Association between the consumption of ultra-processed foods and the incidence of peptic ulcer disease in the SUN project: a Spanish prospective cohort study.

PURPOSE: Consumption of ultra-processed foods (UPF) has increased despite potential adverse health effects. Recent studies showed an association between UPF consumption and some gastrointestinal disorders. We evaluated the association between UPF consumption and peptic ulcer disease (PUD) in a large Spanish cohort. METHODS: We conducted a prospective analysis of 18,066 participants in the SUN cohort, followed every two years. UPF was assessed at baseline and 10 years after. Cases of PUD were identified among participants reporting a physician-made diagnosis of PUD during follow-ups. Cases were only partially validated against medical records. Cox regression was used to assess the association between baseline UPF consumption and PUD risk. Based on previous findings and biological plausibility, socio-demographic and lifestyle variables, BMI, energy intake, Helicobacter pylori infection, gastrointestinal disorders, aspirin and analgesic use, and alcohol and coffee consumption were included as confounders.We fitted GEE with repeated dietary measurements at baseline and after 10 years of follow-up. Vanderweele's proposed E value was calculated to assess the sensitivity of observed associations to uncontrolled confounding. RESULTS: During a median follow-up of 12.2 years, we recorded 322 new PUD cases (1.56 cases/1000 person-years). Participants in the highest baseline tertile of UPF consumption had an increased PUD risk compared to participants in the lowest tertile (HR = 1.52, 95% CI: 1.15, 2.00, Ptrend=0.002). The E-values for the point estimate supported the observed association. The OR using repeated measurements of UPF intake was 1.39 (95% CI: 1.03, 1.87) when comparing extreme tertiles. CONCLUSION: The consumption of UPF is associated with an increased PUD risk.

Adherence to the ultra-processed dietary pattern and risk of depressive outcomes: Findings from the NutriNet Brasil cohort study and an updated systematic review and meta-analysis.

BACKGROUND & AIMS: We aimed to analyze the prospective association between adherence to the ultra-processed dietary pattern and risk of depressive outcomes using original data from the NutriNet Brasil cohort and via a systematic review and meta-analysis of observational studies that have investigated the same association. METHODS: In our original research analysis, we used data from 15,960 adults (≥18 y) participating in the NutriNet Brasil cohort study, free of depression or depressive symptoms during the baseline (77.5% women, 45.8 ± 13.0 y). The mean dietary share of ultra-processed foods (%Kcal/d), calculated from two baseline 24-h dietary recalls, was used to measure the adherence to the ultra-processed dietary pattern. New cases of depressive symptoms were assessed using the Patient Health Questionnaire-9 over the follow-up period (mean: 18.3 months). Cox proportional hazards models were used for the main analyses. In our systematic review and meta-analysis, we incorporated effect estimates from six prospective cohort studies that have examined the same association, including ours. RESULTS: In the adjusted model, each 10% increase in the dietary share of ultra-processed foods was associated with a 10% increase in the hazard of incident cases of depressive symptoms (HR:1.10; 95%CI: 1.07-1.14). This association was slightly attenuated in the models including potential mediators. In our meta-analysis of six prospective studies, high versus low exposure to ultra-processed foods was associated with a summary hazard ratio of depressive outcomes of 1.32; 95%CI: 1.19-1.46; I2: 71%. CONCLUSION: A higher adherence to the ultra-processed dietary pattern was associated with a higher risk of developing depressive outcomes in the NutriNet Brasil cohort and in the meta-analysis.

Is Ultra-Processed Food Intake Associated with a Higher Risk of Glaucoma? A Prospective Cohort Study including 19,255 Participants from the SUN Project.

OBJECTIVE: The aim of this study was to examine the relationship of ultra-processed food (UPF) intake with the incidence of glaucoma in a large sample of Spanish university graduates followed prospectively. METHODS: Prospective cohort study using data from the SUN Project. A final sample of 19,225 participants (60.1% women) was included in this study, with a mean age of 38.2 years (standard deviation (SD) = 12.4). Participants were followed-up for a mean time of 12.9 years (SD = 5.4). Dietary intake was measured using a 136-item semiquantitative food-frequency questionnaire. UPFs were defined based on the NOVA classification system. Glaucoma diagnosis was determined by asking the participants if they had ever been diagnosed with glaucoma by an ophthalmologist. This self-reported diagnosis of glaucoma has been previously validated. RESULTS: After adjusting for several covariates, participants with the highest UPF consumption were at higher risk of glaucoma (hazard ratio (HR) = 1.83; 95% confidence interval (CI) 1.06 to 3.17) when compared to participants in the lowest category of UPF consumption. Regarding subgroup analyses, a significant multiplicative interaction was found for age (p = 0.004) and omega 3:6 ratio (p = 0.040). However, an association between UPF consumption and glaucoma was only found in older participants (aged ≥ 55 years), in men, in the most physically active group, in the group of non- or former smokers, in those with a lower omega 3:6 ratio, and in those with a lower energy intake. Regarding the contribution of each type of UPF group, UPF coming from sweets showed a significant risky effect (HR = 1.51; CI 95% 1.07 to 2.12). CONCLUSIONS: This prospective cohort study shows that participants with a greater UPF consumption have a higher risk of developing glaucoma when compared to participants with a lower consumption. Our findings emphasize the relevance of monitoring and limiting the consumption of UPFs as a means of preventing glaucoma incidence.

The degree of food processing contributes to sugar intakes in families with preschool-aged children.

BACKGROUND AND AIMS: Evidence implicates ultra-processed food intake as a major contributor of excess dietary sugars. However, little research exists on the relationship between the degree of food processing and sugar intake in families with young children. We investigated associations between the degree of food processing and sugar intake (total and free sugars) in Canadian preschool-aged children and parents. METHODS: This cross-sectional study of 242 families included preschool-aged children (n = 267) and parents (n = 365) participating in the Guelph Family Health Study. Dietary intake was assessed via the web-based Automated Self-Administered 24-h Dietary Assessment Tool (ASA24-Canada-2016) and classified according to the NOVA Food Classification System including, unprocessed or minimally processed foods, processed culinary ingredients, processed foods and ultra-processed foods. Linear regression models with generalized estimating equations were used to examine associations between the energy contribution of each NOVA classification category and sugar intake (% kcal of total and free sugars). Pearson correlation coefficient estimates were used to assess dietary relationships between parents and children. RESULTS: Ultra-processed foods were the greatest source of energy (44.3%) and energy from total (8.7%) and free sugars (7.3%) in the parents' diets, and the greatest source of energy (41.3%) and energy from free sugars (7.6%) in the children's diet. Ultra-processed food intake was positively associated with sugar intake in parents (total sugars: B = 0.05, 95% CI: 0.02-0.09, p = 0.01; free sugars: B = 0.11, 95% CI: 0.08-0.15, p < 0.001) and children (total sugars: B = 0.10, 95% CI: 0.04-0.16, p = 0.001; free sugars: B = 0.16, 95% CI: 0.12-0.21, p < 0.001). Unprocessed or minimally processed food intake was negatively associated with free sugar intake in parents (B = -0.08, 95% CI: -0.12 to -0.05, p < 0.001) and children (B = -0.15, 95% CI: -0.19 to -0.10, p < 0.001). Weak correlations were found between parents and children for processed culinary ingredients and ultra-processed processed food intake (p < 0.001). CONCLUSIONS: This study highlights the associations between degree of food processing and sugar intake in parents and children, whereby ultra-processed foods were positively, and unprocessed or minimally processed foods were negatively, associated with sugar intake. These are important considerations in the development of policy and recommendations for foods to potentially promote or limit.

A novel web-based 24-h dietary recall tool in line with the Nova food processing classification: description and evaluation.

OBJECTIVE: This paper describes the first web-based self-completed 24-h recall designed to categorise food intake according to Nova groups - Nova24h - and its agreement with a reference tool in estimating the dietary relative contribution of the four Nova food groups (% of total energy intake). DESIGN: Comparisons of estimates of dietary relative contributions of Nova groups obtained by Nova24h and one standard interviewer-led 24-h recall. SETTING: Nationwide adult cohort study in Brazil. PARTICIPANTS: The subjects were 186 participants of the NutriNet Brasil Cohort Study (n 186). RESULTS: No statistically significant differences were observed between the Nova24h and the reference tool mean contributions of unprocessed or minimally processed foods (52·3 % v. 52·6 %), processed culinary ingredients (11·6 % v. 11·9 %), processed foods (17·1 % v. 14·7 %) and ultra-processed foods (19·0 % v. 20·9 %). Intraclass correlation coefficients between individual estimates obtained for each Nova group showed moderate to good agreement (0·54-0·78). Substantial or almost perfect agreement between the tools was seen regarding the ability to rank participants according to quintiles of contribution of each Nova group (PABAK 0·69-0·81). CONCLUSIONS: Nova24h is a suitable tool for estimating the dietary relative energy contribution of Nova food groups in the NutriNet Brasil cohort. New studies are necessary to verify its adequacy in other populations.

Profiling ultra-processed foods in Thailand: sales trend, consumer expenditure and nutritional quality.

BACKGROUND: Ultra-processed foods (UPF) are associated with adverse health outcomes. This study aimed to analyse the national trends in retail sales, consumer expenditure and nutritional quality of UPFs in Thailand. METHODS: The study used data from the Euromonitor Passport database for analysis of retail sales and consumer expenditure, and from the Mintel Global New Products Database for nutritional analysis using the WHO Southeast Asian Region nutrient profile model. RESULTS: The study found the highest per capita sales volume and value of UPFs in 2021 were sauces, dressings & condiments (8.4 kg/capita) and carbonated soft drinks (27.1 L/capita), respectively. However, functional & flavoured water, ready-made meals and baked goods had the highest observed (2012-2021) and expected (2021-2026) sales growth. Supermarkets were responsible for most of the UPF sales since 2012, but convenience stores had larger growth in retail values. Growth in consumer expenditure per capita on UPFs from 2012 to 2020, ranged between 12.7% and 34%, and till 2026 is forecast to grow between 26% and 30%. More than half of UPFs exceeded at least one nutrient cutoff, 59.3% for total fats, 24.8% for saturated fats, 68.2% for total sugars and 94.3% for sodium. CONCLUSIONS: The findings suggest a need for regulatory and non-regulatory measures such as UPF taxation and marketing restrictions, and market incentives for producing non-UPFs. A system for regularly monitoring and evaluating healthiness (both nutritional and processing aspects) of food products, especially UPFs, is required.

Choosing an effective food classification system for promoting healthy diets in Thailand: a comparative evaluation of three nutrient profiling-based food classification systems (government, WHO, and Healthier Choice Logo) and a food-processing-based food classification system (NOVA).

Introduction: This study aimed to assess the nutritional quality of food and beverage products in Thailand by comparing four different food classification systems: the nutrient profiling-based food classification systems by the Department of Health (DOH), the WHO South-East Asia Region (WHO SEA), the Healthier Choice Logo (HCL), and the food-processing-based food classification system, NOVA. Methods: This study used secondary data from the Mintel Global New Products Database (N = 17,414). Food subgroups were classified differently based on these four systems. The DOH classified food products into three groups: Group A-healthy pass or meeting standard, Group B-not meeting the standard, and Group C-far below standard. The WHO SEA classified food products into two groups: marketing prohibited products and marketing permitted products. The HCL classified food products into two groups: eligible products for the logo; and ineligible products for the logo. The NOVA classified food products into four groups: unprocessed or minimally processed foods (MP), processed culinary ingredients (PCI), processed foods (P), and ultra-processed foods (UPF). Descriptive statistics (percentage and frequency) were used for analysis. Agreement analysis was conducted using Cohen's kappa statistic between each pair of food classification systems. Results: Of the total sample that could be classified by any of the four classification systems (n = 10,486), the DOH, the WHO SEA and the HCL systems classified products as healthy (Group A, marketing permitted or eligible for HCL logo) at 10.4, 11.1, and 10.9%, respectively. Only 5.6% were classified as minimally processed foods using NOVA and 83.1% were ultra-processed foods (UPFs). Over 50% of products classified as healthy by the nutrient profiling systems were classified as UPF according to the NOVA system. Products that were eligible for the HCL had the highest proportion of UPF products (84.4%), followed by the Group A products (69.2%) and the WHO marketing-permitted products (65.0%). Conclusion: A hybrid food classification approach taking both nutrients and food processing into account is needed to comprehensively assess the nutritional quality of food and beverage products in Thailand.

The degree of food processing is associated with anthropometric measures of obesity in Canadian families with preschool-aged children.

Adopting a healthy diet remains central for the prevention of obesity. In adults, higher intake of ultra-processed food is associated with a greater risk of overweight and obesity. However, little is known about the degree of food processing and its association with anthropometric measures in families with preschool-aged children, a critical period for the development of dietary patterns. This cross-sectional study included preschool-aged children (n = 267) between 1.5 and 5 years of age and their parents (n = 365) from 242 families enrolled in the Guelph Family Health Study. Dietary assessment was completed using ASA24-Canada-2016. Foods and beverages were classified based on their degree of food processing using the NOVA Classification (unprocessed or minimally processed foods, processed culinary ingredients, processed foods, and ultra-processed foods). Associations between the energy contribution (% kcal) of each NOVA category and anthropometric measures were examined using linear regression models with generalized estimating equations, adjusted for sociodemographic variables. The energy contribution of ultra-processed foods was the highest relative to the other NOVA categories among parents (44.3%) and children (41.3%). The energy contribution of unprocessed or minimally processed foods was 29.1% for parents and 35.3% for children, processed foods was 24.0% for parents and 21.3% for children, and processed culinary ingredients was 2.6% for parents and 2.1% for children. Ultra-processed foods (% kcal) were positively associated with BMI (ß = 0.04, 95% CI: 0.01-0.07, P = 0.02), waist circumference (ß = 0.11, 95% CI: 0.03-0.18, P = 0.008) and body weight (ß = 0.13, 95% CI: 0.03-0.22, P = 0.01) in parents, but not children. Unprocessed foods (% kcal) were negatively associated with waist circumference in parents (ß = -0.09, 95% CI: 0.18-0.01, P = 0.03) and children (ß = -0.03, 95% CI: 0.05-0.01, P = 0.01), as well as body weight (ß = -0.12, 95% CI: 0.23-0.00, P = 0.04) in parents. The degree of food processing primarily influenced anthropometric outcomes in parents. Nevertheless, diets of children were similar, suggesting that such exposure in families may eventually lead to outcomes observed in parents.

A Semi-quantitative Food Frequency Questionnaire Has Relative Validity to Identify Groups of NOVA Food Classification System Among Mexican Adults.

BACKGROUND: Ultra-processed foods are recognized as indicators of an unhealthy diet in epidemiological studies. In addition to ultra-processed foods, the NOVA food classification system identifies three other groups with less processing. Unprocessed foods that, together with minimally processed foods (MPF), make NOVA group 1, NOVA group 2 is processed culinary ingredients, and NOVA group 3 is processed foods. OBJECTIVE: To assess the relative validity of the semi-quantitative food frequency questionnaire (SFFQ) to estimate the energy intake for each group NOVA classification system by comparing it with two 24 h-dietary-recall (24DRs) Mexican adults. METHODS: We analyzed dietary information from 226 adults included <60 and ≥60 years with complete SFFQ and two 24DRs from the National Health and Nutrition Survey 2012. We reported mean differences, Spearman correlation coefficients, intra-class correlations coefficients, Bland-Altman plots, and weighted kappa between measures. RESULTS: The percentage energy intake from unprocessed and minimally processed foods group, Spearman correlation coefficients was 0.54 in adults <60 years and 0.42 in adults ≥60 years, while ultra-processed foods group was 0.67 and 0.48, respectively. The intra-class correlation coefficients in the unprocessed and minimally processed foods group was 0.51 in adults <60 years and 0.46 in adults ≥60 years, and for the ultra-processed foods group were 0.71 and 0.50, respectively. Bland-Altman plots indicated reasonably consistent agreement for unprocessed and minimally processed foods group and ultra-processed foods group in adults <60 years and adults in the ≥60 age group. Weighted kappa was 0.45 in the ultra-processed foods group to adults <60 years and was 0.36-≥60 years. CONCLUSION: The SFFQ had acceptable validity to rank the percentage of energy intake from unprocessed and minimally processed foods group and ultra-processed foods group in Mexican adults, both in adults under 60 years and who were 60 years old or older.

Ultra-processed foods and type-2 diabetes risk in the SUN project: A prospective cohort study.

BACKGROUND & AIM: The association between ultra-processed foods (UPF) consumption and the risk of type 2 diabetes (T2D) has not been much explored. We aimed to evaluate the association between consumption of UPF and the incidence of T2D. METHODS: We assessed 20,060 participants (61.5% women) from the SUN project (Seguimiento Universidad de Navarra) followed-up every two years (median follow-up 12 years). Food and drink consumption were evaluated through a validated 136-item food frequency questionnaire and grouped according to their degree of processing by the NOVA classification. Participants were categorized into tertiles of UPF consumption adjusted for total energy intake. We fitted Cox proportional hazard models with repeated dietary measurements at baseline and updating information on food consumption after 10 years of follow-up to minimise the potential effect of diet variation. RESULTS: During 215,149 person-years of follow-up, 175 new-onset T2D cases were confirmed. Participants in the highest baseline tertile (high consumption) of UPF consumption had a higher risk of T2D as compared to those in the lowest tertile (multivariable adjusted hazard ratio [HR] 1.53, 95% confidence interval [CI]: 1.06 to 2.22) with a significant dose-response relationship (p for linear trend = 0.024). The multivariable adjusted HR using repeated measurements of UPF intake was 1.65 (95% CI 1.14-2.38) when comparing extreme tertiles. CONCLUSIONS: In a highly-educated Mediterranean cohort with a low absolute risk, a higher intake of UPF was independently associated with a higher risk for T2D. These results provide more evidence to encourage the limitation of UPF consumption to reduce the population burden of T2D.

Evolução do consumo de nutrientes e de alimentos segundo a classificação NOVA em frequentadores de serviço de promoção da saúde da atenção primária / Evolution of nutrient and food consumption according to the NOVA classification among users of health promotion service in primary health care

INTRODUÇÃO: Consumir alimentos in natura, minimamente processados e preparações culinárias (PC), em detrimento aos ultraprocessados (AUP), pode melhorar o perfil nutricional da dieta e reduzir o risco de desenvolvimento de doenças crônicas não transmissíveis (DCNT). OBJETIVO: Avaliar a evolução do consumo de nutrientes e de alimentos, segundo a classificação NOVA, após intervenção coletiva de incentivo ao consumo de frutas e hortaliças (FH) em usuários do Programa Academia da Saúde (PAS) de Belo Horizonte, Minas Gerais. MÉTODOS: Foram desenvolvidos três artigos com dados oriundos de ensaio comunitário controlado e randomizado (ECCR), conduzido entre 2013 ­ 2015, com amostra representativa das unidades do PAS de Belo Horizonte, sendo 9 unidades pertencentes ao Grupo Controle (GC) e 9 ao Grupo Intervenção (GI). Indivíduos alocados no GC participaram das atividades rotineiras do serviço de saúde (prática regular de exercícios físicos três vezes/semana) e aqueles do GI adicionalmente receberam, durante sete meses, intervenção de incentivo ao consumo de FH, pautada no Modelo Transteórico e na pedagogia dialógica e problematizadora de Paulo Freire. Artigo 1: Estudo transversal realizado com dados da linha de base do ECCR que objetivou analisar o consumo de AUP segundo fatores sociodemográficos, e sua associação com o perfil nutricional da dieta. O perfil nutricional da dieta foi analisado segundo os quintis de contribuição percentual de energia oriunda de AUP mediante análises de associação e de Regressão Linear referente ao consumo de energia total, densidade energética, carboidratos, fibras, proteínas, gorduras totais e subgrupos de gorduras: saturada, monoinsaturada, poli-insaturada, trans, ômega 3 e ômega 6, vitaminas A, B3, B6, B12, Folato e C; e os minerais cálcio, ferro, fósforo, magnésio, potássio e sódio. Além disso, avaliou-se o percentual de inadequação do consumo de nutrientes recomendados para prevenção de DCNT e do consumo de vitaminas por Regressão de Poisson. Artigo 2: ECCR que objetivou verificar a efetividade de intervenção coletiva de incentivo ao consumo de FH sobre o consumo de alimentos, segundo a classificação NOVA, em frequentadores de serviço de promoção da saúde da Atenção Primária em Saúde (APS) brasileira. Os desfechos analisados foram consumo de PC, de alimentos processados (AP) e de AUP por meio de análises de associação e de comparação entre GC e GI, e Equações de Estimações Generalizadas (GEE). Artigo 3: ECCR que objetivou verificar a efetividade de intervenção coletiva de incentivo ao consumo de FH sobre a adequação do consumo de nutrientes, especialmente aqueles voltados para prevenção de DCNT, em frequentadores de serviço de promoção da saúde da APS brasileira. Também foram utilizadas análises de associação e GEE entre os grupos GI e GC. Os nutrientes analisados foram: energia total, carboidratos, fibras, proteínas, gorduras totais e subgrupos de gorduras: saturada, monoinsaturada, poli-insaturada, trans, ômega 3 e ômega 6, vitaminas A, B1, B2, B3, B6, B12, Folato, C, D, E; e os minerais cálcio, ferro, fósforo, magnésio, manganês, potássio, selênio, sódio e zinco. RESULTADOS - Artigo 1: O consumo de AUP contribuiu com 27,7% da energia total da dieta. O seu maior consumo associou a maiores valores de ingestão de energia, densidade de energia, gorduras totais e sódio; e menores de proteínas, gorduras monoinsaturadas, ômega 3 e algumas vitaminas e minerais. A prevalência de inadequação de nutrientes para prevenção de DCNT variou entre 30% e 100% entre o menor e maior quintil de consumo de AUP. Artigo 2: Após 12 meses de acompanhamento, observou-se entre os indivíduos do GI e do GC, aumento no consumo de PC e redução de AUP; além de aumento no consumo de AP entre os indivíduos do GC. Foi observado que a intervenção nutricional contribuiu para redução do consumo de AP para indivíduos alocados no primeiro quartil (RR: 0.861; CI: 0.749; 0.988) e aumento para aqueles alocados no segundo quartil de consumo de AP (RR: 1.145; CI: 1.041; 1.259). Também foi observada relação entre participação na intervenção nutricional e aumento do consumo de AUP para indivíduos alocados no terceiro quartil de consumo de AUP (RR: 1,062; CI: 1,005; 1,122). Artigo 3: Participantes dos grupos GC e GI, após 12 meses, apresentaram redução no consumo de energia, ômega 6 e sódio; e aumento de carboidratos, fibras, vitaminas A, B1, B2, B3, B6, B12, C, D e E, folato, cálcio, magnésio, potássio, selênio, manganês, zinco e ferro. Indivíduos do GC relataram ainda aumento do consumo de fósforo; e aqueles do GI, redução do consumo de gorduras totais, saturadas e poli-insaturadas; e aumento de monoinsaturadas. Em ambos os grupos, observou-se aumento na prevalência de adequação de nutrientes para prevenção de DCNT, exceto para gorduras trans. A participação na intervenção nutricional mostrou relação inversa com o consumo de energia (RR: 0,979; CI: 0,960; 0,999) e proteínas (RR: 0,978; CI: 0,959; 0,997) da dieta, mas não aumentou a chance de adequação dos demais nutrientes, incluindo aqueles voltados para prevenção de DCNT. CONCLUSÃO: Os resultados apontaram para a importância do PAS, um serviço de promoção da saúde do Sistema Único de Saúde, para a promoção da alimentação adequada e saudável, e prevenção das DCNT. A condução de intervenção coletiva de incentivo ao consumo de FH apresentou poucos resultados adicionais, evidenciando a necessidade de se realizar abordagens específicas relativas à classificação NOVA de alimentos visando alcançar melhores resultados.

INTRODUCTION: Consuming fresh, minimally processed foods and culinary preparations (CP), in detriment to ultra-processed foods (UPF), can improve the nutritional profile of the diet and reduce the risk of developing chronic non-communicable diseases (NCD). OBJECTIVE: Evaluating the evolution of nutrient and food consumption, according to the NOVA classification, after conducting a collective intervention to encourage the consumption of fruits and vegetables (FV) among users of the Health Academy Program (Programa Academia da Saúde - PAS) in Belo Horizonte, Minas Gerais. METHODS: Three articles were developed with data from a randomized controlled community trial (ECCR), conducted between 2013 and 2015, with a representative sample of the PAS units in Belo Horizonte, with 9 units belonging to the Control Group (CG) and 9 to the Intervention Group (IG). Individuals allocated to the CG participated in the routine activities of the health service (regular practice of physical exercise three times/week) and those in the IG additionally received, for seven months, an intervention to encourage the consumption of FV, based on the Transtheoretical Model and on the dialogical and problematizing pedagogy of Paulo Freire. Article 1: Cross-sectional study carried out with baseline data from the ECCR, which aimed to analyze the consumption of UPF according to sociodemographic factors, and its association with the nutritional profile of the diet. The nutritional profile of the diet was analyzed according to the quintiles of percentage contribution of energy from UPF through association and Linear Regression analyzes regarding total energy consumption, energy density, carbohydrates, fiber, proteins, total fat and fat subgroups: saturated, monounsaturated, polyunsaturated, trans, omega 3 and omega 6, vitamins A, B3, B6, B12, folate and C; and the minerals calcium, iron, phosphorus, magnesium, potassium and sodium. In addition, the percentage of inadequate consumption of nutrients recommended for the NCD prevention and the consumption of vitamins were evaluated by Poisson Regression. Article 2: ECCR which aimed to verify the effectiveness of collective intervention to encourage the consumption of FV on food consumption, according to the NOVA classification, among users of health promotion services in the Brazilian Primary Health Care (PHC). The outcomes analyzed were consumption of CP, processed foods (PF) and UPF through association and comparison analysis between CG and IG, and Generalized Estimating Equation (GEE) analysis. Article 3: ECCR which aimed to verify the effectiveness of a collective intervention to encourage the consumption of FV on the adequacy of nutrient intake for NCD prevention in health promotion service users of the Brazilian PHC. Association, comparison and GEE analyzes were also used between the GI and CG groups. The analyzed nutrients were total energy, carbohydrates, fiber, protein, total fat and fat subgroups: saturated, monounsaturated, polyunsaturated, trans, omega 3 and omega 6, vitamins A, B1, B2, B3, B6, B12, folate, C, D and E; and the minerals calcium, iron, phosphorus, magnesium, manganese, potassium, selenium, sodium and zinc. RESULTS - Article 1: The consumption of UPF contributed with 27.7% of the total energy of the diet. Its higher consumption was associated with higher values of energy intake, energy density, total fat and sodium; and smaller proteins, monounsaturated fats, omega 3 and some vitamins and minerals. The prevalence of inadequacy of nutrients for the NCD prevention ranged between 30% and 100% between the lowest and highest quintile of consumption of UPF. Article 2: After 12 months of follow-up, there was an increase in CP consumption and a reduction in UPF among individuals in the IG and CG; in addition to an increase in PF consumption among individuals in the CG. It was observed that the nutritional intervention contributed to a reduction in AP consumption for individuals allocated to the first quartile (RR: 0.861; CI: 0.749; 0.988) and an increase for those allocated to the second quartile of AP consumption (RR: 1,145; CI: 1,041; 1,259). A relationship was also observed between participation in the nutritional intervention and increased consumption of UPF for individuals in the third quartile of AUP consumption (RR: 1.062; CI: 1.005; 1.122). Article 3: Participants in the CG and IG groups, after 12 months, showed a reduction in the consumption of energy, omega 6 and sodium; and increased carbohydrates, fiber, vitamins A, B1, B2, B3, B6, B12, C, D and E, folate, calcium, magnesium, potassium, selenium, manganese, zinc and iron. Individuals from the CG showed an increase in phosphorus consumption; and those of the IG, reduction in the consumption of total, saturated and polyunsaturated fats; and increased monounsaturated. In both groups, there was an increase in the prevalence of nutrient adequacy for the NCD prevention, except for trans fats. Participation in nutritional intervention showed an inverse relationship with dietary energy (RR: 0,979; CI:0,960; 0,999) and protein intake (RR: 0,978; CI: 0,959; 0,997), but did not increase the chance of adequacy of nutrient intake for NCD prevention. CONCLUSION: The results pointed to the importance of the PAS, a health promotion service of the Unified Health System, for the promotion of adequate and healthy food, and NCD prevention. The conduction of collective intervention to encourage the consumption of FV showed few additional results, highlighting the need to carry out specific approaches related to the NOVA classification of foods in order to achieve better results.