DL-methionine and methionine hidroxi analogue free acid in avian feeding / Utilização da DL-metionina e metionina hidroxi-análoga na alimentação de aves

Methionine is an essential sulfur amino acid and appears as first limiting in poultry nutrition. The sources of this amino acid found in an industrial scale in the market today are: DL- 2-amino-4-methylthio butanoic acid (DLM) and DL-2-hydroxy-4 (methyl) butanoic acid, known as methionine hydroxy analog acid free (MHA-AL). Bio-efficiency values was obtained by testing dose-response using exponential models to explain the animals responses to the sources of methionine. It is not only the composition of the basal diet would influence the efficiency of the use of MHA-AL, but the differences in dietary levels of methionine and the total sulfur amino acids contained in the basal diet. The effects on the performance in diets for broilers and laying hens supplemented with this already healthy amino acid consolidated. This review aimed to discuss the use of DL-methionine (DLM) and methionine hydroxy analog free acid (MHA-AL) as a source of methionine for broilers and layers based on experimental data and technical reported in scientific literature.

A metionina é um aminoácido sulfurado essencial e aparece como primeiro limitante nas rações de aves. As fontes deste aminoácido encontradas no mercado são: o ácido DL-2-amino- 4-metiltio butanóico (DLM) e o ácido DL-2- hidroxi-4 (metilo) butanóico, mais conhecido como metionina hidróxi análoga ácido livre (MHA-AL). Os valores de bioeficácia são obtidos através de ensaios de dose-resposta utilizando modelos exponenciais para explicar as respostas dos animais às fontes de metionina. Não é apenas a composição da dieta basal que influenciaria a eficiência da utilização da MHA-AL, mas as diferenças nos níveis da metionina dietética e o total dos aminoácidos sulfurados contidos na dieta basal. Os efeitos sobre o desempenho em rações para frangos de corte e poedeiras suplementadas com este aminoácido já são consolidados. Objetivou-se com esta revisão discutir a suplementação da DL-Metionina (DLM) e Metionina Hidróxi Análoga acido livre (MHA-AL) como fonte do aminoácido metionina para frangos de corte e poedeiras, sob a ótica acadêmica e da indústria, abordando os aspectos nutricionais, econômicos dentre outros.

DL-methionine and methionine hidroxi analogue free acid in avian feeding / Utilização da DL-metionina e metionina hidroxi-análoga na alimentação de aves

Methionine is an essential sulfur amino acid and appears as first limiting in poultry nutrition. The sources of this amino acid found in an industrial scale in the market today are: DL- 2-amino-4-methylthio butanoic acid (DLM) and DL-2-hydroxy-4 (methyl) butanoic acid, known as methionine hydroxy analog acid free (MHA-AL). Bio-efficiency values was obtained by testing dose-response using exponential models to explain the animals responses to the sources of methionine. It is not only the composition of the basal diet would influence the efficiency of the use of MHA-AL, but the differences in dietary levels of methionine and the total sulfur amino acids contained in the basal diet. The effects on the performance in diets for broilers and laying hens supplemented with this already healthy amino acid consolidated. This review aimed to discuss the use of DL-methionine (DLM) and methionine hydroxy analog free acid (MHA-AL) as a source of methionine for broilers and layers based on experimental data and technical reported in scientific literature.

A metionina é um aminoácido sulfurado essencial e aparece como primeiro limitante nas rações de aves. As fontes deste aminoácido encontradas no mercado são: o ácido DL-2-amino- 4-metiltio butanóico (DLM) e o ácido DL-2- hidroxi-4 (metilo) butanóico, mais conhecido como metionina hidróxi análoga ácido livre (MHA-AL). Os valores de bioeficácia são obtidos através de ensaios de dose-resposta utilizando modelos exponenciais para explicar as respostas dos animais às fontes de metionina. Não é apenas a composição da dieta basal que influenciaria a eficiência da utilização da MHA-AL, mas as diferenças nos níveis da metionina dietética e o total dos aminoácidos sulfurados contidos na dieta basal. Os efeitos sobre o desempenho em rações para frangos de corte e poedeiras suplementadas com este aminoácido já são consolidados. Objetivou-se com esta revisão discutir a suplementação da DL-Metionina (DLM) e Metionina Hidróxi Análoga acido livre (MHA-AL) como fonte do aminoácido metionina para frangos de corte e poedeiras, sob a ótica acadêmica e da indústria, abordando os aspectos nutricionais, econômicos dentre outros.

Methionine sources do not affect performance and carcass yield of broilers fed vegetable diets and aubmitted to cyclic heat stress

The supplementation of vegetal diets with L-methionine (100% molar), methionine hydroxyl analogue (HMB) (88% molar) or DL-methionine (99% molar) was compared as to the performance of broilers allocated in cages and submitted to cyclic heat stress (CHS). The trial was carried out from 21 to 42 days of age. Two levels of synthetic methionine were supplemented for each methionine source (0.1 or 0.3 %), and the control treatment was not supplemented with synthetic methionine (negative control). Statistical analyses included the negative control treatment or were performed in a 3 x 2 factorial design (sources x levels). Addition of synthetic methionine to the basal level containing 0.63 % of total sulphur amino acids significantly improved feed conversion (FC) independent of the source. On the other hand, improvements in weight gain (WG) and body weight (BW) were more consistent comparing the negative control to HMB-supplemented treatments. Factorial analysis showed better FC for L-Met compared to DL-Met, whereas HMB showed intermediate results. The supplementation level of 0.3% methionine showed better FC than 0.1%. Methionine levels or sources had no effects on carcass, yields of cuts or feathering results. Therefore, results of DL-Met and HMB added to vegetal-based diets in comparable molar terms promoted similar performance in broilers under CHS conditions.

Methionine sources do not affect performance and carcass yield of broilers fed vegetable diets and aubmitted to cyclic heat stress

The supplementation of vegetal diets with L-methionine (100% molar), methionine hydroxyl analogue (HMB) (88% molar) or DL-methionine (99% molar) was compared as to the performance of broilers allocated in cages and submitted to cyclic heat stress (CHS). The trial was carried out from 21 to 42 days of age. Two levels of synthetic methionine were supplemented for each methionine source (0.1 or 0.3 %), and the control treatment was not supplemented with synthetic methionine (negative control). Statistical analyses included the negative control treatment or were performed in a 3 x 2 factorial design (sources x levels). Addition of synthetic methionine to the basal level containing 0.63 % of total sulphur amino acids significantly improved feed conversion (FC) independent of the source. On the other hand, improvements in weight gain (WG) and body weight (BW) were more consistent comparing the negative control to HMB-supplemented treatments. Factorial analysis showed better FC for L-Met compared to DL-Met, whereas HMB showed intermediate results. The supplementation level of 0.3% methionine showed better FC than 0.1%. Methionine levels or sources had no effects on carcass, yields of cuts or feathering results. Therefore, results of DL-Met and HMB added to vegetal-based diets in comparable molar terms promoted similar performance in broilers under CHS conditions.

Performance of broilers fed with different levels of methionine hydroxy analogue and DL-methionine

One-day-old male Ross chicks were used in an experiment designed to compare two methionine sources, DL-methionine and methionine hydroxy analogue free acid (MHA-FA), and four different levels: 0.41; 0.47; 0.53; 0.59% (starter diet); 0.35; 0.41; 0.47; 0.53% (grower diet); and 0.30; 0.36; 0.42; 0.48% (finisher diet). One thousand two hundred and eighty chicks were housed in 32 experimental floor-pens (40 birds each) and fed 8 experimental diets based on corn and soybean meal for 47 days. The effects of methionine sources and levels were evaluated by performance data, carcass and cut yields, feather yield and abdominal fat content. Data were analyzed as a completely randomized design in a 2x4 factorial arrangement (2 sources and 4 levels), with 8 treatments and 4 repetitions. Analysis of variance was performed using PROC GLM of SAS©. Data indicated DL-methionine to be more effective in promoting growth than MHA-FA, and weight gain increased numerically in response to increasing levels of methionine in all phases.

Performance of broilers fed with different levels of methionine hydroxy analogue and DL-methionine

One-day-old male Ross chicks were used in an experiment designed to compare two methionine sources, DL-methionine and methionine hydroxy analogue free acid (MHA-FA), and four different levels: 0.41; 0.47; 0.53; 0.59% (starter diet); 0.35; 0.41; 0.47; 0.53% (grower diet); and 0.30; 0.36; 0.42; 0.48% (finisher diet). One thousand two hundred and eighty chicks were housed in 32 experimental floor-pens (40 birds each) and fed 8 experimental diets based on corn and soybean meal for 47 days. The effects of methionine sources and levels were evaluated by performance data, carcass and cut yields, feather yield and abdominal fat content. Data were analyzed as a completely randomized design in a 2x4 factorial arrangement (2 sources and 4 levels), with 8 treatments and 4 repetitions. Analysis of variance was performed using PROC GLM of SAS©. Data indicated DL-methionine to be more effective in promoting growth than MHA-FA, and weight gain increased numerically in response to increasing levels of methionine in all phases.