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Rev. Saúde Pública Paraná (Online) ; 2(2): 39-48, 10 dezembro de 2019.
Article in Portuguese | CONASS, SESA-PR, Coleciona SUS | ID: biblio-1128554

ABSTRACT

O objetivo do trabalho foi avaliar fatores sociodemográficos e laboratoriais dos pacientes infectados pelo HIV em uso de terapia antirretroviral (TARV) associados ao Índice de Desenvolvimento Humano Municipal (IDHM). O estudo envolveu 4.900 pacientes de 116 municípios do Paraná, atendidos no período de 2012 a 2015. Os pacientes foram divididos em três grupos de acordo com o tamanho e o IDHM do município de residência. Cidades de pequeno porte/IDHM médio apresentaram taxas mais elevadas de mulheres, indivíduos mais jovens e baixa escolaridade, quando comparadas com as cidades de grande porte/IDHM alto. As taxas totais de resposta imunológica, virológica e completa à TARV foram de 71,9%, 68,2% e 57,1%, respectivamente, com melhores resultados para o grupo vivendo em municípios de grande porte/IDHM alto. Apesar dessas diferenças, as respostas imunológica e virológica foram semelhantes entre os grupos, sugerindo que o grau de desenvolvimento do município não está associado com a efetividade da terapia para o HIV-1. (AU)


The objective of the study was to evaluate sociodemographic and laboratory factors of HIV patients on use of antiretroviral therapy (cART) associated with the Municipal Human Development Index (IDHM). The study enrolled 4,900 HIV-patients from 116 municipalities in the state of Paraná, in the South of Brazil, attended from 2012 to 2015. Patients were divided into three groups according to the size and the IDHM of the city of origin. Small sized/medium-IDHM cities showed higher rates of women, individuals with low educational level and young age, when compared to large sized/high-IDHM ones. The general rates of immunologic, virologic and complete responses to cART were of 71.9%, 68.2% and 57.1%, respectively, and better results were observed in the group from large size/high-IDHM cities. Despite these differences, immunologic and virologic responses were similar between the groups, demonstrating that the municipality level of development is not associated with the effectiveness of HIV-1 therapy. (AU)


Subject(s)
Humans , Male , Female , Effectiveness , Monitoring, Immunologic , Public Health , HIV-1 , Development Indicators , Antiretroviral Therapy, Highly Active
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