ABSTRACT
Objective To explore thelevels of uric acid,blood pressure,serum lipid metabolic disorders and the distribution of obesity and metabolic syndrome (MS) among Uygur,Han and Kazak pre-diabetic groups in Xinjiang.Methods A cross-sectional study was conducted on 2053 Uygur residents,2219 Kazak residents and 2656 Han residents aged 30-80,all with prediabectic syndromes.The pre-dialectic patients were divided into three groups for analysis on metabolic features and inter-group comparisons.Results (1)In total,1934 pre-diabetic cases (28.3%) were diagnosed,with the highest prevalence (31.6%) seen in Uygurs and the lowest (25.5%) in Kazaks and medium (27.0%) in Hans.Data from the inter-group comparison showed statistically significant differences (P=0.00).(2) Prevalence of high LDL-C was 80.5%,with hyperuricemia as 30.3% and MS as 58.3%,while the inter-group comparison did not show any statistically significant differences (P>0.05).(3)Prevalence of pre-diabetic when combined with hypertension or earlier-stage hypertension,reached 88.0%,with the highest (96.8%) among Kazak group,85.1% in Uygurs and 83.7% in Han population.Data from the inter-group comparison showed statistically significant difference (x2 =59.959,P=0.00).(4)The overall prevalence of prediabectic,when combined with obesity was 35.4%,with 29.6% in Han,36.8% in Uygur and 41.0% in Kazak groups.Data from the inter-group comparison showed statistically significant difference (x2=19.097,P=0.00).Conclusion According to results from this cross-sectional study regarding the metabolic features of Uygur,Kazak and Han prediabectic groups,differences were seen in the prevalence rates of pre-diabetic among Uygur,Kazak and Han ethnic groups,with the highest seen in Uygurs and the lowest in Kazaks.Hyperlipidemia,hypertension,hyperuricemia,MS and obesity were commonly seen in all the prediabectic groups,with the highest prevalence of hypertension seen in the Kazak group and the highest rate of obesity in Uygur group.