ABSTRACT
Pathergy phenomenon is a non-specific tissue hyperreactivity reaction due to trauma and is a minor diagnostic criterion of Behcet's disease. In this study, 100 patients with a suspicion of Behcet's disease who were referred to Cerrahpasa Medical Faculty Dermatology department between 01.11.2014 and 31.01.2015 are included. Skin pathergy tests were applied to all the patients and results were evaluated by two dermatologists separately at 48th hour, each with naked eye and with dermatoscopy. Test results were scored on a scale of 0-6. At the end of the study, score results of naked eye and dermatoscopy for doctor number 1 were statistically similar. Same results applied for doctor number 2. However, naked eye results of doctor number 1 and 2 for the same patients were significantly different from each other (p 0.0372) and with dermatoscopy examination this difference was eliminated (p > 0.05). This study revealed that naked eye evaluation of pathergy test results can yield different results among different interpreters. Use of dermatoscopy during the evaluation process decreases interobserver variation and subjectivity of the test.
Subject(s)
Behcet Syndrome/pathology , Dermoscopy/standards , Physical Examination/standards , Adult , Behcet Syndrome/diagnosis , Clinical Competence/standards , Dermoscopy/methods , Female , Humans , Male , Middle Aged , Physical Examination/methods , Prospective StudiesABSTRACT
Pyoderma gangrenosum is a rare non-infectious neutrophilic dermatitis, whereas necrotizing fasciitis is a life-threatening bacterial soft tissue infection of the fascia and adjacent skin. As in the case described here after intramedullary nailing, the clinical appearance of both diseases can be similar. Because of the completely different therapeutic approach and a worse outcome in the case of false diagnosis, pyoderma gangrenosum should always be taken into consideration before treating necrotizing fasciitis.
Subject(s)
Fasciitis, Necrotizing/diagnosis , Fasciitis, Necrotizing/etiology , Fracture Fixation, Intramedullary/adverse effects , Prosthesis-Related Infections/diagnosis , Prosthesis-Related Infections/etiology , Tibial Fractures/surgery , Adult , Diagnosis, Differential , Female , Humans , Pyoderma Gangrenosum/diagnosis , Pyoderma Gangrenosum/etiology , Tibial Fractures/complications , Tibial Fractures/diagnosisABSTRACT
Pyoderma gangrenosum may be associated with underlying systemic diseases. The most frequently associated condition is inflammatory bowel disease. Other associations include chronic active and chronic persistent hepatitis, rheumatoid arthritis, leukemia, myeloma, ployarthritis, monoclonal gammopathy, myeloproliferative disorders, systemic lupus erythromatosus ad Behcet's disease. Multiple extensive pyoderma gangrenosum associatie with Behcet's disease has rerely been reported in Korea. Thus, we report a case of multiple pyoderma gangrenosums occurring as pathergy phenomenon at intravenous and intramuscular injection sites in a patient with Behcet's disease.
