ABSTRACT
Neonatal necrotizing enterocolitis(NEC)is a life-threatening intestinal disease in newborns, and early identification of NEC is a major clinical challenge.Although clinical manifestations, routine laboratory tests and imaging examinations are essential for NEC, more and more studies in recent years based on the understanding of the pathogenesis of NEC have reported that NEC-related biomarkers such as fatty acid-binding proteins, cytokines, and intestinal flora have potential value in its prediction, early diagnosis, severity assessment and prognosis.This review will discuss the biomarkers related to NEC that have been studied in recent years from three aspects: blood, urine and feces, so as to guide clinical application.
ABSTRACT
Background: As an end stoma, Santulli enterostomy provides early restoration of intestinal continuity without formal laparotomy. Short amputation of the common limb enables closure on a side to restore anatomic continuity without sacrificing valuable intestine; additionally, the procedure is simple and safe. Most newborns who require enterostomy might benefit from Santulli enterostomy; however, several pediatric surgeons lack information regarding this procedure. Therefore, we have reviewed our experience about Santulli enterostomy and explore the advantages and indications in neonatal intestinal conditions. Methods: The clinical data of 76 neonates who underwent enterostomywere obtained. The patients were divided into two groups: the Santulli group with 33 cases who underwent Santulli enterostomy, and the control group with 43 cases who underwent double- or single-lumen ostomy. The general data of the two groups were analyzed, and the perioperative/postoperative complications, clinical data and the long-term outcomes were compared. Results: There was no difference in the demographic informations, the level of enterostomy, the rate of high-sight stoma, the operative time and bleeding of enterostomy between the two groups. Compared to the control group, the operative time of ostomy closure was less in the Santulli group (53.00 vs. 152.47, P < 0.001). The duration of parenteral nutrition (27.45 vs. 44.56, P = 0.010), the mean interval of initial enterostomy to stomal closure (131.21 vs. 216.42, P < 0.001), and length of stay (46.00 vs. 67.60, P = 0.007) were shorter, while the incidence of postoperative complications and hospitalization costs (11.21 vs. 15.49, P = 0.006) were lower. The Santulli procedure can reduce the morbidity of high output ostomy (2 vs. 10, P = 0.042) and short bowel syndrome (3 vs. 132, P = 0.025), shorten the discrepancy of diameter between the proximal and distal segments, maximize the available intestine, and monitor the movement of the distal bowel. The length of incision was shorter, and the catch-up growth was significantly faster in the Santulli group. Conclusion: Santulli enterostomy is a superior procedure in the treatment of neonatal intestinal conditions, in terms of fewer complications, faster catch-up growth, shorter hospitalization time and treatment duration. It should be the procedure of choice in several newborns with intestinal conditions that require ostomy.
ABSTRACT
RESUMEN Introducción: la Academia Americana de Pediatría define a los cuidados Intensivos como aquellos que recibe el recién nacido gravemente enfermo o los que requieren de una vigilancia estricta de los profesionales de la unidad neonatal. La calidad de la atención sanitaria es un atributo cada vez más valorado por todos los implicados en la atención a la salud (profesionales, usuarios y gestores) aunque cada uno de estos grupos enfatiza algunos aspectos en particular con relación al resto. Objetivo: evaluar la calidad de la atención de Enfermería en el Servicio de Neonatología. Métodos: se realizó un estudio descriptivo, prospectivo y longitudinal en el Servicio de Neonatología del Hospital Infantil Norte Docente "Juan De La Cruz Martínez Maceira" de Santiago de Cuba en el periodo enero-diciembre de 2013. El universo lo constituyeron 754 pacientes egresados del servicio, sus madres acompañantes y 40 enfermeras que se encontraban laborando en el servicio. Se confeccionaron indicadores de calidad con estándares establecidos para estructura, proceso y resultado, se aplicó un instrumento evaluativo a las enfermeras y encuesta de satisfacción a las madres de los neonatos. Resultados: el indicador estructura alcanzó estándares no aceptables en cuanto a equipamiento no apto para su uso y la estructura del servicio, en el proceso y resultados todos sus indicadores fueron evaluados de aceptables, existiendo buen grado de satisfacción de la totalidad de las madres que acudieron con sus bebitos. Conclusión: no se detectaron dificultades en los indicadores de proceso y resultados evidenciando que existe calidad de la atención de enfermería en el servicio de neonatología(AU)
ABSTRACT Introduction: You define Pediatría's American Academy as intensive care those that you receive the gravely sick newborn baby or the ones that call for a close watch of the professionals of the neo-natal unit. The quality of the sanitary attention is an attribute more and more appraised for all the implicated in the attention to health (professionals, users and managers) although each one of these groups emphasizes some aspects in particular with respect to the rest. Objective: Evaluating the quality of Enfermería's attention in Neonatología's Service. Methods: Juan De accomplished a Descriptive, prospective and longitudinal study himself, in Neonatología's Service of the Infantile North Teaching Hospital James's Cross Martínez Maceira of Cuba in the period January December 2013. The universe was constituted by 754 patients left of the service, his accompanying mothers and 40 nurses that were meeting laboring in the service. They manufactured indicators of quality with standards established for structure, process and result, evaluativo applied over itself an instrument to the nurses and polls of satisfaction the mothers of the neo-born. Results: The indicator structure caught up with standards not acceptable as to unsuited equipamiento for his use and the structure of the service, in the process and once all his indicators were proven to be they were evaluated of acceptable, existing good grade of satisfaction of the totality of the mothers that attended with his little babies. Conclusion: They did not detect difficulties in the indicators of process and results evidencing that quality of the attention of infirmary in neonatología's service exists(AU)
