ABSTRACT
Introducción: No existe consenso sobre qué gráfica neonatal es mejor utilizar en niños con muy bajo peso al nacer (MBPN). El objetivo del estudio fue comparar las gráficas de Fenton 2013 e Intergrowth-21st (IW-21) con base en su capacidad predictora de la somatometría a los dos años, así como analizar factores relacionados con talla baja a los dos años. Material y métodos: Cohorte de niños con MBPN nacidos entre 2002-2017. Se analizó la asociación entre la somatometría neonatal (z-score por Fenton e IW-21) y el riesgo de talla baja (< -2 desviación estándar [DS]), perímetro craneal < -2 DS y desnutrición a los 2 años (IMC < -2 DS) (gráficas OMS). Resultados: Se incluyeron 513 niños con una edad gestacional media de 30,05 ± 2,5 semanas. El z-score del peso al nacimiento y al alta por Fenton y por IW-21 resultaron útiles para predecir riesgo de talla baja y desnutrición a los dos años (sin diferencias en el AUC de las curvas ROC), siendo el z-score al alta útil además para predecir perímetro craneal < -2D. A los dos años, la prevalencia de talla baja, perímetro craneal < -2 DS, y desnutrición fue del 17,2, 4,1 y 6,1%, respectivamente. El bajo peso para la edad gestacional y la duración del ingreso neonatal se identificaron como factores de riesgo independientes para talla baja a los dos años. Conclusiones: El z-score peso al alta resulta útil para predecir riesgo de talla baja, desnutrición y perímetro craneal < -2 DS a los dos años en niños con muy bajo peso al nacer, sin diferencias estadísticas entre utilizar las gráficas de Fenton o IW-21. (AU)
Introduction: There is no consensus on which neonatal chart is best to use in very low birth weight (VLBW) infants. The aim of the study was to compare the Fenton 2013 and Intergrowth-21st (IW-21) charts based on their predictive ability for somatometry at 2 years, as well as to analyze factors related to short stature at 2 years. Material and methods: Cohort of children with VLBW born in 20022017. Association between neonatal somatometry (z-score by Fenton and IW-21) and risk of short stature (< −2 DS), head circumference < −2 DS and malnutrition at 2 years (BMI < −2 DS) was analyzed (WHO charts). Results: 513 children with a mean gestational age of 30.05 ± 2.5 weeks were included. Birth and discharge weight z-score by Fenton and IW-21 were useful for predicting risk of short stature and malnutrition at 2 years (without differences in the AUC of the ROC curves). Weight z-score at discharge was also useful for predicting head circumference < −2 DS. At 2 years, prevalence of short stature, head circumference < −2 DS, and malnutrition was 17.2, 4.1, and 6.1%, respectively. Low weight for gestational age and length of stay were identified as independent risk factors for short stature at 2 years. Conclusions: Discharge weight z-score is useful for predicting risk of short stature, malnutrition and head circumference < −2 DS at 2 years in very low birth weight children, with no statistical difference between using Fenton or IW-21 charts. (AU)
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , History, 21st Century , Infant, Very Low Birth Weight/growth & development , Growth Charts , Infant, Premature , Epidemiology, Descriptive , Retrospective Studies , MalnutritionABSTRACT
INTRODUCTION: There is no consensus on which neonatal chart is best to use in very low birth weight (VLBW) infants. The aim of the study was to compare the Fenton 2013 and Intergrowth-21st (IW-21) charts based on their predictive ability for somatometry at 2 years, as well as to analyze factors related to short stature at 2 years. MATERIAL AND METHODS: Cohort of children with VLBW born between 2002 and 2017. Association between neonatal somatometry (z-score by Fenton and IW-21) and risk of short stature (<-2 DS), head circumference <-2 DS and malnutrition at 2 years (BMI < -2 DS) was analyzed (WHO charts). RESULTS: 513 children with a mean gestational age of 30.05 ± 2.5 weeks were included. Birth and discharge weight z-score by Fenton and IW-21 were useful for predicting risk of short stature and malnutrition at 2 years (without differences in the AUC of the ROC curves). Weight z-score at discharge was also useful for predicting head circumference < -2 DS. At 2 years, prevalence of short stature, head circumference < -2 DS, and malnutrition was 17.2, 4.1, and 6.1%, respectively. Low weight for gestational age and length of stay were identified as independent risk factors for short stature at 2 years. CONCLUSIONS: Discharge weight z-score is useful for predicting risk of short stature, malnutrition and head circumference < -2 DS at 2 years in very low birth weight children, with no statistical difference between using Fenton or IW-21 charts.
Subject(s)
Dwarfism , Malnutrition , Birth Weight , Child , Female , Gestational Age , Growth Charts , Humans , Infant , Infant, Newborn , Infant, Small for Gestational AgeABSTRACT
Introducción: no existe consenso sobre la gráfica idónea para monitorizar el crecimiento de prematuros, sin embargo, Fenton es la más difundida. Desde el aparecimiento de INTERGROWTH-21st ésta se perfila como una herramienta eficaz. Nuestro objetivo fue comparar INTERGROWTH-21st y Fenton en la valoración antropométrica de prematuros. Población y Métodos: estudio transversal que analizó datos antropométricos de prematuros entre enero de 2014 a diciembre de 2016 mediante la revisión de registros. La clasificación se realizó por edad gestacional y sexo usando Fenton y se compararon con INTERGROWTH-21st categorizando los percentiles 10, 50 y 90. Se realizaron pruebas de correlación y concordancia (p < 0.05, intervalo de confianza 95%). Se mantuvieron los respectivos lineamientos éticos. Resultados: en 232 prematuros la prevalencia de peso bajo fue de 13.7% con Fenton y 15.9% con INTERGROWTH-21st y para peso elevado 2.5% y 6% respectivamente. Presentaron una concordancia de 0.7 peso y perímetro cefálico. De 194 prematuros adecuados para la edad gestacional por Fenton, INTERGROWTH-21st clasificó al 4% como bajos y altos y el resto como adecuados. Existió correlación positiva en los tres parámetros antropométricos. Tomando como estándar a INTERGROWTH-21st y como criterio a evaluar a Fenton, la especificidad fue mayor que la sensibilidad en la antropometría baja (98.4 y 78.3 peso, 98.3 y 62.5 longitud y 100 y 64.2 perímetro cefálico) y elevada (100 y 42.8 peso, 97.5 y 22.2 longitud y 96.3 y 70 perímetro cefálico). Conclusión: Fenton clasifica con menor frecuencia pesos bajos y elevados para la edad gestacional en relación a INTERGROWTH-21st.
Introduction: there is no consensus on the ideal graph to monitor the growth of premature infants; however, the Fenton graph is the most widespread. Since the appearance of the INTERGROWTH-21st chart, this is emerging as an effective tool. Our objective was to compare INTERGROWTH-21st and Fenton in the anthropometric assessment of premature infants. Population and methods: a cross-sectional study that analyzed anthropometric data of premature infants between January 2014 and December 2016 by reviewing records. The classification was made by gestational age and sex using Fenton and was compared with INTERGROWTH-21st by categorizing the 10th, 50th and 90th percentiles. Correlation and concordance tests were performed (p <0.005, 95% confidence interval). The respective ethical guidelines were maintained. Results: in 232 preterm infants the prevalence of low weight was 13.7% with Fenton and 15.9% with INTERGROWTH-21st and for high weight 2.5% and 6% respectively. Weight and cephalic perimeter presented a concordance of 0.7. Of 194 premature babies suitable for gestational age by Fenton, INTERGROWTH-21st classified 4% as low and high, the rest as adequate. There was positive correlation in the three anthropometric parameters. Taking as standard INTERGROWTH-21st and as a criterion to evaluate Fenton, the specificity was greater than the sensitivity in low anthropometry (98.4 and 78.3 weight, 98.3 and 62.5 length, 100 and 64.2 cephalic perimeter) and high (100 and 42.8 weight, 97.5 and 22.2 length, 96.3 and 70 cephalic perimeter). Conclusion: Fenton classified less frequently low and high weights for gestational age in relation to INTERGROWTH-21st.
