Effect of knee joint weight change on knee function recovery and gait after total knee arthroplasty.

BACKGROUND: Knee osteoarthritis (KOA) is a common disease based on degenerative pathological changes. Total knee arthroplasty (TKA) is an effective treatment for end-stage of KOA. However, only volume adaptation can be achieved with current knee prostheses, and it is difficult to achieve weight adaptation. This study focused on the weight difference of knee joints and initially explored the impact of this change on knee joint functional recovery and gait changes in patients after surgery. METHODS: From October 2015 to June 2019, patients who underwent primary unilateral TKA were enrolled in this prospective cohort study with the same brand of knee prostheses. General data were collected from patients who met the criteria. The resected bone and soft tissues were collected and weighed precisely during TKA, and multivariate regression analysis was used to determine the factors affecting the weight of the removed knee tissues. We compared the weight of excised tissues and the total weight of the knee prosthesis, and the weight difference was defined as the increased weight of the knee joint (IWKJ). All patients were evaluated by HSS score, gait analysis, and affected side knee X-ray at two weeks, three months, and the last follow-up after the operation. To further determine the influence of IWKJ on postoperative functional recovery, the relationship between IWKJ, HSS score, and gait analysis was analyzed by univariate regression. RESULTS: In total, 210 patients were eventually included in observation. All patients underwent postoperative follow-up for no less than two years. Multiple regression analysis showed that the course of the disease, body weight, and kellgren-Larencen stage(K-L stage)of the affected knee joint were independent factors affecting the weight of the removed knee tissues and were positively correlated with it. Univariate analysis showed that IWKJ was negatively correlated with HSS score at two weeks and three months after the operation. In addition, the values of spatiotemporal parameters and knee rotation ROM were negatively correlated with IWKJ two weeks after surgery, while outside food load response was positively correlated with IWKJ. Cadence, knee rotation ROM, and Ankle rotation ROM were negatively correlated with IWKJ, while outside food was positively correlated with IWKJ three months after surgery. At the last follow-up, only the hip rotation ROM was positively correlated with IWKJ. CONCLUSIONS: All Patients underwent TKA had varying degrees of increased knee weight. The increased weight was 298.98 ± 63.77 g. Patients' body weight, K-L staging, and disease duration are important factors that cause differences in resected knee tissue. Three months after the operation, the changes in knee joint weight had a negative correlation with the HSS score, which at the same time, it had varying degrees of linearity with gait parameters. However, the influence of weight diminished over time.

Comparisonof early joint amnesia degree after posterior cruciate-retaining and posterior stabilized total knee arthroplasty / 中国组织工程研究

BACKGROUND: Clinical long-term follow-up showed that there is no obvious difference in knee range of motion, 10-15 year prosthesis survival rate, and main clinical manifestations after replacement of posterior cruciate-retaining and posterior stabilized prostheses. However, the debate over the superiority and inferiority of the two knee prostheses remains. OBJECTIVE: To compare the differences of early functional recovery of patients with unilateral knee osteoarthritis after posterior cruciate-retaining and posterior stabilized prosthesis replacement. METHODS: A total of 60 patients with knee osteoarthritis admitted to the First Affiliated Hospital of Anhui Medical University from July 2018 to September 2019 were selected, including 13 males and 47 females, aged 46-83 years old. Of them, 30 patients received posterior cruciate-retaining prosthesis replacement, and 30 patients received posterior stabilized prosthesis replacement. At 3 months after operation and at the last follow-up, joint amnesia score, knee function HSS score, visual analogue scale score, and knee motion range were assessed. The study was approved by the Ethics Committee of the First Affiliated Hospital of Anhui Medical University. RESULTS AND CONCLUSION: (1) Sixty patients were followed up for 5-16 months, and no complications such as periprosthetic infection, loosening, dislocation, or stiffness occurred during the follow-up. (2) At 3 months after surgery and at the last follow-up, joint amnesia score, HSS scores, visual analogue scores, and knee motion range were not significantly different between the two groups (P > 0.05). (3) The results showed that joint amnesia score was not significantly different in early stage after the posterior cruciate-retaining and posterior stabilized prosthesis replacement for unilateral knee osthoarthritis.

The therapeutic effect between metal augment and impacted bone grafting in the hip revision of acetabular bone defect / 医学研究生学报

Objective The application of metal augments in the revision of total hip arthroplasty(THA)has achieved re-markable results in the treatment of bone defects.However,there are limited studies compared this effective method with the traditional treatment.The purpose of this article is to investigate the curative effect of both metal augmentation and impacted bone grafting in the revision of acetabular bone defect. Methods We retrospectively analyzed 20 patients(20 hips)with bone defects after THA in Au-thority of Nanjing General Hospital of Nanjing Military Region from August 2010 to February 2017.These 20 patients were allocated into 2 groups:impacted bone grafting group(n=11,filling acetabular bone defect with autogenous iliac bone and artificial bone)and metal aug-mentation group(n=9,filling acetabular bone defect with metal aug-ment).The duration of surgery,blood loss and the hospital for special surgery knee score(HSS)were compared between these two groups and the Harris score was applied to evaluate the hip function and full weight bearing. Results The surgery duration and blood loss of impacted bone grafting group were significantly increased when compared with the metal augmentation group(44.5±7.82 min vs 36.22±5.19 min and 431.82±57.76 mL vs 333.33±72.80 mL respec-tively).there were 3 cases showed mild bone resorption in the I regions in the impacted bone grafting group, while only one case showed mild bone resorption in the II region in the metal augmentation group.The HSS scores in the metal augmentation group were higher than those in the impacted bone grafting group at the time of postoperative 2 weeks(43.89±2.76 vs 40.82±4.42), 3 months (49.89±2.03 vs 45.27±3.90)and 6 months(53.44±2.46 vs 50.55±3.67), the differences were statistically significant(P<0.001). The Harris scores in the metal augmentation group were higher than those in the impacted bone grafting group(P<0.01).The metal augmentation group had a shorter time of getting out of bed compared with the impacted bone grafting group(P<0.01). Conclusion For those patients with upper acetabular bone defect,revision surgery using metal augments can save the operation time.Meanwhile, it is also superior to the impacted bone grafting in the early prosthesis stability and bone ingrowth,and thus enables to shorten the time on getting out of bed and promote functional.

Comparison of long-term clinical outcomes after bilateral mobile-bearing total knee arthroplasties using PCL-retaining and PCL-substituting implants in the same patients.

PURPOSE: Whether the posterior cruciate ligament (PCL) should be retained or substituted in total knee arthroplasty (TKA) remains an issue of concern. The purpose of this study was to perform within-patient comparisons of mid- and long-term clinical outcomes after mobile-bearing TKA using PCL-retaining (PCLR) and PCL-substituting (PCLS) implant designs. METHODS: Clinical outcomes were assessed in thirty-eight patients (76 knees) who underwent bilateral scheduled staged TKA with a PCLR design on one side and a PCLS design on the other. Median follow-up periods were 118 months (range 60-211) and 114 months (62-198) in knees with PCLR and PCLS implants, respectively. The preoperative diagnosis for all patients was osteoarthritis. The postoperative clinical results of mobile-bearing TKAs using PCLR and PCLS implant designs were evaluated. RESULTS: The postoperative Hospital for Special Surgery and the new Knee Society Knee Scoring System scores revealed no differences between PCLR and PCLS implant designs. Postoperative flexion and extension also did not differ between designs. Postoperative median femorotibial alignment was 4° for PCLR and 5° for PCLS implants, respectively; this difference was not significant. Six of the knees with PCLR and three of the knees with PCLS implants had radiolucent lines around the tibial prostheses; these were less than 1 mm and nonprogressive. CONCLUSIONS: Clinically good results were obtained at approximately 10 years after mobile-bearing TKA using both PCLR and PCLS implant designs bilaterally in the same patients. These results provide conclusive evidence that equivalent clinical results can be obtained with either implant design. LEVEL OF EVIDENCE: Therapeutic study, Level II.

Effect of fast track surgery on functional recovery of knee joint replacement / 中国实用护理杂志

Objective To study the effect of fast tract surgery (FTS) used in patients undergoing total knee arthroplasty (TKA). Methods For the experimental group, 341 inpatients with TKA in the Joint Surgery Department of Shandong Provincial Hospital from June 2014 to June 2015 were treated with FTS nursing measures. For the control group, 355 inpatients with TKA of the same department from January 2013 to May 2014 were treated with conventional nursing measures. The effects of FTS nursing measures, the parameters of patients′ postoperative complications, average hospitalization days and the function recovery of knee joint were evaluated respectively. Results After implementing the FTS nursing measures , the incidence of deep venous thrombosis of lower limbs reduced from 8.45%(30/355) to 2.35%(8/341) (χ2=2.340, P<0.05). The average hospitalization days treated without/with FTS nursing measures were:unilateral knee (14.49±3.62) days (without FTS) vs. (11.95±4.53) days (with FTS), bilateral knees (15.80± 3.01) days (without FTS) vs. (13.19±4.08) days (with FTS)(t=3.166, P<0.05). Two weeks after surgery, the HSS scores in the experimental group was 65.72 ± 5.54, while the HSS scores in the control group was 52.43 ± 7.32 (t=2.452, P < 0.05). Three months after surgery, the HSS scores in the experimental group was 88.72 ± 7.10, while the HSS scores in the control group was 72.14 ± 8.73 (t=2.528, P < 0.05). Conclusions FTS nursing measures could significantly reduce the incidence of deep venous thrombosis of lower limbs, shorten the hospitalization days of inpatients, and promote the functional recovery of knees.