the pleura and provide a literature review.
Subject(s)
Collagen , Hyalin , Pleura , Pleural DiseasesABSTRACT
Solitary fibrous tumor is an uncommon submesothelial mesenchymal neoplasm that arises primarily from the pleura. Extrapleural solitary fibrous tumors are rare. Solitary Fibrous tumors are often asymptomatic and discovered incidentally but may become symptomatic when vital structures are involved or they grow large. In general, solitary fibrous tumor is diagnosed on the basis of radiologic findings and its histologic features, with immunohistochemistry serving to support the diagnosis. Most solitary fibrous tumors pursue a benign course, and the single most important predictor of clinical outcome is the ability to excise the entire lesion. We experienced a case of intrapulmonary solitary tumor arising from the right lower lobe which was treated with wedge resection. We report this case of the patient.
Subject(s)
Humans , Diagnosis , Immunohistochemistry , Lung Neoplasms , Pleura , Solitary Fibrous TumorsABSTRACT
BACKGROUND: Solitary fibrous tumors of the pleura (SFTP) is one of rare neoplasms that originated from submesothelial mesenchyme. Clinical course or extent of surgical resection is not well known. MATERIAL ANDMETHOD: We retrospectively reviewed all the clinical records of the patients who had undergone surgical resection of benign and malignant SFTP. RESULT: Twenty two (male : female 14 : 8) patients were enrolled and mean age was 50.2 (range 25~83). Number of symptomatic patients at the time of diagnosis was 13 (59%) and the most common symptom was dyspnea. Operative approach was carried out through thoracotomy (n=14) or video-assisted thoracic surgery (n=8). Mass excision was performed in 12 cases and en bloc resection including adjacent structure in 10 cases. In all cases complete resection was performed. There was no operative mortality. Malignant SFTP were 11 cases and benign SFTP 11 cases. Local recurrences (n=2) or distant metastasis (n=6) occurred only in malignant SFTP. CONCLUSION: Number of symptomatic patients, en bloc resection, and recurrence was more in malignant SFTP. Although complete surgical resection is known as treatment of choice for SFTP, further study should be performed about systemic therapeutic modalities pre- or postoperatively to control recurrence and metastasis.
Subject(s)
Female , Humans , Diagnosis , Dyspnea , Mesoderm , Mortality , Neoplasm Metastasis , Pleura , Pleural Neoplasms , Recurrence , Retrospective Studies , Solitary Fibrous Tumors , Thoracic Surgery, Video-Assisted , ThoracotomyABSTRACT
We present a case of a 47-year-old woman with benign solitary fibrous tumor of the pleura originated in the diaphragm which was discovered incidentally on a chest radiograph. Chest radiograph, sonograph, computed tomographic scan and magnetic resonance image studies proved a well circumscribed and lobulated fibrous tumor of the pleura. During the subsequent right thoracotomy, the tumor was found to be encapsulated and consisted of firm mass. It was connected to the diaphragm with 5x4 cm area by pedicle. Most of the tumor was free of adhesion. It was excised completely together with attached diaphragm. The tumor measured 23.5x3.5x8.0 cm and the pathologic diagnosis was benign solitary fibrous tumor and the attached diaphragm was free of disease.
Subject(s)
Female , Humans , Middle Aged , Diagnosis , Diaphragm , Pleura , Pleural Neoplasms , Radiography, Thoracic , Solitary Fibrous Tumor, Pleural , Solitary Fibrous Tumors , ThoracotomyABSTRACT
Solitary fibrous tumors of the serosal cavities are rare and usually occur in the visceral or parietal pleura, but they have also been observed in the mediastinum, pericardium, peritoneum, lung parenchyma, orbit, and the meninges. The histological variability of these tumors may contribute to the difficulty in diagnosing these neoplasms, especially when they arise in the mediastinum and extrathoracic sites. The clinical behavior of the tumor is unpredictable. Some tumors that appear histologically benign may behave aggressively. The incidence of aggressive behavior is variously reported as between 13 and 23% of cases in most large series. This report is a case review in a 53-year-old female patient who had re-excision of histologically benign, recurrent solitary fibrous tumor, 1, 6, 11, and 14 years after the initial operation.
Subject(s)
Female , Humans , Middle Aged , Incidence , Lung , Mediastinal Neoplasms , Mediastinum , Meninges , Orbit , Pericardium , Peritoneum , Pleura , Solitary Fibrous TumorsABSTRACT
It suggested that localized fibrous tumor of the pleura originated from a primitive submesothelial mesenchymal cell. The criteria used for a judgment of malignancy were high cellularity and mitotic activity(more than four mitotic figures per 10 high-power fields), pleomorphism, hemorrhage, and necrosis. This 62 years female was admitted with dyspnea and cough. Chest X-ray and CT scan showed a huge mass in right thorax. A 23X18X12 cm, 2 Kg sized mass was excised, and it was collase the right lower lobe and right middle lobe and was adhered to the diaphragm. Pathologically, the tumor was composed high cellularity, fascicle of the spindle cells, and high mitotic numbers(27 mitosis/10HPF). Immunohistochemically, it was positive for vimentin and CD34. This tumor was diagnosised to the malignancy localized fibrous tumor. We experience a case of pleural malignant fibrous tumor and report this case with the review of literature.
