[Disciplinary responsibility of medical workers in medical organizations].

Bringing to disciplinary responsibility of medical workers in the context of reforming the system of personnel training for the medical field, the introduction of digital technologies into the daily activities of a doctor, acquires pronounced specific features. The purpose of the study is to review the current labor legislation regulating labor discipline and identify the grounds for bringing medical workers to disciplinary responsibility in medical organizations.

Addressing researcher fraud: retrospective, real-time, and preventive strategies-including legal points and data management that prevents fraud.

Researcher fraud is often easy and enticing in academic research, with little risk of detection. Cases of extensive fraud continue to occur. The amount of fraud that goes undetected is unknown and may be substantial. Three strategies for addressing researcher fraud are (a) retrospective investigations after allegations of fraud have been made, (b) sting operations that provide conclusive evidence of fraud as it occurs, and (c) data management practices that prevent the occurrence of fraud. Institutional and regulatory efforts to address researcher fraud have focused almost exclusively on the retrospective strategy. The retrospective approach is subject to controversy due to the limitations of post-hoc evidence in science, the difficulty in establishing who actually committed the fraud in some cases, the application of a legal standard of evidence that is much lower than the usual standards of evidence in science, and the lack of legal expertise by scientists investigating fraud. The retrospective strategy may be reliably effective primarily in cases of extensive, careless fraud. Sting operations can overcome these limitations and controversies, but are not feasible in many situations. Data management practices that are effective at preventing researcher fraud and unintentional errors are well-established in clinical trials regulated by government agencies, but appear to be largely unknown or unimplemented in most academic research. Established data management practices include: archiving secure copies of the raw data, audit trails, restricted access to the data and data collection processes, software validation, quality control checks, blinding, preregistration of data processing and analysis programs, and research audits that directly address fraud. Current discussions about data management in academic research focus on sharing data with little attention to practices that prevent intentional and unintentional errors. A designation or badge such as error-controlled data management could be established to indicate research that was conducted with data management practices that effectively address intentional and unintentional errors.

The punishment intensity for research misconduct and its related factors: An exploratory study on hospitals in Mainland China.

Previous studies have found that factors such as gender and academic positions do not influence the severity of administrative actions taken by institutions. However, this study provides partly inconsistent evidence. It focuses on incidents of research misconduct in hospitals across Mainland China and explores factors related to punishment using a large cross-sectional dataset (N = 815). Regression analysis revealed a significant correlation between authorship order and the punishment intensity (p < 0.05). Under specific conditions, there was a significant correlation between the professional title (senior) and punishment intensity (p = 0.001), and an interaction between professional title and types of research misbehavior. Further analysis of simple effects showed that, in cases of fabrication and falsification, and combinations of multiple research misbehavior, researchers with senior titles received significantly lighter punishments compared to those with junior, intermediate, and associate senior titles (p < 0.05). The study unveils the potential accountability patterns (collective accountability and tiered punishment) that may be adopted by hospitals in Mainland China, as well as the challenges faced in ensuring fairness, emphasizing the importance of independent investigative bodies for incidents of research misconduct, and advocating for fairness as a priority in governance of research misconduct.

On "intent" in research misconduct.

Research misconduct, broadly defined as acts of fabrication, falsification and/or plagiarism, violate the value system of science, cost significant wastage of public resources, and in more extreme cases endanger research participants or members of the society at large. Determination of culpability in research misconduct requires establishment of intent on the part of the respondent or perpetrator. However, "intent" is a state of mind, and its perception is subjective, unequivocal evidence for which would not be as readily established compared to the objective evidence available for the acts themselves. Here, we explore the concept of "intent" in research misconduct, how it is framed in criminological/legal terms, and narrated from a psychological perspective. Based on these, we propose a framework whereby lines of questioning and investigation, as defined by legislative terms and informed by the models and tools of psychology, could help in establishing a preponderance of evidence for culpable intent. Such a framework could be useful in research misconduct adjudications and in delivering sanctions.

Identification of retracted publications and completeness of retraction notices in public health.

OBJECTIVES: Retraction is intended to be a mechanism to correct the published body of knowledge when necessary due to fraudulent, fatally flawed, or ethically unacceptable publications. However, the success of this mechanism requires that retracted publications be consistently identified as such and that retraction notices contain sufficient information to understand what is being retracted and why. Our study investigated how clearly and consistently retracted publications in public health are being presented to researchers. STUDY DESIGN AND SETTING: This is a cross-sectional study, using 441 retracted research publications in the field of public health. Records were retrieved for each of these publications from 11 resources, while retraction notices were retrieved from publisher websites and full-text aggregators. The identification of the retracted status of the publication was assessed using criteria from the Committee on Publication Ethics and the National Library of Medicine. The completeness of the associated retraction notices was assessed using criteria from Committee on Publication Ethics and Retraction Watch. RESULTS: Two thousand eight hundred forty-one records for retracted publications were retrieved, of which less than half indicated that the article had been retracted. Less than 5% of publications were identified as retracted through all resources through which they were available. Within single resources, if and how retracted publications were identified varied. Retraction notices were frequently incomplete, with no notices meeting all the criteria. CONCLUSIONS: The observed inconsistencies and incomplete notices pose a threat to the integrity of scientific publishing and highlight the need to better align with existing best practices to ensure more effective and transparent dissemination of information on retractions.

A Study of Attitudes Toward Teacher-Student Sexual Misconduct Cases Based on Student Age, Student Gender, and Teacher Gender.

Teacher-student sexual misconduct is a serious instance of child sexual abuse that impacts an estimated 10% of students. We tested whether two effects seen in research about these types of cases replicated across online American adult and undergraduate samples: (1) sympathy toward younger students who experience sexual abuse compared to older students and (2) leniency in cases of female teachers engaging with male students compared to other gender dyads. Participants (N = 525) reviewed a mock teacher-student sexual encounter and then answered questions about their views and case-related outcomes. Student age emerged as the most influential factor across all our variables of interest, where cases with younger students were viewed as more egregious than those involving older students. Incidents involving boys who experienced abuse were perceived as more "normal" than those involving girls. We found some support for the idea that there is leniency toward women teachers, but limited support for a female teacher-male student leniency effect. While these cases were viewed to be more normal and acceptable than other gender dyads, there were no effects on the other dependent variables. Sample type effects were also minimal, as our adult sample viewed the teachers involved to be more responsible and student complainants as more credible versus the undergraduate sample.

Examining and Comparing the First Public Olympic and Competitive Sports Misconduct Registry with the National Sex Offense Registry.

In 2017, the U.S. Center for SafeSport launched the first public disciplinary sports registry listing individuals accused of engaging in harmful behavior against child and adult athletes. Our study reviews information from 1,161 individuals on SafeSport's sports registry. Of the individuals on the sports registry, 22% were concurrently listed on the national registry for sexual offenses. Relative to individuals listed only on the sports registry, those on both registries were 4.5 and 1.4 times more likely to have sexual misconduct allegations and allegations involving a child, respectively. Of those on both registries, 31% were on the national registry approximately seven years before appearing on the sports registry. We discuss whether and how public registries represent effective strategies for crime prevention.

Retracted papers originating from paper mills: a cross-sectional analysis of references and citations.

OBJECTIVES: The aims of this study are (1) to analyze the references cited by retracted papers originated from paper mills; (2) to analyze the citations received by retracted papers originated from paper mills; and (3) to analyze the potential relationships existing between paper mill papers and their references and their citations. STUDY DESIGN AND SETTING: This study was a cross-sectional study. All original papers retracted in 2022 identified as having originated from paper mills and had been published at least 12 months before their retraction (hereinafter "source-retracted papers") were included. The Retraction Watch database was used to identify the source-retracted papers and Web of Science was used to identify the references contained within them and the citations received by them. We described the characteristics of the papers and journals. Additionally, 2 networks of source-retracted papers mutually interconnected via their citations and references were built: 1 with only retracted references and retracted citations and the other with all references and citations (retracted or unretracted). RESULTS: A total of 416 paper mill papers retracted in 2022 (sourced retracted papers) were identified, with a median of 1247 (interquartilic range, 907.8-1673.5) days between publication and retraction. Of all authors identified, 92.3% were affiliated with Chinese institutions. There were 14,411 references contained in the source-retracted papers and 8479 citations received by them; the median number of references and citations was 35 (29-40) and 16 (9-25), respectively. In total, 473 references and citations had also been retracted for being paper mill papers. Among the 416 sourced-retracted papers, 169 (41.9%) and 178 (42.8%) were referenced or were cited by at least another retracted paper, the majority of which also originated from paper mills. The first network analysis, which included source-retracted papers along with their retracted references and citations, found 3 clusters of 53, 48, and 44 retracted papers that were mutually interconnected. The second network analysis, with all references and citations (retracted or unretracted) identified a large cluster of 2530 interconnected papers. CONCLUSION: Retracted papers originating from paper mills frequently reference and are cited by papers that are later retracted for having originated from paper mills, displaying inter-relationships. Detecting these inter-relationships can serve as an indicator for identifying potentially fraudulent publications.

William Lawrence Tower's Beetles: Experimental Evolution and the Manipulation of Inheritance.

William Lawrence Tower's work on the evolution of the Colorado Potato Beetle (Leptinotarsa decemlineata), documenting the environmental induction of mutation and speciation, made him a leading figure in experimental genetics during the first decade of the 20th century. His research program served as a model for other experimental evolution studies seeking to demonstrate the environmental modification of inheritance. Tower enjoyed the support of influential figures in the field, despite well-known problems that plagued Tower's earlier academic career. The validity of his genetic work, and other findings reported by Tower, were later challenged. The Tower affair illustrates how questionable and possibly fraudulent scientific practices can be tolerated to explore certain experimental directions and theoretical frameworks, particularly at the frontier of expanding disciplines. When needed, those explorations can be forestalled or extinguished by exploiting conspicuous vulnerabilities of rogue practitioners. In Tower's case, both unrefuted allegations of scientific misconduct and personal problems dissolved his institutional support, leading to a swift ouster from academic science. Tower's downfall discredited soft inheritance and neo-Lamarckian conceptions in the field of experimental genetics, facilitating the discipline's embrace of a hard inheritance model that featured a hereditary material resistant to environmental modification.

Publishing important work that lacks validity or reproducibility - pushing frontiers or corrupting science?

Scientific research requires objectivity, impartiality and stringency. However, scholarly literature is littered with preliminary and explorative findings that lack reproducibility or validity. Some low-quality papers with perceived high impact have become publicly notable. The collective effort of fellow researchers who follow these false leads down blind alleys and impasses is a waste of time and resources, and this is particularly damaging for early career researchers. Furthermore, the lay public might also be affected by socioeconomic repercussions associated with the findings. It is arguable that the nature of scientific research is such that its frontiers are moved and shaped by cycles of published claims inducing in turn rounds of validation by others. Using recent example cases of room-temperature superconducting materials research, I argue instead that publication of perceptibly important or spectacular claims that lack reproducibility or validity is epistemically and socially irresponsible. This is even more so if authors refuse to share research materials and raw data for verification by others. Such acts do not advance, but would instead corrupt science, and should be prohibited by consensual governing rules on material and data sharing within the research community, with malpractices appropriately sanctioned.

Concerns about data integrity across 263 papers by one author.

OBJECTIVE: Comprehensive investigation of published work by authors suspected of academic misconduct can reveal further concerns. We aimed to test for data integrity concerns in papers published by an author with eight retracted articles. STUDY DESIGN: We investigated the integrity of all papers reporting on prospective clinical studies by this author. We assessed the feasibility of study methods, baseline characteristics, and outcomes. We plotted the author's clinical research activity over time. We conducted pairwise comparisons of text, tables, and figures to identify duplicate publications, and checked for consistency between conference abstracts, interim analyses, trial registrations, and final papers. Where indicated, we recalculated p-values from the reported summary statistics. RESULTS: We identified 263 papers claiming to have enrolled 74,667 participants between January 2009 and July 2022, 190 (72%) of which reported on studies that recruited from the Assiut Women's Health Hospital in Assiut, Egypt. The number of active studies per month was greatest between 2016 and 2019, with 88 ongoing studies in May 2017. We found evidence of data integrity concerns in 130 (49%) papers, 43 (33%) of which contained concerns sufficient to suggest that they could not be based on data reliably collected from human participants. CONCLUSION: Our investigation finds evidence of widespread integrity concerns in the collected work of one author. We recommend that the involved journals collaborate in a formal investigation.

Sexual Boundary Violations by Doctors - Context, Regulatory Consequences and Preventive Strategies.

While sexual boundary violations by doctors (SBVs) are viewed with utmost seriousness by disciplinary bodies and tribunals, complaints of SBVs in Australia continue to increase. In 2023, the Australian Health Practitioner Regulation Agency (Ahpra) outlined a "blueprint" to protect patients better from sexual misconduct in healthcare: reform being considered in 2024, by Australian health ministers. Few analyses or studies have offered an overview of the prevalence, effects, and causes of SBVs, nor the duties, liabilities, possible disciplinary action against, and potential treatment of, doctors who commit them. This column offers such an overview, and considers, additionally, whether doctors who may have psychiatric disorders associated with their boundary violations would be suitable candidates for treatment. Ultimately, we contend that a purely "responsive" approach is inadequate, and preventive measures such as screening and more effective education should be considered in medical schools as a way of reducing the incidence of SBVs.

Knowledge, Attitude, and Practices About Research Integrity and Scientific Misconduct Among the Faculty and Medical Postgraduates Working in Medical Colleges in North Karnataka and Central India: A Cross-Sectional Online Survey.

Introduction Research integrity is an active adherence to the ethical principles and professional standards essential for the responsible practice of research. Research or scientific misconduct stands like child abuse today. The survey of National Institutes of Health (NIH)-funded scientists calculated an absolute minimum of 2325 incidents of scientific misconduct per year. A report has also shown that Iran (6.60), India (5.68), Turkey (5.38), South Korea (3.59), and China (2.00) had higher ratios of publication misconduct to distrust data or interpretations than other countries. Hence, to determine the knowledge, attitude, and practices (KAPs) of the research integrity/scientific misconduct among the faculty and postgraduates working in the medical colleges in North Karnataka (NK) and Central India (CI), this study has been carried out. Methods It is a web-based, cross-sectional study carried out with the use of Google Forms (Google, Mountain View, California). A pretested, unstructured questionnaire consisting of 25 questions was posted in the way of a link to the faculty and postgraduates working in various disciplines within the colleges of NK and CI either by using an e-mail or other social platforms like WhatsApp. Institutional Ethics Committee approval was obtained in both regions before conducting the survey. Results A total of 146 participants responded to the e-questionnaire posted to them. Participants from CI displayed better awareness in several areas compared to NK. Citing articles and/ or materials that have not been read is the common questionable research practice (QRP) they have come across, as mentioned by participants in both groups. Discussion The study reveals a moderate level of knowledge and variable attitudes toward research integrity. The "publish or perish" culture is a major contributor to misconduct. Training and awareness programs are needed to enhance ethical research practices. Conclusion This study highlights the need for improved education and policy implementation to uphold research integrity in medical colleges, emphasizing the role of academic culture in shaping ethical research practices.

Muller and mutations: mouse study of George Snell (a postdoc of Muller) fails to confirm Muller's fruit fly findings, and Muller fails to cite Snell's findings.

In 1931, Hermann J. Muller's postdoctoral student, George D. Snell (Nobel Prize recipient--1980) initiated research to replicate with mice Muller's X-ray-induced mutational findings with fruit flies. Snell failed to induce the two types of mutations of interest, based on fly data (sex-linked lethals/recessive visible mutations) even though the study was well designed, used large doses of X-rays, and was published in Genetics. These findings were never cited by Muller, and the Snell paper (Snell, Genetics 20:545-567, 1935) did not cite the 1927 Muller paper (Muller, Science 66:84, 1927). This situation raises questions concerning how Snell wrote the paper (e.g., ignoring the significance of not providing support for Muller's findings in a mammal). The question may be raised whether professional pressures were placed upon Snell to downplay the significance of his findings, which could have negatively impacted the career of Muller and the LNT theory. While Muller would receive worldwide attention, and receive the Nobel Prize in 1946 "for the discovery that mutations can be induced by X-rays," Snell's negative mutation data were almost entirely ignored by his contemporary and subsequent radiation genetics/mutation researchers. This raises questions concerning how the apparent lack of interest in Snell's negative findings helped Muller professionally, including his success in using his fruit fly data to influence hereditary and cancer risk assessment and to obtain the Nobel Prize.

Working environment for historically marginalized faculty, administrators, and librarians in pharmacy education.

INTRODUCTION: Promoting diversity among faculty, administrators, and librarians in schools and colleges of pharmacy (SCOP) would be beneficial for the recruitment and retention of students from diverse backgrounds. Graduating such diverse pharmacists could assist in reducing healthcare disparities. Promoting diversity requires a climate that is inclusive of people from all backgrounds. The goal of this study was to examine the working environment of historically marginalized faculty, administrators, and librarians within pharmacy education. METHODS: An electronic survey was administered to all faculty, administrators, and librarians listed in the American Association of Colleges of Pharmacy roster. RESULTS: Responses from 339 participants were analyzed. Twenty-seven percent of these participants either observed or personally experienced misconduct during the previous five years. When action was taken, it resulted in the cessation of the misconduct only 38% of the time. Respondents most frequently identified the following as ways to make it easier to address misconduct: support from supervisors, support from peers, and education on how to address misconduct. CONCLUSIONS: Exclusionary, intimidating, offensive, and/or hostile communication/behaviors towards historically marginalized faculty, administrators, and librarians do exist in SCOP. The academy should work towards promoting diversity, equity, and inclusion in SCOP through education and provide administrative and peer support for reporting and managing professional misconduct.

Insider Threats to the Military Health System: A Systematic Background Check of TRICARE West Providers.

Background: To address the pandemic, the Defense Health Agency (DHA) expanded its TRICARE civilian provider network by 30.1%. In 2022, the DHA Annual Report stated that TRICARE's provider directories were only 80% accurate. Unlike Medicare, the DHA does not publicly reveal National Provider Identification (NPI) numbers. As a result, TRICARE's 9.6 million beneficiaries lack the means to verify their doctor's credentials. Since 2013, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) has excluded 17,706 physicians and other providers from federal health programs due to billing fraud, neglect, drug-related convictions, and other offenses. These providers and their NPIs are included on the OIG's List of Excluded Individuals and Entities (LEIE). Patients who receive care from excluded providers face higher risks of hospitalization and mortality. Objective: We sought to assess the extent to which TRICARE screens health care provider names on their referral website against criminal databases. Methods: Between January 1-31, 2023, we used TRICARE West's provider directory to search for all providers within a 5-mile radius of 798 zip codes (38 per state, ≥10,000 residents each, randomly entered). We then copied and pasted all directory results' first and last names, business names, addresses, phone numbers, fax numbers, degree types, practice specialties, and active or closed statuses into a CSV file. We cross-referenced the search results against US and state databases for medical and criminal misconduct, including the OIG-LEIE and General Services Administration's (GSA) SAM.gov exclusion lists, the HHS Office of Civil Rights Health Insurance Portability and Accountability Act (HIPAA) breach reports, 15 available state Medicaid exclusion lists (state), the International Trade Administration's Consolidated Screening List (CSL), 3 Food and Drug Administration (FDA) debarment lists, the Federal Bureau of Investigation's (FBI) list of January 6 federal defendants, and the OIG-HHS list of fugitives (FUG). Results: Our provider search yielded 111,619 raw results; 54 zip codes contained no data. After removing 72,156 (64.65%) duplicate entries, closed offices, and non-TRICARE West locations, we identified 39,463 active provider names. Within this baseline sample group, there were 2398 (6.08%) total matches against all exclusion and sanction databases, including 2197 on the OIG-LEIE, 2311 on the GSA-SAM.gov list, 2 on the HIPAA list, 54 on the state Medicaid exclusion lists, 69 on the CSL, 3 on the FDA lists, 53 on the FBI list, and 10 on the FUG. Conclusions: TRICARE's civilian provider roster merits further scrutiny by law enforcement. Following the National Institute of Standards and Technology 800, the DHA can mitigate privacy, safety, and security clearance threats by implementing an insider threat management model, robust enforcement of the False Claims Act, and mandatory security risk assessments. These are the views of the author, not the Department of Defense or the US government.

Advancing data honesty in experimental biology.

The ease with which scientific data, particularly certain types of raw data in experimental biology, can be fabricated without trace begs urgent attention. This is thought to be a widespread problem across the academic world, where published results are the major currency, incentivizing publication of (usually positive) results at the cost of lax scientific rigor and even fraudulent data. Although solutions to improve data sharing and methodological transparency are increasingly being implemented, the inability to detect dishonesty within raw data remains an inherent flaw in the way in which we judge research. We therefore propose that one solution would be the development of a non-modifiable raw data format that could be published alongside scientific results; a format that would enable data authentication from the earliest stages of experimental data collection. A further extension of this tool could allow changes to the initial original version to be tracked, so every reviewer and reader could follow the logical footsteps of the author and detect unintentional errors or intentional manipulations of the data. Were such a tool to be developed, we would not advocate its use as a prerequisite for journal submission; rather, we envisage that authors would be given the option to provide such authentication. Only authors who did not manipulate or fabricate their data can provide the original data without risking discovery, so the mere choice to do so already increases their credibility (much like 'honest signaling' in animals). We strongly believe that such a tool would enhance data honesty and encourage more reliable science.

Key concepts in clinical epidemiology: research integrity definitions and challenges.

Research integrity is guided by a set of principles to ensure research reliability and rigor. It serves as a pillar to uphold society's trust in science and foster scientific progress. However, over the past 2 decades, a surge in research integrity concerns, including fraudulent research, reproducibility challenges, and questionable practices, has raised critical questions about the reliability of scientific outputs, particularly in biomedical research. In the biomedical sciences, any breaches in research integrity could potentially lead to a domino effect impacting patient care, medical interventions, and the broader implementation of healthcare policies. Addressing these breaches requires measures such as rigorous research methods, transparent reporting, and changing the research culture. Institutional support through clear guidelines, robust training, and mentorship is crucial to fostering a culture of research integrity. However, structural and institutional factors, including research incentives and recognition systems, play an important role in research behavior. Therefore, promoting research integrity demands a collective effort from all stakeholders to maintain public trust in the scientific community and ensure the reliability of science. Here we discuss some definitions and principles, the implications for biomedical sciences, and propose actionable steps to foster research integrity.