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1.
Pharmaceuticals (Basel) ; 16(11)2023 Oct 30.
Article in English | MEDLINE | ID: mdl-38004398

ABSTRACT

Although medical wound dressings produced using hydrocolloids and alginate were effective in wound healing, adhesion at the wound site and the resulting delayed healing have been a problem. As a new wound dressing material, crystalline wound dressings produced from glucose/mannose were used in this study, which aimed to clarify the properties, adhesion reduction, and wound healing performance of a new wound dressing. Crystalline glucose/mannose films were obtained via alkali treatment using the solution casting method. The structure of the crystalline glucose/mannose films was analogous to the cellulose II polymorph, and the crystallinity decreased with time in hydrated conditions. The crystalline glucose/mannose films had adequate water absorption of 34 × 10-4 g/mm3 for 5 min. These allowed crystalline glucose/mannose films to remove excess wound exudates while maintaining a moist wound healing condition. This in vivo study demonstrated the healing effects of three groups, which were crystalline glucose/mannose group > alginate group > hydrocolloid group. At 1 week, the crystalline glucose/mannose group was also found to be non-adhesive to the portion of wound healing. This was evidenced by the earlier onset of the healing process, which assisted in re-epithelization and promotion of collagen formation and maturation. These results implied that crystalline glucose/mannose films were a promising candidate that could accelerate the wound healing process, compared with medical-grade wound dressing and alginate.

2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-1006255

ABSTRACT

@#Objective To observe the effect of new moist dressings on pressure ulcers after spinal cord injury. Methods 58 spinal cord injured patients complicated with pressure ulcers were divided into observation group (n=29) and control group (n=29). The observation group accepted moist dressings, while the control group accepted routine dry dressings, TDP and ultraviolet irradiation. The incidence of im provement were recorded 2 weeks after treatment, and the time of healing were compared. Results 11 cases cured, 17 cases relieved in the observation group, and it was 5 and 18 cases in the control group, respectively (P<0.05). It spent (26.69±16.48) days to cure in the observa tion group, and (38.24±22.47) days in the control group (P<0.05). Conclusion The moist therapy may promote the cure of pressure ulcers af ter spinal cord injury, and shorten the time of cure.

3.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-461342

ABSTRACT

Objective To observe the effect of new moist dressings on pressure ulcers after spinal cord injury. Methods 58 spinal cord injured patients complicated with pressure ulcers were divided into observation group (n=29) and control group (n=29). The observation group accepted moist dressings, while the control group accepted routine dry dressings, TDP and ultraviolet irradiation. The incidence of im-provement were recorded 2 weeks after treatment, and the time of healing were compared. Results 11 cases cured, 17 cases relieved in the observation group, and it was 5 and 18 cases in the control group, respectively (P<0.05). It spent (26.69±16.48) days to cure in the observa-tion group, and (38.24±22.47) days in the control group (P<0.05). Conclusion The moist therapy may promote the cure of pressure ulcers af-ter spinal cord injury, and shorten the time of cure.

4.
Chinese Journal of Nursing ; (12): 418-420, 2010.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-402672

ABSTRACT

This paper summarizes nursing care of a patient with wound infection following systemic lupus erythematosus (SLE) accompanied by herpes zoster. Aimed at the patient's characteristics of long-term disease course of SLE,weak immune system caused by long-term use of glucocorticoid and immunosuppressant,big wound area with severe infection,and hard healing,moist therapy was implemented under the theoretical guidance of moist healing environment. The Purilon Gel and Biatain-Ag Foam dressing were applied in the wound combined with systemic use of antibiotics and treatment of SLE. At the same time,psychological nursing and health education were provided for the patient. These measures speeded up the wound healing.

5.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-585250

ABSTRACT

Objective: To study the effect of moist therapy on dermal radio lesions. Methods:13 located dermal radio lesions about Ⅲ-Ⅳ stage from 12 cases were treated with moist therapy. Wound managing steps for each time: The first step was to measure the size of wounds and take photos, and then evaluate individual pain level by a numeric pain scale. The second step was to assess and analyze the factors affecting wounds healing, including nutrition, sleeping, activity, psychological condition. After that the individualized plans about nutrition, activity, and psychological care were made. While exchanging dressings, the implementation and effects of the plans must be evaluated and adjusted. The mechanical debridement combined with autolyzing debridement was used for wounds managing. Then the wounds were saturated with bFGF and normal saline, and wetly covered with occlusive dressings. Wounds were managed every two days until wounds healed. Results: All 13 wounds were cured. The average healing time was (10?6)d and the average cost was (202?48)yuan. The pain level after moist therapy was significantly lowered than before(P

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