Heavy episodic drinking among French adolescents between 2005 and 2022: decreasing prevalence rates and increased risks.

OBJECTIVE: To study the prevalence of alcohol use among French adolescents over time and factors associated with heavy episodic drinking (HED) among drinkers. METHOD: Our analysis relies on six waves of a standardized cross, sectional survey conducted in mainland France between 2005 and 2022. The overall sample size comprises 179905 adolescents aged 17 (90166 males and 89739 females). Two outcomes were considered: declaring past month HED (at least one) and repeated HED (at least three) in the past month between 2005 and 2022. Relative risks and probabilities according to years of survey, gender and frequency of alcohol use (past 30 days) were estimated using modified Poisson regressions controlling for grade retention, schooling, living out of parental household, socioeconomic status, and other substance (tobacco, cannabis, other illicit substances) use. RESULTS: Despite a steady decline in alcohol use among French adolescents over the past two decades, the prevalence of HED still concerned one, third of 17-year-olds in 2022. The reduction in alcohol use conceals an increased likelihood of HED among occasional drinkers (<10 times a month). Moreover, the probability of HED among females is similar to that of males, or even higher depending on the frequency of use. CONCLUSIONS: HED is becoming an increasingly common behavior among adolescent drinkers. The decline in prevalence conceals a homogenization of behavior between genders. Our results also question underage access to alcohol, despite increasing legal restrictions. These results support general prevention in early adolescence aimed at all drinkers, and not only at the most frequent or "at-risk" drinkers.

Analysis of college students' attitudes toward the use of ChatGPT in their academic activities: effect of intent to use, verification of information and responsible use.

BACKGROUND: In recent years, the use of artificial intelligence (AI) in education has increased worldwide. The launch of the ChatGPT-3 posed great challenges for higher education, given its popularity among university students. The present study aimed to analyze the attitudes of university students toward the use of ChatGPTs in their academic activities. METHOD: This study was oriented toward a quantitative approach and had a nonexperimental design. An online survey was administered to the 499 participants. RESULTS: The findings of this study revealed a significant association between various factors and attitudes toward the use of the ChatGPT. The higher beta coefficients for responsible use (ß=0.806***), the intention to use frequently (ß=0.509***), and acceptance (ß=0.441***) suggested that these are the strongest predictors of a positive attitude toward ChatGPT. The presence of positive emotions (ß=0.418***) also plays a significant role. Conversely, risk (ß=-0.104**) and boredom (ß=-0.145**) demonstrate a negative yet less decisive influence. These results provide an enhanced understanding of how students perceive and utilize ChatGPTs, supporting a unified theory of user behavior in educational technology contexts. CONCLUSION: Ease of use, intention to use frequently, acceptance, and intention to verify information influenced the behavioral intention to use ChatGPT responsibly. On the one hand, this study provides suggestions for HEIs to improve their educational curricula to take advantage of the potential benefits of AI and contribute to AI literacy.

Uso y conocimiento tradicional de plantas medicinales en comunidades de Villa Corzo, Chiapas, México / Use and traditional knowledge of medicinal plants in communities of Villa Corzo, Chiapas, Mexico

The use and knowledge of native and naturalized medicinal plants were evaluated in four communities of Villa Corzo, Chiapas, Mexico. The information was obtained through semi - structured surveys conducted with 1 18 people of different age and gender categories. To determine the most important plant species, indexes of value and frequency of use were generated. Seventy - nine species of 49 families were recorded, as well as their use in the treatment of various disea ses according to local knowledge. The species with the highest value of use were Aloe vera (L.) Burm. f., Verbena officinalis L. (verbena), Ocimum basilicum L. (basil) and Psidium guajava L. (guava). (guava). The most important families by number of specie s used were, in order of importance: Asteraceae and Rutaceae with five species Lamiaceae, Fabaceae and Rosaceae with four species each.

Se evaluaron el uso y conocimiento de las plantas medicinales nativas y naturalizadas en cuatro comunidades de Villa Corzo, Chiapas, México. La información se obtuvo a través de encuestas semiestructuradas realizadas a 118 personas de distintas categorías de edad y género. Para determinar las especies de plantas más importantes se generaron índices de valor y frecuencia de uso. Se registraron 79 especies de 49 familias, así como su uso en el tratamiento de diversas enfermedades de acuerdo al conocimiento local. Las especies con mayor valor de uso fueron Aloe vera (L.) Burm. f. (sábila), Verbena officinalis L. (verbena), Ocimum basilicum L. (albahaca) y Psidium guajava L. (guayaba). Las familias más importantes por el número de especies utilizadas fueron, en orden de importancia: Asteraceae y Rutaceae con cinco especies, Lamiaceae, Fabaceae y Rosaceae con cuatro especies cada una.

Cigarette and ENDS dual use longitudinal transitions among adults in the Population Assessment of Tobacco and Health (PATH) Study, Waves 4-5 (2016-2019).

Introduction: The study assessed longitudinal transitions among adult (18 and older) past 30-day daily and non-daily dual users of cigarettes and electronic nicotine delivery systems (ENDS). Methods: Using data from Wave 4 (W4; 2016/17) and Wave 5 (W5; 2018/19) of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative, longitudinal cohort study of US adults, multivariable regressions were conducted among W4 dual users of cigarettes and ENDS to examine past 30-day cigarette smoking at W5. The study also analyzed changes in frequency of past 30-day smoking and cigarettes smoked per day between W4 and W5, stratified by W4/W5 daily/non-daily ENDS use among W4 daily and non-daily cigarette smokers. Results: Among W4 dual users, those smoking daily and using ENDS non-daily had higher odds of daily cigarette smoking at W5 than daily users of both products (AOR: 2.32, 95 % CI: 1.38-3.90). W4 daily smokers who used ENDS daily at Wave 5 smoked cigarettes on fewer days at Wave 5 than W4 daily smokers who were either daily ENDS users at Wave 4 (B = -4.59; SE = 1.43, p < 0.01) or non-daily ENDS users at Wave 4 (B = -4.55; SE = 1.24, p < 0.001). Among W4 non-daily cigarette smokers, W4 non-daily ENDS users who used daily at W5 smoked cigarettes on fewer days (B = -4.04, SE = 1.82) at W5 than those who were non-daily ENDS users at W4 and W5. Conclusions: Findings highlight the importance of frequency of ENDS use in reducing cigarette smoking and could inform smoking cessation interventions among daily cigarette smokers.

Factors determining the frequency of optical coherence tomography and intravascular ultrasound use in patients treated with percutaneous coronary interventions in recent years: Analysis based on a large national registry.

BACKGROUND: Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have demonstrated improvement in the clinical outcome of patients undergoing percutaneous coronary intervention (PCI). AIMS: We aimed to examine the frequency of implementing OCT and IVUS during coronary angiography (CA) and PCI in everyday practice in Poland. Factors related to the more common choice of these imaging techniques were determined. METHODS: Data from the Polish National Registry of Percutaneous Coronary Interventions (ORPKI) were procured for analysis. Between January 2014 and December 2021, we extracted data on 1 452 135 CAs, 11 710 using IVUS (0.8%) and 1471 with OCT (0.1%) and 838 297 PCIs, 15 436 with IVUS (1.8%) and 1680 with OCT (0.2%). We assessed the determining factors for applying IVUS and OCT via multiple regression logistics models. RESULTS: The frequency of applying IVUS during CAs and PCIs increased significantly between the years 2014 and 2021. In 2021, it reached 1.54% for CAs and 4.42% for PCIs, while for OCT, there was a rise regarding the CA group, namely 0.13% in 2021, and, in the PCI group, 0.43%. Age was one of the factors significantly associated with the frequency of using IVUS/OCT during CA/PCI, which was confirmed by multivariate analysis (Odds ratio: 0.981 for IVUS and 0.973 for OCT use with PCI). CONCLUSION: The frequency at which IVUS and OCT were used has undergone a significant increase in previous years. This increase can be largely attributed to the current reimbursement policies. Further improvement is required for this frequency to be at a satisfactory level.

Consumer habits and practices for cosmetics and personal care products in Singapore: An online survey.

Understanding trends in habits and practices of cosmetics and personal care products is essential for the assessment of product exposure and simultaneously, the establishment of safe use levels for incorporated ingredients. To date, most exposure data is limited to European and USA populations, with data on Asian-specific habits and practices lacking. This data gap needs to be filled as evidence has shown that there is a large variation in product use behaviors between consumers, across and within populations. Moreover, there is a need to seek a more efficient approach of data collection. Conventional methods of collecting habits and practices data require extensive effort and are generally cost and time intensive. In this publication, we demonstrate the feasibility of employing a rapid and cost-effective online survey approach to gather habits and practices for Southeast Asia, specifically Singapore. We describe the methodology and display the type of habits and practices data that can be gathered through this approach. Although certain limitations exist, this approach can be used to effectively collect preliminary product use data across regions and different product categories.

Emoji-SP, the Spanish emoji database: Visual complexity, familiarity, frequency of use, clarity, and emotional valence and arousal norms for 1031 emojis.

This article presents subjective norms for 1031 emojis in six dimensions: visual complexity, familiarity, frequency of use, clarity, emotional valence, and emotional arousal. This is the largest normative study conducted so far that relies on subjective ratings. Unlike the few existing normative studies, which mainly comprise face emojis, here we present a wide range of emoji categories. We also examine the correlations between the dimensions assessed. Our results show that, in terms of their affective properties, emojis are analogous to other stimuli, such as words, showing the expected U-shaped relationship between valence and arousal. The relationship between affective properties and other dimensions (e.g., between valence and familiarity) is also similar to the relationship observed in words, in the sense that positively valenced emojis are more familiar than negative ones. These findings suggest that emojis are suitable stimuli for studying affective processing. Emoji-SP will be highly valuable for researchers of various fields interested in emojis, including computer science, communication, linguistics, and psychology. The full set of norms is available at: https://osf.io/dtfjv/ .

Mediating Effect of Upper Limb Use on the Relationship Between Upper Limb Performance and Activities of Daily Living: A Longitudinal Mediation Analysis.

INTRODUCTION: Upper limb performance, frequency of upper limb use, and psychological factors are associated with activities of daily living (ADLs) after stroke. We performed a mediation analysis to investigate how the frequency of upper limb use and some psychological factors mediate the relationship between upper limb performance and ADLs. METHODS: Twenty-two patients with stroke were included in this longitudinal study. We utilized the frequency of upper limb use outcome measures (amount of use and quality of motion of the motor activity log), psychological factors outcome measures (General Self-Efficacy Scale), upper limb performance outcome measures (Fugl-Meyer Assessment (FMA)), and ADLs outcome measure (Functional Independence Measure (FIM) motor subscale (M)). Mediation analysis with a bootstrap sampling procedure was used to assess the indirect effects. RESULTS: Mediation analysis showed that the FMA, as measured by the FIM (M), had significant indirect effects on the amount of use (95% bootstrapped confidence interval (CI): 0.36-2.42) and quality of motion (95% bootstrapped CI: 0.06-1.88). The relationship between upper limb performance and ADLs was mediated by the frequency of upper limb use. CONCLUSION: Our findings suggest that improving the frequency of upper limb use may accelerate post-stroke recovery.

Sex- and Dose-Dependent Differences in the Development of an Addiction-Like Phenotype Following Extended-Access Fentanyl Self-Administration.

Opioid use disorder (OUD) is a major epidemic in the United States, and fentanyl is a major culprit. The National Institute on Drug Abuse has highlighted an urgent need for research on the risks and outcomes of OUD with fentanyl; a better understanding of sex/gender differences is also critically needed given that the opioid epidemic has been particularly impactful on women. In response to this need, we developed a rat model of OUD with fentanyl and showed that sex impacts relapse vulnerability following extended-access self-administration under a low fentanyl dose. Here, our goal was to determine sex differences across a broad dose range, including high doses expected to maximize the expression of addiction-like features (e.g., vulnerability to relapse and physical dependence). Male and female rats were assigned to self-administer one of four fentanyl doses (0.25, 0.75, 1.5, and 3.0 µg/kg/infusion), and once they acquired, they were given extended (24-h/day), intermittent access (2, 5 min trials/h, fixed-ratio 1) to fentanyl for 10 days. Physical dependence (spontaneous weight loss) was assessed during early withdrawal, and relapse vulnerability was assessed on withdrawal day 15 using an extinction/cue-induced reinstatement procedure. Despite markedly higher intake in the high- versus low-dose groups, each group responded similarly during relapse testing (extinction and cue-induced reinstatement). However, number of infusions, or frequency of use, during extended access was predictive of later vulnerability to relapse, whereas total intake impacted physical dependence given that weight loss only occurred following the discontinuation of fentanyl self-administration at the three highest doses. Females self-administered more fentanyl each day and within each binge (active trial), and had longer lasting weight loss during withdrawal than males. Relapse vulnerability was also higher in females than males and highest in females tested during estrus. These findings indicate that sex is an important risk factor for patterns and levels of fentanyl intake, relapse, and physical dependence, and while fentanyl intake predicts physical dependence, frequency of use predicts relapse.

Can Habits Impede Creativity by Inducing Fixation?

In a competitive and ever-changing world, the ability to generate outstanding ideas is crucial. However, this process can be impeded by factors such as fixation on ideas that emerged through prior experience. The aim of the present study was to shed light on the fixating effect of habits on creativity. To this end, healthy young adults were asked to generate alternative uses for items that differed in their frequency of use in the Alternative Uses Task (a standardized test for divergent thinking). We predicted that frequent past use of an item would lead to the formation of stimulus-response associations between the item and its most frequent use(s) and thereby hinder idea generation. Indeed, individuals were less flexible (but more fluent) in generating ideas for frequently used items than for unknown items. Additionally, we found that subjective automaticity of idea generation was negatively related with flexibility. Finally, we investigated whether individual differences in general habit tendency influence creativity, by relating performance on the Slips-of-Action task (an outcome devaluation paradigm extensively used in habit research) to performance on the Alternative Uses Task, the Candle Problem (a classic convergent thinking task) and two puzzles (non-conventional problem-solving tasks). While we did not find a significant relationship between habit tendency and the Alternative Uses Task or the Candle Problem scores, the tendency to rely on habits predicted probability to succeed and latency to solve one of the puzzles: less habit-prone participants were more likely to solve it and to do so faster. In conclusion, our study provides evidence for the notion that habits can negatively impact creativity and opens promising future avenues of research in this field.

The relationship of frequency of cocaine use to substance and psychiatric disorders in the U.S. general population.

BACKGROUND: In clinical trials of pharmacotherapy for substance use, abstinence is the primary endpoint accepted by regulatory agencies. However, this endpoint could be overly restrictive, impeding efforts to identify effective medications for cocaine use disorder. To examine non-abstinent gradations in cocaine use as potential indicators of improvement, we investigated the relationship of frequency of cocaine use to clinical correlates in national survey data. METHODS: Lifetime cocaine users (n = 2501) were interviewed in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC) in 2001-2002 and re-interviewed in 2004-2005. Adjusted odds ratios (aORs) indicated associations between heaviest frequency of cocaine use and use of other substances, DSM-IV substance use disorders, psychiatric disorders, and change between 2001-2002 and 2004-2005. The reference category for all aORs was non-users. RESULTS: Greater lifetime cocaine use frequency was associated with lifetime cocaine, alcohol, and cannabis dependence (aOR for a linear trend = 2.80, 1.22, 1.22, respectively) and past-year cocaine, alcohol, and cannabis dependence (aOR = 1.78, 1.13, 1.16, respectively). Greater lifetime cocaine use frequency was associated with past-year depressive, panic, and generalized anxiety disorders (aOR = 1.07, 1.09, 1.12, respectively). Among cocaine users in 2001-2002, compared to the reference group using less than monthly, use ≥1x/week and use 1-3 times a month was associated with cocaine use disorder in 2004-2005 (aOR = 2.13 and aOR = 1.67, respectively). CONCLUSION: Gradations in risk for dependence on cocaine, other substances and psychiatric disorders by frequency of cocaine use indicates a promising direction for more sensitive outcome measures of treatment effects on cocaine outcomes than binary indicators (e.g., any use vs. none). Study results add to findings suggesting that non-abstinent measures might be useful indicators of treatment efficacy in clinical trials.

Disparities in the frequency of tobacco products use by sexual identity status.

BACKGROUND: Largely absent from the literature are studies examining differences in tobacco use frequency among sexual minority populations versus heterosexuals. The current study examined the frequency of tobacco product use (i.e., cigarette, e-cigarettes and cigars, smokeless tobacco, hookah, and heated tobacco products) among sexual minority students versus heterosexuals (straight). METHODS: Data from the 2020 National Youth Tobacco Survey (n = 14,531) were analyzed to examine the association between sexual identity (lesbian or gay, bisexual, not sure, and heterosexual or straight) and tobacco use frequency. Negative binomial regression and zero-inflated negative binomial models were used to assess the association between sexual identity and each tobacco use frequency among current and ever users. RESULTS: Current e-cigarettes users who identified as gay or lesbian used e-cigarette more frequently than heterosexual students. Multivariable count regression analysis showed that the e-cigarette use frequency in the past 30 days was significantly higher for gays or lesbians (IRR 1.45, 95% CI, 1.19-1.76) compared to heterosexuals. Similarly, gay or lesbian students who were current hookah users on average reported 81% more days of hookah use (IRR, 1.81, 95% CI, 1.08-3.03). The frequency of cigarette smoking was also significantly higher among bisexual cigarette smokers. No significant differences were found in other tobacco product use frequencies between sexual minority and heterosexual youths. CONCLUSION: Sexual identity was associated with tobacco use frequency, especially for e-cigarettes and hookah. Elevated tobacco use among sexual minority groups deserves special consideration among a population group that is highly vulnerable to marketing and advertisement targeting.

Associations between self-reported cannabis use frequency, potency, and cannabis/health metrics.

BACKGROUND: Research shows that cannabis use frequency is associated with cannabis dependence and health metrics. However, much less is known about how self-reported cannabis potency (THC and CBD) may be associated with the same metrics, and whether any associations exist after accounting for frequency of cannabis use. Moreover, even less is known about how these relations may differ across cannabis product forms. This exploratory study examined 1) associations between cannabis frequency, potency, and cannabis/health metrics, and 2) whether associations between potency and cannabis/health metrics remained after controlling for frequency of use. METHODS: Using a sample of adult recreational cannabis users in Colorado (N = 300), we tested the relationship between self-reported cannabis use metrics of frequency and potency of flower, edible, and concentrate products with separate measures of problematic cannabis use (i.e., dependence, withdrawal, craving), depression, anxiety, and general perceived health. RESULTS: Greater frequency of flower and concentrate (but not edible) use were associated with greater problematic cannabis use, and greater concentrate use frequency was also associated with more mental health problems. Partial correlations controlling for average frequency of use across all product forms and CBD potency per product showed that one significant association between THC potency and cannabis/health metrics remained (i.e., higher THC concentrate potency with better health), and one emerged (i.e., higher THC concentrate potency with lower cannabis withdrawal). CONCLUSIONS: Frequency of use is reliably associated with problematic cannabis use for flower and concentrates, but it did not account for all observed associations in this study. Differences in patterns of associations between frequency and potency and cannabis/health metrics across cannabis forms suggest a need for better understanding user reports of THC and CBD potency, individual differences among users, and improved measurement.

The history of number words in the world's languages-what have we learnt so far?

For over 100 years, researchers from various disciplines have been enthralled and occupied by the study of number words. This article discusses implications for the study of deep history and human evolution that arise from this body of work. Phylogenetic modelling shows that low-limit number words are preserved across thousands of years, a pattern consistently observed in several language families. Cross-linguistic frequencies of use and experimental studies also point to widespread homogeneity in the use of number words. Yet linguistic typology and field documentation reports caution against positing a privileged linguistic category for number words, showing a wealth of variation in how number words are encoded across the world. In contrast with low-limit numbers, the higher numbers are characterized by a rapid and morphologically consistent pattern of expansion, and behave like grammatical phrasal units, following language-internal rules. Taken together, the evidence suggests that numbers are at the cross-roads of language history. For languages that do have productive and consistent number systems, numerals one to five are among the most reliable available linguistic fossils of deep history, defying change yet still bearing the marks of the past, while higher numbers emerge as innovative tools looking to the future, derived using language-internal patterns and created to meet the needs of modern speakers. This article is part of the theme issue 'Reconstructing prehistoric languages'.

Cannabis use in a sample of Aristotle University of Thessaloniki students: a pilot cross-sectional study.

BACKGROUND: Cannabis is the most widespread illicit drug among young adults globally. This study aimed to detect the extent of cannabis use in the study population and its impact on users' lives. We hypothesized that early cannabis use would significantly predict later high-risk use. METHODS: An online cross-sectional study using a self-administered questionnaire was conducted in December 2021, aiming to explore the extent of cannabis use among students and detect changes in behavior and impact on their lives. The results were analyzed statistically and correlated. RESULTS: Out of the 297 enrolled participants with a mean age of 21.0 ± 2.1 years, 101 (33.9 %) had used cannabis at least once (50 males). The mean age at first cannabis use was 18.5 ± 2.11 years. Over 90 % reported easy access to it. Behavioral changes following use were reported by 41.6 %, but none except one sought help. Age at first cannabis use was negatively correlated with past-month and past-year use. Cannabis use before midday was positively correlated with age on the first try. DISCUSSION: The prevalence of cannabis use was higher than the European average. Confirming the study's hypothesis, the younger the age at first use, the heavier the past-year and past-month use, which also agrees with previous studies. Cannabis consumption before noon was linked to increased use, and alarmingly, there was reluctance to seek help despite a high proportion of behavioral changes after use. CONCLUSION: As the legislation on the use of cannabis changes rapidly, and given the increasing popularity of cannabis, there is a need for continued research on how various factors differentially impact its use. HIPPOKRATIA 2021, 25 (4):162-168.

Sources of drug acquisition among females and males in the European Web Survey on Drugs.

BACKGROUND: Social networks determine the availability of drugs, which in turn affects use patterns. Yet, there is some limited evidence that as frequency of drug use increases, people who use drugs increasingly utilize drug dealers. Further, females more often report receiving drugs for free. Studies on these two phenomena are limited by the substances they examine and the countries in which they have been conducted, and they have not been considered together. We examine whether gender differences in sources is moderated by increased frequency of use across four different substances in a web survey of sixteen European countries. METHODS: The European Web Survey on Drugs was collected from 2016-2018 among the national partners of the European Monitoring Centre for Drugs and Drug Addiction. Individuals who use drugs in sixteen European countries completed an online survey. For herbal cannabis, cannabis resin, cocaine, and MDMA, we examine drug acquisition sources by gender and frequency of use. Sources include through dealers and sharing or free, as well as growing and online markets for cannabis. We model each source with logistic regression with chained multiple imputation and a country fixed-effect and clustered standard errors. RESULTS: Across all substances, females who use drugs at low frequencies had significantly lower probabilities than males in using dealers; however, females were equally likely to use dealers when use is frequent. The probability of acquiring drugs for free was higher for females except among those who use most frequently, where the difference became non-significant except for herbal cannabis. CONCLUSIONS: Females and males use dealers to acquire illicit drugs at similar rates when use is more frequent. Except for highest frequency use, females are typically more likely than males to acquire drugs for free. Examinations of supply should consider these gendered differences in acquisition.

Frequency of cannabis use and alcohol-associated adverse effects in a representative sample of U.S. adolescents and youth (2002-2014) a cross-sectional study.

BACKGROUND: While the link between frequent cannabis use and alcohol use disorders is well documented, it is not clear whether alcohol drinkers who use cannabis less frequently are also vulnerable to alcohol use disorders. We estimate the association of frequency of past 12-months cannabis use with alcohol-associated adverse effects variables in the same time frame: alcohol dependence, heavy drinking, driving under alcohol influence, alcohol-related interpersonal problems, use after interpersonal problems, alcohol-related risky behaviors, and alcohol-related legal problems. METHODS: We analyzed data from U.S. individuals aged 12 to 25 years who participated in annual, cross-sectional U.S. National Surveys on Drug Use and Health from 2002 to 2014. Logistic regression models were used to examine the association of cannabis use with six alcohol-associated adverse effects variables. Frequency of cannabis use served as the primary independent variable, and were divided into four categories: frequent use (21-30 days per month), less frequent use (1-20 days per month), no use over the past 12 months, and no lifetime cannabis use. Alcohol dependence and six alcohol-associated adverse effects variables served as our primary outcomes. RESULTS: The study included 465,090 respondents aged 12 to 25 years, among all past-year cannabis users, (47.5%) were less frequent (1-20 days/month) users. Less frequent cannabis use was highest among male, 15-25-year-olds, and non-Hispanic white 11.8, 84 and 10.6%, respectively. In adjusted models, past-year less frequent cannabis use (1-20 days/month) was significantly associated with past-year alcohol dependence (adjusted odds ratio aOR 5.57, 95% confidence interval (CI) 5.5-6.4); heavy drinking in the past-year (aOR 3.41, 95% CI 3.2-3.5); alcohol-related interpersonal problems in the past-year (aOR 7.33, 95% CI 7.0-7.5); use after interpersonal problems (aOR 5.17, 95% CI 4.8-5.5); alcohol-related risky behaviors (aOR 7.29, 95% CI 7.0-7.5), and, driving under influence of alcohol (aOR 7.19, 95% CI 6.9-7.4). No cannabis use past-year were more likely to report alcohol dependence (aOR 2.81, 95% CI 2.6-3) compared with no lifetime cannabis use. CONCLUSION: These findings indicated that within the general population, not only frequent cannabis user (21-30 days per month) but even less frequent cannabis use (1-20 days/month) was significantly associated with past-year alcohol dependence and alcohol-associated adverse effects than no lifetime cannabis use. These adverse alcohol-related outcomes associated with less frequent cannabis use, should be taken under careful consideration in alcohol use disorder treatment setting and policy planning.

Recommended motor assessments based on psychometric properties in individuals with dementia: a systematic review.

BACKGROUND: Motor assessments are important to determine effectiveness of physical activity in individuals with dementia (IWD). However, inappropriate and non-standardised assessments without sound psychometric properties have been used. This systematic review aims to examine psychometric properties of motor assessments in IWD combined with frequency of use and effect sizes and to provide recommendations based on observed findings.We performed a two-stage systematic literature search using Pubmed, Web of Science, Cochrane Library, ALOIS, and Scopus (inception - July/September 2018, English and German). The first search purposed to identify motor assessments used in randomised controlled trials assessing effectiveness of physical activity in IWD and to display their frequency of use and effect sizes. The second search focused on psychometric properties considering influence of severity and aetiology of dementia and cueing on test-retest reliability. Two reviewers independently extracted and analysed findings of eligible studies in a narrative synthesis. RESULTS: Literature searches identified 46 randomised controlled trials and 21 psychometric property studies. While insufficient information was available for validity, we observed sufficient inter-rater and relative test-retest reliability but unacceptable absolute test-retest reliability for most assessments. Combining these findings with frequency of use and effect sizes, we recommend Functional Reach Test, Groningen Meander Walking Test (time), Berg Balance Scale, Performance Oriented Mobility Assessment, Timed Up & Go Test, instrumented gait analysis (spatiotemporal parameters), Sit-to-Stand assessments (repetitions> 1), and 6-min walk test. It is important to consider that severity and aetiology of dementia and cueing influenced test-retest reliability of some assessments. CONCLUSION: This review establishes an important foundation for future investigations. Sufficient relative reliability supports the conclusiveness of recommended assessments at group level, while unacceptable absolute reliability advices caution in assessing intra-individual changes. Moreover, influences on test-retest reliability suggest tailoring assessments and instructions to IWD and applying cueing only where it is inevitable. Considering heterogeneity of included studies and insufficient examination in various areas, these recommendations are not comprehensive. Further research, especially on validity and influences on test-retest reliability, as well as standardisation and development of tailored assessments for IWD is crucial.This systematic review was registered in PROSPERO (CRD42018105399).

Saber etnobotánico, riqueza y valor de uso de plantas medicinales en Monterrey, Villa Corzo, Chiapas (México) / Ethnobotanical knowledge, richness and use value of medicinal plants in the community "Monterrey", Villa Corzo, Chiapas (México)

Se registraron 73 especies de plantas medicinales naturalizadas o nativas de la comunidad Monterrey, municipio de Villa Corzo, Chiapas, México. Para el levantamiento de la información, se aplicó una entrevista semiestructurada a una muestra de 119 personas, categorizadas por edad y sexo. Se determinó la familia botánica de cada una de las plantas identificadas, así como el índice de riqueza de conocimiento, el valor de uso y la frecuencia de uso. Dentro de las especies más usadas se encuentran la Verbena (Verbena officinalis L.), la Manzanilla (Chamaemelum nobile L.) y la Albahaca (Ocimum basilicum L.), la Sábila (Aloe barbadensis Miller) y la Ruda (Ruta chalepensis L.), que presentan el mayor índice de riqueza de conocimiento, así como de valor de uso. Las familias más representadas por especies de uso botánico fueron Asteraceae con diez especies, Fabaceae, Lamiaceae, Poaceae con cuatro y Annonaceae, Apiaceae, Lauraceae y Rubiaceae, con tres especies.

Seventy-three species of naturalized or native medicinal plants of the Monterrey community, municipality of Villa Corzo, Chiapas, Mexico were registered. A semi-structured interview was applied to a sample of 119 people, categorized by age and sex. The botanical family of each identified plants was determined, as well as the index of knowledge richness, the use value and the frequency of use. Among the most used species are the Verbena (Verbena officinalis L), the Chamomile (Chamaemelum nobile L.) and the Basil (Ocimum basilicum L.), the Aloe (Aloe barbedensis Miller) and the Rue (Ruta chalepensis L.), which showed the highest rate of richness of knowledge, as well as use value. The botanical families most represented by species of medicinal use were Asteraceae with ten species, Fabaceae, Lamiaceae, Poaceae with four and Annonaceae, Apiaceae, Lauraceae and Rubiaceae, with three species.