ABSTRACT
ABSTRACT Graphium basitruncatum, a synanamorph of Pseudoallescheria has been rarely reported in human infections. We report a case of subcutaneous phaeohyphomycosis caused by this fungus in a heart transplant recipient. We also describe the phenotypic, molecular methods and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) used to achieve isolate identification.
Subject(s)
Humans , Male , Middle Aged , Ascomycota/genetics , Dermatomycoses/microbiology , Transplant Recipients , Phenotype , Ascomycota/classification , Polymerase Chain Reaction , Heart Transplantation , Immunocompromised HostABSTRACT
Graphium basitruncatum, a synanamorph of Pseudoallescheria has been rarely reported in human infections. We report a case of subcutaneous phaeohyphomycosis caused by this fungus in a heart transplant recipient. We also describe the phenotypic, molecular methods and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) used to achieve isolate identification.
Subject(s)
Ascomycota/genetics , Dermatomycoses/microbiology , Heart Transplantation , Transplant Recipients , Ascomycota/classification , Humans , Immunocompromised Host , Male , Middle Aged , Phenotype , Polymerase Chain ReactionABSTRACT
Graphium basitruncatum is genetically and morphologically distinct from other Graphium and Scedosporium species, and has been reported only once previously as a cause of human disease. We report a case of Graphium basitruncatum fungemia in a two year old child with dyskeratosis congenita who underwent stem cell transplantation two months prior to infection.
