Progress in global drug resistance patterns and drug resistance mechanisms of Mycoplasma pneumon-iae / 中华微生物学和免疫学杂志

Mycoplasma pneumoniae (M. pneumoniae) is one of the predominant pathogenic bacte-ria causing community acquired pneumonia. An epidemic of M. pneumoniae infection occurs every three to seven years worldwide. It can cause a variety of clinical symptoms. Since 2000, macrolide-resistant M. pneu-moniae strains have become increasingly common in many countries around the world and the drug resistance rate has reached as high as 100% in some area, which has posed a great threat to human health. This paper will review the status and mechanism of drug resistance in M. pneumoniae.