Whoever wants better healthcare simply pays more: citizens' perception about voluntary private health insurance in Colombia.

OBJECTIVES: To explore the perceptions that Colombians have about voluntary private health insurance plans (VPHI) in the health system to identify the tensions that exist between the public and private systems. METHODS: A qualitative case study approach with 46 semi structured interviews of patients, healthcare workers, healthcare administrators, decision-makers, and citizens. Interviews were recorded, transcribed, anonymized, digitally stored, and analyzed following grounded theory guidelines. RESULTS: We developed a paradigmatic matrix that explores how, in a context mediated by both the commodification of health and social stratification, perceptions about the failures in the public health system related to lack of timely care, extensive administrative procedures, and the search for privileged care led to positioning VPHI as a solution to these failures. The interviewees identified three consequences of using VPHI: first, the worsening of problems of timely access to care in the public system; second, higher costs for citizens translated into double payment for technologies and services to which they are entitled; third, the widening of inequity gaps in access to health services between people with similar needs but different payment capacities. CONCLUSIONS: These findings can help decision makers to understand citizens´ perceptions about the implications that VPHI may have in worsening equity gaps in the Colombian health system. It also shows, how VPHI is perceived as a double payment for services covered within social security plans and suggests that the perceived lack of timely access to care in the public systems and the fear that citizens have for themselves or their family members when using suboptimal healthcare are important drivers to purchase these private insurances.

RESUMEN: OBJETIVOS: Explorar las percepciones que tienen los colombianos sobre los planes de seguro de salud privados voluntarios (VPHI) en el sistema de salud para identificar las tensiones que existen entre los sistemas público y privado. MéTODOS: Un estudio cualitativo de caso con 46 entrevistas semiestructuradas a pacientes, trabajadores de la salud, administradores de salud, tomadores de decisiones y ciudadanos. Las entrevistas se grabaron, transcribieron y almacenaron de manera anónima. El análisis se hizo siguiendo conceptos de la teoría fundamentada. RESULTADOS: Desarrollamos una matriz paradigmática que explora cómo, en un contexto mediado tanto por la mercantilización de la salud como por la estratificación social, las percepciones sobre las fallas en el sistema de salud público relacionadas con la falta de atención oportuna, procedimientos administrativos extensos y la búsqueda de atención privilegiada llevaron a posicionar los VPHI como una solución a estas fallas. Los entrevistados identificaron tres consecuencias del uso de los VPHI: primero, el empeoramiento de los problemas de acceso oportuno a la atención en el sistema público; segundo, mayores costos para los ciudadanos, traducidos en un pago doble por tecnologías y servicios a los que tienen derecho; tercero, el aumento de las brechas de equidad en el acceso a los servicios de salud entre personas con necesidades similares pero diferentes capacidades de pago. CONCLUSIONES: Estos hallazgos pueden ayudar a los tomadores de decisiones a comprender las percepciones de los ciudadanos sobre las implicaciones que el VPHI puede tener en el empeoramiento de las brechas de equidad en el sistema de salud colombiano. También muestra cómo el VPHI se percibe como un pago doble por servicios cubiertos dentro de los planes de seguridad social y sugiere que la falta percibida de acceso oportuno a la atención en los sistemas públicos y el miedo que los ciudadanos tienen por sí mismos o por sus familiares cuando utilizan una atención sanitaria subóptima son factores importantes para adquirir estos seguros privados.

Evaluation of a mechanistic model that estimates feed intake, growth and body composition, nutrient requirements, and optimum economic response of broilers.

Efficient meat production is crucial in addressing global market demands and sustainability goals. Modeling production systems has gained worldwide attention, offering valuable insights for predicting outcomes and optimizing economic returns. In the poultry industry, researchers have developed mathematical models to predict animal performance and maximize profits. These models incorporate theories to explain real-world processes and enable future event predictions. One such model is the Broiler Growth Model (BGM), which serves as a predictive tool for estimating feed intake, growth, and body composition of broilers. The BGM takes into account the genetic potential of the broilers, the feed they are provided, and several constraining factors that may prevent the animal from achieving their genetic potential. To evaluate the BGM, a series of simulations were performed: (i) model behavior was evaluated by simulating the response of males and females from 22 to 35 d to feeds differing in dietary protein content and nutrient density; (ii) model prediction was evaluated using the results of a protein response trial conducted at UNESP in which six dietary protein levels were fed to male and female broilers over a 56 d period; and (iii) model optimization was used to maximize economic returns in the above trial. The model behaved as expected when feeds differing in protein content were fed, with feed intake per kg of BW increasing as protein level was decreased, resulting in lower gains and higher body lipid contents. Increasing nutrient density resulted in higher feed intake in the second level, followed by a reduction in feed intake in the highest nutrient feed. The simulated response to nutrient density resulted in increasing body lipid deposition as the nutrient density increased. In comparing the simulated and actual results of the protein response trial, the overall error of prediction was up to 15% for feed intake, BW, and body protein. The optimization routine allows the simulation of different economic scenarios, helping in decision-making. The Broiler Growth Model emerges as a valuable tool for the poultry industry, offering predictive capabilities and economic optimization potential. While minor discrepancies between simulated and actual results exist, the BGM holds significant promise for enhancing efficiency and profitability in broiler production, contributing to the broader goals of sustainable broiler meat production.

Economic valuations for technical indicators in sheep production / Valoração econômica para indicadores técnicos na produção de ovinos

The objectives of this work were to identify and model the interrelationships among zootechnical indicators manifested in sheep production from an intensive system in Brazil and to ascertain the impact of these indicators on the economic and productive outcomes from management operations. To this end, two multiple regression models were developed to determine which indicators had influence, and in what proportion, on the quantity of kilograms of lambs sold in the system. In order to determine the effects of the FAMACHA© scores on ewes during breeding and lambing, as related to the production quantity in kilograms of weaned sheep, two analyses of one-factor variance were designed, in which the absolute (AEV) and relative (REV) economic values were assigned to zootechnical indicators. This approach was taken in order to verify which indices have the greatest effects on profit and, consequently, should be prioritized in the selection criteria. The primary indicators were found to be the prolificacy, ewe weight at lambing, ewe age at lambing, average daily gain, offspring survival and the FAMACHA© score of the ewe at birth and at lambing; their significance (P<0.05) determined the number of kilograms of lambs produced in the system. The indicator with the highest AEV and REV was the age of the ewe at lambing, with US$ 3.78 year-1 ewe-1and 54.09%, respectively. FAMACHA© score 1 provided the highest return to the system, with an absolute economic value of US$ 1.09 ewe-1 at breeding and US$ 1.71 ewe-1 at lambing. Scores 4 and 5 caused damage to both breeding and lambing, with -US$ 1.15 ewe-1 and -US$ 1.44 ewe-1 for score 4, and -US$ 1.24 ewe-1 and -US$ 1.76 ewe-1 for score 5 at breeding and at lambing, respectively. The findings indicated that the producer can manipulate the flock culling rate to increase the age of the dams in order to guarantee a greater productivity of sheep. Another indication would be to apply selection criteria to ensure an increase in the number of superior animals present in the system, especially animals that are resilient to worms. This strategy can facilitate increased profits without the need to significantly increase expenditure on inputs.

Os objetivos deste trabalho foram de identificar e modelar as inter-relações entre indicadores zootécnicos utilizados na produção de ovinos, em um sistema intensivo no Brasil, e verificar o impacto desses indicadores nos resultados econômicos e produtivos da propriedade. Para tanto, foram desenvolvidos dois modelos de regressão múltipla para determinar quais indicadores influenciaram, e em que proporção, a quantidade de quilogramas de cordeiros vendidos no sistema. A fim de determinar os efeitos dos graus FAMACHA© das ovelhas durante a monta e parto, em relação à quantidade de produção em quilogramas de cordeiros desmamados, foram realizadas duas análises de variância de um fator, nas quais valores econômicos absoluto (VEA) e relativo (VER) foram atribuídos aos indicadores zootécnicos. Essa abordagem foi feita com o objetivo de verificar quais índices têm maiores efeitos no lucro e, consequentemente, devem ser priorizados nos critérios de seleção. Os principais indicadores foram a prolificidade, peso da ovelha ao parto, idade da ovelha ao parto, ganho médio diário, sobrevivência da prole e grau FAMACHA© da ovelha ao nascimento e ao parto; sua significância (P<0,05) determinou o número de quilogramas de cordeiros produzidos no sistema. O indicador com maior VEA e VER foi a idade da ovelha ao parto, com US$ 3,78 ano-1 ovelha-1 e 54,09%, respectivamente. O grau FAMACHA© 1 proporcionou o maior retorno ao sistema, com valor econômico absoluto de US$ 1,09 ovelha-1 na monta e US$ 1,71 ovelha-1 no parto. Os graus 4 e 5 causaram prejuízos tanto à monta quanto ao parto, com -US$ 1,15 ovelha-1 e -US$ 1,44 ovelha-1 para o grau 4, e -US$ 1,24 ovelha-1 e -US$ 1,76 ovelha-1 para o grau 5 na monta e no parto, respectivamente. Os resultados indicaram que o produtor pode manipular a taxa de descarte do rebanho para aumentar a idade das matrizes a fim de garantir uma maior produtividade das ovelhas. Outra indicação seria a aplicação de critérios de seleção para garantir o aumento do número de animais superiores presentes no sistema, principalmente animais resistentes a helmintoses. Essa estratégia pode facilitar o aumento dos lucros sem a necessidade de aumentar significativamente os gastos com insumos.

A Call to Action Against Persistent Lack of Transparency in Vaccine Pricing Practices During the COVID-19 Pandemic.

Lack of transparency in vaccine pricing practices is a problem that has been under discussion for a long time. To tackle this, the World Health Assembly adopted the resolution Improving the transparency of markets for medicines, vaccines, and other health products in 2019. However, despite the appalling effects of the current pandemic and the unequal global distribution of vaccines, the 2019 resolution has not been included as a fundamental pillar in the global health response to COVID-19. Governments and public health agencies have provided public funding to pharmaceutical companies for research and development of new vaccines. Yet, information on pricing strategies and methodologies is still inaccessible. Furthermore, these companies are profiting from publicly funded research and development. But secrecy and opacity prevails in the pharmaceutical industry, affecting low and middle income countries. Situating the demand for transparency, accountability and fair pricing of pharmaceutical products as a global health justice issue, I suggest an independent global observatory for accountability and transparency in the pharmaceutical global market should be created to help international organizations, governments and civil society in their quest for affordable and safe vaccines and therapeutics.

Assessment of the environmental impact and economic performance of cacao agroforestry systems in the Ecuadorian Amazon region: An LCA approach.

Ecuador is the third largest cacao exporter in the world. Up to 10 % of Ecuador's cacao production is grown in the Amazon region, mostly under conventional (CA) and organic (OA) agroforestry systems. Despite the importance of cacao in this area, no previous studies on its environmental impact and economic viability have yet been carried out. The main objective of this research is to fill this gap and, more specifically, perform a comparative analysis between CA and OA systems. For this purpose, primary information was gathered from 90 farms (44 conventional and 46 organic ones) that implement land management practices. The environmental performance of cacao production was assessed using a life cycle analysis methodology, with a cradle-to-farm gate approach. Up to twelve impact categories and five environmental and monetary efficiency indicators were estimated based on three functional units (1 kg of cacao, 1 kg of output sold, and 1 ha). Additionally, an economic viability analysis was performed, focused on profitability. The results show that organic management allows to reduce the environmental impact in all the analyzed categories, except for the land footprint, and improved the environmental and economic efficiency of agroforestry systems. The economic analysis shows no statistically significant differences between CA and OA profitability (net margin), which can be improved by selling co-products. Despite the low environmental impact of both types of system, economic profitability is certainly one of the weaknesses of cacao production in the Ecuadorian Amazon region. This study contributes to develop technical, production-related and political actions that could improve the economic cacao production situation without jeopardizing the environmental benefit obtained by these systems.

Reflections on activism, the academy and the Non-Profit Industrial Complex in Colombia: What a revolutionary ethos might look like.

This essay brings together different voices to reflect on several participatory research projects carried out in Colombia, based on human rights, 'empowerment', harm reduction, (im)mobility and forced migration, gendered and political violence, armed conflict, and the right to health of people in the social margins. We look back on nine years of activism to explore the foundations of what our friendships and relationships have come to know as a revolutionary ethos. We critically re-visit and reflect on the concept of 'the activist' in the realms of the human rights apparatus in Colombia, the academy and the Non-Profit Industrial Complex (NPIC). We look back on what was forged and what was lost to propose the critical concept of 'radical honesty and self-care' as the basis for a revolution that supports processes of healing and social justice. Finally, we imagine what 'healing' can look like, as committed activists despite our differences and positionalities. We engage with and problematise the different forms of activism that emerge in social struggles and we address self-criticisms, constant reflection, radical honesty and uncomfortableness as powerful tools in joining forces to continue social justice work and caring.

Disparity between scientific accomplishment and biotechnology availability in Brazil.

Despite being among the world's leaders in scientific output, Brazil ranks 66th among countries in the production of reagents and supplies needed for state-of-the-art scientific analyses. The production of needed reagents and equipment for experimental analyses and patient diagnostics is sorely lacking within Brazil and explicit in this pandemic period caused by SARS-CoV-2. A significant fraction of resources from Brazilian funding agencies is now being transferred to companies in other countries for the purchase of essential scientific-related products. Is this sustainable? Therefore it is necessary to draw the attention of all the world and Brazilian society about this situation.

Relationship among productive and economic variables of beef cattle in Brazil / Relações entre variáveis produtivas e econômicas de bovinocultura de corte no Brasil

The present study aimed to obtain, through statistical methods, the independent variables that influence the economic and productive results of Brazilian beef cattle. Economic and productive information was collected from 106 farms in Brazil. Data collection was performed by the Instituto de Métricas Agropecuárias (Inttegra). The variable selection method used was stepwise regression followed by polynomial regression analyses. The variable beef cattle economic result showed the positive effect of disbursement per head per month and average weight gain. An average daily gain of 520 g in live weight was obtained, and this variable was influenced especially by nutrition cost. The arroba production (arroba is a unit of weight corresponding to 15kg) was influenced by the linear effect of nutrition cost and stocking rate. The variable arroba production in pasture showed a linear and positive effect of average weight gain in pasture and stocking rate in pasture. For profit per arroba, the variables nutrition cost, disbursement with pasture, and average sale price had a linear effect. The independent variables that had the greatest influence on the response variables were stocking rate, average daily weight gain, and nutrition cost. Thus, increases in investment in nutrition and stocking rate should result in higher production rates and improvements in the profitability of this activity.(AU)

O presente trabalho teve como objetivo obter, por meio de métodos estatísticos, quais variáveis independentes influenciam as variáveis econômicas e produtivas na bovinocultura de corte brasileira. O banco de dados utilizado foi obtido por coleta de informações econômicas e produtivas em 106 fazendas no Brasil. O método de coleta de dados foi definido pelo Instituto de Métricas Agropecuárias (Inttegra). Foram realizadas análises de seleção de variáveis pelo método Stepwise, seguido por análises de regressão múltipla. A variável resultado econômico da bovinocultura de corte teve efeito positivo do desembolso mensal por cabeça e do ganho de peso médio diário. Para o ganho de peso médio diário foi obtido um valor médio de 520 gramas, e esta variável foi influenciada principalmente pelo custeio com nutrição. Para a produção de arroba foi obtido efeito linear do custeio com nutrição e da taxa de lotação. Para a variável produção de arroba a pasto foi obtido um efeito linear e positivo do ganho médio diário de peso no pasto e da taxa de lotação no pasto. Para o lucro por arroba, as variáveis custeio com nutrição, desembolso com pastagem e preço médio de venda tiveram efeito linear. As variáveis independentes que tiveram maior influência nas variáveis resposta foram a taxa de lotação, o ganho médio diário de peso e o custeio com nutrição. Assim, aumentos no investimento em nutrição e na taxa de lotação dos animais devem resultar em maiores índices de produção e em melhorias na rentabilidade da atividade.(AU)

Relationship among productive and economic variables of beef cattle in Brazil / Relações entre variáveis produtivas e econômicas de bovinocultura de corte no Brasil

ABSTRACT: The present study aimed to obtain, through statistical methods, the independent variables that influence the economic and productive results of Brazilian beef cattle. Economic and productive information was collected from 106 farms in Brazil. Data collection was performed by the Instituto de Métricas Agropecuárias (Inttegra). The variable selection method used was stepwise regression followed by polynomial regression analyses. The variable beef cattle economic result showed the positive effect of disbursement per head per month and average weight gain. An average daily gain of 520 g in live weight was obtained, and this variable was influenced especially by nutrition cost. The arroba production (arroba is a unit of weight corresponding to 15kg) was influenced by the linear effect of nutrition cost and stocking rate. The variable arroba production in pasture showed a linear and positive effect of average weight gain in pasture and stocking rate in pasture. For profit per arroba, the variables nutrition cost, disbursement with pasture, and average sale price had a linear effect. The independent variables that had the greatest influence on the response variables were stocking rate, average daily weight gain, and nutrition cost. Thus, increases in investment in nutrition and stocking rate should result in higher production rates and improvements in the profitability of this activity.

RESUMO: O presente trabalho teve como objetivo obter, por meio de métodos estatísticos, quais variáveis independentes influenciam as variáveis econômicas e produtivas na bovinocultura de corte brasileira. O banco de dados utilizado foi obtido por coleta de informações econômicas e produtivas em 106 fazendas no Brasil. O método de coleta de dados foi definido pelo Instituto de Métricas Agropecuárias (Inttegra). Foram realizadas análises de seleção de variáveis pelo método Stepwise, seguido por análises de regressão múltipla. A variável resultado econômico da bovinocultura de corte teve efeito positivo do desembolso mensal por cabeça e do ganho de peso médio diário. Para o ganho de peso médio diário foi obtido um valor médio de 520 gramas, e esta variável foi influenciada principalmente pelo custeio com nutrição. Para a produção de arroba foi obtido efeito linear do custeio com nutrição e da taxa de lotação. Para a variável produção de arroba a pasto foi obtido um efeito linear e positivo do ganho médio diário de peso no pasto e da taxa de lotação no pasto. Para o lucro por arroba, as variáveis custeio com nutrição, desembolso com pastagem e preço médio de venda tiveram efeito linear. As variáveis independentes que tiveram maior influência nas variáveis resposta foram a taxa de lotação, o ganho médio diário de peso e o custeio com nutrição. Assim, aumentos no investimento em nutrição e na taxa de lotação dos animais devem resultar em maiores índices de produção e em melhorias na rentabilidade da atividade.

Design and Implementation Factors for Performance Measurement in Non-profit Organizations: A Literature Review.

Purpose: Performance measurement systems (PMS) in Non-profit Organizations (NPOs) are more complex than in for-profit organizations. NPOs have an orientation toward social mission and values, and they consider not only organizational efficiency and viability, but also the social impact of the organization. This research provides a comprehensive synthesis of PMSs in NPOs. Design/Methodology/Approach: Using a literature review, supported by bibliometric and network analyses. A paper set of 240 articles related to this research field is examined. Topics that are the most prevalent in this research area and their interrelationships are identified, presenting an outline of current efforts. Findings: Despite the descriptive analyses for the paper set, a framework is proposed for organizing the design-implementation factors of PMSs in non-profit organizations, identifying the main requirements for their successful development. Originality/Value: Investigation on performance measurement in non-profit organizations is still in its early stages of development with many opportunities to further develop the field. Conceptual frameworks and models, as well as specific theories, are being generated for this field of research, and the process of adapting models from the general field of performance measurement is taking place. The meta-framework that organizes the main research topics of PMS in non-profit organizations and the framework that consolidates factors that influence the design-implementation of PMSs in non-profit organizations developed represents this paper contribution.

Human Resource Management and Innovative Performance in Non-profit Hospitals: The Mediating Effect of Organizational Culture.

Literature suggests that human resources of non-profit hospitals (NPHs) present features that could potentially reach any expected organizational performance even when the attention to human resource management (HRM) are often low in non-profit organizations. Nowadays ambitious organizations strive to obtain a profitable performance that is also innovate and do it through building an organizational culture (OC), while for NPHs a positive culture is given by their human resources traits. However, there is not enough literature to understand how these three variables behave together. This study aims to explain the influence of HRM on IP mediated by OC. The research model was assessed through Partial Least Squares Structural Equation Modeling (PLS-SEM). The results support all the stated hypotheses. Both, HRM and OC are moderately strong predictors of IP, and OC mediates partially and in a complementary way the relationship between HRM on IP. An importance-performance map analysis (IPMA) was performed to expand the PLS-SEM results. The OC indicators show greater importance to explain IP, consequently, they are the most relevant indicators to initiate management actions by NPHs. The influence of HRM on IP represent an opportunity for NPH as it implies an affordable investment in comparison to the cost of technological solutions for enterprises.

Produtividade de milho e retorno econômico em sistema integrado de produção com doses de nitrogênio / Maize yield and economic return in integrated production system with doses of nitrogen

O milho é altamente exigente e responsivo à adubação com nitrogênio (N), estando inserido em vários sistemas produtivos, com destaque recente para os sistemas integrados de produção. Assim, objetivou-se avaliar o efeito de doses de N sob o milho, bem como o aspecto econômico em sistema integrado. O delineamento experimental utilizado foi de blocos ao acaso com quatro repetições. Foram avaliadas quatro doses de N em cobertura (0, 40, 80 e 120 kg ha-1). O milho foi cultivado sob palhada do consórcio de aveia e azevém. Verificou-se que diâmetro do colmo, altura de inserção da espiga, e características da espiga, com exceção do número de fileiras por espiga aumentaram linearmente em função das doses de N, por sua vez, a altura da planta respondeu de forma quadrática até a dose de 81 kg ha-1 de N. A produtividade aumentou de forma expressiva em função do N, indicando efeito residual da adubação no inverno e elevada eficiência de uso do N no sistema produtivo. A maior produtividade e lucratividade foram obtidas na dose de 120 kg ha-1 N.(AU)

Maize is highly demanding and responsive to nitrogen (N) fertilization, inserted in several production systems, with the recent highlight for integrated production systems. This study aimed to assess the effect of N rates on maize, as well as the economic aspect in an integrated production system. The experimental design was a randomized complete block design with four replicates. Four N rates in topdressing (0, 40, 80, and 120 kg ha-1) were assessed. Maize was cultivated under black oat and ryegrass mixed straw. Stem diameter, main ear insertion height, and ear parameters, except for the number of rows per ear, which increased linearly as a function of N rates, in turn, plant height responded quadratically until 81 kg N ha-1. Grain yield increased significantly as a function of N, indicating a residual effect of winter fertilization and high N use efficiency in the production system. The highest grain yield and profitability were obtained at the rate of 120 kg N ha-1.(AU)

Produtividade de milho e retorno econômico em sistema integrado de produção com doses de nitrogênio / Maize yield and economic return in integrated production system with doses of nitrogen

O milho é altamente exigente e responsivo à adubação com nitrogênio (N), estando inserido em vários sistemas produtivos, com destaque recente para os sistemas integrados de produção. Assim, objetivou-se avaliar o efeito de doses de N sob o milho, bem como o aspecto econômico em sistema integrado. O delineamento experimental utilizado foi de blocos ao acaso com quatro repetições. Foram avaliadas quatro doses de N em cobertura (0, 40, 80 e 120 kg ha-1). O milho foi cultivado sob palhada do consórcio de aveia e azevém. Verificou-se que diâmetro do colmo, altura de inserção da espiga, e características da espiga, com exceção do número de fileiras por espiga aumentaram linearmente em função das doses de N, por sua vez, a altura da planta respondeu de forma quadrática até a dose de 81 kg ha-1 de N. A produtividade aumentou de forma expressiva em função do N, indicando efeito residual da adubação no inverno e elevada eficiência de uso do N no sistema produtivo. A maior produtividade e lucratividade foram obtidas na dose de 120 kg ha-1 N.

Maize is highly demanding and responsive to nitrogen (N) fertilization, inserted in several production systems, with the recent highlight for integrated production systems. This study aimed to assess the effect of N rates on maize, as well as the economic aspect in an integrated production system. The experimental design was a randomized complete block design with four replicates. Four N rates in topdressing (0, 40, 80, and 120 kg ha-1) were assessed. Maize was cultivated under black oat and ryegrass mixed straw. Stem diameter, main ear insertion height, and ear parameters, except for the number of rows per ear, which increased linearly as a function of N rates, in turn, plant height responded quadratically until 81 kg N ha-1. Grain yield increased significantly as a function of N, indicating a residual effect of winter fertilization and high N use efficiency in the production system. The highest grain yield and profitability were obtained at the rate of 120 kg N ha-1.

Association between technical and economic performance indexes and dairy farm profitability

This study aimed to evaluate the determinant profitability indexes of typical dairy farms located in Brazil. The empirical sample included detailed technical and financial information of 61 Brazilian dairy farms across a longitudinal data set (10 years). Numerous technical and economic indexes were estimated, and Pearson's correlation coefficients were calculated to determine the relationship between each index and profitability. After selecting the significant indexes, regression equations were generated to determine the relationship between each index and profitability. The results of the analysis revealed significant interactions between different combinations of technical and financial indexes. Milk production per lactating cow and area were the indexes most positively correlated with profitability. In contrast, total unit cost in relation to the price of milk, total operating cost in relation to total revenues, and total unit operating cost in relation to the price of milk were the indexes most negatively correlated with profitability. Overall, these results indicate that profits could significantly increase if dairy farm production is conducted with more intensive use of inputs and production factors and better combinations of inputs and outputs.(AU)

Uruguayan Cannabis Social Clubs: From activism to dispensaries?

BACKGROUND: In 2013 Uruguay regulated three models for the supply of cannabis for recreational use (Law 19.172), including Cannabis Social Clubs (CSCs). According to the Cannabis Regulation and Control Institute, 110 CSCs are active at the time of writing. OBJECTIVES: This paper has a twofold goal. Firstly, it aims to take stock of how the CSC model has continued to be implemented in practice, drawing on the first-hand accounts of those involved in its management. Secondly, our analysis seeks to contribute to the understanding of the CSC model by considering the different variants of the model that have emerged in Uruguay. METHODOLOGY: Our analysis draws on qualitative research conducted in Uruguay between June and October of 2018. We conducted 15 semi-structured and face-to-face interviews with representatives of registered Uruguayan CSCs and with 13 other stakeholders. RESULTS/CONCLUSIONS: CSCs' role as cannabis suppliers is perceived positively in terms of the type of cannabis produced and the means of distribution. We found that truly social CSCs co-exist with, and may be losing ground to, quasi-dispensary clubs. A number of factors may have contributed to this, including the Uruguayan regulatory framework, institutional context, and disengagement of members and/or CSC managers. This raises potential new challenges as to the contribution of the CSC model from a harm reduction perspective.

Economic Method for Extraction/Purification of a Burkholderia cepacia Lipase with Potential Biotechnology Application.

In order to recover biomolecules, a single downstream processing step is carried out. In this sense, an aqueous two-phase system (ATPS) containing polyethylene glycol (PEG) and potassium phosphate salts is used. Intending the purification of Burkholderia cepacia (Bc) lipase, the effects of the molecular masses of 1500 (PEG 1500), 4000 (PEG 4000), and 6000 (PEG 6000), pH (6, 7, and 8) and distinct tie line lengths are perfomed. Although this is reasonable reported in literature, a study covering an economical production aspect considering the Bc is scarce. This characterizes a novelty proposed in this investigation. Lipase is recovered in a polymer phase at lower pH value. PEG 1500/phosphate salt ATPS at pH 6 is considered a good method with ~ 98% of the extraction efficiency. Another contribution of this proposed investigation concerns to a biotechnological material synthesis, which is applied in several advanced and revolutionize engineering practices. Additionally, an economic analysis of the proposed method indicates a minimal sale price (~ US$410/L) inducing to a future and potential commercial application.

Performance and Egg Quality of Commercial Laying Hens Fed Diets Formulated Using Non-Linear Programming

Feed formulation using linear programming consists of determining the mixture of feedstuffs required to meet pre-established animal nutritional requirements at the lowest cost. On the other hand, with the use of non-linear programming, it is possible to define nutritional requirements at the time of formulation, aiming at maximum profit. The objective of the present study was to compare feeds formulated using linear and non-linear programming in terms of live performance and internal and external egg quality of commercial laying hens. A total of 288 Hisex® White laying hens, 1.540 ± 0.128 g body weight, were evaluated from 33 to 45 weeks of age. Hens were distributed in a completely randomized block design, including six treatments with six replicates of eight birds each. Three treatments consisted of feeds formulated using linear programming and based on the nutritional requirements of Rostagno et al. (2011), of the genetic strain manual, or mathematical models to maximize performance. The other three treatments consisted of feeds formulated using non-linear programming considering typical, favorable, or unfavorable market scenarios. Data were submitted to analysis of variance, and in case of significance (p 0.05), means were grouped using the Scott-Knott test (5%).The treatments did not influence (p>0.05) Haugh unit, albumen height, or external egg quality parameters. Treatment effects (p 0.05) on yolk weight, albumen weight, yolk color, yolk percentage, albumen percentage, and performance parameters were described. In general, feeds formulated using linear programming and based on nutritional requirements obtained by mathematical models and the genetic strain manual promoted better performance results because the feeds were nutritionally denser. However, the treatments that maximized live performance did not result in higher profitability, which was obtained with the diet formulated for a favorable market scenario using non-linear programming.(AU)

Performance and Egg Quality of Commercial Laying Hens Fed Diets Formulated Using Non-Linear Programming

Feed formulation using linear programming consists of determining the mixture of feedstuffs required to meet pre-established animal nutritional requirements at the lowest cost. On the other hand, with the use of non-linear programming, it is possible to define nutritional requirements at the time of formulation, aiming at maximum profit. The objective of the present study was to compare feeds formulated using linear and non-linear programming in terms of live performance and internal and external egg quality of commercial laying hens. A total of 288 Hisex® White laying hens, 1.540 ± 0.128 g body weight, were evaluated from 33 to 45 weeks of age. Hens were distributed in a completely randomized block design, including six treatments with six replicates of eight birds each. Three treatments consisted of feeds formulated using linear programming and based on the nutritional requirements of Rostagno et al. (2011), of the genetic strain manual, or mathematical models to maximize performance. The other three treatments consisted of feeds formulated using non-linear programming considering typical, favorable, or unfavorable market scenarios. Data were submitted to analysis of variance, and in case of significance (p 0.05), means were grouped using the Scott-Knott test (5%).The treatments did not influence (p>0.05) Haugh unit, albumen height, or external egg quality parameters. Treatment effects (p 0.05) on yolk weight, albumen weight, yolk color, yolk percentage, albumen percentage, and performance parameters were described. In general, feeds formulated using linear programming and based on nutritional requirements obtained by mathematical models and the genetic strain manual promoted better performance results because the feeds were nutritionally denser. However, the treatments that maximized live performance did not result in higher profitability, which was obtained with the diet formulated for a favorable market scenario using non-linear programming.

La responsabilidad social corporativa y su rol en las empresas ecuatorianas / The corporate social responsibility and its role in ecuadorian enterprises / La responsabilidad social corporativa e su rol em las empresas ecuatorianas

Resumen Introducción: La presente investigación tiene como objetivo definir la aplicación de la responsabilidad social corporativa en el Ecuador, dado que representa una decisión voluntaria de las empresas para mejorar las condiciones de los grupos de interés con el fin de obtener también beneficios económicos a futuro. En Ecuador la RSC todavía es poco aplicado y generalmente se aplica de manera filantrópica o cuidado al medio ambiente, por lo que aún el término no se encuentra arraigado a los valores y objetivos corporativos. La metodología: usada tiene un enfoque mixto cuali-cuantitativo a través una investigación de tipo exploratoria, descriptiva y documental con un método inductivo-deductivo. Como Resultados: se determinó que en materia de RSC el Ecuador aún se encuentra analizando y probando los beneficios que ofrece la RSC. Sin embargo, se concluye que cada vez más las empresas empiezan a valorar los propósitos de la responsabilidad social y demuestran interés en implementarlo en las organizaciones.

Abstract Introduction: The objective of this research is to Objective. define the application of corporate social responsibility in Ecuador, since it represents a voluntary decision by companies to improve the conditions of interest groups in order to obtain future economic benefits. In Ecuador, CSR is still poorly applied and is generally applied in a philanthropic manner or with care for the environment, so that the term is not yet rooted in corporate values and objectives. Materials and methods: The methodology used has a mixed qualitative-quantitative approach through exploratory, descriptive and documentary research with an inductive-deductive method. Results: As a result, it was determined that in terms of CSR, Ecuador is still analyzing and testing the benefits offered by CSR. Conclusion: However, it is concluded that more and more companies begin to value the purposes of social responsibility and show interest in implementing it in organizations.

Resumo Introdução: O objetivo desta pesquisa é Objetivo. definir a aplicação da responsabilidade social corporativa no Equador, uma vez que representa uma decisão voluntária das empresas de melhorar as condições dos grupos de interesse para obter benefícios econômicos futuros. No Equador, a RSC ainda é pouco aplicada e geralmente aplicada de maneira filantrópica ou com cuidado com o meio ambiente, de modo que o termo ainda não está enraizado nos valores e objetivos corporativos. Materiais e métodos: A metodologia utilizada possui abordagem qualitativa-quantitativa mista por meio de pesquisa exploratória, descritiva e documental, com método indutivo-dedutivo. Resultados: Como resultado, foi determinado que, em termos de RSE, o Equador ainda está analisando e testando os benefícios oferecidos pela RSC. Conclusão: No entanto, conclui-se que mais e mais empresas começam a valorizar os objetivos de responsabilidade social e demonstram interesse em implementá-lo nas organizações.

Estimating apparent survival of songbirds crossing the Gulf of Mexico during autumn migration.

Many migratory bird species are declining, and the migratory period may limit populations because of the risk in traversing large geographical features during passage. Using automated radio-telemetry, we tracked 139 Swainson's thrushes (Catharus ustulatus) departing coastal Alabama, USA and crossing the Gulf of Mexico to arrive in the Yucatan Peninsula, Mexico during autumn. We estimated apparent survival and examined how extrinsic (weather variables and day of year) and intrinsic (fat load, sex and age) factors influenced survival using a mark-recapture approach. We also examined how favourability of winds for crossing the Gulf varied over the past 25 years. Fat load, day of year and wind profit were important factors in predicting which individuals survived crossing the Gulf. Survival estimates varied with wind profit and fat, but generally, fat birds departing on days with favourable wind profits had an apparent survival probability of greater than 0.90, while lean individuals with no or negative wind profits had less than 0.33. The proportion of favourable nights varied within and among years, but has increased over the last 25 years. While conservation strategies cannot improve extrinsic factors, they can provide opportunities for birds to refuel before crossing large geographical features through protecting and creating high-quality stopover sites.