Comparison of early period sexual function parameters between surgical repair and conservative treatment after penile fracture / Comparación de los parámetros de función sexual en el período temprano entre la reparación quirúrgica y el tratamiento conservador después de una fractura de pene

Introduction and objectives: Comparison of early period sexual function parameters in patients who had surgical repair and conservative follow-up after penile fracture and the evaluation of surgical intervention time on these parameters were planned in this study. Materials and methods: Total of 26 patients who were treated for penile fracture were evaluated. 19 patients had surgical repair and 7 patients had conservative treatment.Sexual function and erectile dysfunction (ED) degree of the patients before penile fracture and in the 12th week after fracture were evaluated with 5-question International Index of Erectile Function (IIEF-5) questionnaire, Erection Hardness Score (EHS), Sexual Encounter Profile(SEP) 2 and SEP 3. Parameters showing sexual function before and after the fracture were compared. Results: In both groups, a significant change was detected in IIEF-5 score, EHS, SEP-2 and SEP-3 parameters of the patients measured after penile fracture compared to the values before the fracture (all parameters, p<0.05). No difference was detected in the parameters measured before and after the fracture among surgical repair and conservative treatment groups (all parameters p>0.05). Mean time passing until the surgery after fracture was measured as 9.6±6.85h in 19 patients who had surgery. Conclusion: A difference wasn’t detected in sexual parameters in conservative treatment and surgical repair groups in this study. As a significant decrease was observed in sexual function parameters even in conservative treatment cases without sudden detumescence and tunica albuginea rupturing, we think that quick surgical exploration would be useful in cases considered to have penile fracture. (AU)

Introducción y objetivos: En este estudio se planificó la comparación de los parámetros de función sexual en el período temprano en pacientes sometidos a reparación quirúrgica y seguimiento conservador después de una fractura de pene y la evaluación del tiempo de intervención quirúrgica sobre estos parámetros. Materiales y métodos: Se evaluaron un total de 26 pacientes que fueron tratados por fractura de pene: 19 fueron sometidos a reparación quirúrgica y 7 tuvieron un seguimiento conservador. La función sexual y el grado de disfunción eréctil de los pacientes antes de la fractura de pene y en la semana 12 después de la fractura se evaluaron con el cuestionario International Index of Erectile Function de 5 preguntas (IIEF-5), el Erection Hardness Score (EHS), y el Sexual Encounter Profile (SEP) 2 y SEP 3. Se compararon los parámetros que muestran la función sexual antes y después de la fractura. Resultados: En ambos grupos se detectó un cambio significativo en la puntuación IIEF-5 y los parámetros EHS, SEP 2 y SEP 3 de los pacientes medidos después de la fractura de pene en comparación con los valores antes de la fractura (todos los parámetros, p<0,05). No se detectaron diferencias en los parámetros medidos antes y después de la fractura entre los grupos de reparación quirúrgica y tratamiento conservador (todos los parámetros p>0,05). El tiempo medio transcurrido hasta la cirugía después de la fractura se midió como 9,6±6,85h en los 19 pacientes intervenidos. Conclusión: No se detectaron diferencias en los parámetros sexuales entre los grupos de observancia conservadora y reparación quirúrgica en este estudio. Como se observó una disminución significativa de los parámetros de función sexual incluso en casos de seguimiento conservador sin detumescencia súbita y desgarro de la túnica albugínea, pensamos que la exploración quirúrgica rápida sería útil en los casos en los que se considere que tienen fractura de pene. (AU)

Comparison of early period sexual function parameters between surgical repair and conservative treatment after penile fracture.

INTRODUCTION AND OBJECTIVES: Comparison of early period sexual function parameters in patients who had surgical repair and conservative follow-up after penile fracture and the evaluation of surgical intervention time on these parameters were planned in this study. MATERIALS AND METHODS: Total of 26 patients who were treated for penile fracture were evaluated. 19 patients had surgical repair and 7 patients had conservative treatment. Sexual function and erectile dysfunction (ED) degree of the patients before penile fracture and in the 12th week after fracture were evaluated with 5-question International Index of Erectile Function (IIEF-5) questionnaire, Erection Hardness Score (EHS), Sexual Encounter Profile(SEP) 2 and SEP 3. Parameters showing sexual function before and after the fracture were compared. RESULTS: In both groups, a significant change was detected in IIEF-5 score, EHS, SEP-2 and SEP-3 parameters of the patients measured after penile fracture compared to the values before the fracture (all parameters, p<0.05). No difference was detected in the parameters measured before and after the fracture among surgical repair and conservative treatment groups (all parameters p>0.05). Mean time passing until the surgery after fracture was measured as 9.6±6.85h in 19 patients who had surgery. CONCLUSION: A difference wasn't detected in sexual parameters in conservative treatment and surgical repair groups in this study. As a significant decrease was observed in sexual function parameters even in conservative treatment cases without sudden detumescence and tunica albuginea rupturing, we think that quick surgical exploration would be useful in cases considered to have penile fracture.

Effect of dexpanthenol on wound healing in penile fracture model: An experimental study.

OBJECTIVES: In the present study, we aimed to investigate the effect of dexpanthenol on wound healing at the histopathological level on cavernous tissue. MATERIALS AND METHODS: Forty-four Wistar albino rats weighing 220-250 g were used. The rats were randomly divided into four groups as Group B, Group S, Group LD, and Group SD. In Group B, the incision was not repaired and left to secondary healing. In Group S, the incision line was repaired with 5/0 polyglactin suture. In Group LD, 0.25 mg/kg dexpanthenol was applied subcutaneously below the repaired wound region once a day during 14 days. In Group SD, 500 mg dexpanthenol was applied intraperitoneally once a day during 14 days. RESULTS: No fibrosis was observed in 8 (80%) rats in group SD. Fibrosis rates were significantly lower in Group SD compared to Group B, Group S, and Group LD (p = 0.013, p = 0.005, and p = 0.003, respectively). CONCLUSION: Systemic dexpanthenol administration significantly decreased fibrosis in penile fracture model on rats.

OBJETIVO: En el estudio actual nuestro objetivo fue investigar el efecto del dexpantenol en la cicatrización de heridas a nivel histopatológico en el tejido cavernoso. MÉTODOS: se utilizaron 44 ratas Wistar albinas con un peso de 220-250 g. Las ratas se dividieron aleatoriamente en 4 grupos como grupo B, grupo S, grupo LD y grupo SD. En el grupo B, la incisión no se reparó y se dejó para la cicatrización secundaria. En el grupo S, la línea de incisión se reparó con sutura de poliglactina 5/0. En el grupo LD, se aplicaron 0.25 mg/kg de dexpentanol por vía subcutánea debajo de la región de la herida reparada una vez al día durante 14 días. En el grupo SD se aplicaron 500 mg de dexpentanol por vía intraperitoneal una vez al día durante 14 días. RESULTADOS: No se observó fibrosis en 8 (80%) ratas del grupo SD. Las tasas de fibrosis fueron significativamente más bajas en el grupo SD en comparación con el grupo B, el grupo S y el grupo LD (todos p < 0.05). CONCLUSIÓN: La administración sistémica de dexpantenol disminuyó significativamente la fibrosis en el modelo de fractura de pene en ratas.

Long term complications of penile fracture repair: Erectile dysfunction and penile curvature / Complicaciones a largo plazo de la reparación de fractura; disfunción eréctil y curvatura de pene

Objective: To determine the factors that cause erectile dysfunction and penile curvature after repair of penile fracture (PF).Methods: Data from 25 patients who underwent PF repair was retrospectively analyzed. PF was diagnosed by examining patients’ medical histories and performing physical examinations. All patients underwent immediate PF repair. All patients filled out the International Index of Erectile Function (IIEF-5) form and penile curvature was examined.Results: The median age of patients at the time of surgery and the median follow-up duration were 46 years (22–60 years) and 95 months (12–156 months), respectively. Two of the patients had concomitant urethral injury. At the final follow up, erectile dysfunction (ED) was present in 13 patients (52%). Among these patients, 9 patients (36%) had mild ED and 4 patients (16%) had moderate ED. With a univariate analysis, age and penile curvature were significantly associated with ED (p=0.008 and p=0.039, respectively). With a multivariate analysis, age was independently associated with ED (p=0.048, odds ratio=1.104, 95% confidence interval 1.000–1.218). The IIEF-5 scores correlated with age (p=0.009, r=0.510). Seven patients (28%) had penile curvature and one patient underwent penile plication surgery.Conclusion: After PF repair, age is the only risk factor for ED and penile curvature rarely requires surgical treatment. (AU)

Objetivo: Determinar los factores que causan disfunción eréctil y curvatura de pene tras una reparación de fractura de pene (FP).Métodos: Se analizaron retrospectivamente los datos de 25 pacientes sometidos a reparación de FP. Se diagnosticó FP examinando las historias clínicas de los pacientes y realizando exploraciones físicas. Se sometió a todos los pacientes a reparación inmediata de FP. Todos los pacientes completaron el formulario IIEF-5 (International Index of Erectile Function), y se examinó la curvatura de pene.Resultados: La edad media de los pacientes en el momento de la cirugía y la duración media del seguimiento fueron de 46 años(22–60 años) y 95 meses (12–156 meses), respectivamente. Dos pacientes tuvieron lesión uretral concomitante. Al finalizar el seguimiento se presentó disfunción eréctil (DE) en 13 pacientes (52%). Entre estos pacientes, nueve (36%) tuvieron DE leve y cuatro (16%) DE moderada. Con un análisis univariante, la edad y la curvatura de pene estuvieron significativamente asociadas a DE (p = 0,008 y p = 0,039, respectivamente). Con un análisis multivariante, la edad estuvo independientemente asociada a DE (p = 0,048, odds ratio = 1,104, 95% de intervalo de confianza 1,000–1,218). Las puntuaciones IIEF-5 se correlacionaron con la edad (p = 0,009, r = 0,510). Siete pacientes (28%) tuvieron curvatura de pene y un paciente fue sometido a cirugía de plicatura de pene.Conclusión: Tras la reparación de FP, la edad es el único factor de riesgo de DE, y la curvatura de pene raramente requiere tratamiento quirúrgico. (AU)

Long term complications of penile fracture repair: Erectile dysfunction and penile curvature.

OBJECTIVE: To determine the factors that cause erectile dysfunction and penile curvature after repair of penile fracture (PF). METHODS: Data from 25 patients who underwent PF repair was retrospectively analyzed. PF was diagnosed by examining patients' medical histories and performing physical examinations. All patients underwent immediate PF repair. All patients filled out the International Index of Erectile Function (IIEF-5) form and penile curvature was examined. RESULTS: The median age of patients at the time of surgery and the median follow-up duration were 46 years (22-60 years) and 95 months (12-156 months), respectively. Two of the patients had concomitant urethral injury. At the final follow up, erectile dysfunction (ED) was present in 13 patients (52%). Among these patients, 9 patients (36%) had mild ED and 4 patients (16%) had moderate ED. With a univariate analysis, age and penile curvature were significantly associated with ED (p=0.008 and p=0.039, respectively). With a multivariate analysis, age was independently associated with ED (p=0.048, odds ratio=1.104, 95% confidence interval 1.000-1.218). The IIEF-5 scores correlated with age (p=0.009, r=0.510). Seven patients (28%) had penile curvature and one patient underwent penile plication surgery. CONCLUSION: After PF repair, age is the only risk factor for ED and penile curvature rarely requires surgical treatment.

Diseño y evaluación de un modelo de simulación de fractura de pene / Design and assessment of a penile fracture simulation model

Objetivo: Diseñar y evaluar un nuevo modelo de simulación de fractura de pene para la enseñanza de su reparación.MétodosHemos utilizado un simulador de circuncisión validado para crear un nuevo modelo. El prepucio para circuncisión se dividió en 2 mitades. Se creó un corte transversal («simulación de fractura») en una parte de la primera mitad del prepucio (imitando la «túnica») y se colocó sobre el modelo de pene. Se colocó una pastilla de gelatina roja («coágulo») debajo del corte. Se aplicó un segundo trozo para completar el prepucio por encima y cubrir el defecto. El modelo fue evaluado por los participantes y docentes expertos del boot camp de simulación de urología. La evaluación se realizó mediante un cuestionario con escala de Likert de 5 puntos. Los datos se analizaron mediante Microsoft Excel e IBM SPSS Statistics V25. La correlación intraclase se calculó mediante «un modelo aleatorio unidireccional».ResultadosVeintidós estudiantes de urología y 4 expertos participaron en la evaluación. La mayoría de los aprendices estuvieron muy de acuerdo (59%, n=13) en la utilidad del modelo para la formación, y los expertos también estuvieron de acuerdo en el 75% de los casos. Tanto alumnos (68%, n=14) como docentes (75%) consideraron correcta la apariencia de la fractura del pene. En general, la capacidad del modelo para representar una simulación realista de la tarea fue considerada excelente por el 23% de los participantes y buena por el 64%. Tras la simulación los alumnos afirmaron tener una mayor confianza en el manejo de este tipo de casos. Las principales dificultades señaladas estaban relacionadas con los planos fasciales y la uretra.ConclusiónEste es el primer modelo de simulación para la reparación de fracturas de pene y ha demostrado su validez en un boot camp de urología nacional. (AU)

Objective: To design and assess a novel penile fracture simulation model for teaching penile fracture repair.MethodsWe used a validated circumcision simulator to create a model. Foreskin for a circumcision was divided into two halves. A transverse slit (“simulated fracture”) was created on one part of the first half of the foreskin (mimicking “tunica”) and was applied over the penile model. A red jelly tablet (“clot”) was placed underneath the cut. A second full-length of foreskin was applied over it to cover the defect. The model was assessed by participants and expert faculty at the Urology Simulation Boot Camp. Evaluation was performed using a 5-point Likert Scale questionnaire. Data was analysed using Microsoft Excel and IBM SPSS Statistics V25. The intra-class correlation was calculated using a “One-way random model”.ResultsTwenty-two urology trainees and four experts participated in the evaluation. The majority of trainees strongly agreed (59%, n=13) the model is useful for training with experts similarly agreeing in 75% of cases. The appearance of penile fracture was considered good by both trainees (68%, n=14) and faculty (75%). Overall, the ability of the model to represent a realistic simulation of the task was considered excellent by 23% of participants and good by 64%. Personal confidence after simulation in managing a similar situation was considered high among trainees. The main difficulties reported were related to fascial planes and urethra.ConclusionThis is the first simulation model for penile fracture repair and has demonstrated face validity at a national urology bootcamp. (AU)

Design and assessment of a penile fracture simulation model.

OBJECTIVE: To design and assess a novel penile fracture simulation model for teaching penile fracture repair. METHODS: We used a validated circumcision simulator to create a model. Foreskin for a circumcision was divided into two halves. A transverse slit ("simulated fracture") was created on one part of the first half of the foreskin (mimicking "tunica") and was applied over the penile model. A red jelly tablet ("clot") was placed underneath the cut. A second full-length of foreskin was applied over it to cover the defect. The model was assessed by participants and expert faculty at the Urology Simulation Boot Camp. Evaluation was performed using a 5-point Likert Scale questionnaire. Data was analysed using Microsoft Excel and IBM SPSS Statistics V25. The intra-class correlation was calculated using a "One-way random model". RESULTS: Twenty-two urology trainees and four experts participated in the evaluation. The majority of trainees strongly agreed (59%, n = 13) the model is useful for training with experts similarly agreeing in 75% of cases. The appearance of penile fracture was considered good by both trainees (68%, n = 14) and faculty (75%). Overall, the ability of the model to represent a realistic simulation of the task was considered excellent by 23% of participants and good by 64%. Personal confidence after simulation in managing a similar situation was considered high among trainees. The main difficulties reported were related to fascial planes and urethra. CONCLUSION: This is the first simulation model for penile fracture repair and has demonstrated face validity at a national urology bootcamp.

Design and assessment of a penile fracture simulation model. / Diseño y evaluación de un modelo de simulación de fractura de pene.

OBJECTIVE: To design and assess a novel penile fracture simulation model for teaching penile fracture repair. METHODS: We used a validated circumcision simulator to create a model. Foreskin for a circumcision was divided into two halves. A transverse slit ("simulated fracture") was created on one part of the first half of the foreskin (mimicking "tunica") and was applied over the penile model. A red jelly tablet ("clot") was placed underneath the cut. A second full-length of foreskin was applied over it to cover the defect. The model was assessed by participants and expert faculty at the Urology Simulation Boot Camp. Evaluation was performed using a 5-point Likert Scale questionnaire. Data was analysed using Microsoft Excel and IBM SPSS Statistics V25. The intra-class correlation was calculated using a "One-way random model". RESULTS: Twenty-two urology trainees and four experts participated in the evaluation. The majority of trainees strongly agreed (59%, n=13) the model is useful for training with experts similarly agreeing in 75% of cases. The appearance of penile fracture was considered good by both trainees (68%, n=14) and faculty (75%). Overall, the ability of the model to represent a realistic simulation of the task was considered excellent by 23% of participants and good by 64%. Personal confidence after simulation in managing a similar situation was considered high among trainees. The main difficulties reported were related to fascial planes and urethra. CONCLUSION: This is the first simulation model for penile fracture repair and has demonstrated face validity at a national urology bootcamp.

Cavernosopatía Traumática Aguda (CTA) trauma peneano en un grupo de 38 pacientes en un consultorio de medicina sexual durante 20 años de experiencia (1998-2018) / Acute Traumatic Cavernosopathy Penile Trauma in a Group of 38 Patients in a Sexual Medicine Clinic during 20 Years of Experience (1998-2018) Juan Fernando Uribe A

Introducción El trauma de pene tiene una variedad de presentaciones, no siempre de origen sexual con diversas implicaciones anatómicas y funcionales para él. Objetivo Describir los hallazgos en un grupo de pacientes de "Cavernosopatía traumática aguda" (CTA), desde el punto de vista clínico y ecográfico y sus desenlaces. Métodos Se realizó un estudio retrospectivo de un grupo de 38 pacientes que consultaron por CTA en un período de 20 años (1998-2018) en una consulta de medicina sexual en Medellín-Colombia. La condición para ser incluidos, era el antecedente en el tiempo de un trauma agudo y mayor del pene. Se evaluaron el tipo de trauma y variables relacionadas (crack audible, hematoma, fractura albugínea, ruptura del ligamento suspensorio, necesidad de cirugía); hallazgos clínicos (curvaturas, escotaduras, acortamiento); hallazgos ecográficos (Fibrosis peneana, fugas venosas) y otros desenlaces (disfunción eréctil). El estudio contó con la aprobación del comité de ética en investigación del HPTU. Resultados Se estudiaron 38 pacientes con diagnóstico de CTA. Edad de consulta: 42 y edad del trauma 38,7 años, promedio. Trauma sexual (TS): 23 pacientes (60,5%), No sexual (TNS): 15 pacientes (39,4%). Hematomas: 22 (57,8%); fractura albugínea: 16 (42,1%); ruptura del ligamento suspensorio: 2 (5,2%); curvatura secundaria: 14 (36,8%); nódulos palpables: 13 (34,2%); acortamiento: 11 (28,9%); crack audible: 13 (34,2%); algún grado de disfunción eréctil: 26 (68,4%); necesidad de cirugía urgente: 6 (15,78%). En los 31 (81,5%) pacientes que tuvieron una ECO peneana como parte de su estudio tenemos, hallazgo de fibrosis: 25/31 (80,6%); fugas venosas cavernosas: 5/31 (16,1%) e hipervascularización 10/31 (32,2%). Conclusiones La Cavernosopatía traumática aguda (CTA) es una denominación adecuada para el síndrome que desencadena un trauma peneano agudo, que puede incluir secuelas como fibrosis peneana (hasta el 80%), curvaturas secundarias (hasta el 38%), acortamiento, fugas venosas y disfunción eréctil (hasta 70% de los casos). Entre 6/10 de esos traumas, son de índole sexual y el resto son un grupo variopinto de traumas (automovilísticos, deportivos, quemaduras, ataques de animales)

Introduction Penis trauma has a variety of presentations, not always of sexual origin with various anatomical and functional implications for the penis. ObjectiveTo describe the findings in a group of patients of "acute traumatic Cavernosophaty", from the clinical and echographics point of view and their outcomes. Methods A retrospective study of a group of 38 patients who consulted by CTA in a period of 20 years (1998-2018) in a sexual medicine clinic in Medellin, Colombia, was conducted. The condition to be included was the antecedent in time of an acute and major trauma of the penis. The type of trauma and related variables were evaluated (audible crack, hematoma, albuginea fracture, rupture of the suspensory ligament, need for surgery); clinical findings (curvatures, notches, shortening); ultrasound findings (penile fibrosis, venous leaks) and other outcomes (erectile dysfunction). The study was approved by the research ethics committee of the HPTU. Results Thirty-eight patients with diagnosis of CTA were studied. Age of consultation: 42 and age of the trauma 38.7 years, average. Sexual trauma (TS): 23 patients (60.5%), Non-sexual (TNS): 15 patients (39.4%). Haematoma: 22 (57.8%); albugineal fracture: 16 (42.1%); rupture of the suspensory ligament: 2 (5.2%); secondary curvature: 14 (36.8%); palpable nodules: 13 (34.2%); shortening: 11 (28.9%); audible crack: 13 (34.2%); some degree of erectile dysfunction: 26 (68.4%); need for urgent surgery: 6 (15.78%). In the 31 (81.5%) patients who had a penile ECO as part of their study: fibrosis finding: 25/31 (80.6%); venous cavernous leaks: 5/31 (16.1%) and hypervascularization 10/31 (32.2%). Conclusions Acute traumatic cavernosopathy is an appropriate name for the syndrome that triggers a greater and acute penile trauma, which can include sequelae such as penile fibrosis (up to 80%), secondary curvatures (up to 38%), shortening, venous leaks and erectile dysfunction (up to 70% of cases). 6/10 of these traumas are of a sexual nature and the rest are a motley group of traumas (car, sports, burns, animal attacks).

Tratamiento quirúrgico de la fractura de pene / Surgical treatment of the penis fracture

Se describe el caso clínico de un paciente de 39 años de edad, sin antecedentes patológicos personales y procedente de un área rural, que fue operado en el Hospital General Peltier de la República de Djibouti por habérsele fracturado el cuerpo cavernoso del pene durante el coito, lo cual obligó a realizarle una incisión circunferencial subcoronal, que finalmente garantizó buenos resultados estéticos y funcionales de ese órgano genital externo.

The case report of a 39 year-old patient, without personal pathological history and coming from a rural area, who was surgically treated at the Peltier General Hospital of the Djibouti Republic due to a fracture in the corpus cavernosum of penis during the coitus, that forced to make him a circunferencial subcoronal incision which finally guaranteed good aesthetic and functional results of that external genital organ.

Tratamiento quirúrgico de la fractura de pene / Surgical treatment of the penis fracture

Se describe el caso clínico de un paciente de 39 años de edad, sin antecedentes patológicos personales y procedente de un área rural, que fue operado en el Hospital General Peltier de la República de Djibouti por habérsele fracturado el cuerpo cavernoso del pene durante el coito, lo cual obligó a realizarle una incisión circunferencial subcoronal, que finalmente garantizó buenos resultados estéticos y funcionales de ese órgano genital externo(AU)

The case report of a 39 year-old patient, without personal pathological history and coming from a rural area, who was surgically treated at the Peltier General Hospital of the Djibouti Republic due to a fracture in the corpus cavernosum of penis during the coitus, that forced to make him a circunferencial subcoronal incision which finally guaranteed good aesthetic and functional results of that external genital organ(AU)