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1.
Child Abuse Negl ; 154: 106919, 2024 Jul 04.
Article in English | MEDLINE | ID: mdl-38968759

ABSTRACT

BACKGROUND: The increase in online enticement has led to law enforcement agencies engaging in more proactive policing through undercover chat sting operations. OBJECTIVE: We aimed to identify the topics and communication strategies triggering suspicion in chats between law enforcement officers and offenders and why those topics do not result in suspicion in victim-offender conversations. METHODS: We conducted a thematic analysis identifying: (1) how LEOs trigger suspicion, (2) how offenders communicate suspicion, (3) how LEOs attempt recovery from suspicion, and (4) how these triggers were present but did not trigger suspicion in victim-offender chats. We examined 20 LEO-offender chats and 20 victim-offender chats from US ICAC task forces. RESULTS: We identified four themes that triggered suspicion: risk assessment by the LEO's persona, LEO avoidance measures, details related to the offense and evidence, and proof of identity of chat participants. Offender responses to triggers revealed three themes: discomfort navigating boundaries and uncertainty, risk identification, and risk mitigation. Themes for the LEO's responses to suspicion included: risk assessment for chatters, issues with technology, appeasement, and negative emotional reactions. Finally, juxtaposing triggers onto minor-offender chats yielded four themes: explicit boundary setting, victim risk assessment, deep relationship forming and disclosures, and technology issues. CONCLUSION: This study has implications for law enforcement agencies seeking to reduce suspicion and risk assessment by offenders during internet sting operations.

2.
J Zhejiang Univ Sci B ; : 1-16, 2024 Jul 09.
Article in English, Chinese | MEDLINE | ID: mdl-38993075

ABSTRACT

Grooming, as an evolutionarily conserved repetitive behavior, is common in various animals, including humans, and serves essential functions including, but not limited to, hygiene maintenance, thermoregulation, de-arousal, stress reduction, and social behaviors. In rodents, grooming involves a patterned and sequenced structure, known as the syntactic chain with four phases that comprise repeated stereotyped movements happening in a cephalocaudal progression style, beginning from the nose to the face, to the head, and finally ending with body licking. The context-dependent occurrence of grooming behavior indicates its adaptive significance. This review briefly summarizes the neural substrates responsible for rodent grooming behavior and explores its relevance in rodent models of neuropsychiatric disorders and neurodegenerative diseases with aberrant grooming phenotypes. We further emphasize the utility of rodent grooming as a reliable measure of repetitive behavior in neuropsychiatric models, holding promise for translational psychiatry. Herein, we mainly focus on rodent self-grooming. Allogrooming (grooming being applied on one animal by its conspecifics via licking or carefully nibbling) and heterogrooming (a form of grooming behavior directing towards another animal, which occurs in other contexts, such as maternal, sexual, aggressive, or social behaviors) are not covered due to space constraints.

3.
Neuroscience ; 2024 Jun 13.
Article in English | MEDLINE | ID: mdl-38876356

ABSTRACT

Highly prevalent in laboratory rodents, 'social' hetero-grooming behavior is translationally relevant to modeling a wide range of neuropsychiatric disorders. Here, we comprehensively evaluated known mouse genes linked to aberrant hetero-grooming phenotype and applied bioinformatics tools to construct a network of their established protein-protein interactions (PPI). We next identified several distinct molecular clusters within this network, including neuronal differentiation, cytoskeletal, WNT-signaling and synapsins-associated pathways. Using additional bioinformatics analyses, we further identified 'central' (hub) proteins within these molecular clusters, likely key for mouse hetero-grooming behavior. Overall, a more comprehensive characterization of intricate molecular pathways linked to aberrant rodent grooming may markedly advance our understanding of underlying cellular mechanisms and related neurological disorders, eventually helping discover novel targets for their pharmacological or gene therapy interventions.

4.
J Child Adolesc Trauma ; 17(2): 197-208, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38938953

ABSTRACT

PURPOSE: Identifying sexual grooming behaviors holds potential to reduce the occurrence of child sexual abuse (CSA) and increase disclosure rates. Given the influential role parents play in CSA prevention and the lack of previous research examining parent-specific sexual grooming recognition abilities, this study examined both generalized adult (i.e., parent and nonparent) and parent special abilities to recognize sexual grooming behaviors as identified in the Sexual Grooming Model (SGM), as well as the relationship between reported confidence in recognition abilities and measured abilities. METHODS: The current study used an experimental vignette design among a sample of 420 parents and 445 nonparents to measure abilities to associate sexual grooming behaviors with CSA. Participants also rated how confident they felt in their abilities to recognize signs of sexual grooming. RESULTS: Parental status did not have a significant impact on sexual grooming recognition abilities. However, the sample as a whole (i.e., parents and nonparents combined) were more likely to recognize sexual grooming when presented with behaviors from all of the SGM's stages or behaviors related to desensitization to touch and sexual content. Participant confidence in their recognition abilities did not predict measured abilities. CONCLUSION: Regardless of parental status, the sample did not strongly associate sexual grooming behaviors with CSA perpetration except when behaviors related to sexual content and physical touch were presented. This suggests heightened associations of more overt sexual grooming behaviors with CSA. The discrepancy found between confidence and recognition abilities calls for targeted educational efforts to increase awareness in types of behaviors that may be indicative of abuse.

5.
Genes (Basel) ; 15(6)2024 Jun 11.
Article in English | MEDLINE | ID: mdl-38927699

ABSTRACT

The grooming behavior of honeybees serves as a crucial auto-protective mechanism against Varroa mite infestations. Compared to Apis mellifera, Apis cerana demonstrates more effective grooming behavior in removing Varroa mites from the bodies of infested bees. However, the underlying mechanisms regulating grooming behavior remain elusive. In this study, we evaluated the efficacy of the auto-grooming behavior between A. cerana and A. mellifera and employed RNA-sequencing technology to identify differentially expressed genes (DEGs) in bee brains with varying degrees of grooming behavior intensity. We observed that A. cerana exhibited a higher frequency of mite removal between day 5 and day 15 compared to A. mellifera, with day-9 bees showing the highest frequency of mite removal in A. cerana. RNA-sequencing results revealed the differential expression of the HTR2A and SLC17A8 genes in A. cerana and the CCKAR and TpnC47D genes in A. mellifera. Subsequent homology analysis identified the HTR2A gene and SLC17A8 gene of A. cerana as homologous to the HTR2A gene and SLC17A7 gene of A. mellifera. These DEGs are annotated in the neuroactive ligand-receptor interaction pathway, the glutamatergic synaptic pathway, and the calcium signaling pathway. Moreover, CCKAR, TpnC47D, HTR2A, and SLC17A7 may be closely related to the auto-grooming behavior of A. mellifera, conferring resistance against Varroa infestation. Our results further explain the relationship between honeybee grooming behavior and brain function at the molecular level and provide a reference basis for further studies of the mechanism of honeybee grooming behavior.


Subject(s)
Brain , Grooming , Transcriptome , Varroidae , Animals , Bees/parasitology , Bees/genetics , Varroidae/genetics , Brain/parasitology , Brain/metabolism , Mite Infestations/genetics , Mite Infestations/veterinary , Mite Infestations/parasitology , Gene Expression Profiling/methods
6.
Eur J Investig Health Psychol Educ ; 14(5): 1311-1324, 2024 May 07.
Article in English | MEDLINE | ID: mdl-38785584

ABSTRACT

Online sexual grooming (a manipulative process in which the perpetrator locates a young person and creates an abusive relationship with the child that involves sexual exploitation) poses significant challenges to parents. This study examined how parents of adolescent victims of online sexual grooming experienced guiding their children through the event. This qualitative study, conducted in Israel, was based on semi-structured in-depth interviews with 15 parents who guided their adolescents who had been subjected to online sexual grooming. Results indicate that the parents reported a spectrum of emotions, from insecurity and guilt to a sense of control and satisfaction in managing the situation. Also, the reluctance of some parents to engage with the education system indicates potential trust issues. The study demonstrates the urgent need for targeted interventions to equip parents and educational professionals with the necessary knowledge for prevention and effective response to online sexual grooming. Implications for future research, policy, and practice are discussed.

7.
Sci Rep ; 14(1): 11697, 2024 05 22.
Article in English | MEDLINE | ID: mdl-38777816

ABSTRACT

Allogrooming is a widespread, pervasive activity among non-human primates. Besides its hygienic function, it is thought to be instrumental in maintaining social bonds and establishing hierarchical structures within groups. However, the question arises as to whether the physiological and social benefits derived from social touch stem directly from body stimulation, or whether other mechanisms come into play. We address this question by analyzing an elaborate social behavior that we observed in two adult male macaques. This behavior demonstrates the existence of a persistent motivation to interact through a form of simulated grooming, as the animals were housed in adjacent enclosures separated by a glass panel preventing direct tactile contact. We find that such virtual grooming produces similar physiological sensations and social effects as allogrooming. We suggest that this behavior engages affective and reward brain circuits to the same extent as real social touch, and that this is probably achieved through high level processes similar to those involved in bodily illusions or synaesthetic phenomena previously described in humans. This observation reveals the unsuspected capacity of non-human primates to invent alternative, quasi-symbolic strategies to obtain effects similar to those provided by direct bodily interaction, which are so important for maintaining social bonds.


Subject(s)
Grooming , Social Behavior , Animals , Male , Grooming/physiology , Behavior, Animal/physiology , Touch/physiology , Macaca , Psychophysiology
8.
J Insect Sci ; 24(3)2024 May 01.
Article in English | MEDLINE | ID: mdl-38805645

ABSTRACT

Honey bees use grooming to defend against the devastating parasite Varroa destructor Anderson and Trueman. We observed the grooming responses of individual bees from colonies previously chosen for high- and low-grooming behavior using a combination of mite mortality and mite damage. Our aim was to gain insight into specific aspects of grooming behavior to compare if high-grooming bees could discriminate between a standardized stimulus (chalk dust) and a stimulus of live Varroa mites and if bees from high-grooming colonies had greater sensitivity across different body regions than bees from low-grooming colonies. We hypothesized that individuals from high-grooming colonies would be more sensitive to both stimuli than bees from low-grooming colonies across different body regions and that bees would have a greater response to Varroa than a standardized irritant (chalk dust). Individuals from high-grooming colonies responded with longer bouts of intense grooming when either stimulus was applied to the head or thorax, compared to sham-stimulated controls, while bees from low-grooming colonies showed no differences between stimulated and sham-stimulated bees. Further, high-grooming bees from colonies with high mite damage exhibited greater grooming to Varroa than high-grooming colonies with only moderate mite damage rates. This study provides new insights into Varroa-specific aspects of grooming, showing that although a standardized stimulus (chalk dust) may be used to assess general grooming ability in individual bee grooming assays, it does not capture the same range of responses as a stimulus of Varroa. Thus, continuing to use Varroa mites in grooming assays should help select colonies with more precise sensitivity to Varroa.


Subject(s)
Grooming , Varroidae , Animals , Bees/parasitology , Bees/physiology , Varroidae/physiology
9.
Animals (Basel) ; 14(9)2024 Apr 23.
Article in English | MEDLINE | ID: mdl-38731268

ABSTRACT

In 1992, an evolutionary model for the endogenous regulation of parasite-defense grooming was first proposed for African antelope by Ben and Lynette Hart. Known as the programmed grooming model, it hypothesized that a central control mechanism periodically evokes grooming so as to remove ectoparasites before they blood feed. The programmed grooming model contrasts with a stimulus-driven mechanism, in which grooming is stimulated by direct peripheral irritation from ectoparasite bites. In the 30+ years since the seminal 1992 paper, 26 studies have provided robust support for the programmed grooming model in ungulate hosts and ticks. In addition, multiple studies from unaffiliated investigators have evaluated the predictions of the model in different host systems (including rodents and primates) and in a variety of other ectoparasites (fleas, lice, and keds). I conducted a tricennial review of these studies to assess the current evidence and arrived at the following three conclusions: (1) tests of the programmed grooming predictions should use a similar methodology to the well-established protocol, so that the results are comparable and can be properly assessed; (2) the predictions used to test the model should be tailored to the biology of the host taxa under investigation; and (3) the predictions should likewise be tailored to the biology of the ectoparasites involved, bearing in mind that grooming has varying degrees of effectiveness, depending on the parasite. Further research is warranted to enhance our understanding of the role of grooming in maintaining the health of wild animals in the face of parasite attacks.

10.
Curr Biol ; 34(10): 2066-2076.e3, 2024 05 20.
Article in English | MEDLINE | ID: mdl-38657610

ABSTRACT

Flies groom in response to competing mechanosensory cues in an anterior-to-posterior order using specific legs. From behavior screens, we identified a pair of cholinergic command-like neurons, Mago-no-Te (MGT), whose optogenetic activation elicits thoracic grooming by the back legs. Thoracic grooming is typically composed of body sweeps and leg rubs in alternation, but clonal analysis coupled with amputation experiments revealed that MGT activation only commands the body sweeps: initiation of leg rubbing requires contact between the leg and thorax. With new electron microscopy (EM) connectome data for the ventral nerve cord (VNC), we uncovered a circuit-based explanation for why stimulation of posterior thoracic mechanosensory bristles initiates cleaning by the back legs. Our previous work showed that flies weigh mechanosensory inputs across the body to select which part to groom, but we did not know why the thorax was always cleaned last. Here, the connectome for the VNC enabled us to identify a pair of GABAergic inhibitory neurons, UMGT1, that receives diverse sensory inputs and synapses onto both MGT and components of its downstream circuits. Optogenetic activation of UMGT1 suppresses thoracic cleaning, representing a mechanism by which mechanosensory stimuli on other body parts could take precedence in the grooming hierarchy. We also anatomically mapped the pre-motor circuit downstream of MGT, including inhibitory feedback connections that may enable rhythmicity and coordination of limb movement during thoracic grooming. The combination of behavioral screens and connectome analysis allowed us to identify a neural circuit connecting sensory-to-motor neurons that contributes to thoracic grooming.


Subject(s)
Drosophila melanogaster , Grooming , Animals , Grooming/physiology , Drosophila melanogaster/physiology , Extremities/physiology , Connectome , Optogenetics , Mechanoreceptors/physiology , Mechanotransduction, Cellular
11.
Front Digit Health ; 6: 1325385, 2024.
Article in English | MEDLINE | ID: mdl-38572144

ABSTRACT

Introduction: Online child sexual abuse (OCSA) affects considerable numbers of children globally and is associated with a variety of mental health problems. Existing practitioner studies suggest that young people are infrequently asked about online abuse and practitioners have a fragmented understanding of the problems experienced or how they might approach them. There are very few evidence-based interventions that guide clinical assessment or practice. Digital Health Interventions (DHIs) have the potential to be an effective option where children and young people's services are challenged, including accessibility and anonymity. The aim of this study was to explore mental health practitioners' views of how DHIs may play a role in supporting young people who have experienced OCSA, and the role they can play in healthcare delivery. Method: In-depth qualitative interviews and one focus group were conducted with 25 child mental health professionals across two sites (Manchester and Edinburgh). Data was analyzed using reflexive thematic analysis. Results: Three overarching themes and 9 sub-themes were identified: (1) feeling a little bit lost; (2) seeing potential problems; and (3) knowing what works. Practitioners expressed interest in a DHI to support this client group and saw it as a way of managing waiting lists and complementing existing therapies. They felt that many young people would see this as a preferred medium to in-person therapy, would be empowering, and offers new ways of learning how to stay safe online. However, there were concerns about how much time would be needed by staff to deliver a DHI, anxieties about safety issues in relation to content and data protection, some of which may be unique to this population of young people, and concerns about the absence of a therapeutic relationship with vulnerable children. Discussion: Our findings indicated that practitioners were uncertain about working with children subjected to OCSA but were receptive to the possibility of using a DHI to support their practice and to reduce waiting lists. Concerns were expressed about the time needed for staff training and support as well as concerns over patient safety and the lack of evidence about the effectiveness of an unsupported DHI.

12.
Behav Brain Sci ; : 1-80, 2024 Apr 30.
Article in English | MEDLINE | ID: mdl-38684647

ABSTRACT

Group-living creates stresses that, all else equal, naturally lead to group fragmentation, and hence loss of the benefits that group-living provides. How species that live in large stable groups counteract these forces is not well understood. I use comparative data on grooming networks and cognitive abilities in primates to show that living in large, stable groups has involved a series of structural solutions designed to create chains of 'friendship' (friends-of-friends effects), increased investment in bonding behaviours (made possible by dietary adjustments) to ensure that coalitions work effectively, and neuronally expensive cognitive skills of the kind known to underpin social relationships in humans. The first ensures that individuals synchronise their activity cycles; the second allows the stresses created by group-living to be defused; and the third allows a large number of weak ties to be managed. Between them, these create a form of multilevel sociality based on strong versus weak ties similar to that found in human social networks. In primates, these strategies appear successively at quite specific group sizes, suggesting that they are solutions to 'glass ceilings' that would otherwise limit the range of group sizes that animals can live in (and hence the habitats they can occupy). This sequence maps closely onto the grades now known to underpin the Social Brain Hypothesis and the fractal pattern that is known to optimise information flow round networks.

13.
Elife ; 122024 Apr 18.
Article in English | MEDLINE | ID: mdl-38634460

ABSTRACT

Mechanosensory neurons located across the body surface respond to tactile stimuli and elicit diverse behavioral responses, from relatively simple stimulus location-aimed movements to complex movement sequences. How mechanosensory neurons and their postsynaptic circuits influence such diverse behaviors remains unclear. We previously discovered that Drosophila perform a body location-prioritized grooming sequence when mechanosensory neurons at different locations on the head and body are simultaneously stimulated by dust (Hampel et al., 2017; Seeds et al., 2014). Here, we identify nearly all mechanosensory neurons on the Drosophila head that individually elicit aimed grooming of specific head locations, while collectively eliciting a whole head grooming sequence. Different tracing methods were used to reconstruct the projections of these neurons from different locations on the head to their distinct arborizations in the brain. This provides the first synaptic resolution somatotopic map of a head, and defines the parallel-projecting mechanosensory pathways that elicit head grooming.


Subject(s)
Drosophila , Neurons , Animals , Grooming/physiology , Afferent Pathways , Neurons/physiology , Brain , Drosophila melanogaster/physiology
14.
Behav Genet ; 54(3): 290-301, 2024 May.
Article in English | MEDLINE | ID: mdl-38536593

ABSTRACT

Head grooming in Drosophila consists of repeated sweeps of the legs across the head, comprising regular cycles. We used the GAL4-UAS system to study the effects of overexpressing shibirets1 and of Adar knockdown via RNA interference, on the period of head-grooming cycles in Drosophila. Overexpressing shibirets1 interferes with synaptic vesicle recycling and thus with cell communication, while Adar knockdown reduces RNA editing of neuronal transcripts for a large number of genes. All transgenic flies and their controls were tested at 22° to avoid temperature effects; in wild type, cycle frequency varied with temperature with a Q10 of 1.3. Two experiments were performed with transgenic shibirets1: (1) each fly was heat-shocked for 10 min at 30° immediately before testing at 22° and (2) flies were not heat shocked. In both experiments, cycle period was increased when shibirets1 was overexpressed in all neurons, but was not increased when shibirets1 was overexpressed in motoneurons alone. We hypothesize that grooming cycles in flies overexpressing shibirets1 are lengthened because of synaptic impairment in neural circuits that control head-grooming cycles. In flies with constitutive, pan-neuronal Adar knockdown, cycle period was more variable within individuals, but mean cycle period was not significantly altered. We conclude that RNA editing is essential for the maintenance of within-individual stereotypy of head-grooming cycles.


Subject(s)
Drosophila Proteins , Drosophila , Humans , Animals , Drosophila Proteins/metabolism , Dynamins/genetics , Dynamins/metabolism , Grooming , Neurons/metabolism , Drosophila melanogaster/genetics
15.
BMC Womens Health ; 24(1): 171, 2024 Mar 11.
Article in English | MEDLINE | ID: mdl-38468306

ABSTRACT

BACKGROUND: Pubic hair grooming involves the partial or complete removal of pubic hair, and it is a common practice among men and women. Grooming is more prevalent in women, who employ various methods such as shaving, waxing and laser removal. However, it is associated with variable rates of post-grooming adverse outcomes including lacerations and sexually transmitted infections (STIs). To the best of our knowledge, this is the first systematic review and meta-analysis comparing women's sexual health outcomes between those who groom and those who don't. METHODS: We followed the MOOSE guidelines and conducted a computerized-based search using (PubMed, Web of Science, Scopus, and Ovid Medline), till June 20th, 2022, for eligible studies using the relevant keywords; (pubic hair grooming) OR (pubic hair removal OR Genital hairless OR Bikini hair removal OR pubic hair depilation). Cross-sectional studies included which compared grooming practices among women in terms of motivation and health outcomes. Women's satisfaction and incidence of STIs were pooled as standardized mean difference (SMD) and odds ratio (OR) respectively. RESULTS: Twenty-Two cross-sectional studies were included in our review with 73,091 participant.The odds of having gram-negative gonorrheal and chlamydial infection in Pubic hair groomers were found to be statistically significant (OR = 1.55, 95% CI [1.31, 1.84], P < 0.001) (OR = 1.56, 95% CI [1.32, 1.85], P < 0.001] respectively. There was no difference between groomer and non-groomer women regarding viral infections such as genital herpes (OR = 1.40, 95% CI [0.56, 3.50], P = 0.47) and Condyloma acuminata (OR = 1.75, 95% CI [0.51, 6.01], P = 0.37). The most common grooming side effect is genital itching (prevalence = 26.9%, P < 0.001). Non-electrical razor (prevalence = 69.3%, P < 0.001) is the most common grooming method. White women (prevalence = 80.2%, P < 0.001) remove pubic hair more frequently compared to black women (prevalence = 12.2%, P < 0.001). Women practice complete grooming (50.3%, P < 0.001) of the pubic hair more frequently than partial grooming (33.1%, P < 0.001). There are no differences in women's satisfaction between the two groups (SMD = 0.12, 95% CI [-0.16, 0.40], P = 0.39). CONCLUSION: This review aligns with previous observational studies regarding sexual health outcomes of pubic hair grooming. There is a need to raise awareness among women regarding the safe practice of pubic hair grooming, emphasizing the clarification of hazards and benefits.


Subject(s)
Hair Removal , Sexual Health , Sexually Transmitted Diseases , Male , Animals , Humans , Female , Cross-Sectional Studies , Grooming , Hair Removal/adverse effects , Hair , Sexually Transmitted Diseases/epidemiology
16.
J Interpers Violence ; : 8862605241239450, 2024 Mar 17.
Article in English | MEDLINE | ID: mdl-38494788

ABSTRACT

Individuals who sexually offend often engage in manipulative and coercive behavior to begin, conceal, and continue the sexual abuse of children over time, referred to as grooming behavior. The large majority of research regarding grooming behavior derives exclusively from male sex offending samples, which is problematic because male and female sex offenders vary widely in their offending patterns, motivations, and behaviors. For the present study, we examined the nature of sexual grooming and processes exhibited by a sample of 50 women convicted of sexual offenses against a child. We were guided by Craven et al. model of sexual grooming, which focuses on self, environmental, and child grooming. To date, this is the only proposed model of sexual grooming that includes self-grooming as a step in the grooming process. Data included narrative interviews with women who were arrested, convicted, and assessed for risk and community notification purposes between 2014 and 2019. We also examined interviews with victims, witnesses, and other guardians. The findings from the current study indicated that women who sexually offend utilize a variety of self, environmental, and child grooming behaviors. Self-grooming was an intricate, complex, and layered process that continued throughout the duration of the offense. Details provided by the women in our sample suggested that environmental and child grooming occurred simultaneously rather than two distinct steps. A better understanding of grooming behaviors can assist in the detection of grooming behavior, development of appropriate responses to child victims, and inform future legislation and its implementation. Theoretical and policy implications are discussed.

17.
Behav Brain Res ; 465: 114970, 2024 May 08.
Article in English | MEDLINE | ID: mdl-38531510

ABSTRACT

Alzheimer's disease (AD) patients show age-related decreases in the ability to perform activities of daily living and the decline in these activities is related to the severity of neurobiological deterioration underlying the disease. The 5xFAD mouse model of AD shows age-related impairments in sensory- motor and cognitive function, but little is known about changes in species-typical behaviours that may model activities of daily living in AD patients. Therefore, we examined species-typical behaviours used as indices of exploration (rearing) and compulsivity (grooming) across six tests of anxiety-like behaviour or motor function in female 5xFAD mice from 3 to 16 months of age. Robust decreases in rearing were found in 5xFAD mice across all tests after 9 months of age, although few differences were observed in grooming. A fine-scale analysis of grooming, however, revealed a previously unresolved and spatially restricted pattern of grooming in 5xFAD mice at 13-16 months of age. We then examined changes in species-typical behaviours in the home-cage, and show impaired nest building in 5xFAD mice at all ages tested. Lastly, we examined the relationship between reduced species typical behaviours in 5xFAD mice and the presentation of freezing behaviour, a commonly used measure of memory for conditioned fear. These results showed that along with cognitive and sensory-motor behaviour, 5xFAD mice have robust age-related impairments in species-typical behaviours. Therefore, species typical behaviours in 5xFAD mice may help to model the decline in activities of daily living observed in AD patients, and may provide useful behavioural phenotypes for evaluating the pre-clinical efficacy of novel therapeutics for AD.


Subject(s)
Alzheimer Disease , Mice , Humans , Female , Animals , Infant , Activities of Daily Living , Mice, Transgenic , Cognition , Anxiety , Disease Models, Animal
18.
J Child Sex Abus ; 33(3): 290-319, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38402629

ABSTRACT

Little is known about the extent to which youths who commit harmful sexual behaviors (HSBs) against another minor utilize sexual grooming during the offense process. This study examined sexual grooming behaviors reported by adults (n = 250) who experienced HSBs by another minor during their childhood. Participants completed a self-report survey which included the Sexual Grooming Scale - Victim Version (SGS-V). The results showed that most participants (n = 242; 96.9%) reported at least one sexual grooming behavior, with an average of 11.3 behaviors reported. These findings will be discussed as they pertain to the identification and prevention of HSBs among youth.


Subject(s)
Sexual Behavior , Humans , Male , Female , Adolescent , Sexual Behavior/psychology , Child Abuse, Sexual/psychology , Child , Adult , Young Adult , Adolescent Behavior/psychology
19.
Front Behav Neurosci ; 18: 1340357, 2024.
Article in English | MEDLINE | ID: mdl-38347909

ABSTRACT

Background: As machine learning technology continues to advance and the need for standardized behavioral quantification grows, commercial and open-source automated behavioral analysis tools are gaining prominence in behavioral neuroscience. We present a comparative analysis of three behavioral analysis pipelines-DeepLabCut (DLC) and Simple Behavioral Analysis (SimBA), HomeCageScan (HCS), and manual scoring-in measuring repetitive self-grooming among mice. Methods: Grooming behavior of mice was recorded at baseline and after water spray or restraint treatments. Videos were processed and analyzed in parallel using 3 methods (DLC/SimBA, HCS, and manual scoring), quantifying both total number of grooming bouts and total grooming duration. Results: Both treatment conditions (water spray and restraint) resulted in significant elevation in both total grooming duration and number of grooming bouts. HCS measures of grooming duration were significantly elevated relative to those derived from manual scoring: specifically, HCS tended to overestimate duration at low levels of grooming. DLC/SimBA duration measurements were not significantly different than those derived from manual scoring. However, both SimBA and HCS measures of the number of grooming bouts were significantly different than those derived from manual scoring; the magnitude and direction of the difference depended on treatment condition. Conclusion: DLC/SimBA provides a high-throughput pipeline for quantifying grooming duration that correlates well with manual scoring. However, grooming bout data derived from both DLC/SimBA and HCS did not reliably estimate measures obtained via manual scoring.

20.
Child Abuse Negl ; 149: 106696, 2024 03.
Article in English | MEDLINE | ID: mdl-38359776

ABSTRACT

BACKGROUND: Differences exist between contact and noncontact-driven online child sexual abuse offenders; however, there is still a notable lack of empirical studies with police samples from non-English speaking countries, including Spain. OBJECTIVE: We address this gap by analyzing the criminological characteristics of online child sexual grooming (OCSG) suspected offenders from de-identified law enforcement investigations in Spain. PARTICIPANTS AND SETTING: We anonymously coded data provided by Spanish law enforcement agencies from 257 OCSG cases (i.e., unique chat logs between a suspect and minor) extracted from 98 police reports with index investigation years from 2008 to 2021. A total of 101,391 messages were analyzed. METHODS: Three distinct datasets were created: 257 OCSG cases, 120 unique suspects (79 online-focused, 41 contact-driven), and 234 unique victims. Each dataset focused on different criminological variables for analysis, such as grooming strategy, motivation, and victim high-risk behaviors. RESULTS: There were no significant differences between suspects on gender, age, or criminal offense history. Contact-driven suspects were more likely to use positive rapport (ɸ = 0.18), send unprompted sexually explicit images of themselves (ɸ = 0.19), and offer something in exchange (ɸ = 0.25). Victims of contact-driven individuals were more likely to be male (ɸ = 0.52) and offer something in exchange for sex or sexually explicit images (ɸ = 0.18). Victims of online-focused individuals were more likely to be younger (r = 0.26). CONCLUSIONS: These findings suggest criminological differences in the online grooming strategies between contact-driven and online-focused suspected offenders in Spain.


Subject(s)
Child Abuse, Sexual , Criminals , Child , Animals , Humans , Male , Female , Police , Grooming , Sexual Behavior , Interpersonal Relations
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