Antibacterial Janus cellulose/MXene paper with exceptional salt rejection for sustainable and durable solar-driven desalination.

The scarcity of freshwater resources and increasing demand for drinking water have driven the development of durable and sustainable desalination technologies. Although MXene composites have shown promise due to their excellent photothermal conversion and high thermal conductivity, their high hydrophilicity often leads to salt precipitation and low durability. In this study, we present a novel Cellulose (CF)/MXene paper with a Janus hydrophobic/hydrophilic configuration for long-term and efficient solar-driven desalination. The paper features a dual-layer structure, with the upper hydrophobic layer composed of CF/MXene paper exhibiting convexness to serve as a photothermal layer with exceptional salt rejection properties. Simultaneously, the bottom porous layer made of CF acts as an efficient thermal insulation. This unique design effectively minimizes heat loss and facilitates efficient water transportation. The Janus CF/MXene paper demonstrates a high evaporation rate of 1.11 kg m-2h-1 and solar thermal conversion efficiency of 82.52 % under 1 sun irradiation. Importantly, even after 2500 h of operation in a simulated seawater environment, the paper maintains a stable evaporation rate without significant salt deposition and biodegradation due to an antibacterial rate exceeding 90 %. These findings highlight the potential of the Janus CF/MXene paper for scalable manufacturing and practical applications in solar-driven desalination.

Phenanthroimidazole-based fluorescence probe for discriminative detecting of hydrazine and bisulfite and its applications in environmental samples.

Hydrazine (N2H4) and bisulfite (HSO3-) detection methods are urgently needed due to its harmful to the human health and environment safety. Herein, we reported a dual-response fluorescence probe EPC, which is capable of sequential detection of N2H4 and HSO3- by two different fluorescence signals. The probe EPC itself showed yellow florescence. In presence of N2H4, probe EPC exhibited an obviously fluorescence change (from yellow to green). However, a new addition product came into being after probe EPC mixed with HSO3-, followed with weak yellow emission. More important, probe EPC exhibited excellent fluorescence response properties for N2H4 and HSO3-, such as high sensitivity (0.182 µM for N2H4, 0.093 µM for HSO3-), rapid response (55 s for N2H4, 45 s for HSO3-), excellent selectivity and anti-interference performance. The sensing mechanisms for N2H4 and HSO3- were proved by 1H NMR and MS spectra. Practical applications were studied. EPC based test paper can be utilized for quantitative detecting N2H4 in actual water samples. And, probe EPC has been successfully applied to recognize N2H4 contaminant in soil samples. Moreover, EPC has great potential to be used to detect HSO3- in real food samples.

Characteristics of the top 100 cited electroencephalography articles on aging: a bibliometric analysis.

Electroencephalography (EEG) is a widely used tool in neuroscience. To explore the features of the top 100 cited articles related to EEG and aging over the past decade, we conducted a bibliometric analysis using Web of Science Core Collection (WoSCC) data as of January 21, 2024. The selected top 100 cited papers were analyzed using VOSviewer and Excel. We examined the distribution of publication years, authors, institutions, countries/regions, and journals. Hotspots were identified through keyword analysis. The analyzed articles were published between 2014 and 2021, with the majority being published before 2020 (n=91). Citation counts in WoSCC ranged from 24 to 250, with a median of 40 and a mean of 53. A total of 818 authors from 283 institutions in 35 countries/territories contributed to these top papers. The United States of America (USA) (n=37), Germany (n=14), and Canada (n=11) ranked in the top three in terms of total publications or citations. The predominant journals were in the fields of Neuroscience (n=58), Geriatrics & Gerontology (n=22), Clinical Neurology (n=13), and Anesthesiology (n=9), which published most of the high-quality articles. Key themes included EEG, aging, Alzheimer's disease, mild cognitive impairment, functional connectivity, and alpha oscillations. Emerging topics included sleep, machine learning, delirium, postoperative cognitive function, virtual reality, monitoring, resting state, coherence, and transcranial direct current stimulation. In conclusion, this study provides a comprehensive overview of the trends in scientific literature on EEG in aging over the past decade. Authors and institutions from North America, Europe, and East Asia led in contributions. Journals focusing on neuroscience, geriatrics, and anesthesiology published the majority of articles. Degenerative neurological diseases and cognitive impairment were prominent topics, suggesting future studies should explore EEG's diagnostic utility for these disorders.

Effect of Carbon Fiber Paper with Thickness Gradient on Electromagnetic Shielding Performance of X-Band.

Flexible paper-based materials play a crucial role in the field of flexible electromagnetic shielding due to their thinness and controllable shape. In this study, we employed the wet paper forming technique to prepare carbon fiber paper with a thickness gradient. The electromagnetic shielding performance of the carbon fiber paper varies with the ladder-like thickness distribution. Specifically, an increase in thickness gradient leads to higher reflectance of the carbon fiber paper. Within the X-band frequency range (8.2-12.4 GHz), reflectivity decreases as electromagnetic wave frequency increases, indicating enhanced penetration of electromagnetic waves into the interior of the carbon fiber paper. This enhancement is attributed to an increased fiber content per unit area resulting from a greater thickness gradient, which further enhances reflection loss and promotes internal multiple reflections and scattering effects, leading to increased absorption loss. Notably, at a 5 mm thickness, our carbon fiber paper exhibits an impressive average overall shielding performance, reaching 63.46 dB. Moreover, it exhibits notable air permeability and mechanical properties, thereby assuming a pivotal role in the realm of flexible wearable devices in the foreseeable future.

Celebrating 10 Years of the HIMSS-SIIM Enterprise Imaging Community and Enterprise Imaging Informatics.

In response to the growing recognition of enterprise imaging as a critical component of healthcare's digital transformation, in 2014, the Healthcare Information and Management Systems Society (HIMSS) and the Society for Imaging Informatics in Medicine (SIIM) signed a Memorandum of Understanding to form the HIMSS-SIIM Enterprise Imaging Community (HSEIC). At the time of the agreement, the two organizations decided to collaborate to lead enterprise imaging development, advancement, and adoption. This paper celebrates the past 10 years of the HSEIC's thought leadership, industry partnerships, and impact while also looking ahead to identify enterprise imaging challenges to solve in the next decade.

Study Characteristics and Impact of the "Best Papers" Presented at ASSH Annual Meetings Over the Past Decade.

Purpose: Each year, the American Society for Surgery of the Hand (ASSH) selects several abstracts for podium presentations during a "Best Papers" session. We examined these papers to better understand their characteristics and impact on the field of hand surgery. Methods: "Best Papers" from the 2010 to 2020 ASSH Annual Meetings were reviewed. Online databases were searched to find matching publications. Descriptive data were collected from the publications. The Hirsch index value for each corresponding author and the number of citations for each publication were recorded. Descriptive statistics were used to analyze the data. Results: Fifty-nine "Best Papers" were awarded during the study period. Forty-nine (83%) were clinical and 10 were basic science studies. A total of 39 observational studies, 11 human trials, 8 experimental studies, and 1 case series were present. Fifty-four (91.5%) were published at the time of our review. Twenty-six of those (48%) were multicenter studies, and the remaining 28 were from a single institution. The average time from presentation to publication was 16 months. The top three journals of publication were the Journal of Hand Surgery (33%), the Journal of Bone and Joint Surgery (9%), and the Journal of Hand Surgery, European (7%). The median level of evidence for all "Best Papers" was 3, with a trend toward a higher level of evidence during the study period. The average h-index value of all corresponding authors was 27.3. The average number of citations per publication was 37. Conclusions: The ASSH "Best Papers" were primarily clinical studies with an increasingly strong level of evidence and were likely led by an author with a history of research productivity. Selection as a "Best Paper" at ASSH Annual Meetings is a strong predictor of future publication and impact. Clinical relevance: This study evaluates the "value" of the best paper designation at the ASSH annual meeting.

Top 20 EGFR+ NSCLC Clinical and Translational Science Papers That Shaped the 20 Years Since the Discovery of Activating EGFR Mutations in NSCLC. An Editor-in-Chief Expert Panel Consensus Survey.

The year 2024 is the 20th anniversary of the discovery of activating epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC). Since then, tremendous advances have been made in the treatment of NSCLC based on this discovery. Some of these studies have led to seismic changes in the concept of oncology research and spurred treatment advances beyond NSCLC, leading to a current true era of precision oncology for all solid tumors. We now routinely molecularly profile all tumor types and even plasma samples of patients with NSCLC for multiple actionable driver mutations, independent of patient clinical characteristics nor is profiling limited to the advanced incurable stage. We are increasingly monitoring treatment responses and detecting resistance to targeted therapy by using plasma genotyping. Furthermore, we are now profiling early-stage NSCLC for appropriate adjuvant targeted treatment leading to an eventual potential "cure" in early-stage EGFR+ NSCLC which have societal implication on implementing lung cancer screening in never-smokers as most EGFR+ NSCLC patients are never-smokers. All these advances were unfathomable in 2004 when the five papers that described "discoveries" of activating EGFR mutations (del19, L858R, exon 20 insertions, and "uncommon" mutations) were published. To commemorate this 20th anniversary, we assembled a global panel of thoracic medical oncology experts to select the top 20 papers (publications or congress presentation) from the 20 years since this seminal discovery with December 31, 2023 as the cutoff date for inclusion of papers to be voted on. Papers ranked 21 to 30 were considered "honorable mention" and also annotated. Our objective is that these 30 papers with their annotations about their impact and even all the ranked papers will serve as "syllabus" for the education of future thoracic oncology trainees. Finally, we mentioned potential practice-changing clinical trials to be reported. One of them, LAURA was published online on June 2, 2024 was not included in the list of papers to be voted on but will surely be highly ranked if this consensus survery is performed again on the 25th anniversay of the discovery EGFR mutations (i.e. top 25 papers on the 25 years since the discovery of activating EGFR mutations).

Innovative chitin-glucan based material obtained from mycelium of wood decay fungal strains.

Fungi are an alternative source to animal-based chitin. In fungi, chitin fibrils are strongly interconnected and bound with glucans that justify the unique matrix. The present study aimed to extract chitin and glucans from the mycelium of several wood decay fungal strains in order to obtain flexible materials and to check correlations between chitin content and the mechanical properties of these materials. Five strains were chosen in consideration of their different cell wall chemical composition (high content of α-glucans, ß-glucans or chitin) to evaluate how these differences could influence the mechanical and chemical characteristics of the material. The fungal strains were cultivated in liquid-submerged dynamic fermentation (both flasks and bioreactor). Chitin and glucans were crosslinked with acetic acid and plasticized with glycerol to obtain flexible sheets. Abortiporus biennis, Fomitopsis iberica and Stereum hirsutum strains were found to adapt to produce material with adequate flexibility. The obtained materials were characterized by Thermogravimetric analysis (TGA) for the understanding of the material composition. The material obtained from each species was mechanically tested in terms of tear strength, elongation at break, and Young's modulus.

Unveiling the Potential of Highly Porous Covalent Organic Frameworks for Water-Jet Rewritable Papers.

The massive use of paper has resulted in significant negative impacts on the environment. Fortunately, recent progress has been made in the field of rewritable paper, which has great potential in solving the increasing demand for paper while minimizing its environmental footprint. In this work, we report a green and economic strategy to develop ink-free rewritable paper by introducing hydrochromic covalent organic frameworks (COFs) in paper and using water as the sole trigger. When exposed to water or acidic solvents, two kinds of imino COFs change their colors reversibly from red to black. Additionally, a new visible absorption band appears, indicating that it can be transformed into another structure reversibly. This reversibility may be due to the isomerization from the diiminol to an iminol/cisketoenamine and its inability to doubly tautomerize to a diketoenamine. Specifically, we prepared the rewritable paper by loading these two COFs onto filter paper by using the decompression filtration method. When exposed to water, the paper undergoes a color change from red to black, which shows promising potential for applications in water-jet printing. Additionally, there is no significant performance degradation after 20 uses and 10 days between, further highlighting their potential as rewritable papers. To further improve its uniformity, we take the interface polymerization strategy to yield highly crystalline and more compact membranes, which are then transferred to paper to prepare writable papers. Our research has opened up a way for the application of COFs as a water-based printing material.

Using a Rapid Learning Health System for Stratified Care in Emerging Adult Mental Health Services: Protocol for the Implementation of Patient-Reported Outcome Measures.

BACKGROUND: Mental illness among emerging adults is often difficult to ameliorate due to fluctuating symptoms and heterogeneity. Recently, innovative approaches have been developed to improve mental health care for emerging adults, including (1) implementing patient-reported outcome measures (PROMs) to assess illness severity and inform stratified care to assign emerging adults to a treatment modality commensurate with their level of impairment and (2) implementing a rapid learning health system in which data are continuously collected and analyzed to generate new insights, which are then translated to clinical practice, including collaboration among clients, health care providers, and researchers to co-design and coevaluate assessment and treatment strategies. OBJECTIVE: The aim of the study is to determine the feasibility and acceptability of implementing a rapid learning health system to enable a measurement-based, stratified care treatment strategy for emerging adults. METHODS: This study takes place at a specialty clinic serving emerging adults (age 16-24 years) in Calgary, Canada, and involves extensive collaboration among researchers, providers, and youth. The study design includes six phases: (1) developing a transdiagnostic platform for PROMs, (2) designing an initial stratified care model, (3) combining the implementation of PROMs with stratified care, (4) evaluating outcomes and disseminating results, (5) modification of stratified care based on data derived from PROMs, and (6) spread and scale to new sites. Qualitative and quantitative feedback will be collected from health care providers and youth throughout the implementation process. These data will be analyzed at regular intervals and used to modify the way future services are delivered. The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework is used to organize and evaluate implementation according to 3 key objectives: improving treatment selection, reducing average wait time and treatment duration, and increasing the value of services. RESULTS: This project was funded through a program grant running from 2021 to 2026. Ethics approval for this study was received in February 2023. Presently, we have developed a system of PROMs and organized clinical services into strata of care. We will soon begin using PROMs to assign clients to a stratum of care and using feedback from youth and clinicians to understand how to improve experiences and outcomes. CONCLUSIONS: This study has key implications for researchers and clinicians looking to understand how to customize emerging adult mental health services to improve the quality of care and satisfaction with care. This study has significant implications for mental health care systems as part of a movement toward value-based health care. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/51667.

Bibliometric analysis and visualization of top papers in dentistry from 2012 to 2022 based on essential science indicators.

OBJECTIVES: This study aims to analyze and visualize the top dental papers from 2012 to 2022 using data from essential science indicators (ESIs). MATERIALS AND METHODS: The present study was conducted using library and retrospective bibliometric analysis methods. Additionally, a science map has been created. Web of Science was searched on January 18, 2023. The results were limited to the top papers in ESIs. The bibliometric information of the top papers was evaluated. Next, the VOSviewer was used to perform a co-occurrence analysis and visualize data. RESULTS: The findings showed that Mariano Belén Sanz and Maurizio S. Tonetti were the top two authors. The University of London and the University of Bern had the highest number of articles. These articles were published in 55 journals. According to the analysis of keyword co-occurrence, the most frequently used keywords in the field of dentistry include "periodontitis," "dental implants," "periodontal disease," "mechanical properties," "peri-implantitis," "oral health," "dental caries," "dental materials," "3D printing." CONCLUSION: The findings of this study enable readers to pinpoint the authors, organizations, countries, and journals that have made the biggest contributions to the list of the most often cited dentistry papers. In medicine, bibliometric citation analysis is frequently used to assist researchers in learning the fundamentals of a subject and pinpoint subtopics of broad interest for additional study.

Cross-talk between Helicobacter pylori and gastric cancer: a scientometric analysis.

Background: Helicobacter pylori (HP) is considered a leading risk factor for gastric cancer (GC). The aim of this article is to conduct bibliometric and visual analysis to assess scientific output, identify highly cited papers, summarize current knowledge, and explore recent hotspots and trends in HP/GC research. Methods: A bibliographic search was conducted on October 24, 2023, to retrieve relevant studies on HP/GC research between 2003 and 2022. The search terms were attached to HP and GC. The main data were from the Web of Science Core Collection (WoSCC). Data visualization was performed using Biblioshiny, VOSviewer, and Microsoft Excel. Results: In HP/GC research, 1970 papers were retrieved. The total number of papers (Np) in HP/GC was growing from 2003 to 2022. China and Japan were in the leading position and made the most contributions to HP/GC. Vanderbilt University and the US Department of Veterans Affairs had the highest Np. The most productive authors were Peek Jr Richard M. and Piazuelo M Blanca. Helicobacter received the most Np, while Gastroenterology had the most total citations (TC). High-cited publications and keyword clustering were used to identify the current status and trends in HP/GC research, while historical citation analysis provided insight into the evolution of HP/GC research. The hot topics included the effect of HP on gastric tumorigenesis and progression, the pathogenesis of HP-induced GC (HP factors), and the mechanisms by which HP affects GC (host factors). Research in the coming years could focus on topics such as autophagy, gut microbiota, immunotherapy, exosomes, epithelial-mesenchymal transition (EMT), and gamma-glutamyl transpeptidase (GGT). Conclusion: This study evaluated the global scientific output in HP/GC research and its quantitative characteristics, identified the essential works, and collected information on the current status, main focuses and emerging trends in HP/GC research to provide academics with guidance for future paths.

Fluorescent Biomass-Based Platform for Detection of ClO- in Cells and Water-Soluble Systems.

The generation and presence of excessive hypochlorous acid derivative ionic form (ClO-) could cause various diseases, such as arteriosclerosis, DNA damage, and cardiovascular illness. It is a critical need to develop a highly sensitive sensor for reliable detection of ClO- in cells and water-soluble systems. In this work, a hydroxyl group has been introduced into the compound 2-amino-3-(((E)-4-(2-(2-(2-hydroxyethoxy)ethyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl)benzylidene)amino)maleonitrile (NDC) to increase its solubility in water, at the same time, the hydrazone unit was designed as a specific recognition group for the "off-on" fluorescence probe of ClO-. The probe NDC presents high selectivity, sensitivity, anti-interference, and low detection limit (67 nM) for ClO-. The recognition mechanism that ClO- breaks the C=N bond and forms the fluorescent compound 4-(2-(2-(2-hydroxyethoxy)ethyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl)benzaldehyde (ND-3) has been confirmed by time-of-flight mass spectrometry. The probe NDC presents a good performance in the actual test of water samples and can be designed as the test papers for the quick and convenient detection of ClO- range from 0 to 1 µM. Moreover, the practical application was demonstrated by the successful imaging of endogenous and exogenous ClO- in HeLa cells. Our fluorescent biomass-based platform opens vast possibilities for repeatability, sensitivity, and selectivity detection of ClO- in cells and water-soluble systems.

Editor-in-Chief articles of choice and comments at the year-end of 2023.

As the Editor-in-Chief of World Journal of Gastroenterology, every week prior to a new issue's online publication, I perform a careful review of all encompassed articles, including the title, clinical and/or research importance, originality, novelty, and ratings by the peer reviewers. Based on this review, I select the papers of choice and suggest pertinent changes (e.g., in the title) to the Company Editors responsible for publication. This process, while time-consuming, is very important for assuring the quality of publications and highlighting important articles that Readers may revisit.

Editor's Introduction: Best Papers from the 20th International Conference on Cognitive Modeling.

The International Conference on Cognitive Modelling is dedicated to understanding how the complex processes of the mind can be explained in terms of detailed inner processing. In this issue, we present four representative papers of this field of research from our 20th meeting, ICCM 2022. This meeting was our first hybrid meeting, with a virtual version happening July 11-15, 2022, and an in-person event from July 23-27, 2022, held in Toronto, Canada. The four papers presented here were the top-ranked papers across both the virtual and in-person events. Three of the papers develop novel computational theories about low-level components within the mind and how those components result in high-level phenomena such as motivation, anhedonia, and attention. The final paper demonstrates the use of cognitive modeling to develop novel explanations of a paired associate learning task, and uses those insights to develop and explain human performance in a more complex version of that task.

Systematic exploration of a decade of publications on psychiatric genetics in Latin America.

Psychiatric disorders have a great impact in terms of mortality, morbidity, and disability across the lifespan. Considerable effort has been devoted to understanding their complex and heterogeneous genetic architecture, including diverse ancestry populations. Our aim was to review the psychiatric genetics research published with Latin American populations from 2010 to 2019, and classify it according to country of origin, type of analysis, source of funding, and other variables. We found that most publications came from Brazil, Mexico, and Colombia. Also, local funds are generally not large enough for genome-wide studies in Latin America, with the exception of Brazil and Mexico; larger studies are often done in collaboration with international partners, mostly funded by US agencies. In most of the larger studies, the participants are individuals of Latin American ancestry living in the United States, which limits the potential for exploring the complex gene-environment interaction. Family studies, traditionally strong in Latin America, represent about 30% of the total research publications. Scarce local resources for research in Latin America have probably been an important limitation for conducting bigger and more complex studies, contributing to the reduced representation of these populations in global psychiatric genetics studies. Increasing diversity must be a goal to improve generalizability and applicability in clinical settings.

Synthesis of a super-low detection limit fluorescent probe for Al3+ and its application in fluorescence imaging of zebrafish and cells.

A novel fluorescent probe N'-(2-hydroxybenzylidene)-indole-3-formylhydrazine (JHK) was designed and synthesized based on the condensation reaction of indole-3-formylhydrazine and salicylaldehyde. The probe JHK solution could highly selectively recognize Al3+ by the obvious fluorescence enhancement (288-fold) after adding Al3+. And the probe solution with Al3+ had a very high fluorescence quantum yield (89.29 %). The detection limit was calculated to be 1.135 nM, which was significantly lower than many reported detection limits, indicating that the probe JHK had pretty good sensitivity. The ratio of JHK to Al3+ (1:1) and the sensing mechanism were determined by Job's plot, 1H NMR spectra, FTIR spectra, ESI-MS and Gaussian calculation. The probe solution and medium-speed filter paper were successfully used to make test papers for more convenient detection of Al3+. Furthermore, the probe JHK had been successfully applied to the detection of Al3+ in real water, zebrafish and living cells.

Bibliometric and visual analysis of hypoxic pulmonary hypertension from 2013 to 2022.

Hypoxic pulmonary hypertension (HPH) is caused by chronic persistent hypoxia, which leads to the continuous increase of pulmonary artery pressure and pulmonary vascular resistance. In recent years, there has been a substantial increase in research on HPH. To study the trends of HPH research over the last decade, we used WOSCC to search for relevant research on this topic, and dealt with the relevant information using VOSviewer, CiteSpace, and R-tool. Our results show that the number of publications on HPH has generally increased in the last decade, albeit not significantly, while the average number of citations has been declining year by year. Researchers from the USA top the list with 5498 publications, who widely cooperate with researchers from other countries, followed by those from China. Kurt R. Stenmark has an authoritative position in this field, ranking first with 635 citations. American Journal of Physiology Lung Cellular and Molecular Physiology and Pulmonary Circulation have published 151 articles on HPH in the last 10 years, but the former has higher impact factor and article quality. Circulation proved its leadership in this field with 8812 citations. Our findings reveal the trends in HPH research and should provide researchers with plenty of useful information.