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Objective:To investigate research topics and management methods for hospital pharmacy in order to promote the devel -opment of hospital pharmacy researches .Methods:The basic principles , main research fields , strategies and approaches of topic se-lection in hospital pharmacy , as well as the main points of research management were discussed .Results:The main research fields of hospital pharmacy included experimental studies and soft science researches .The principles of selected topics should follow practicabil-ity, scientificity, innovation, feasibility and effectiveness , and the topics should set off from the thinking path of pharmacy , be for the purpose of translational medicine and be based on the practical problems of clinical drug use .The quality evaluation of generic drugs , druggability research and so on could take advantage of close to clinics of hospital pharmacy , which may be the focus aspects .It is nec-essary to establish a continuous improvement of performance inspection system , improve the construction of echelon personnel and drive mechanism, and strengthen the scientific research cooperation inside and outside the team in hospital pharmacy researches .Conclu-sion:The scientific researches on hospital pharmacy are very important to develop pharmacy , which are worthy of further exploration .
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Objective:To establish the method validation of microbial limit tests for hospital paste preparations, including com-pound salicylic acid paste, zinc oxide paste and compound pine tar paste. Methods:According to the microbial limit test described in China pharmacopoeia 2010 edition, the method validation of count of bacteria, fungi and yeasts and tests for specified microorganisms was established. Results:Medium dilution method could be used in bacteria, fungi and yeasts count and specified microorganisms ex-amination for compound salicylic acid paste and zinc oxide paste. For compound pine tar paste, bacteria, fungi and yeasts count and the pseudomonas aeruginosa examination could use medium dilution method, while the staphylococcus aureus examination should employ membrane filtration method. Conclusion:The methods of microbial limit tests for the three hospital paste preparations are established, which can be used to control the quality of hospital preparations effectively.
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OBJECTIVE:To provide reference for the enhancing of the quality of hospital preparations.METHODS:The disqualified reports on Shanghai hospital preparations published in "Shanghai drug and medical equipment quality bulletin" between 2004 and 2007 were collected to investigate the main quality problems.RESULTS:A total of 105 batches(19 dosage forms were covered)of unqualified preparations were reported in spot checks,of which,74(70.5%)were external preparations,17(16.2%)oral preparations,and 14(13.3%)sterility preparations.The common unqualified items include package amount(34.5%),description(15.4%),content(15.4%),pH value(13.6%),and microbial limit(8.2%).The major quality problems were related to package containers and technology.CONCLUSIONS:It is suggested that the concerned department to tighten control on quality of hospital preparations aimed at the above-mentioned problems.
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OBJECTIVE:To facilitate a sound and orderly development of hospital preparations(HP).METHODS:The suggestion of classified management of HP was come up with based on the characteristics of it.RESULTS & CONCLUSIONS:It is advisable for HP be managed by dividing them into market supplement agents,cipher prescription preparation,dosage form reformation agents,sterilizing agents,diagnostic agents and supplemental agents.And the licence numbers of the first 3 categories should be gained from the provincial Food and Drug Administration,while those of the sterilizing agents,diagnostic agents and supplemental agents from the municipal Food and Drug Administration.
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OBJECTIVE:To explore the relationship between cost and price of hospital preparations.METHODS:In?fluence of improvement in quality standards,production standards and package standards of hospital preparation on its cost structure were analyzed.RESULTS&CONCLUSIONS:The present price assessment for hospital preparations should be improved,the department of commodity prices should establish more reasonable price assessment based on the different costs of different preparations in order to reflect the actual value of hospital preparations.
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OBJECTIVE: To survey the developing trend of hospital preparations in China. METHODS: We collected and analyzed 343 articles about "hospital preparation" published on three Journals during the period 1995 to 1999. RESULTS: Pharmacists not only paid attention to develop preparations of Western medicine but also increased the preparations of Chinese herbs gradually. Among the 343 preparations, those of Western medicine accounted for 53.9% (185kinds), preparations of Chinese herbs accounted for 36. 4% (125 kinds) and preparations of integrated traditional Chincse herbs and Western medicine accounted for 9. 6% (33 kinds). Most preparations were made for use in departments of dermatology, stomatology, obstetrics and gynecology(101, 40, 28 kinds respectively ). At the same time, the old preparations have been improved and many new prepara- tions have been offered to the clinic continually. CONCLUSION: Hospital preparations in China are abundant and are expanding along the orientation of new drug development.
