Subject(s)
Autoimmune Diseases , Factitious Disorders , Psychotic Disorders , Skin Diseases, Vascular , HumansABSTRACT
INTRODUCTION: Gardner-Diamond syndrome is a rare condition secondary to a sensitization to self-erythrocytes. It is predominantly seen in women and presents as a painful ecchymotic disorder. An underlying psychiatric disease or a triggering psychological stress is of important diagnostic value. CASE REPORT: We report a 24-year-old patient who presented with intermittent spontaneous painful ecchymosis since 5 years. Complementary investigations failed to identify an organic disorder. Gardner-Diamond syndrome was retained because of the clinical presentation, the negativity of diagnostic work-up and the identification of a psychological trauma. Patient management (pain, psychological support) is difficult, justifying a multidisciplinary approach. CONCLUSION: Gardner-Diamond syndrome is a rare and unrecognized disorder, which should be discussed in the presence of ecchymotic or purpuric lesions that do not have a diagnostic orientation. Early recognition of this disorder enables initiation of an appropriate management, but also limits unnecessary additional explorations.
Subject(s)
Autoimmune Diseases/diagnosis , Factitious Disorders/diagnosis , Psychotic Disorders/diagnosis , Skin Diseases, Vascular/diagnosis , Autoimmune Diseases/genetics , Autoimmune Diseases/pathology , Diagnosis, Differential , Factitious Disorders/genetics , Factitious Disorders/pathology , Humans , Male , Psychotic Disorders/genetics , Psychotic Disorders/pathology , Skin Diseases, Vascular/genetics , Skin Diseases, Vascular/pathology , Young AdultABSTRACT
Gardner–Diamond syndrome (GDS), or autoerythrocyte sensitisation, is a rare cause of recurrentpainful bruising with a typical anamnesis and prodrome. We describe a patient with GDS and discussthe literature surrounding this unique condition.
Subject(s)
Autoimmune Diseases/diagnosis , Psychotic Disorders/diagnosis , Skin Diseases, Vascular/diagnosis , Antidepressive Agents/therapeutic use , Anxiety Disorders/diagnosis , Anxiety Disorders/therapy , Autoimmune Diseases/therapy , Factitious Disorders/diagnosis , Factitious Disorders/therapy , Female , Humans , Pain/diagnosis , Pain/psychology , Psychotherapy , Psychotic Disorders/therapy , Skin Diseases, Vascular/therapy , Young AdultABSTRACT
Psychogenic purpura, also known as Gardner-Diamond syndrome, is a rare, distinctive, localized cutaneous reaction pattern mostly affecting psychologically disturbed adult women. Repeated crops of tender, ill-defined ecchymotic lesions on the extremities and external bleeding from other sites characterize the condition. We report here a case of psychogenic purpura because of the rarity of the condition and to emphasize the importance of consideration of this entity during evaluation of a patient with recurrent ecchymoses. Early diagnosis of this condition will not only minimize the cost of the medical evaluation but will also benefit the patient.
ABSTRACT
Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome), also known as painful bruising syndrome or psychogenic purpura, is characterized by sudden and spontaneous painful bruising and swelling on both extremities, and is a psychologically induced painful bruising condition. The exact etiology of the syndrome is an enigma, even today. It occurs primarily in young to middle-aged women who usually have psychogenic disorders. A diagnosis of this syndrome is made on the basis of the clinical history, dermatological examination complemented by a positive autoerythrocyte sensitization test, psychiatric evaluation and the absence of any organic cause. We present a 20-year-old man with characteristic features of this syndrome, who had a positive autoerythrocyte sensitization test. To our knowledge, this is the first case in an adult male reported in the Korean literature.
Subject(s)
Adult , Female , Humans , Male , Young Adult , Complement System Proteins , Diagnosis , Extremities , PurpuraABSTRACT
No abstract available.
ABSTRACT
Autoerythrocyte sensitization syndrome is characterized by sudden and spontaneous painful bruising and swelling occurring in adult female patients with emotional disorders. Systemic symptoms often accompany the onset of these lesions. A diagnosis of this syndrome can be made in a patient who has the typical history and clinical picture of the syndrome and in whom a skin test with the patient's blood reveals a positive reaction.
